Published in Biophys J on February 04, 2005
Ceramide-rich platforms in transmembrane signaling. FEBS Lett (2010) 1.46
Absence of fluid-ordered/fluid-disordered phase coexistence in ceramide/POPC mixtures containing cholesterol. Biophys J (2006) 1.36
Detergent-resistant, ceramide-enriched domains in sphingomyelin/ceramide bilayers. Biophys J (2005) 1.30
Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. J Clin Invest (2012) 1.25
Domain formation and stability in complex lipid bilayers as reported by cholestatrienol. Biophys J (2005) 1.08
Lipid raft composition modulates sphingomyelinase activity and ceramide-induced membrane physical alterations. Biophys J (2009) 1.04
Ceramide and mitochondria in ischemia/reperfusion. J Cardiovasc Pharmacol (2009) 1.04
Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis. J Biol Chem (2010) 1.01
Membrane organization and ionization behavior of the minor but crucial lipid ceramide-1-phosphate. Biophys J (2008) 0.99
Coexistence of immiscible mixtures of palmitoylsphingomyelin and palmitoylceramide in monolayers and bilayers. Biophys J (2009) 0.98
The permeability enhancing mechanism of DMSO in ceramide bilayers simulated by molecular dynamics. Biophys J (2007) 0.96
Cholesterol displaces palmitoylceramide from its tight packing with palmitoylsphingomyelin in the absence of a liquid-disordered phase. Biophys J (2010) 0.90
Mixing properties of sphingomyelin ceramide bilayers: a simulation study. J Phys Chem B (2012) 0.88
Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties. J Biol Chem (2013) 0.87
The lifetime of UDP-galactose:ceramide galactosyltransferase is controlled by a distinct endoplasmic reticulum-associated degradation (ERAD) regulated by sigma-1 receptor chaperones. J Biol Chem (2012) 0.84
Ceramide acyl chain length markedly influences miscibility with palmitoyl sphingomyelin in bilayer membranes. Eur Biophys J (2009) 0.80
Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain. J Lipid Res (2013) 0.80
Importance of the sphingoid base length for the membrane properties of ceramides. Biophys J (2012) 0.79
Sphingosine-1-phosphate as an amphipathic metabolite: its properties in aqueous and membrane environments. Biophys J (2009) 0.78
Effects of sphingomyelin headgroup size on interactions with ceramide. Biophys J (2013) 0.78
The Long-Chain Sphingoid Base of Ceramides Determines Their Propensity for Lateral Segregation. Biophys J (2017) 0.76
Influence of Hydroxylation, Chain Length, and Chain Unsaturation on Bilayer Properties of Ceramides. Biophys J (2015) 0.76
Sphingolipids and mitochondrial apoptosis. J Bioenerg Biomembr (2016) 0.76
Effects of lipid interactions on model vesicle engulfment by alveolar macrophages. Biophys J (2014) 0.76
Ultrasound Microbubble Treatment Enhances Clathrin-Mediated Endocytosis and Fluid-Phase Uptake through Distinct Mechanisms. PLoS One (2016) 0.75
Ceramide-C16 Is a Versatile Modulator of Phosphatidylethanolamine Polymorphism. Biophys J (2017) 0.75
PLGA/liposome hybrid nanoparticles for short-chain ceramide delivery. Pharm Res (2013) 0.75
Elastic properties of lipid bilayers: theory and possible experiments. Z Naturforsch C (1974) 19.89
Physical principles of membrane organization. Q Rev Biophys (1980) 5.02
Molecular arrangements in sphingolipids. Conformation and hydrogen bonding of ceramide and their implication on membrane stability and permeability. Biochim Biophys Acta (1976) 2.06
Ceramide: second messenger or modulator of membrane structure and dynamics? Biochem J (2003) 2.06
Compartmentalization of ceramide signaling: physical foundations and biological effects. J Cell Physiol (2000) 2.01
Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membrane. Biochemistry (1998) 2.00
The mechanism of lamellar-to-inverted hexagonal phase transitions in phosphatidylethanolamine: implications for membrane fusion mechanisms. Biophys J (1997) 1.95
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins. J Biol Chem (2002) 1.94
Role of sphingomyelinase and ceramide in modulating rafts: do biophysical properties determine biologic outcome? FEBS Lett (2002) 1.86
Diacylglycerols, lysolecithin, or hydrocarbons markedly alter the bilayer to hexagonal phase transition temperature of phosphatidylethanolamines. Biochemistry (1985) 1.79
The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis. J Biol Chem (2000) 1.73
Ceramides in phospholipid membranes: effects on bilayer stability and transition to nonlamellar phases. Biophys J (1999) 1.68
Lipid microdomains in dimyristoylphosphatidylcholine-ceramide liposomes. Chem Phys Lipids (1997) 1.64
Structural and thermotropic properties of synthetic C16:0 (palmitoyl) ceramide: effect of hydration. J Lipid Res (1995) 1.51
Ceramide interaction with the respiratory chain of heart mitochondria. Biochemistry (2000) 1.44
Different effects of enzyme-generated ceramides and diacylglycerols in phospholipid membrane fusion and leakage. J Biol Chem (1996) 1.36
The effect of ceramide on phosphatidylcholine membranes: a deuterium NMR study. Biophys J (2002) 1.28
Phase behavior and molecular interactions in mixtures of ceramide with dipalmitoylphosphatidylcholine. J Lipid Res (1999) 1.27
Membrane restructuring via ceramide results in enhanced solute efflux. J Biol Chem (2002) 1.24
Interaction of ceramides with phosphatidylcholine, sphingomyelin and sphingomyelin/cholesterol bilayers. Biochim Biophys Acta (2001) 1.21
Ceramide induces structural defects into phosphatidylcholine bilayers and activates phospholipase A2. Biochem Biophys Res Commun (1996) 1.19
Asymmetric addition of ceramides but not dihydroceramides promotes transbilayer (flip-flop) lipid motion in membranes. Biophys J (2004) 1.15
Vesicle membrane fusion induced by the concerted activities of sphingomyelinase and phospholipase C. J Biol Chem (1998) 1.07
Sphingomyelinase activity causes transbilayer lipid translocation in model and cell membranes. J Biol Chem (2003) 1.05
Thermodynamic, motional, and structural aspects of gramicidin-induced hexagonal HII phase formation in phosphatidylethanolamine. Biochemistry (1985) 1.01
Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides. Biochim Biophys Acta (2005) 0.99
Ceramides perturb the structure of phosphatidylcholine bilayers and modulate the activity of phospholipase A2. Eur Biophys J (1998) 0.97
Diacylglycerol and the promotion of lamellar-hexagonal and lamellar-isotropic phase transitions in lipids: implications for membrane fusion. Biophys J (1996) 0.97
Partial dehydration of phosphatidylethanolamine phosphate groups during hexagonal phase formation, as seen by i.r. spectroscopy. Biochem J (1992) 0.97
Lipid domains and orthorhombic phases in model stratum corneum: evidence from Fourier transform infrared spectroscopy studies. Biochem Biophys Res Commun (1997) 0.94
Lipid concentration affects the kinetic stability of dielaidoylphosphatidylethanolamine bilayers. Chem Phys Lipids (1993) 0.91
Sphingolipids. Annu Rev Biochem (1971) 0.85
Phase properties of mixtures of ceramides. Lipids (1995) 0.85
Ceramide modulates the lipid membrane organization at molecular and supramolecular levels. Chem Phys Lipids (2003) 0.84
Effect of long-chain acyl-CoAs and acylcarnitines on gel-fluid and lamellar-hexagonal phospholipid phase transitions. Mol Membr Biol (1997) 0.81
Gangliosides of extraneuronal tissue. Chem Phys Lipids (1970) 0.80
The influence of vitamin K1 on the structure and phase behaviour of model membrane systems. Biochim Biophys Acta (1999) 0.80
Use of sphingolipid analogs: benefits and risks. Biochim Biophys Acta (1999) 0.80
Effects of platelet-activating factor and related lipids on dielaidoylphosphatidylethanolamine by DSC, FTIR and NMR. Biochim Biophys Acta (1993) 0.79
Modulation of polymorphic properties of dielaidoylphosphatidylethanolamine by the antineoplastic ether lipid 1-O-octadecyl-2-O-methyl-glycero-3-phosphocholine. Biochim Biophys Acta (1999) 0.77
Detergent-resistant membranes should not be identified with membrane rafts. Trends Biochem Sci (2005) 2.62
Surgical menopause increases salt sensitivity of blood pressure. Hypertension (2006) 2.38
The octamer is the major form of CENP-A nucleosomes at human centromeres. Nat Struct Mol Biol (2013) 1.59
Sphingomyelinases: enzymology and membrane activity. FEBS Lett (2002) 1.49
Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids. Biochim Biophys Acta (2006) 1.44
Giant unilamellar vesicles electroformed from native membranes and organic lipid mixtures under physiological conditions. Biophys J (2007) 1.42
Membranes: a meeting point for lipids, proteins and therapies. J Cell Mol Med (2008) 1.37
Detergent-resistant, ceramide-enriched domains in sphingomyelin/ceramide bilayers. Biophys J (2005) 1.30
Effects of ceramide and other simple sphingolipids on membrane lateral structure. Biochim Biophys Acta (2008) 1.30
Phase diagrams of lipid mixtures relevant to the study of membrane rafts. Biochim Biophys Acta (2008) 1.29
Molecular mechanism of membrane permeabilization by the peptide antibiotic surfactin. Biochim Biophys Acta (2003) 1.25
Membrane restructuring via ceramide results in enhanced solute efflux. J Biol Chem (2002) 1.24
Lipid-protein interactions in GPCR-associated signaling. Biochim Biophys Acta (2006) 1.24
Transbilayer (flip-flop) lipid motion and lipid scrambling in membranes. FEBS Lett (2009) 1.16
Asymmetric addition of ceramides but not dihydroceramides promotes transbilayer (flip-flop) lipid motion in membranes. Biophys J (2004) 1.15
Independent centromere formation in a capricious, gene-free domain of chromosome 13q21 in Old World monkeys and pigs. Genome Biol (2006) 1.13
Membrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family. J Bacteriol (2004) 1.13
Modulation of PI-specific phospholipase C by membrane curvature and molecular order. Biochemistry (2005) 1.10
Cholesterol displacement by ceramide in sphingomyelin-containing liquid-ordered domains, and generation of gel regions in giant lipidic vesicles. FEBS Lett (2008) 1.08
Sphingomyelinase activity causes transbilayer lipid translocation in model and cell membranes. J Biol Chem (2003) 1.05
Formation of novel CENP-A domains on tandem repetitive DNA and across chromosome breakpoints on human chromosome 8q21 neocentromeres. Chromosoma (2011) 0.99
Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides. Biochim Biophys Acta (2005) 0.99
Membrane organization and ionization behavior of the minor but crucial lipid ceramide-1-phosphate. Biophys J (2008) 0.99
Coexistence of immiscible mixtures of palmitoylsphingomyelin and palmitoylceramide in monolayers and bilayers. Biophys J (2009) 0.98
Sphingosine increases the permeability of model and cell membranes. Biophys J (2006) 0.98
Leakage-free membrane fusion induced by the hydrolytic activity of PlcHR(2), a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa. Biochim Biophys Acta (2007) 0.97
Human cytomegalovirus: detection of congenital and perinatal infection in Argentina. BMC Pediatr (2004) 0.97
Domain formation in sphingomyelin/cholesterol mixed membranes studied by spin-label electron spin resonance spectroscopy. Biochemistry (2005) 0.97
Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold hemolysis. Biochemistry (2008) 0.94
Detergent solubilization of phosphatidylcholine bilayers in the fluid state: influence of the acyl chain structure. Biochim Biophys Acta (2006) 0.93
Dihydrosphingomyelin impairs HIV-1 infection by rigidifying liquid-ordered membrane domains. Chem Biol (2010) 0.91
Cholesterol displaces palmitoylceramide from its tight packing with palmitoylsphingomyelin in the absence of a liquid-disordered phase. Biophys J (2010) 0.90
TrwD, the hexameric traffic ATPase encoded by plasmid R388, induces membrane destabilization and hemifusion of lipid vesicles. J Bacteriol (2002) 0.90
Sphingomyelin organization is required for vesicle biogenesis at the Golgi complex. EMBO J (2012) 0.89
Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes. Biochemistry (2004) 0.89
Biophysics (and sociology) of ceramides. Biochem Soc Symp (2005) 0.89
The mechanism of detergent solubilization of lipid bilayers. Biophys J (2013) 0.89
The calcium-binding C-terminal domain of Escherichia coli alpha-hemolysin is a major determinant in the surface-active properties of the protein. J Biol Chem (2007) 0.89
Edelfosine is incorporated into rafts and alters their organization. J Phys Chem B (2008) 0.89
Sphingomyelinase cleavage of sphingomyelin in pure and mixed lipid membranes. Influence of the physical state of the sphingolipid. Chem Phys Lipids (2002) 0.89
Long-term renoprotective effects of standard versus high doses of telmisartan in hypertensive nondiabetic nephropathies. Am J Kidney Dis (2005) 0.89
Calcium-dependent conformational changes of membrane-bound Ebola fusion peptide drive vesicle fusion. FEBS Lett (2003) 0.87
New pH-sensitive liposomes containing phosphatidylethanolamine and a bacterial dirhamnolipid. Chem Phys Lipids (2010) 0.87
Phospholipases C and sphingomyelinases: Lipids as substrates and modulators of enzyme activity. Prog Lipid Res (2012) 0.86
Surface-active properties of the antitumour ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (edelfosine). Biochim Biophys Acta (2007) 0.86
Detergent effects on membranes at subsolubilizing concentrations: transmembrane lipid motion, bilayer permeabilization, and vesicle lysis/reassembly are independent phenomena. Langmuir (2010) 0.86
Aggregation behaviour of a dirhamnolipid biosurfactant secreted by Pseudomonas aeruginosa in aqueous media. J Colloid Interface Sci (2006) 0.86
Detergent solubilization of lipid bilayers: a balance of driving forces. Trends Biochem Sci (2013) 0.86
Implication of ceramide, ceramide 1-phosphate and sphingosine 1-phosphate in tumorigenesis. Transl Oncogenomics (2008) 0.86
Role of the transmembrane domain in the stability of TrwB, an integral protein involved in bacterial conjugation. J Biol Chem (2003) 0.85
Hemolytic activity of a bacterial trehalose lipid biosurfactant produced by Rhodococcus sp.: evidence for a colloid-osmotic mechanism. Langmuir (2010) 0.84
Binding of β-amyloid (1-42) peptide to negatively charged phospholipid membranes in the liquid-ordered state: modeling and experimental studies. Biophys J (2012) 0.84
Membrane insertion stabilizes the structure of TrwB, the R388 conjugative plasmid coupling protein. Biochim Biophys Acta (2011) 0.84
Multiple stages of detergent-erythrocyte membrane interaction--a spin label study. Biochim Biophys Acta (2010) 0.83
Interaction of phospholipases C and sphingomyelinase with liposomes. Methods Enzymol (2003) 0.83
Electroformation of giant unilamellar vesicles from native membranes and organic lipid mixtures for the study of lipid domains under physiological ionic-strength conditions. Methods Mol Biol (2010) 0.83
End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa. Biochim Biophys Acta (2009) 0.83
Lipid bilayers containing sphingomyelins and ceramides of varying N-acyl lengths: a glimpse into sphingolipid complexity. Biochim Biophys Acta (2013) 0.83
Rosemary (Rosmarinus officinalis) diterpenes affect lipid polymorphism and fluidity in phospholipid membranes. Arch Biochem Biophys (2006) 0.83
Mechanism of membrane permeabilization by a bacterial trehalose lipid biosurfactant produced by Rhodococcus sp. Langmuir (2009) 0.83
Imaging the early stages of phospholipase C/sphingomyelinase activity on vesicles containing coexisting ordered-disordered and gel-fluid domains. J Lipid Res (2011) 0.82
Methionine adenosyltransferase alpha-helix structure unfolds at lower temperatures than beta-sheet: a 2D-IR study. Biophys J (2004) 0.82
Surfactant effects of chlorpromazine and imipramine on lipid bilayers containing sphingomyelin and cholesterol. J Colloid Interface Sci (2002) 0.82
Lipid bilayers in the gel phase become saturated by triton X-100 at lower surfactant concentrations than those in the fluid phase. Biophys J (2012) 0.82
Thermodynamic and structural changes associated with the interaction of a dirhamnolipid biosurfactant with bovine serum albumin. Langmuir (2008) 0.82
Triton X-100 partitioning into sphingomyelin bilayers at subsolubilizing detergent concentrations: effect of lipid phase and a comparison with dipalmitoylphosphatidylcholine. Biophys J (2007) 0.82
Combination of the anti-tumour cell ether lipid edelfosine with sterols abolishes haemolytic side effects of the drug. J Chem Biol (2008) 0.82
Ceramide-induced transbilayer (flip-flop) lipid movement in membranes. Methods Mol Biol (2009) 0.81
Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes. Int J Pharm (2006) 0.81
The transmembrane domain provides nucleotide binding specificity to the bacterial conjugation protein TrwB. FEBS Lett (2006) 0.81
His-859 is an essential residue for the activity and pH dependence of Escherichia coli RTX toxin alpha-hemolysin. J Biol Chem (2002) 0.81
Cholesterol reverts Triton X-100 preferential solubilization of sphingomyelin over phosphatidylcholine: a 31P-NMR study. FEBS Lett (2009) 0.81