S C Kozma

Author PubWeight™ 61.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Drosophila S6 kinase: a regulator of cell size. Science 1999 6.76
2 Phosphorylation and activation of p70s6k by PDK1. Science 1998 6.53
3 Mammalian TOR: a homeostatic ATP sensor. Science 2001 6.41
4 Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. EMBO J 1998 5.34
5 The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. EMBO J 1995 4.26
6 Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family. Proc Natl Acad Sci U S A 1994 4.16
7 Activation of p70/p85 S6 kinase by a pathway independent of p21ras. Nature 1994 3.67
8 Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice. Nature 2001 3.65
9 Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6. Science 2000 3.07
10 The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases. Mol Cell Biol 1996 2.28
11 The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sites. J Biol Chem 1993 1.91
12 Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation. J Biol Chem 1998 1.64
13 Dual requirement for a newly identified phosphorylation site in p70s6k. Mol Cell Biol 1997 1.63
14 A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation. Proc Natl Acad Sci U S A 1992 1.58
15 The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231. Nucleic Acids Res 1987 1.49
16 Identification and early activation of a Xenopus laevis p70s6k following progesterone-induced meiotic maturation. EMBO J 1992 1.45
17 The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity. Proc Natl Acad Sci U S A 1996 1.33
18 New acceptor cell for transfected genomic DNA: oncogene transfer into a mouse mammary epithelial cell line. Mol Cell Biol 1985 1.26
19 A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo. Mol Cell Biol 1998 1.22
20 p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis. Mol Cell Biol 1999 1.14
21 Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin. Biochem J 2000 0.97
22 cDNA sequence of the human ribosomal large subunit protein L7a. Nucleic Acids Res 1988 0.90