PubRank

Lodewyk F A Wessels

Author PubWeight™ 96.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 2012 8.31
2 Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 2013 8.24
3 Converting a breast cancer microarray signature into a high-throughput diagnostic test. BMC Genomics 2006 4.57
4 Gene expression profiles of primary breast tumors maintained in distant metastases. Proc Natl Acad Sci U S A 2003 4.47
5 MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling. Cell 2012 4.01
6 Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer. Proc Natl Acad Sci U S A 2007 3.58
7 The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature 2012 3.23
8 An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas. Nat Genet 2005 3.04
9 MicroRNA sequence and expression analysis in breast tumors by deep sequencing. Cancer Res 2011 3.02
10 Chromatin position effects assayed by thousands of reporters integrated in parallel. Cell 2013 2.16
11 Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis. Proc Natl Acad Sci U S A 2013 2.12
12 A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer. Breast Cancer Res 2008 2.09
13 Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis. Nat Genet 2011 2.02
14 Fewer permutations, more accurate P-values. Bioinformatics 2009 1.91
15 Cross-validated Cox regression on microarray gene expression data. Stat Med 2006 1.90
16 Changes in gene expression associated with response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol 2005 1.73
17 Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells. PLoS One 2008 1.72
18 Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations. Cancer Res 2005 1.70
19 Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast Cancer Res 2006 1.69
20 Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition. Int J Cancer 2013 1.60
21 A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets. BMC Bioinformatics 2006 1.57
22 Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment. Blood 2004 1.56
23 Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue. PLoS One 2011 1.56
24 Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability. BMC Genomics 2008 1.45
25 Timely deposition of macromolecular structures is necessary for peer review. Acta Crystallogr D Biol Crystallogr 2013 1.40
26 Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines. BMC Med Genomics 2012 1.39
27 Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response. Breast Cancer Res Treat 2009 1.37
28 Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH. Breast Cancer Res Treat 2008 1.36
29 Comparison of gene expression profiles predicting progression in breast cancer patients treated with tamoxifen. Breast Cancer Res Treat 2008 1.12
30 Combinatorial effects of environmental parameters on transcriptional regulation in Saccharomyces cerevisiae: a quantitative analysis of a compendium of chemostat-based transcriptome data. BMC Genomics 2009 1.07
31 A critical evaluation of network and pathway-based classifiers for outcome prediction in breast cancer. PLoS One 2012 1.06
32 Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients. Clin Cancer Res 2010 1.05
33 Bioinformatic analysis of barcoded cDNA libraries for small RNA profiling by next-generation sequencing. Methods 2012 1.04
34 Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness. Breast Cancer Res 2011 1.03
35 Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy. Breast Cancer Res 2014 1.03
36 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. Genome Biol 2014 1.02
37 Radiation-associated breast tumors display a distinct gene expression profile. Int J Radiat Oncol Biol Phys 2010 1.01
38 Exploiting combinatorial cultivation conditions to infer transcriptional regulation. BMC Genomics 2007 1.00
39 PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer. Breast Cancer Res Treat 2010 0.99
40 Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers. BMC Cancer 2010 0.97
41 Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome. PLoS One 2012 0.93
42 Module-based outcome prediction using breast cancer compendia. PLoS One 2007 0.92
43 Computational identification of insertional mutagenesis targets for cancer gene discovery. Nucleic Acids Res 2011 0.92
44 A scale-space method for detecting recurrent DNA copy number changes with analytical false discovery rate control. Nucleic Acids Res 2013 0.89
45 Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors. PLoS One 2013 0.88
46 SERPINA6, BEX1, AGTR1, SLC26A3, and LAPTM4B are markers of resistance to neoadjuvant chemotherapy in HER2-negative breast cancer. Breast Cancer Res Treat 2012 0.87
47 A regression model for estimating DNA copy number applied to capture sequencing data. Bioinformatics 2012 0.83
48 Identifying subgroup markers in heterogeneous populations. Nucleic Acids Res 2013 0.83
49 Platform comparisons for identification of breast cancers with a BRCA-like copy number profile. Breast Cancer Res Treat 2013 0.81
50 SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets. BMC Bioinformatics 2007 0.80
51 Analysis of mass spectrometry data using sub-spectra. BMC Bioinformatics 2009 0.80
52 Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis. Proc Natl Acad Sci U S A 2014 0.79
53 Knowledge driven decomposition of tumor expression profiles. BMC Bioinformatics 2009 0.77
54 Selection of patients for hepatic surgery of colorectal cancer liver metastasis based on genomic aberrations. Ann Surg Oncol 2013 0.76
55 Protein complex prediction using an integrative bioinformatics approach. J Bioinform Comput Biol 2007 0.75
56 Corrigendum: using TRIP for genome-wide position effect analysis in cultured cells. Nat Protoc 2015 0.75