Published in Dev Dyn on March 01, 2005
H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state. PLoS Biol (2007) 3.18
Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets. Mol Cell Biol (2006) 2.99
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev (2007) 2.57
Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes. EMBO J (2007) 2.49
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J (2010) 2.11
The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation. PLoS Genet (2006) 2.08
p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nat Struct Mol Biol (2007) 2.03
Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia. Blood (2009) 1.90
The N terminus of Drosophila ESC binds directly to histone H3 and is required for E(Z)-dependent trimethylation of H3 lysine 27. Mol Cell Biol (2007) 1.60
The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis. Epigenetics Chromatin (2009) 1.59
Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2. Mol Biol Cell (2007) 1.48
Polycomb-group proteins repress the floral activator AGL19 in the FLC-independent vernalization pathway. Genes Dev (2006) 1.41
Molecular integration of wingless, decapentaplegic, and autoregulatory inputs into Distalless during Drosophila leg development. Dev Cell (2008) 1.40
Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice. Dev Biol (2009) 1.30
Functional and cancer genomics of ASXL family members. Br J Cancer (2013) 1.21
Polycomb group protein Suppressor 2 of zeste is a functional homolog of Posterior Sex Combs. Mol Cell Biol (2008) 1.03
The Epc-N domain: a predicted protein-protein interaction domain found in select chromatin associated proteins. BMC Genomics (2006) 0.98
Telomeric position effect--a third silencing mechanism in eukaryotes. PLoS One (2008) 0.95
Role of chromatin states in transcriptional memory. Biochim Biophys Acta (2009) 0.94
Differential expression of genes involved in the epigenetic regulation of cell identity in normal human mammary cell commitment and differentiation. Chin J Cancer (2014) 0.89
Turning on myogenin in muscle: a paradigm for understanding mechanisms of tissue-specific gene expression. Comp Funct Genomics (2012) 0.89
The enhancer of trithorax and polycomb corto interacts with cyclin G in Drosophila. PLoS One (2008) 0.87
Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1. BMC Mol Biol (2007) 0.85
Molecular genetic analysis of Suppressor 2 of zeste identifies key functional domains. Genetics (2009) 0.85
Corto and DSP1 interact and bind to a maintenance element of the Scr Hox gene: understanding the role of Enhancers of trithorax and Polycomb. BMC Biol (2006) 0.83
Functional characterization of the dRYBP gene in Drosophila. Genetics (2008) 0.82
Molecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fish. Genet Sel Evol (2014) 0.81
Feature-based classification of amino acid substitutions outside conserved functional protein domains. ScientificWorldJournal (2013) 0.77
The role of maintenance proteins in the preservation of epithelial cell identity during mammary gland remodeling and breast cancer initiation. Chin J Cancer (2013) 0.77
Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6. BMC Dev Biol (2014) 0.77
Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3. Epigenetics Chromatin (2016) 0.77
Epithelial cell identity in hyperplastic precursors of breast cancer. Chin J Cancer (2015) 0.75
Great challenges in molecular medicine: toward personalized medicine. Front Cell Dev Biol (2013) 0.75
Chromatin proteins and RNA are associated with DNA during all phases of mitosis. Cell Discov (2016) 0.75
Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70. Epigenetics Chromatin (2017) 0.75