PubRank

M Wajner

Author PubWeight™ 47.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inborn errors of metabolism. Sensitivity of screening tests in high risk patients. Clin Pediatr (Phila) 1989 1.38
2 Methylmalonate inhibits succinate-supported oxygen consumption by interfering with mitochondrial succinate uptake. J Inherit Metab Dis 2008 1.13
3 Evidence for oxidative stress in tissues derived from succinate semialdehyde dehydrogenase-deficient mice. J Inherit Metab Dis 2007 1.06
4 Selective screening of 10,000 high-risk Brazilian patients for the detection of inborn errors of metabolism. Eur J Pediatr 1997 0.99
5 Inhibition of the mitochondrial respiratory chain complex activities in rat cerebral cortex by methylmalonic acid. Neurochem Int 2002 0.92
6 Evidence that oxidative stress is increased in patients with X-linked adrenoleukodystrophy. Biochim Biophys Acta 2004 0.92
7 Reduction of large neutral amino acid levels in plasma and brain of hyperleucinemic rats. Neurochem Int 2001 0.92
8 Oxidative stress in patients with phenylketonuria. Biochim Biophys Acta 2005 0.85
9 Pharmacological evidence for GABAergic and glutamatergic involvement in the convulsant and behavioral effects of glutaric acid. Brain Res 1998 0.85
10 Propionic and L-methylmalonic acids induce oxidative stress in brain of young rats. Neuroreport 2000 0.85
11 Evidence that L-carnitine and selenium supplementation reduces oxidative stress in phenylketonuric patients. Cell Mol Neurobiol 2010 0.85
12 Effect of chemically induced propionic acidemia on neurobehavioral development of rats. Pharmacol Biochem Behav 1999 0.84
13 Inhibition of mitochondrial creatine kinase activity from rat cerebral cortex by methylmalonic acid. Neurochem Int 2004 0.84
14 3-hydroxyglutaric acid enhances glutamate uptake into astrocytes from cerebral cortex of young rats. Neurochem Int 2004 0.83
15 Effects of methylmalonic and propionic acids on glutamate uptake by synaptosomes and synaptic vesicles and on glutamate release by synaptosomes from cerebral cortex of rats. Brain Res 2001 0.82
16 Detection of metabolic disorders in high-risk patients. A pilot study in Salvador, Bahia. Arq Neuropsiquiatr 1997 0.82
17 Intrastriatal methylmalonic acid administration induces rotational behavior and convulsions through glutamatergic mechanisms. Brain Res 1996 0.82
18 Na+, K+ ATPase activity is markedly reduced by cis-4-decenoic acid in synaptic plasma membranes from cerebral cortex of rats. Exp Neurol 2005 0.82
19 Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain. Braz J Med Biol Res 2001 0.82
20 [Application of a clinical and laboratory protocol for the investigation of inborn errors of metabolism among critically ill children] J Pediatr (Rio J) 2003 0.82
21 Intrastriatal administration of 3-hydroxyglutaric acid induces convulsions and striatal lesions in rats. Brain Res 2001 0.82
22 Inhibition of succinate dehydrogenase and beta-hydroxybutyrate dehydrogenase activities by methylmalonate in brain and liver of developing rats. J Inherit Metab Dis 1993 0.81
23 Methylmalonate administration decreases Na+,K+-ATPase activity in cerebral cortex of rats. Neuroreport 2000 0.81
24 Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease. J Neurol Sci 2000 0.81
25 Inhibition of rat brain Na+, K+-ATPase activity induced by homocysteine is probably mediated by oxidative stress. Neurochem Res 2001 0.81
26 In vitro inhibition of Na+,K(+)-ATPase activity from rat cerebral cortex by guanidino compounds accumulating in hyperargininemia. Brain Res 1999 0.81
27 Alanine reverses the inhibitory effect of phenylalanine and its metabolites on Na+,K(+)-ATPase in synaptic plasma membranes from cerebral cortex of rats. Biochem Soc Trans 1995 0.80
28 Inhibition of mitogen and allogeneic stimulated lymphocyte growth by human amniotic fluid: lack of correlation between alpha-fetoprotein level and in vitro immunosuppression. Eur J Obstet Gynecol Reprod Biol 1986 0.80
29 3-Hydroxyglutaric acid moderately impairs energy metabolism in brain of young rats. Neuroscience 2005 0.80
30 Effect of hyperprolinemia on acetylcholinesterase and butyrylcholinesterase activities in rat. Amino Acids 2005 0.80
31 D-2-hydroxyglutaric acid inhibits creatine kinase activity from cardiac and skeletal muscle of young rats. Eur J Clin Invest 2003 0.80
32 Neurochemical effects of L-pyroglutamic acid. Neurochem Res 1995 0.80
33 Promotion of oxidative stress by 3-hydroxyglutaric acid in rat striatum. J Inherit Metab Dis 2005 0.80
34 Animal models for glutaryl-CoA dehydrogenase deficiency. J Inherit Metab Dis 2004 0.79
35 Inhibition of energy metabolism by 2-methylacetoacetate and 2-methyl-3-hydroxybutyrate in cerebral cortex of developing rats. J Inherit Metab Dis 2005 0.79
36 L-pyroglutamic acid inhibits energy production and lipid synthesis in cerebral cortex of young rats in vitro. Neurochem Res 2001 0.79
37 Quinolinic acid inhibits glutamate uptake into synaptic vesicles from rat brain. Neuroreport 2000 0.79
38 Nitric oxide synthase inhibition by L-NAME prevents the decrease of Na+,K+-ATPase activity in midbrain of rats subjected to arginine administration. Neurochem Res 2001 0.79
39 Reduced locomotor activity of rats made histidinemic by injection of histidine. J Nutr 1989 0.79
40 Inhibition of energy production in vitro by glutaric acid in cerebral cortex of young rats. Metab Brain Dis 2000 0.79
41 Ascorbic acid and alpha-tocopherol attenuate methylmalonic acid-induced convulsions. Neuroreport 1999 0.79
42 Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats. Biochem Med Metab Biol 1991 0.78
43 The influence of amino acids on mitogen-activated proliferation of human lymphocytes in vitro. Int J Immunopharmacol 1994 0.78
44 In vitro stimulation of oxidative stress in cerebral cortex of rats by the guanidino compounds accumulating in hyperargininemia. Brain Res 2001 0.78
45 Inhibition of lymphocyte transformation by serum from pregnant women: lack of correlation with levels of alpha-fetoprotein. Biol Neonate 1983 0.78
46 Inhibition of in-vitro lymphocyte transformation by the isoquinoline alkaloid berberine. J Pharm Pharmacol 1995 0.78
47 Seven-year experience of a reference laboratory for detection of inborn errors of metabolism in Brazil. J Inherit Metab Dis 1991 0.78
48 Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res 2001 0.78
49 Creatine protects against the convulsive behavior and lactate production elicited by the intrastriatal injection of methylmalonate. Neuroscience 2003 0.77
50 Inhibition of rat brain lipid synthesis in vitro by 4-hydroxybutyric acid. Metab Brain Dis 1999 0.77
51 Redox homeostasis is compromised in vivo by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency in rat cerebral cortex and liver. Free Radic Res 2013 0.77
52 The influence of organic acids on the proliferation of human peripheral lymphocytes activated by concanavalin A and pokeweed mitogen. Int J Immunopharmacol 1996 0.77
53 Oxidative stress in phenylketonuric patients. Mol Genet Metab 2011 0.77
54 Platelet Na+, K+-ATPase activity as a possible peripheral marker for the neurotoxic effects of phenylalanine in phenylketonuria. Metab Brain Dis 2000 0.77
55 Inhibition of citrate oxidation in vitro by 2-hydroxybutyrate and 4-hydroxybutyrate in cerebral cortex of young rats. Biochem Soc Trans 1995 0.77
56 Effects of histidine and imidazolelactic acid on various parameters of the oxidative stress in cerebral cortex of young rats. Int J Dev Neurosci 2004 0.76
57 Isolated 3-methylcrotonyl-coenzyme A carboxylase deficiency in a child with metabolic stroke. J Inherit Metab Dis 2006 0.76
58 2-Hydroxybutyrate and 4-hydroxybutyrate inhibit CO2 formation from labeled substrates by rat cerebral cortex. Biochem Soc Trans 1995 0.76
59 Clinical and biochemical effects of long-term vitamin A administration to a patient with Hurler-Scheie compound. Braz J Med Biol Res 1984 0.76
60 Reduction of plasma concentrations of large neutral amino acids in patients with maple syrup urine disease during crises. Arch Dis Child 1999 0.76
61 Inhibition of Na+,K+-ATPase from rat brain cortex by propionic acid. Neuroreport 1998 0.76
62 Inhibition of synaptosomal [3H]glutamate uptake and [3H]glutamate binding to plasma membranes from brain of young rats by glutaric acid in vitro. J Neurol Sci 2000 0.76
63 Investigation of oxidative stress parameters in treated phenylketonuric patients. Metab Brain Dis 2006 0.76
64 Chronic early leucine administration induces behavioral deficits in rats. Life Sci 1999 0.75
65 Response of human peripheral blood lymphocytes in the presence of cord sera: relationship of lymphocyte transformation with number of pregnancies and levels of alpha-fetoprotein. Clin Exp Immunol 1983 0.75
66 Cytoskeleton as a potential target in the neuropathology of maple syrup urine disease: insight from animal studies. J Inherit Metab Dis 2007 0.75
67 An improved specific laboratory test for homocystinuria. Clin Chim Acta 1982 0.75
68 Proline administration decreases Na+,K+-ATPase activity in the synaptic plasma membrane from cerebral cortex of rats. Metab Brain Dis 1999 0.75
69 Reduced Na(+), K(+)-ATPase activity in erythrocyte membranes from patients with phenylketonuria. Pediatr Res 2001 0.75
70 Detection of inborn errors of metabolism in unselected patients from pediatric intensive care units in Porto Alegre, Brazil: evaluation of screening techniques. Braz J Med Biol Res 1987 0.75
71 Effects of acute and chronic administration of methylmalonic and propionic acids on the in vitro incorporation of 32P into cytoskeletal proteins from cerebral cortex of young rats. Neurochem Int 1998 0.75
72 Creatine prevents behavioral alterations caused by methylmalonic acid administration into the hippocampus of rats in the open field task. J Neurol Sci 2006 0.75
73 Influence of methylmalonate on the uptake of ketone bodies in vitro by the brain of young rats. Biochem Soc Trans 1990 0.75
74 Inhibition of phytohaemagglutinin-induced lymphocyte blastogenesis by serum from pregnant women: correlation between cortisol level and in vitro immunosuppression. Acta Endocrinol (Copenh) 1985 0.75
75 Effect of phenylalanine and its metabolites on ATP diphosphohydrolase activity in synaptosomes from rat cerebral cortex. Neurochem Res 1994 0.75
76 Inhibition of Na+,K+-ATPase activity from rat hippocampus by proline. Neurochem Res 2001 0.75
77 Effects of methylmalonate and propionate on [3H]glutamate binding, adenylate cyclase activity and lipid synthesis in rat cerebral cortex. Biochem Mol Biol Int 1997 0.75
78 Relationship between some obstetric landmarks and the concentration of alpha-fetoprotein in maternal blood. J Perinat Med 1986 0.75
79 The influence of aldosterone on the phytohemagglutinin-induced human lymphocyte blastogenesis. Rev Bras Biol 1985 0.75
80 Tay-Sachs disease heterozygote detection in Brazil: comparison between tears and leukocytes as beta-hexosaminidase A source. J Inherit Metab Dis 1984 0.75
81 The effect of organic acids on phytohaemagglutinin-activated proliferation of human lymphocytes in vitro. Int J Immunopharmacol 1995 0.75
82 Alanine prevents the decrease of Na+,K+-ATPase activity in experimental phenylketonuria. Metab Brain Dis 1999 0.75
83 Effect of propionic and methylmalonic acids on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex. Neurochem Res 2002 0.75
84 Methylmalonic acid reduces the in vitro phosphorylation of cytoskeletal proteins in the cerebral cortex of rats. Brain Res 1997 0.75
85 In vitro phosphorylation of cytoskeletal proteins in the rat cerebral cortex is decreased by propionic acid. Exp Neurol 1997 0.75
86 Effect of postnatal methylmalonate administration on adult rat behavior. Braz J Med Biol Res 1991 0.75
87 Effects of postnatal methylmalonate administration on neurobehavioral development of rats. Braz J Med Biol Res 1994 0.75
88 Propionic and methylmalonic acids inhibit the in vitro phosphorylation of a 85 kDa cytoskeletal protein from cerebral cortex of rats. Neurochem Int 1998 0.75
89 Alpha-ketoisocaproate increases the in vitro 32P incorporation into intermediate filaments in cerebral cortex of rats. Neuroreport 2000 0.75
90 Chronic administration of propionic acid reduces ganglioside N-acetylneuraminic acid concentration in cerebellum of young rats. J Neurol Sci 1998 0.75
91 Methylmalonic and propionic acids increase the in vitro incorporation of 32P into cytoskeletal proteins from cerebral cortex of young rats through NMDA glutamate receptors. Brain Res 2000 0.75
92 Disruption of redox homeostasis and brain damage caused in vivo by methylmalonic acid and ammonia in cerebral cortex and striatum of developing rats. Free Radic Res 2014 0.75
93 Immunomodulatory action of amino acids on lymphocyte blastogenesis. Biochem Soc Trans 1992 0.75
94 Effect of the branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex. Metab Brain Dis 2002 0.75
95 Effect of phenylalanine, p-chlorophenylalanine and alpha-methylphenylalanine on glucose uptake in vitro by the brain of young rats. Biochem Soc Trans 1990 0.75
96 Chronic postnatal administration of methylmalonic acid provokes a decrease of myelin content and ganglioside N-acetylneuraminic acid concentration in cerebrum of young rats. Braz J Med Biol Res 2001 0.75
97 Incidence of 3-hydroxy-3-methylglutaryl-coenzyme A lyase (HL) deficiency in Brazil, South America. J Inherit Metab Dis 2007 0.75
98 ATP diphosphohydrolase activity in synaptosomes from cerebral cortex of rats subjected to chemically induced phenylketonuria. Braz J Med Biol Res 1995 0.75
99 Effect of proline administration on rat behavior in aversive and nonaversive tasks. Pharmacol Biochem Behav 1989 0.75
100 Inhibition of glutamate uptake into synaptic vesicles from rat brain by 3-nitropropionic acid in vitro. Exp Neurol 2001 0.75