PubRank

Job Dekker

Author PubWeight™ 279.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007 75.09
2 Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009 29.83
3 The accessible chromatin landscape of the human genome. Nature 2012 16.86
4 Mediator and cohesin connect gene expression and chromatin architecture. Nature 2010 14.34
5 Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements. Genome Res 2006 13.32
6 A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 2011 11.59
7 Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature 2012 9.75
8 The long-range interaction landscape of gene promoters. Nature 2012 9.20
9 Architectural protein subclasses shape 3D organization of genomes during lineage commitment. Cell 2013 6.37
10 Quantitative analysis of chromosome conformation capture assays (3C-qPCR). Nat Protoc 2007 6.28
11 Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Mol Cell 2005 5.77
12 Iterative correction of Hi-C data reveals hallmarks of chromosome organization. Nat Methods 2012 4.26
13 An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol 2012 4.15
14 Spatial organization of the mouse genome and its role in recurrent chromosomal translocations. Cell 2012 4.02
15 The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation. Mol Cell 2011 3.61
16 The hierarchy of the 3D genome. Mol Cell 2013 3.54
17 Organization of the mitotic chromosome. Science 2013 3.50
18 A mechanical basis for chromosome function. Proc Natl Acad Sci U S A 2004 3.48
19 The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules. Nat Struct Mol Biol 2010 3.39
20 Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A 2014 3.35
21 My5C: web tools for chromosome conformation capture studies. Nat Methods 2009 2.96
22 Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex. Nat Cell Biol 2007 2.72
23 Mapping networks of physical interactions between genomic elements using 5C technology. Nat Protoc 2007 2.69
24 Genomics tools for unraveling chromosome architecture. Nat Biotechnol 2010 2.63
25 Long-range chromosomal interactions and gene regulation. Mol Biosyst 2008 2.56
26 Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery. Genes Dev 2009 2.13
27 Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments. Genome Res 2013 2.05
28 Hi-C: a comprehensive technique to capture the conformation of genomes. Methods 2012 2.00
29 The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications. Proc Natl Acad Sci U S A 2006 2.00
30 MORC family ATPases required for heterochromatin condensation and gene silencing. Science 2012 1.97
31 Mapping chromatin interactions by chromosome conformation capture. Curr Protoc Mol Biol 2006 1.95
32 Integrating one-dimensional and three-dimensional maps of genomes. J Cell Sci 2010 1.92
33 Mapping cis- and trans- chromatin interaction networks using chromosome conformation capture (3C). Methods Mol Biol 2009 1.78
34 Sister cohesion and structural axis components mediate homolog bias of meiotic recombination. Cell 2010 1.76
35 Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease. Proc Natl Acad Sci U S A 2010 1.72
36 Hi-C: a method to study the three-dimensional architecture of genomes. J Vis Exp 2010 1.67
37 Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome. Genome Res 2012 1.63
38 High-throughput genome scaffolding from in vivo DNA interaction frequency. Nat Biotechnol 2013 1.53
39 Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods? Bioessays 2013 1.45
40 Enhanced yeast one-hybrid assays for high-throughput gene-centered regulatory network mapping. Nat Methods 2011 1.41
41 Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene. Nucleic Acids Res 2010 1.36
42 Yeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions. PLoS Genet 2009 1.36
43 Disease-causing 7.4 kb cis-regulatory deletion disrupting conserved non-coding sequences and their interaction with the FOXL2 promotor: implications for mutation screening. PLoS Genet 2009 1.32
44 HiTC: exploration of high-throughput 'C' experiments. Bioinformatics 2012 1.29
45 Analysis of long-range chromatin interactions using Chromosome Conformation Capture. Methods 2012 1.23
46 Determining spatial chromatin organization of large genomic regions using 5C technology. Methods Mol Biol 2009 1.23
47 Evidence for transcript networks composed of chimeric RNAs in human cells. PLoS One 2012 1.16
48 Structural organization of the inactive X chromosome in the mouse. Nature 2016 1.15
49 Yeast one-hybrid assays for gene-centered human gene regulatory network mapping. Nat Methods 2011 1.12
50 Chromatin globules: a common motif of higher order chromosome structure? Curr Opin Cell Biol 2011 1.12
51 3C-based technologies to study the shape of the genome. Methods 2012 1.11
52 Chromosome conformation capture carbon copy technology. Curr Protoc Mol Biol 2007 1.09
53 A mechanism for Ikaros regulation of human globin gene switching. Br J Haematol 2008 1.00
54 Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny. Genes Dev 2013 0.92
55 From cells to chromatin: capturing snapshots of genome organization with 5C technology. Methods 2012 0.89
56 The context of gene expression regulation. F1000 Biol Rep 2012 0.85
57 Biological techniques: Chromosomes captured one by one. Nature 2013 0.82
58 Genome architecture and expression. Curr Opin Genet Dev 2012 0.78
59 Gene dates, parties and galas. Symposium on Chromatin Dynamics and Higher Order Organization. EMBO Rep 2009 0.76
60 Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. Proc Natl Acad Sci U S A 2014 0.76
61 Translocation mapping exposes the risky lifestyle of B cells. Cell 2011 0.75
62 A Guide to Packing Your DNA. Cell 2016 0.75
63 The structure and function of chromatin and chromosomes. Pac Symp Biocomput 2012 0.75
64 Corrigendum: CTCF-mediated topological boundaries during development foster appropriate gene regulation. Genes Dev 2017 0.75