1
|
Drosophila S6 kinase: a regulator of cell size.
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Science
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1999
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6.76
|
2
|
Phosphorylation and activation of p70s6k by PDK1.
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Science
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1998
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6.53
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3
|
Mammalian TOR: a homeostatic ATP sensor.
|
Science
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2001
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6.41
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4
|
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.
|
EMBO J
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1998
|
5.34
|
5
|
The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.
|
EMBO J
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1995
|
4.26
|
6
|
Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family.
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Proc Natl Acad Sci U S A
|
1994
|
4.16
|
7
|
Activation of p70/p85 S6 kinase by a pathway independent of p21ras.
|
Nature
|
1994
|
3.67
|
8
|
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.
|
Nature
|
2001
|
3.65
|
9
|
Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6.
|
Science
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2000
|
3.07
|
10
|
The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases.
|
Mol Cell Biol
|
1996
|
2.28
|
11
|
The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sites.
|
J Biol Chem
|
1993
|
1.91
|
12
|
Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation.
|
J Biol Chem
|
1998
|
1.64
|
13
|
Dual requirement for a newly identified phosphorylation site in p70s6k.
|
Mol Cell Biol
|
1997
|
1.63
|
14
|
A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation.
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Proc Natl Acad Sci U S A
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1992
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1.58
|
15
|
The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231.
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Nucleic Acids Res
|
1987
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1.49
|
16
|
Identification and early activation of a Xenopus laevis p70s6k following progesterone-induced meiotic maturation.
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EMBO J
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1992
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1.45
|
17
|
The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity.
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Proc Natl Acad Sci U S A
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1996
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1.33
|
18
|
New acceptor cell for transfected genomic DNA: oncogene transfer into a mouse mammary epithelial cell line.
|
Mol Cell Biol
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1985
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1.26
|
19
|
A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo.
|
Mol Cell Biol
|
1998
|
1.22
|
20
|
p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis.
|
Mol Cell Biol
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1999
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1.14
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21
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Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin.
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Biochem J
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2000
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0.97
|
22
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cDNA sequence of the human ribosomal large subunit protein L7a.
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Nucleic Acids Res
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1988
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0.90
|