Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU.
|
EMBO J
|
2003
|
3.10
|
2
|
Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis.
|
Endocrinology
|
2004
|
2.50
|
3
|
Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress.
|
Neuropsychopharmacology
|
2005
|
2.24
|
4
|
Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains.
|
J Neurosci
|
2003
|
2.04
|
5
|
Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling.
|
J Pharmacol Exp Ther
|
2006
|
1.93
|
6
|
Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli.
|
J Neurochem
|
2005
|
1.78
|
7
|
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling.
|
J Pharmacol Exp Ther
|
2009
|
1.74
|
8
|
Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling.
|
Eur J Neurosci
|
2005
|
1.70
|
9
|
Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells.
|
Nat Med
|
2007
|
1.69
|
10
|
The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity.
|
J Lipid Res
|
2004
|
1.52
|
11
|
Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice.
|
Neuropharmacology
|
2007
|
1.51
|
12
|
Endogenous cannabinoid signaling is essential for stress adaptation.
|
Proc Natl Acad Sci U S A
|
2010
|
1.49
|
13
|
Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis.
|
Neuropsychopharmacology
|
2009
|
1.47
|
14
|
Fast feedback inhibition of the HPA axis by glucocorticoids is mediated by endocannabinoid signaling.
|
Endocrinology
|
2010
|
1.46
|
15
|
Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression.
|
Proc Natl Acad Sci U S A
|
2006
|
1.41
|
16
|
Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism.
|
Mol Pharmacol
|
2004
|
1.40
|
17
|
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response.
|
J Neurosci
|
2011
|
1.37
|
18
|
Spatial correlations of laminar BOLD and CBV responses to rat whisker stimulation with neuronal activity localized by Fos expression.
|
Magn Reson Med
|
2004
|
1.35
|
19
|
Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid.
|
J Pharmacol Exp Ther
|
2008
|
1.35
|
20
|
2-arachidonoylglycerol: a novel inhibitor of androgen-independent prostate cancer cell invasion.
|
Cancer Res
|
2004
|
1.30
|
21
|
Endocannabinoid signaling mediates cocaine-induced inhibitory synaptic plasticity in midbrain dopamine neurons.
|
J Neurosci
|
2008
|
1.29
|
22
|
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress.
|
Psychoneuroendocrinology
|
2009
|
1.27
|
23
|
Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders.
|
Neurosci Biobehav Rev
|
2008
|
1.27
|
24
|
Adaptations in endocannabinoid signaling in response to repeated homotypic stress: a novel mechanism for stress habituation.
|
Eur J Neurosci
|
2008
|
1.25
|
25
|
Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity.
|
J Pharmacol Exp Ther
|
2003
|
1.25
|
26
|
Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide.
|
J Biol Chem
|
2004
|
1.24
|
27
|
Characterization of phospholipase activity of the Pseudomonas aeruginosa type III cytotoxin, ExoU.
|
J Bacteriol
|
2005
|
1.23
|
28
|
The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase.
|
Br J Pharmacol
|
2003
|
1.22
|
29
|
Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala.
|
Neuropsychopharmacology
|
2005
|
1.21
|
30
|
Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis.
|
J Neurosci
|
2007
|
1.21
|
31
|
Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition.
|
Am J Physiol Heart Circ Physiol
|
2003
|
1.20
|
32
|
Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment.
|
J Neurochem
|
2008
|
1.18
|
33
|
Rapid elevations in limbic endocannabinoid content by glucocorticoid hormones in vivo.
|
Psychoneuroendocrinology
|
2010
|
1.14
|
34
|
Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain.
|
J Physiol
|
2004
|
1.13
|
35
|
The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants.
|
Trends Pharmacol Sci
|
2009
|
1.10
|
36
|
Estrogenic regulation of limbic cannabinoid receptor binding.
|
Psychoneuroendocrinology
|
2010
|
1.10
|
37
|
D2 dopamine receptor activation facilitates endocannabinoid-mediated long-term synaptic depression of GABAergic synaptic transmission in midbrain dopamine neurons via cAMP-protein kinase A signaling.
|
J Neurosci
|
2008
|
1.09
|
38
|
Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus.
|
Hippocampus
|
2008
|
1.08
|
39
|
Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries.
|
Am J Physiol Heart Circ Physiol
|
2004
|
1.08
|
40
|
1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide.
|
Biochem J
|
2003
|
1.08
|
41
|
Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model.
|
Free Radic Biol Med
|
2010
|
1.07
|
42
|
Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress.
|
Cereb Cortex
|
2011
|
1.07
|
43
|
Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress.
|
Neuropsychopharmacology
|
2010
|
1.06
|
44
|
Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells.
|
Blood
|
2005
|
1.05
|
45
|
Endocannabinoid signalling: has it got rhythm?
|
Br J Pharmacol
|
2010
|
1.04
|
46
|
Involvement of the endocannabinoid system in the ability of long-term tricyclic antidepressant treatment to suppress stress-induced activation of the hypothalamic-pituitary-adrenal axis.
|
Neuropsychopharmacology
|
2006
|
1.04
|
47
|
Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus.
|
Hippocampus
|
2010
|
1.03
|
48
|
Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans.
|
Neuropsychopharmacology
|
2012
|
1.00
|
49
|
Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks.
|
Psychoneuroendocrinology
|
2013
|
1.00
|
50
|
Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor.
|
Invest Ophthalmol Vis Sci
|
2008
|
0.99
|
51
|
1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide.
|
J Biol Chem
|
2004
|
0.97
|
52
|
Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation.
|
J Psychopharmacol
|
2011
|
0.97
|
53
|
Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway.
|
Eur Neuropsychopharmacol
|
2012
|
0.97
|
54
|
Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta.
|
Arterioscler Thromb Vasc Biol
|
2005
|
0.96
|
55
|
Microinjection of a cannabinoid receptor antagonist into the NTS increases baroreflex duration in dogs.
|
Am J Physiol Heart Circ Physiol
|
2003
|
0.95
|
56
|
Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: role of 5HT(1A) and CB2 receptors.
|
Neuropharmacology
|
2013
|
0.95
|
57
|
Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior.
|
Proc Natl Acad Sci U S A
|
2010
|
0.95
|
58
|
Effects of endocannabinoids on discharge of baroreceptive NTS neurons.
|
Neurosci Lett
|
2005
|
0.93
|
59
|
Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death.
|
J Biol Chem
|
2005
|
0.93
|
60
|
Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index.
|
Pharmacogenomics
|
2008
|
0.91
|
61
|
Chronic corticosterone treatment increases the endocannabinoid 2-arachidonylglycerol in the rat amygdala.
|
Eur J Pharmacol
|
2005
|
0.90
|
62
|
Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease.
|
Free Radic Biol Med
|
2009
|
0.90
|
63
|
Interactions between endocannabinoids and stress-induced decreased sensitivity to natural reward.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2006
|
0.90
|
64
|
U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevance.
|
Am J Physiol Heart Circ Physiol
|
2005
|
0.87
|
65
|
Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation.
|
Free Radic Biol Med
|
2005
|
0.86
|
66
|
Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent.
|
Pharmacogenomics
|
2009
|
0.86
|
67
|
Brain uptake and utilization of fatty acids, lipids and lipoproteins: application to neurological disorders.
|
J Mol Neurosci
|
2007
|
0.86
|
68
|
Cannabinoid-induced Fos expression within A10 dopaminergic neurons.
|
Brain Res
|
2003
|
0.85
|
69
|
Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period.
|
Synapse
|
2012
|
0.85
|
70
|
1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3.
|
J Neurochem
|
2003
|
0.84
|
71
|
Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents.
|
J Neural Transm (Vienna)
|
2008
|
0.83
|
72
|
Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity.
|
J Neurochem
|
2007
|
0.83
|
73
|
Retrograde release of endocannabinoids inhibits presynaptic GABA release to second-order baroreceptive neurons in NTS.
|
Auton Neurosci
|
2010
|
0.82
|
74
|
Inhibition of fatty acid amide hydrolase suppresses referred hyperalgesia induced by bladder inflammation.
|
BJU Int
|
2010
|
0.81
|
75
|
Natural and synthetic corticosteroids inhibit uptake 2-mediated transport in CNS neurons.
|
Physiol Behav
|
2010
|
0.81
|
76
|
Hemisynthesis and preliminary evaluation of novel endocannabinoid analogues.
|
Bioorg Med Chem Lett
|
2003
|
0.81
|
77
|
Endocannabinoid signaling in the etiology and treatment of major depressive illness.
|
Curr Pharm Des
|
2014
|
0.80
|
78
|
Serum contents of endocannabinoids are correlated with blood pressure in depressed women.
|
Lipids Health Dis
|
2012
|
0.80
|
79
|
Attenuation of cystitis and pain sensation in mice lacking fatty acid amide hydrolase.
|
J Mol Neurosci
|
2014
|
0.78
|
80
|
Brain region-specific changes in N-acylethanolamine contents with time of day.
|
J Neurochem
|
2013
|
0.78
|
81
|
The CB1 receptor antagonist SR141716 enhances stimulus-induced activation of the primary somatosensory cortex of the rat.
|
Neurosci Lett
|
2002
|
0.78
|
82
|
Role of endocannabinoid signaling in anxiety and depression.
|
Curr Top Behav Neurosci
|
2009
|
0.77
|
83
|
Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research.
|
J Mol Neurosci
|
2007
|
0.77
|
84
|
Sterol carrier protein-2: binding protein for endocannabinoids.
|
Mol Neurobiol
|
2014
|
0.76
|
85
|
Circulating endocannabinoid concentrations and sexual arousal in women.
|
J Sex Med
|
2012
|
0.75
|
86
|
Production of hydroxyeicosatetraenoic acids and prostaglandins by a novel rat microglial cell line.
|
J Neuroimmunol
|
2004
|
0.75
|
87
|
Waterborne lead exposure affects brain endocannabinoid content in male but not female fathead minnows (Pimephales promelas).
|
Neurotoxicology
|
2005
|
0.75
|
88
|
Chronic administration of nitric oxide reduces angiotensin II receptor type 1 expression and aldosterone synthesis in zona glomerulosa cells.
|
Am J Physiol Endocrinol Metab
|
2004
|
0.75
|
89
|
Endocannabinoid and Mood Responses to Exercise in Adults with Varying Activity Levels.
|
Med Sci Sports Exerc
|
2017
|
0.75
|
90
|
Endocannabinoid Responses To Exercise In Low, Moderate, And High Active Individuals: 3765 Board #204 June 4, 8: 00 AM - 9: 30 AM.
|
Med Sci Sports Exerc
|
2016
|
0.75
|