Lee E Limbird

Author PubWeight™ 22.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Membrane trafficking of G protein-coupled receptors. Annu Rev Pharmacol Toxicol 2004 1.94
2 Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization. Circ Res 2006 1.76
3 Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors. Science 2004 1.52
4 G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction. Cell Signal 2002 1.51
5 Centralized oversight of physician-scientist faculty development at Vanderbilt: early outcomes. Acad Med 2008 1.42
6 Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine. J Neurosci 2002 1.18
7 Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation. J Biol Chem 2008 1.06
8 Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors. J Biol Chem 2003 1.03
9 Arrestin serves as a molecular switch, linking endogenous alpha2-adrenergic receptor to SRC-dependent, but not SRC-independent, ERK activation. J Biol Chem 2006 1.01
10 Regulated interactions of the alpha 2A adrenergic receptor with spinophilin, 14-3-3zeta, and arrestin 3. J Biol Chem 2002 1.00
11 Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium. J Biol Chem 2004 1.00
12 Heterozygous alpha 2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists. Proc Natl Acad Sci U S A 2002 0.99
13 Alpha 2-adrenergic agonist enrichment of spinophilin at the cell surface involves beta gamma subunits of Gi proteins and is preferentially induced by the alpha 2A-subtype. Mol Pharmacol 2005 0.98
14 Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30. Am J Physiol Cell Physiol 2009 0.96
15 Appropriate polarization following pharmacological rescue of V2 vasopressin receptors encoded by X-linked nephrogenic diabetes insipidus alleles involves a conformation of the receptor that also attains mature glycosylation. J Biol Chem 2003 0.96
16 Regulation of alpha2AR trafficking and signaling by interacting proteins. Biochem Pharmacol 2006 0.91
17 Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization. J Biol Chem 2009 0.88
18 Morphological and biochemical strategies for monitoring trafficking of epitope-tagged G protein-coupled receptors in agonist-naive and agonist-occupied states. Methods Enzymol 2002 0.82
19 Proteomic exploration of pancreatic islets in mice null for the alpha2A adrenergic receptor. J Mol Endocrinol 2005 0.80
20 Knockout of spinophilin, an endogenous antagonist of arrestin-dependent alpha2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences. Behav Brain Res 2008 0.78
21 Study of G-protein-coupled receptor-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs. Methods Mol Biol 2004 0.75
22 Study of GPCR-protein interactions using gel overlay assays and glutathione-S-transferase-fusion protein pull-downs. Methods Mol Biol 2011 0.75