Published in Brain Res on February 08, 2005
1-Methyl-1,2,3,4-tetrahydroisoquinoline, an endogenous amine with unexpected mechanism of action: new vistas of therapeutic application. Neurotox Res (2013) 0.82
A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP. Br J Pharmacol (2012) 0.81
Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity. J Neuroimmunol (2010) 0.79
Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson's Disease. Neurotox Res (2015) 0.78
Comparison of the Effects of Acute and Chronic Administration of Tetrahydroisoquinoline Amines on the In Vivo Dopamine Release: A Microdialysis Study in the Rat Striatum. Neurotox Res (2016) 0.75
Effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the protective action of various antiepileptic drugs in the maximal electroshock-induced seizure model: a type II isobolographic analysis. J Neural Transm (Vienna) (2013) 0.75
1MeTIQ provides protection against Aβ-induced reduction of surface expression of synaptic proteins and inhibits H₂O₂-induced oxidative stress in primary hippocampal neurons. Neurotox Res (2013) 0.75
A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors. Cancer Res (2011) 4.22
The neuroblastoma-associated F1174L ALK mutation causes resistance to an ALK kinase inhibitor in ALK-translocated cancers. Cancer Res (2010) 3.16
Marginal decrease in mortality and marked increase in incidence as a result of neuroblastoma screening at 6 months of age: cohort study in seven prefectures in Japan. J Clin Oncol (2002) 1.63
Nras and Kras mutation in Japanese lung cancer patients: Genotyping analysis using LightCycler. Oncol Rep (2007) 1.62
Subcategorization of lung cancer based on tumor size and degree of visceral pleural invasion. Ann Thorac Surg (2008) 1.41
New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation. J Med Chem (2007) 1.32
PIK3CA gene amplification in Japanese non-small cell lung cancer. Lung Cancer (2007) 1.30
Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds. Toxicol Sci (2005) 1.29
Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A. Biochem Biophys Res Commun (2002) 1.27
Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter. Biochem Pharmacol (2002) 1.20
Drug-metabolizing ability of molybdenum hydroxylases. Drug Metab Pharmacokinet (2006) 1.19
Infant acute lymphoblastic leukemia with MLL gene rearrangements: outcome following intensive chemotherapy and hematopoietic stem cell transplantation. Blood (2004) 1.18
Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens. Toxicol Appl Pharmacol (2005) 1.13
Frequently increased epidermal growth factor receptor (EGFR) copy numbers and decreased BRCA1 mRNA expression in Japanese triple-negative breast cancers. BMC Cancer (2008) 1.09
Quinoline derivatives are therapeutic candidates for transmissible spongiform encephalopathies. J Virol (2004) 1.07
Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture. Toxicology (2005) 1.06
Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors. Genes Chromosomes Cancer (2002) 1.05
Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro. Eur J Pharmacol (2002) 1.02
EGFR R497K polymorphism is a favorable prognostic factor for advanced lung cancer. J Cancer Res Clin Oncol (2008) 1.01
Outcome of infants with neuroblastoma detected by mass screening and surgically treated in Shiga Prefecture, Japan: what is the role of surgery? Pediatr Surg Int (2002) 1.00
A case of retroperitoneal immature teratoma with nephroblastic components. J Pediatr Hematol Oncol (2012) 0.98
Epidermal growth factor receptor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer. J Cancer Res Clin Oncol (2007) 0.96
Expression and regulation of RB1CC1 in developing murine and human tissues. Int J Mol Med (2004) 0.96
Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics. J Med Chem (2010) 0.95
Tandospirone, a 5-HT1A agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions. Brain Res (2006) 0.95
KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung. Oncol Rep (2012) 0.95
Automation in drug inventory management saves personnel time and budget. Yakugaku Zasshi (2005) 0.95
Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo. Biochem Biophys Res Commun (2004) 0.94
Identification of prostatic-secreted proteins in mice by mass spectrometric analysis and evaluation of lobe-specific and androgen-dependent mRNA expression. J Endocrinol (2006) 0.94
Reductive metabolism of p,p'-DDT and o,p'-DDT by rat liver cytochrome P450. Drug Metab Dispos (2002) 0.93
Protein disulfide isomerase knockdown-induced cell death is cell-line-dependent and involves apoptosis in MCF-7 cells. J Toxicol Sci (2011) 0.92
NFE2L2 gene mutation in male Japanese squamous cell carcinoma of the lung. J Thorac Oncol (2010) 0.91
Epstein-Barr virus-related lymphoproliferative disorder, cytomegalovirus reactivation, and varicella zoster virus encephalitis during treatment of medulloblastoma. J Med Virol (2011) 0.90
Potent estrogenic metabolites of bisphenol A and bisphenol B formed by rat liver S9 fraction: their structures and estrogenic potency. Toxicol Sci (2003) 0.89
Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis. Life Sci (2004) 0.89
Fibroblast growth factor receptor 4 mutation and polymorphism in Japanese lung cancer. Oncol Rep (2008) 0.88
Braf and erbB2 mutations correlate with smoking status in lung cancer patients. Exp Ther Med (2012) 0.87
Activation of AMP-activated protein kinase by tributyltin induces neuronal cell death. Toxicol Appl Pharmacol (2008) 0.87
Pediatric primary leptomeningeal lymphoma treated without cranial radiotherapy. Pediatr Blood Cancer (2007) 0.87
Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer. Lung Cancer (2008) 0.87
Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons. Toxicol Sci (2005) 0.87
Adverse events of pulmonary vascular stapling in thoracic surgery. Interact Cardiovasc Thorac Surg (2013) 0.87
Neuroprotective or neurotoxic activity of 1-methyl-1,2,3,4-tetrahydroisoquinoline and related compounds. Bioorg Med Chem Lett (2003) 0.87
Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo. Arch Toxicol (2007) 0.87
Ipso substitution of bisphenol A catalyzed by microsomal cytochrome P450 and enhancement of estrogenic activity. Toxicol Lett (2011) 0.86
Prognostic factors of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children: report of the Japan Histiocytosis Study Group. Pediatr Blood Cancer (2014) 0.85
RET expression and detection of KIF5B/RET gene rearrangements in Japanese lung cancer. Cancer Med (2012) 0.85
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver. Drug Metab Dispos (2011) 0.85
Limb-girdle muscular dystrophy due to emerin gene mutations. Arch Neurol (2007) 0.85
Preparative monohydroxyflavanone syntheses and a protocol for gas chromatography-mass spectrometry analysis of monohydroxyflavanones. Chem Pharm Bull (Tokyo) (2005) 0.84
Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells. Biochem Biophys Res Commun (2013) 0.84
Improved high-performance liquid chromatographic detection of paclitaxel in patient's plasma using solid-phase extraction, and semi-micro-bore C18 separation and UV detection. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.84
Malignant rhabdoid tumor shows a unique neural differentiation as distinct from neuroblastoma. Cancer Sci (2003) 0.84
[Longer working hours of pharmacists in the ward resulted in lower medication-related errors--survey of national university hospitals in Japan]. Yakugaku Zasshi (2011) 0.83
DDR2 polymorphisms and mRNA expression in lung cancers of Japanese patients. Oncol Lett (2012) 0.83
The synthesis and structure-activity relationship of substituted N-phenyl anthranilic acid analogs as amyloid aggregation inhibitors. Bioorg Med Chem Lett (2008) 0.83
Expression of pericyte, mesangium and muscle markers in malignant rhabdoid tumor cell lines: differentiation-induction using 5-azacytidine. Cancer Sci (2003) 0.83
CHRNA5 gene D398N polymorphism in Japanese lung adenocarcinoma. J Surg Res (2009) 0.83
Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver. Drug Metab Dispos (2008) 0.83
1-Benzyl-1,2,3,4-tetrahydroisoquinoline binds with tubulin beta, a substrate of parkin, and reduces its polyubiquitination. J Neurochem (2010) 0.82
Involvement of autophagy via mammalian target of rapamycin (mTOR) inhibition in tributyltin-induced neuronal cell death. J Toxicol Sci (2010) 0.82
Geographic isolates of atypical Parkinsonism and tauopathy in the tropics: possible synergy of neurotoxins. Mov Disord (2006) 0.82
Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin. Drug Metab Dispos (2005) 0.82
Estrogenic activity of styrene oligomers after metabolic activation by rat liver microsomes. Environ Health Perspect (2003) 0.82
The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolysis products in rats. Toxicology (2007) 0.82
Concentration dependence of the mechanisms of tributyltin-induced apoptosis. Toxicol Sci (2007) 0.82
Approach for in vivo protein binding of 5-n-butyl-pyrazolo[1,5-a]pyrimidine bioactivated in chimeric mice with humanized liver by two-dimensional electrophoresis with accelerator mass spectrometry. Chem Res Toxicol (2010) 0.82
Usefulness of immunohistochemistry for the detection of the BRAF V600E mutation in Japanese lung adenocarcinoma. Lung Cancer (2013) 0.82
Design and synthesis of androgen receptor full antagonists bearing a p-carborane cage: promising ligands for anti-androgen withdrawal syndrome. J Med Chem (2010) 0.82
HRD1 levels increased by zonisamide prevented cell death and caspase-3 activation caused by endoplasmic reticulum stress in SH-SY5Y cells. J Mol Neurosci (2011) 0.81
Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor α and β and androgen receptor. Food Chem Toxicol (2013) 0.81
Hemophagocytic lymphohistiocytosis after hematopoietic stem cell transplantation in children: a nationwide survey in Japan. Pediatr Blood Cancer (2011) 0.81
A patient with Kawasaki disease who developed acute urinary retention due to pelvic neuroblastoma. Eur J Pediatr (2002) 0.81
Metabolism of the alpha,beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites. Drug Metab Dispos (2005) 0.81
Identification of rat prostatic secreted proteins using mass spectrometric analysis and androgen-dependent mRNA expression. J Androl (2009) 0.81
Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes. Drug Metab Dispos (2012) 0.81
A new class of androgen receptor antagonists bearing carborane in place of a steroidal skeleton. Bioorg Med Chem Lett (2005) 0.81
Expression of neural stem cell markers in malignant rhabdoid tumor cell lines. Oncol Rep (2010) 0.81
A nationwide survey of newly diagnosed childhood idiopathic thrombocytopenic purpura in Japan. J Pediatr Hematol Oncol (2009) 0.81
Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes. Bioorg Med Chem (2005) 0.81
Genotype analysis of the NRF2 gene mutation in lung cancer. Int J Mol Med (2013) 0.80
Thymoma with dissemination: efficacy of macroscopic total resection of disseminated nodules. World J Surg (2009) 0.80
[Tetrahydroisoquinoline derivatives as possible Parkinson's disease-inducing substances]. Yakugaku Zasshi (2002) 0.80
Minimal residual disease in early phase of chemotherapy reflects poor outcome in children with acute lymphoblastic leukemia--a retrospective study by the Children's Cancer and Leukemia Study Group in Japan. Leuk Lymphoma (2002) 0.80
Long-term exposure to endogenous levels of tributyltin decreases GluR2 expression and increases neuronal vulnerability to glutamate. Toxicol Appl Pharmacol (2009) 0.80
Antiandrogenic activity and metabolism of the organophosphorus pesticide fenthion and related compounds. Environ Health Perspect (2003) 0.80
Parkinsonism-preventing activity of 1-methyl-1,2,3,4-tetrahydroisoquinoline derivatives in C57BL mouse in vivo. Biol Pharm Bull (2006) 0.79
Synthesis and pharmacological profile of serofendic acids A and B. Bioorg Med Chem (2007) 0.79
Metal complexes with superoxide dismutase-like activity as candidates for anti-prion drug. Bioorg Med Chem Lett (2006) 0.79
TRAIL/Apo2L ligands induce apoptosis in malignant rhabdoid tumor cell lines. Pediatr Res (2003) 0.79
Annonamine, a new aporphine alkaloid from the leaves of Annona muricata. Chem Pharm Bull (Tokyo) (2012) 0.79
Keap1 mutations in lung cancer patients. Oncol Lett (2013) 0.79
Effect of tea beverages on aldehyde oxidase activity. Drug Metab Pharmacokinet (2010) 0.79
Detection of landiolol using high-performance liquid chromatography/fluorescence: a blood esterase-sensitive ultra-short-acting beta(1)-receptor antagonist. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.79
Estrogenic activity of an environmental pollutant, 2-nitrofluorene, after metabolic activation by rat liver microsomes. Biochem Biophys Res Commun (2003) 0.79
Potent estrogen receptor ligands based on bisphenols with a globular hydrophobic core. J Med Chem (2005) 0.79
A novel EGFR mutation D1012H and polymorphism at exon 25 in Japanese lung cancer. J Cancer Res Clin Oncol (2008) 0.79
Structure-activity relationships of 44 halogenated compounds for iodotyrosine deiodinase-inhibitory activity. Toxicology (2013) 0.79
High level of apoptosis and low AKT activation in mass screening as opposed to standard neuroblastoma. Histopathology (2010) 0.79