Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.
|
Nat Med
|
2004
|
22.96
|
2
|
Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy.
|
J Immunother
|
2002
|
2.65
|
3
|
Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.
|
J Clin Oncol
|
2011
|
2.52
|
4
|
Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers.
|
Clin Cancer Res
|
2011
|
2.44
|
5
|
Defining the critical hurdles in cancer immunotherapy.
|
J Transl Med
|
2011
|
2.32
|
6
|
Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT.
|
BMC Immunol
|
2005
|
2.31
|
7
|
Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation.
|
J Clin Oncol
|
2009
|
1.98
|
8
|
A systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers".
|
J Transl Med
|
2008
|
1.77
|
9
|
Immunoediting of cancers may lead to epithelial to mesenchymal transition.
|
J Immunol
|
2006
|
1.65
|
10
|
Precision and linearity targets for validation of an IFNgamma ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides.
|
BMC Immunol
|
2008
|
1.60
|
11
|
Humoral immunity directed against tumor-associated antigens as potential biomarkers for the early diagnosis of cancer.
|
J Proteome Res
|
2008
|
1.59
|
12
|
Immuno-oncology biomarkers 2010 and beyond: perspectives from the iSBTc/SITC biomarker task force.
|
J Transl Med
|
2010
|
1.57
|
13
|
IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice.
|
J Immunol
|
2006
|
1.53
|
14
|
Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity.
|
Clin Cancer Res
|
2002
|
1.51
|
15
|
Neu antigen-negative variants can be generated after neu-specific antibody therapy in neu transgenic mice.
|
Cancer Res
|
2004
|
1.49
|
16
|
CD4 regulatory T cells in human cancer pathogenesis.
|
Cancer Immunol Immunother
|
2006
|
1.47
|
17
|
Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology.
|
J Transl Med
|
2009
|
1.31
|
18
|
Antibody immunity to the p53 oncogenic protein is a prognostic indicator in ovarian cancer.
|
J Clin Oncol
|
2006
|
1.31
|
19
|
TNM staging in colorectal cancer: T is for T cell and M is for memory.
|
J Clin Oncol
|
2011
|
1.30
|
20
|
Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.
|
J Immunol
|
2010
|
1.26
|
21
|
VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.
|
Clin Cancer Res
|
2011
|
1.25
|
22
|
Insulin-like growth factor-binding protein-2 is a target for the immunomodulation of breast cancer.
|
Cancer Res
|
2008
|
1.24
|
23
|
The tumor antigen repertoire identified in tumor-bearing neu transgenic mice predicts human tumor antigens.
|
Cancer Res
|
2006
|
1.22
|
24
|
The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity.
|
Blood
|
2007
|
1.21
|
25
|
Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells.
|
Clin Cancer Res
|
2010
|
1.20
|
26
|
Immunization of cancer patients with HER-2/neu-derived peptides demonstrating high-affinity binding to multiple class II alleles.
|
Clin Cancer Res
|
2003
|
1.19
|
27
|
Level of HER-2/neu protein expression in breast cancer may affect the development of endogenous HER-2/neu-specific immunity.
|
Mol Cancer Ther
|
2008
|
1.15
|
28
|
Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera.
|
Cancer Prev Res (Phila)
|
2012
|
1.15
|
29
|
Endogenous anti-HER2 antibodies block HER2 phosphorylation and signaling through extracellular signal-regulated kinase.
|
Cancer Res
|
2005
|
1.14
|
30
|
Chitosan-alginate 3D scaffolds as a mimic of the glioma tumor microenvironment.
|
Biomaterials
|
2010
|
1.14
|
31
|
Functional T cell responses to tumor antigens in breast cancer patients have a distinct phenotype and cytokine signature.
|
J Immunol
|
2007
|
1.14
|
32
|
Adoptive transfer of tumor-primed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response.
|
Blood
|
2007
|
1.14
|
33
|
Tumor cells transduced with the MHC class II Transactivator and CD80 activate tumor-specific CD4+ T cells whether or not they are silenced for invariant chain.
|
Cancer Res
|
2006
|
1.04
|
34
|
ELISpot for measuring human immune responses to vaccines.
|
Expert Rev Vaccines
|
2011
|
1.04
|
35
|
Conflicts of interest in translational research.
|
J Transl Med
|
2004
|
1.03
|
36
|
Targeting of primary breast cancers and metastases in a transgenic mouse model using rationally designed multifunctional SPIONs.
|
ACS Nano
|
2012
|
1.03
|
37
|
SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: online resources and useful tools - a compass in the land of biomarker discovery.
|
J Transl Med
|
2011
|
1.02
|
38
|
Tumor antigen-specific T-cell expansion is greatly facilitated by in vivo priming.
|
Clin Cancer Res
|
2007
|
1.01
|
39
|
TLR2 agonist PSK activates human NK cells and enhances the antitumor effect of HER2-targeted monoclonal antibody therapy.
|
Clin Cancer Res
|
2011
|
1.00
|
40
|
Translational Research Working Group developmental pathway for immune response modifiers.
|
Clin Cancer Res
|
2008
|
1.00
|
41
|
HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase.
|
Cancer Immunol Immunother
|
2010
|
0.99
|
42
|
Human tumor cell lysates as a protein source for the detection of cancer antigen-specific humoral immunity.
|
J Immunol Methods
|
2005
|
0.95
|
43
|
Emergence of immune escape variant of mammary tumors that has distinct proteomic profile and a reduced ability to induce "danger signals".
|
Breast Cancer Res Treat
|
2005
|
0.95
|
44
|
Immune system versus tumor: shifting the balance in favor of DCs and effective immunity.
|
J Clin Invest
|
2004
|
0.95
|
45
|
Expanding assessments of translational research programs: supplementing metrics with value judgments.
|
Eval Health Prof
|
2013
|
0.94
|
46
|
Kinetics of tumor-specific T-cell response development after active immunization in patients with HER-2/neu overexpressing cancers.
|
Clin Immunol
|
2007
|
0.93
|
47
|
The invisible arm of immunity in common cancer chemoprevention agents.
|
Cancer Prev Res (Phila)
|
2013
|
0.92
|
48
|
Phenotype and in vitro function of mature MDDC generated from cryopreserved PBMC of cancer patients are equivalent to those from healthy donors.
|
J Immune Based Ther Vaccines
|
2007
|
0.91
|
49
|
Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immunosuppressive cells.
|
Clin Cancer Res
|
2012
|
0.91
|
50
|
Adoptive T cell therapy of solid cancers.
|
Cancer Immunol Immunother
|
2005
|
0.89
|
51
|
Direct detection of carcinoembryonic antigen autoantibodies in clinical human serum samples using a surface plasmon resonance sensor.
|
Colloids Surf B Biointerfaces
|
2008
|
0.89
|
52
|
Identification of tumor-specific antibodies in patients with breast cancer vaccinated with gene-modified allogeneic tumor cells.
|
J Immunother
|
2003
|
0.89
|
53
|
Immunologic principles and immunotherapeutic approaches in ovarian cancer.
|
Hematol Oncol Clin North Am
|
2003
|
0.89
|
54
|
Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions.
|
Cancer Prev Res (Phila)
|
2013
|
0.88
|
55
|
Pilot study of an HLA-A2 peptide vaccine using flt3 ligand as a systemic vaccine adjuvant.
|
J Clin Immunol
|
2003
|
0.88
|
56
|
An analytical workflow for investigating cytokine profiles.
|
Cytometry A
|
2008
|
0.87
|
57
|
Targeting serum antibody for cancer diagnosis: a focus on colorectal cancer.
|
Expert Opin Ther Targets
|
2007
|
0.86
|
58
|
Altered promoter usage characterizes monoallelic transcription arising with ERBB2 amplification in human breast cancers.
|
Genes Chromosomes Cancer
|
2006
|
0.85
|
59
|
Adoptive T-cell therapy for the treatment of solid tumours.
|
Expert Opin Biol Ther
|
2002
|
0.85
|
60
|
Phase I studies of drug combinations.
|
J Clin Oncol
|
2010
|
0.85
|
61
|
An HLA-DR-degenerate epitope pool detects insulin-like growth factor binding protein 2-specific immunity in patients with cancer.
|
Cancer Res
|
2008
|
0.85
|
62
|
Tumor stromal barriers to the success of adoptive T cell therapy.
|
Cancer Immunol Immunother
|
2007
|
0.84
|
63
|
Three-dimensional scaffolds to evaluate tumor associated fibroblast-mediated suppression of breast tumor specific T cells.
|
Biomacromolecules
|
2013
|
0.84
|
64
|
Therapeutic cancer vaccines and translating vaccinomics science to the global health clinic: emerging applications toward proof of concept.
|
OMICS
|
2011
|
0.83
|
65
|
Expression of HLA-DP0401 molecules for identification of DP0401 restricted antigen specific T cells.
|
J Clin Immunol
|
2005
|
0.83
|
66
|
T-helper I immunity, specific for the breast cancer antigen insulin-like growth factor-I receptor (IGF-IR), is associated with increased adiposity.
|
Breast Cancer Res Treat
|
2013
|
0.83
|
67
|
His-tag ELISA for the detection of humoral tumor-specific immunity.
|
BMC Immunol
|
2008
|
0.83
|
68
|
A degenerate HLA-DR epitope pool of HER-2/neu reveals a novel in vivo immunodominant epitope, HER-2/neu88-102.
|
Clin Cancer Res
|
2010
|
0.82
|
69
|
Common adjuvant breast cancer therapies do not inhibit cancer vaccine induced T cell immunity.
|
Breast Cancer Res Treat
|
2008
|
0.81
|
70
|
Protein-bound polysaccharide activates dendritic cells and enhances OVA-specific T cell response as vaccine adjuvant.
|
Immunobiology
|
2013
|
0.81
|
71
|
Cancer vaccines: the role of tumor burden in tipping the scale toward vaccine efficacy.
|
J Clin Oncol
|
2005
|
0.81
|
72
|
Fatal Bacillus cereus sepsis following resolving neutropenic enterocolitis during the treatment of acute leukemia.
|
Am J Hematol
|
2003
|
0.81
|
73
|
Global role of the immune system in identifying cancer initiation and limiting disease progression.
|
J Clin Oncol
|
2005
|
0.80
|
74
|
Antimetastatic gene expression profiles mediated by retinoic acid receptor beta 2 in MDA-MB-435 breast cancer cells.
|
BMC Cancer
|
2005
|
0.80
|
75
|
Identification of immunologic biomarkers associated with clinical response after immune-based therapy for cancer.
|
Ann N Y Acad Sci
|
2009
|
0.80
|
76
|
Sensitivity and specificity of tritiated thymidine incorporation and ELISPOT assays in identifying antigen specific T cell immune responses.
|
BMC Immunol
|
2007
|
0.79
|
77
|
Vaccination with ErbB-2 peptides prevents cancer stem cell expansion and suppresses the development of spontaneous tumors in MMTV-PyMT transgenic mice.
|
Breast Cancer Res Treat
|
2014
|
0.79
|
78
|
CCL21 and IFNγ recruit and activate tumor specific T cells in 3D scaffold model of breast cancer.
|
Anticancer Agents Med Chem
|
2014
|
0.79
|
79
|
Immune modulation as a therapeutic strategy for non-small-cell lung cancer.
|
Clin Lung Cancer
|
2008
|
0.78
|
80
|
Clonal diversity of the T-cell population responding to a dominant HLA-A2 epitope of HER-2/neu after active immunization in an ovarian cancer patient.
|
Hum Immunol
|
2002
|
0.78
|
81
|
Therapeutic vaccines for ovarian cancer.
|
Gynecol Oncol
|
2013
|
0.78
|
82
|
Clinical studies of vaccines targeting breast cancer.
|
Clin Cancer Res
|
2003
|
0.78
|
83
|
Antitumor efficacy of CD137 ligation is maximized by the use of a CD137 single-chain Fv-expressing whole-cell tumor vaccine compared with CD137-specific monoclonal antibody infusion.
|
Mol Cancer Ther
|
2006
|
0.77
|
84
|
Identification of a broad coverage HLA-DR degenerate epitope pool derived from carcinoembryonic antigen.
|
Cancer Immunol Immunother
|
2009
|
0.77
|
85
|
Designing vaccines to prevent breast cancer recurrence or invasive disease.
|
Immunotherapy
|
2015
|
0.76
|
86
|
Values in translation: how asking the right questions can move translational science toward greater health impact.
|
Clin Transl Sci
|
2012
|
0.76
|
87
|
Proteomic profiling of the autoimmune response to breast cancer antigens uncovers a suppressive effect of hormone therapy.
|
Proteomics Clin Appl
|
2013
|
0.76
|
88
|
Natural history of tumor growth and immune modulation in common spontaneous murine mammary tumor models.
|
Breast Cancer Res Treat
|
2014
|
0.76
|
89
|
Molecular targeting with cancer vaccines.
|
J Clin Oncol
|
2005
|
0.76
|
90
|
Adjuvant Oophorectomy in the Treatment of Early-Stage BRCA Mutation-Positive Breast Cancer.
|
JAMA Oncol
|
2015
|
0.75
|
91
|
Gamma delta T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK.
|
Cancer Immunol Immunother
|
2013
|
0.75
|
92
|
Underlying Autoimmune Disease Is Not a Contraindication to the Use of Ipilimumab.
|
JAMA Oncol
|
2016
|
0.75
|
93
|
Delayed type hypersensitivity response to recall antigens does not accurately reflect immune competence in advanced stage breast cancer patients.
|
Breast Cancer Res Treat
|
2002
|
0.75
|
94
|
Immunotherapy of glioblastoma multiforme.
|
Expert Rev Neurother
|
2003
|
0.75
|
95
|
Immunotherapy for breast cancer.
|
Cancer Chemother Biol Response Modif
|
2002
|
0.75
|
96
|
10th Biennial Helene Harris Memorial Trust meeting.
|
Cancer Res
|
2006
|
0.75
|