Published in J Exp Biol on February 01, 2005
Ketone bodies as signaling metabolites. Trends Endocrinol Metab (2013) 1.37
Oxidative stress and epigenetic regulation in ageing and age-related diseases. Int J Mol Sci (2013) 1.25
Aging and immune function: molecular mechanisms to interventions. Antioxid Redox Signal (2011) 1.18
Epigenetics, aging, and autoimmunity. Autoimmunity (2008) 1.11
Expression of hsp22 and hsp70 transgenes is partially predictive of drosophila survival under normal and stress conditions. J Gerontol A Biol Sci Med Sci (2009) 1.10
Heat shock proteins and Drosophila aging. Exp Gerontol (2010) 1.05
The role of epigenetics in aging and autoimmunity. Clin Rev Allergy Immunol (2010) 1.03
Between destiny and disease: genetics and molecular pathways of human central nervous system aging. Prog Neurobiol (2010) 1.03
Combined pharmacological induction of Hsp70 suppresses prion protein neurotoxicity in Drosophila. PLoS One (2014) 0.96
Involvement of redox state in the aging of Drosophila melanogaster. Antioxid Redox Signal (2013) 0.91
Stress proteins in aging and life span. Int J Hyperthermia (2013) 0.90
The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan. PLoS Genet (2008) 0.90
Gender-specific prandial response to dietary restriction and oxidative stress in Drosophila melanogaster. Fly (Austin) (2011) 0.88
The role of D-GADD45 in oxidative, thermal and genotoxic stress resistance. Cell Cycle (2012) 0.87
The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging. Aging Cell (2015) 0.86
Chemical regulation of mid- and late-life longevities in Drosophila. Exp Gerontol (2012) 0.85
Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells. J Biol Chem (2009) 0.85
Aging induced endoplasmic reticulum stress alters sleep and sleep homeostasis. Neurobiol Aging (2013) 0.85
SIN3 is critical for stress resistance and modulates adult lifespan. Aging (Albany NY) (2014) 0.83
Epigenetic drugs: a novel anti-aging strategy? Front Genet (2012) 0.82
RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity. Aging (Albany NY) (2015) 0.79
Overexpression of heat shock factor 1 inhibits butyrate-induced differentiation in colon cancer cells. Cell Stress Chaperones (2006) 0.79
Inhibition of histone deacetylase by butyrate protects rat liver from ischemic reperfusion injury. Int J Mol Sci (2014) 0.78
Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity. Oncotarget (2015) 0.78
Drosophila melanogaster Hsp22: a mitochondrial small heat shock protein influencing the aging process. Front Genet (2015) 0.78
Rpd3 interacts with insulin signaling in Drosophila longevity extension. Aging (Albany NY) (2016) 0.77
Regulation of genes related to immune signaling and detoxification in Apis mellifera by an inhibitor of histone deacetylation. Sci Rep (2017) 0.75
Loss of BOSS Causes Shortened Lifespan with Mitochondrial Dysfunction in Drosophila. PLoS One (2017) 0.75
PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila. Elife (2017) 0.75
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature (2005) 31.60
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med (2002) 23.42
Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet (2007) 15.46
Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet (2004) 8.60
Hypothalamic regulation of sleep and circadian rhythms. Nature (2005) 8.23
Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet (2009) 6.35
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science (2006) 5.67
Altered microRNA expression in human heart disease. Physiol Genomics (2007) 5.64
Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest (2005) 5.51
Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev (2009) 5.21
Sleep state switching. Neuron (2010) 4.94
The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes. Science (2012) 4.93
Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol Cell (2009) 4.71
Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium. Cell (2005) 4.51
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell (2002) 4.35
A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science (2007) 3.73
From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal (2007) 3.49
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology (2003) 3.19
The DNA sequence of human chromosome 7. Nature (2003) 3.18
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A (2008) 3.13
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A (2008) 3.10
Metamaterials application in sensing. Sensors (Basel) (2012) 3.09
CD99 plays a major role in the migration of monocytes through endothelial junctions. Nat Immunol (2002) 3.01
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc Natl Acad Sci U S A (2007) 3.00
The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells. Cell (2008) 2.94
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease. J Mol Cell Cardiol (2004) 2.90
Pathway level analysis of gene expression using singular value decomposition. BMC Bioinformatics (2005) 2.78
A broad role for melanopsin in nonvisual photoreception. J Neurosci (2003) 2.78
Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis. Nature (2003) 2.74
The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology (2011) 2.71
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. Nat Immunol (2008) 2.70
Highly prevalent TERT promoter mutations in aggressive thyroid cancers. Endocr Relat Cancer (2013) 2.69
Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev Cell (2009) 2.60
A preliminary report of penile transplantation. Eur Urol (2006) 2.54
Glutamate receptors: RNA editing and death of motor neurons. Nature (2004) 2.53
MicroRNA miR-125a controls hematopoietic stem cell number. Proc Natl Acad Sci U S A (2010) 2.53
The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models. Inflamm Bowel Dis (2014) 2.46
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell (2013) 2.43
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev (2009) 2.41
Genome-wide and organ-specific landscapes of epigenetic modifications and their relationships to mRNA and small RNA transcriptomes in maize. Plant Cell (2009) 2.39
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy. Nat Med (2003) 2.38
The Arabidopsis heterochronic gene ZIPPY is an ARGONAUTE family member. Curr Biol (2003) 2.31
Structure-function analysis of the bestrophin family of anion channels. J Biol Chem (2003) 2.30
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature (2005) 2.27
Differential rescue of light- and food-entrainable circadian rhythms. Science (2008) 2.20
MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol (2009) 2.18
Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci (2003) 2.15
Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization. Blood (2009) 2.11
Thioredoxin and thioredoxin reductase: current research with special reference to human disease. Biochem Biophys Res Commun (2010) 2.09
Gaussian Bare-Bones Differential Evolution. IEEE Trans Cybern (2013) 2.08
Activation of STAT6 by STING is critical for antiviral innate immunity. Cell (2011) 2.08
Streptococcus suis sequence type 7 outbreak, Sichuan, China. Emerg Infect Dis (2006) 2.07
PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. Nat Immunol (2009) 2.07
The DNA sequence and analysis of human chromosome 14. Nature (2003) 2.02
Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol (2007) 2.00
Roads to polyploidy: the megakaryocyte example. J Cell Physiol (2002) 2.00
The hypothalamic integrator for circadian rhythms. Trends Neurosci (2005) 1.99
The genomes of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also signatures of common ancestry. PLoS Genet (2012) 1.95
Reassessment of the structural basis of the ascending arousal system. J Comp Neurol (2011) 1.93
RNA catalyses nuclear pre-mRNA splicing. Nature (2013) 1.86
Afferents to the ventrolateral preoptic nucleus. J Neurosci (2002) 1.86
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? EMBO J (2005) 1.86
Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice. Gastroenterology (2010) 1.85
Immunophenotypic analysis of AIDS-related diffuse large B-cell lymphoma and clinical implications in patients from AIDS Malignancies Consortium clinical trials 010 and 034. J Clin Oncol (2009) 1.84
Sequence and comparative analysis of the maize NB mitochondrial genome. Plant Physiol (2004) 1.83
Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii. PLoS One (2009) 1.83
New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes. Genesis (2002) 1.80
Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus. Chem Biol (2011) 1.80
Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics. Sci Transl Med (2012) 1.80
Three-column fixation for complex tibial plateau fractures. J Orthop Trauma (2010) 1.73
A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc Natl Acad Sci U S A (2003) 1.69
A minimal domain responsible for Munc13 activity. Nat Struct Mol Biol (2005) 1.68
Two-dimensional nanocrystals produced by exfoliation of Ti3 AlC2. Adv Mater (2011) 1.66
Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microglia. J Biol Chem (2012) 1.66
Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity. J Biol Chem (2005) 1.64
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell (2012) 1.61
A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. Genome Biol (2008) 1.60
Characteristics and smoking patterns of intermittent smokers. Exp Clin Psychopharmacol (2012) 1.59
Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat Struct Mol Biol (2010) 1.58
The relationship between PTH and 25-hydroxy vitamin D early in pregnancy. Clin Endocrinol (Oxf) (2011) 1.56
Retracted Predicting new molecular targets for rhein using network pharmacology. BMC Syst Biol (2012) 1.55
Human multipotent stromal cells from bone marrow and microRNA: regulation of differentiation and leukemia inhibitory factor expression. Proc Natl Acad Sci U S A (2008) 1.54
Comparisons among two fertile and three male-sterile mitochondrial genomes of maize. Genetics (2007) 1.53
TERT promoter mutations and their association with BRAF V600E mutation and aggressive clinicopathological characteristics of thyroid cancer. J Clin Endocrinol Metab (2014) 1.52
Modern analytical techniques in metabolomics analysis. Analyst (2011) 1.52
Identification of a new Neisseria meningitidis serogroup C clone from Anhui province, China. Lancet (2006) 1.50
SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression. Cancer Res (2012) 1.50
A hierarchical model for estimating response time distributions. Psychon Bull Rev (2005) 1.50
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nat Commun (2012) 1.49
The effect of repeated etomidate anesthesia on adrenocortical function during a course of electroconvulsive therapy. J ECT (2011) 1.49
Exogenous surfactant may improve oxygenation but not mortality in adult patients with acute lung injury/acute respiratory distress syndrome: a meta-analysis of 9 clinical trials. J Cardiothorac Vasc Anesth (2012) 1.47
InGaAs/AlGaAsSb avalanche photodiode with high gain-bandwidth product. Opt Express (2016) 1.46
The effect of dipeptidyl peptidase-IV inhibition on bone in a mouse model of type 2 diabetes. Diabetes Metab Res Rev (2014) 1.45
Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity. J Biol Chem (2008) 1.45
Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones. Endocrinology (2006) 1.44
Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. Ann Thorac Surg (2007) 1.44
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat Commun (2013) 1.43
Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia. Proc Natl Acad Sci U S A (2010) 1.43