Yves Engelborghs

Author PubWeight™ 74.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. J Biol Chem 2002 4.91
2 LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells. J Biol Chem 2003 3.97
3 The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding. J Biol Chem 2005 2.28
4 The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis. J Biol Chem 2007 1.89
5 Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication. J Virol 2006 1.82
6 Fluorescence lifetime standards for time and frequency domain fluorescence spectroscopy. Anal Chem 2007 1.74
7 Rational design of photoconvertible and biphotochromic fluorescent proteins for advanced microscopy applications. Chem Biol 2011 1.64
8 Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations. J Virol 2003 1.54
9 Dark states in monomeric red fluorescent proteins studied by fluorescence correlation and single molecule spectroscopy. Biophys J 2008 1.52
10 Stretched exponential decay and correlations in the catalytic activity of fluctuating single lipase molecules. Proc Natl Acad Sci U S A 2005 1.51
11 Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75. J Biol Chem 2004 1.47
12 Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV. PLoS Pathog 2007 1.41
13 Correct diffusion coefficients of proteins in fluorescence correlation spectroscopy. Application to tubulin oligomers induced by Mg2+ and Paclitaxel. Biophys J 2004 1.36
14 Human immunoglobulin adsorption investigated by means of quartz crystal microbalance dissipation, atomic force microscopy, surface acoustic wave, and surface plasmon resonance techniques. Langmuir 2004 1.32
15 Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A. J Biol Chem 2003 1.21
16 Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand. J Biol Chem 2005 1.18
17 Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes. Eur J Biochem 2002 1.15
18 Single-enzyme kinetics of CALB-catalyzed hydrolysis. Angew Chem Int Ed Engl 2005 1.15
19 Early aggregation steps in alpha-synuclein as measured by FCS and FRET: evidence for a contagious conformational change. Biophys J 2010 1.14
20 The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase. J Biol Chem 2005 1.11
21 Role of quorum sensing and antimicrobial component production by Serratia plymuthica in formation of biofilms, including mixed biofilms with Escherichia coli. Appl Environ Microbiol 2006 1.11
22 The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering. Nucleic Acids Res 2010 1.08
23 Probing diffusion laws within cellular membranes by Z-scan fluorescence correlation spectroscopy. Biophys J 2006 1.07
24 Fast and reversible photoswitching of the fluorescent protein dronpa as evidenced by fluorescence correlation spectroscopy. Biophys J 2006 1.04
25 Measuring diffusion of lipid-like probes in artificial and natural membranes by raster image correlation spectroscopy (RICS): use of a commercial laser-scanning microscope with analog detection. Langmuir 2009 1.00
26 Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology. J Neurosci 2010 1.00
27 Measuring protein-protein interactions inside living cells using single color fluorescence correlation spectroscopy. Application to human immunodeficiency virus type 1 integrase and LEDGF/p75. FASEB J 2005 1.00
28 The high-affinity peptidoglycan binding domain of Pseudomonas phage endolysin KZ144. Biochem Biophys Res Commun 2009 0.99
29 Biliverdin reductase is a transporter of haem into the nucleus and is essential for regulation of HO-1 gene expression by haematin. Biochem J 2008 0.98
30 Microtubule binding and clustering of human Tau-4R and Tau-P301L proteins isolated from yeast deficient in orthologues of glycogen synthase kinase-3beta or cdk5. J Biol Chem 2006 0.94
31 The conformation and the aggregation kinetics of α-synuclein depend on the proline residues in its C-terminal region. Biochemistry 2010 0.94
32 The dead-end elimination method, tryptophan rotamers, and fluorescence lifetimes. Biophys J 2003 0.93
33 Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein. Peptides 2008 0.93
34 Visualization of membrane rafts using a perylene monoimide derivative and fluorescence lifetime imaging. Biophys J 2007 0.92
35 A fast and sensitive method for measuring the integrity of siRNA-carrier complexes in full human serum. J Control Release 2007 0.90
36 The aggregation of alpha-synuclein is stimulated by FK506 binding proteins as shown by fluorescence correlation spectroscopy. FASEB J 2006 0.88
37 DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy. J Biol Chem 2002 0.88
38 Diffusion of myelin oligodendrocyte glycoprotein in living OLN-93 cells investigated by raster-scanning image correlation spectroscopy (RICS). J Fluoresc 2008 0.87
39 FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T. J Neurochem 2008 0.85
40 Association with coregulators is the major determinant governing peroxisome proliferator-activated receptor mobility in living cells. J Biol Chem 2006 0.84
41 Experimental indication for the existence of multiple Trp rotamers in von Willebrand Factor A3 domain. Proteins 2004 0.84
42 Both substrate hydrolysis and secondary substrate binding determine xylanase mobility as assessed by FRAP. J Phys Chem B 2011 0.83
43 Tryptophan rotamers as evidenced by X-ray, fluorescence lifetimes, and molecular dynamics modeling. Biophys J 2006 0.82
44 Enzymatic investigation of the Staphylococcus aureus type I signal peptidase SpsB - implications for the search for novel antibiotics. FEBS J 2009 0.82
45 Conformational states of the switch I region of Ha-ras-p21 in hinge residue mutants studied by fluorescence lifetime and fluorescence anisotropy measurements. Protein Sci 2003 0.81
46 Structural characterisation of the hepatitis C envelope glycoprotein E1 ectodomain derived from a mammalian and a yeast expression system. Vaccine 2007 0.80
47 Synergistic antifungal activity of two chitin-binding proteins from spindle tree (Euonymus europaeus L.). Planta 2004 0.80
48 Integrating nuclear receptor mobility in models of gene regulation. Nucl Recept Signal 2006 0.79
49 Tryptophan properties in fluorescence and functional stability of plasminogen activator inhibitor 1. Biophys J 2003 0.79
50 Solution structure and internal dynamics of NSCP, a compact calcium-binding protein. FEBS J 2005 0.79
51 Fluorescence correlation spectroscopy analysis of the dynamics of tubulin interaction with RB3, a stathmin family protein. FEBS Lett 2003 0.79
52 A fluorescence stopped-flow kinetic study of the conformational activation of alpha-chymotrypsin and several mutants. Protein Sci 2004 0.78
53 How do rotameric conformations influence the time-resolved fluorescence of tryptophan in proteins? A perspective based on molecular modeling and quantum chemistry. Curr Protein Pept Sci 2008 0.78
54 Diffusion of sphingomyelin and myelin oligodendrocyte glycoprotein in the membrane of OLN-93 oligodendroglial cells studied by fluorescence correlation spectroscopy. C R Biol 2005 0.78
55 SAP-like domain in nucleolar spindle associated protein mediates mitotic chromosome loading as well as interphase chromatin interaction. Biochem Biophys Res Commun 2011 0.78
56 Exploration of the activation pathway of Deltaalpha-Chymotrypsin with molecular dynamics simulations and correlation with kinetic experiments. Eur Biophys J 2008 0.77
57 An unusual red-edge excitation and time-dependent Stokes shift in the single tryptophan mutant protein DD-carboxypeptidase from Streptomyces: the role of dynamics and tryptophan rotamers. Protein Sci 2007 0.77
58 Fluorescence correlation spectroscopy to determine the diffusion coefficient of α-synuclein and follow early oligomer formation. Methods Mol Biol 2012 0.76
59 Physical requirements for in vitro processing of the Streptomyces lividans signal peptidases. J Biotechnol 2002 0.76
60 The characterization of the nuclear dynamics of syntenin-2, a PIP2 binding PDZ protein. Cytometry A 2013 0.76
61 Tryptophan conformations associated with partial unfolding in ribonuclease T1. Biophys J 2009 0.76
62 Protein simulations: the absorption spectrum of barnase point mutants. Protein Sci 2004 0.76
63 Mammalian ribosomal and chaperone protein RPS3A counteracts α-synuclein aggregation and toxicity in a yeast model system. Biochem J 2013 0.76
64 Mechanism of fluorescence and conformational changes of the sarcoplasmic calcium binding protein of the sand worm Nereis diversicolor upon Ca2+ or Mg2+ binding. Biophys J 2003 0.75
65 Simulation of the activation of alpha-chymotrypsin: analysis of the pathway and role of the propeptide. Protein Sci 2004 0.75
66 Solvent-controlled organization of self-assembled polymeric monolayers on gold: an easy approach for the construction of protein resistant surfaces. Langmuir 2005 0.75
67 Fluorescence lifetime measurements of intrinsically unstructured proteins: application to α-synuclein. Methods Mol Biol 2012 0.75
68 Tryptophan side chain conformers monitored by NMR and time-resolved fluorescence spectroscopies. Proteins 2011 0.75