| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
PET of brain amyloid and tau in mild cognitive impairment.
|
N Engl J Med
|
2006
|
6.02
|
|
2
|
Human pharmacokinetic and dosimetry studies of [(18)F]FHBG: a reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression.
|
J Nucl Med
|
2001
|
3.03
|
|
3
|
Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography.
|
Proc Natl Acad Sci U S A
|
1999
|
2.71
|
|
4
|
Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir.
|
J Nucl Med
|
1998
|
2.58
|
|
5
|
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals.
|
Gene Ther
|
1999
|
2.21
|
|
6
|
Imaging transgene expression with radionuclide imaging technologies.
|
Neoplasia
|
2000
|
2.03
|
|
7
|
Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET.
|
J Nucl Med
|
1992
|
1.83
|
|
8
|
8-[18F]Fluoropenciclovir: an improved reporter probe for imaging HSV1-tk reporter gene expression in vivo using PET.
|
J Nucl Med
|
2001
|
1.80
|
|
9
|
Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease.
|
J Neurosci
|
2001
|
1.73
|
|
10
|
Novel observations with FDOPA-PET imaging after early nigrostriatal damage.
|
Mov Disord
|
2001
|
1.68
|
|
11
|
Monitoring gene therapy with reporter gene imaging.
|
Semin Nucl Med
|
2001
|
1.56
|
|
12
|
Quantification of target gene expression by imaging reporter gene expression in living animals.
|
Nat Med
|
2000
|
1.56
|
|
13
|
In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile.
|
Neuroscience
|
2003
|
1.38
|
|
14
|
Regioselective radiofluorodestannylation with [18F]F2 and [18F]CH3COOF: a high yield synthesis of 6-[18F]Fluoro-L-dopa.
|
Int J Rad Appl Instrum A
|
1992
|
1.15
|
|
15
|
Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction.
|
Gene Ther
|
2001
|
1.08
|
|
16
|
Whole body skeletal imaging with [18F]fluoride ion and PET.
|
J Comput Assist Tomogr
|
1993
|
1.07
|
|
17
|
Synthesis of 6-[18F] and 4-[18F]fluoro-L-m-tyrosines via regioselective radiofluorodestannylation.
|
Appl Radiat Isot
|
1993
|
0.99
|
|
18
|
Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors.
|
Gene Ther
|
2001
|
0.96
|
|
19
|
Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals.
|
Int J Rad Appl Instrum A
|
1989
|
0.94
|
|
20
|
Monitoring adenoviral DNA delivery, using a mutant herpes simplex virus type 1 thymidine kinase gene as a PET reporter gene.
|
Gene Ther
|
2002
|
0.92
|
|
21
|
Quantitative imaging of gene induction in living animals.
|
Gene Ther
|
2001
|
0.91
|
|
22
|
Remote, semiautomated production of 6-[18F]fluoro-L-dopa for human studies with PET.
|
Int J Rad Appl Instrum A
|
1990
|
0.91
|
|
23
|
Amyloid and tau imaging, neuronal losses and function in mild cognitive impairment.
|
J Nutr Health Aging
|
2008
|
0.84
|
|
24
|
Kinetics and modeling of L-6-[18F]fluoro-dopa in human positron emission tomographic studies.
|
J Cereb Blood Flow Metab
|
1991
|
0.84
|
|
25
|
A double-injection technique for in vivo measurement of dopamine D2-receptor density in monkeys with 3-(2'-[18F]fluoroethyl)spiperone and dynamic positron emission tomography.
|
J Cereb Blood Flow Metab
|
1989
|
0.83
|
|
26
|
3-(2'-[18F]fluoroethyl)spiperone: in vivo biochemical and kinetic characterization in rodents, nonhuman primates, and humans.
|
J Cereb Blood Flow Metab
|
1989
|
0.82
|
|
27
|
Detection and quantitation of 17F formation during the cyclotron production of 13N.
|
Int J Rad Appl Instrum A
|
1992
|
0.82
|
|
28
|
Blood-brain barrier and neuronal membrane transport of 6-[18F]fluoro-L-DOPA.
|
Biochem Pharmacol
|
2001
|
0.82
|
|
29
|
Proton irradiation of [18O]O2: production of [18F]F2 and [18F]F2 + [18F] OF2.
|
Nucl Med Biol
|
1996
|
0.79
|
|
30
|
Radiofluorinated L-m-tyrosines: new in-vivo probes for central dopamine biochemistry.
|
J Cereb Blood Flow Metab
|
1996
|
0.79
|
|
31
|
2Beta-carbomethoxy-3beta-(4- and 2-[18F]fluoromethylphenyl)tropanes: specific probes for in vivo quantification of central dopamine transporter sites.
|
Nucl Med Biol
|
1999
|
0.79
|
|
32
|
Nigrostriatal reduction of aromatic L-amino acid decarboxylase activity in MPTP-treated squirrel monkeys: in vivo and in vitro investigations.
|
J Neurochem
|
2000
|
0.79
|
|
33
|
6-[18F]fluoro-L-dopa probes dopamine turnover rates in central dopaminergic structures.
|
J Neurosci Res
|
1990
|
0.79
|
|
34
|
Modelling approach for separating blood time-activity curves in positron emission tomographic studies.
|
Phys Med Biol
|
1991
|
0.78
|
|
35
|
The synthesis of 2-[F-18]fluoro-2-deoxy-D-glucose using glycals: a reexamination.
|
J Nucl Med
|
1984
|
0.77
|
|
36
|
Metals suitable for fluorine gas target bodies: first use of aluminum for the production of [18F]F2.
|
Nucl Med Biol
|
1996
|
0.77
|
|
37
|
Distribution volume of 3-O-methyl-6.
|
J Cereb Blood Flow Metab
|
2000
|
0.77
|
|
38
|
Chemical reactivity of the 18F electrophilic reagents from the 18O(p,n) 18F gas target systems.
|
Nucl Med Biol
|
1996
|
0.76
|
|
39
|
Synthesis of 3beta-(4-[18F]fluoromethylphenyl)- and 3beta-(2-[18F] fluoromethylphenyl)tropane-2beta-carboxylic acid methyl esters: new ligands for mapping brain dopamine transporter with positron emission tomography.
|
Nucl Med Biol
|
1999
|
0.76
|
|
40
|
No-carrier-added 3-(2'-[18F]fluoroethyl)spiperone, a new dopamine receptor-binding tracer for positron emission tomography.
|
Int J Rad Appl Instrum B
|
1986
|
0.75
|
|
41
|
Synthesis of 4-[18F]fluoro-L-m-tyrosine: a model analog for the in vivo assessment of central dopaminergic function.
|
Int J Rad Appl Instrum A
|
1990
|
0.75
|
|
42
|
Models for in vivo kinetic interactions of dopamine D2-neuroreceptors and 3-(2'-[18F]fluoroethyl)spiperone examined with positron emission tomography.
|
J Cereb Blood Flow Metab
|
1989
|
0.75
|
|
43
|
Imaging and therapeutics: the role of neuronal transport in the regional specificity of L-DOPA accumulation in brain.
|
Mol Imaging Biol
|
2002
|
0.75
|
|
44
|
[18F]Fluoro-beta-fluoromethylene-m-tyrosine derivatives show stereo, geometrical, and regio specificities as in vivo central dopaminergic probes in monkeys.
|
Nucl Med Biol
|
1999
|
0.75
|
|
45
|
Distribution volume of radiolabeled large neutral amino acids in brain tissue.
|
J Cereb Blood Flow Metab
|
1998
|
0.75
|
|
46
|
Assessment of 18F gaseous releases during the production of 18F-fluorodeoxyglucose.
|
Health Phys
|
1991
|
0.75
|
|
47
|
Synthesis of stereo (R and S) and geometric (E and Z) isomers of [18F]fluoro-beta-fluoromethylene-m-tyrosine derivatives: in vivo probes of central dopaminergic function.
|
Nucl Med Biol
|
1999
|
0.75
|
|
48
|
Production of [18F]F2 using the 16O(3He,p)18F reaction.
|
Nucl Med Biol
|
1996
|
0.75
|
|
49
|
Stereospecific approach to the synthesis of [18F]2-deoxy-2-fluoro-D-mannose.
|
Int J Rad Appl Instrum A
|
1986
|
0.75
|
|
50
|
Striatal kinetic modeling of FDOPA with a cerebellar-derived constraint on the distribution of volume of 30MFD: a PET investigation using non-human primates.
|
J Cereb Blood Flow Metab
|
2000
|
0.75
|
|
51
|
L-6-[18F]fluoro-dopa metabolism in monkeys and humans: biochemical parameters for the formulation of tracer kinetic models with positron emission tomography.
|
J Cereb Blood Flow Metab
|
1991
|
0.75
|
|
52
|
Identification and quantitation of gaseous compounds of fluorine generated in [18F]F2 target systems.
|
Nucl Med Biol
|
1996
|
0.75
|