PubRank

Hai Yan

Author PubWeight™ 204.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An integrated genomic analysis of human glioblastoma multiforme. Science 2008 51.36
2 High frequency of mutations of the PIK3CA gene in human cancers. Science 2004 27.94
3 Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations. Proc Natl Acad Sci U S A 2003 12.91
4 The genetic landscape of the childhood cancer medulloblastoma. Science 2010 8.34
5 TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci U S A 2013 6.88
6 Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 2004 4.67
7 Altered telomeres in tumors with ATRX and DAXX mutations. Science 2011 4.60
8 Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature 2012 4.37
9 Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. Cancer Res 2004 4.26
10 Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget 2012 3.88
11 Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc Natl Acad Sci U S A 2011 3.66
12 Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum Mutat 2011 3.63
13 Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 2011 3.49
14 Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst 2010 3.00
15 The integrated landscape of driver genomic alterations in glioblastoma. Nat Genet 2013 2.89
16 Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma. Cancer Res 2008 2.55
17 Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid. Cancer Res 2005 2.35
18 2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations. PLoS One 2011 2.00
19 Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes. Oncotarget 2010 1.88
20 OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas. Cancer Res 2009 1.77
21 Identification of p18 INK4c as a tumor suppressor gene in glioblastoma multiforme. Cancer Res 2008 1.65
22 A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. Genome Res 2012 1.63
23 Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas. Cancer Res 2012 1.46
24 Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas. Oncotarget 2014 1.40
25 Glioblastoma multiforme: a review of therapeutic targets. Expert Opin Ther Targets 2009 1.38
26 Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements. Cancer Res 2002 1.26
27 Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia. J Pharmacol Exp Ther 2009 1.22
28 A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation. Biochem Biophys Res Commun 2009 1.22
29 Sample type bias in the analysis of cancer genomes. Cancer Res 2009 1.22
30 VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting. J Neurosci 2002 1.22
31 Glioblastoma Multiforme Oncogenomics and Signaling Pathways. Clin Med Oncol 2009 1.21
32 Exomic sequencing of four rare central nervous system tumor types. Oncotarget 2013 1.17
33 Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways. Proc Natl Acad Sci U S A 2012 1.14
34 Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target. Curr Opin Neurol 2011 1.12
35 Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers. Hum Mutat 2006 1.12
36 The genetic landscape of anaplastic astrocytoma. Oncotarget 2014 1.09
37 IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain. Biochem Biophys Res Commun 2010 1.08
38 Releasing the block: setting differentiation free with mutant IDH inhibitors. Cancer Cell 2013 1.07
39 KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation. Oncotarget 2013 1.06
40 EGFR mutations and sensitivity to gefitinib. N Engl J Med 2004 1.05
41 Mutant IDH1 is required for IDH1 mutated tumor cell growth. Oncotarget 2012 1.03
42 Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. Neoplasia 2010 1.03
43 Reversing the Warburg effect as a treatment for glioblastoma. J Biol Chem 2013 1.02
44 IDH1 and IDH2: not your typical oncogenes. Cancer Cell 2010 1.00
45 EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. J Clin Invest 2014 0.97
46 Identification of microbial DNA in human cancer. BMC Med Genomics 2009 0.95
47 Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor. Am J Physiol Endocrinol Metab 2010 0.93
48 Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling. J Biol Chem 2002 0.92
49 Pharmacological targeting of glucagon and glucagon-like peptide 1 receptors has different effects on energy state and glucose homeostasis in diet-induced obese mice. J Pharmacol Exp Ther 2011 0.90
50 HDMX regulates p53 activity and confers chemoresistance to 3-bis(2-chloroethyl)-1-nitrosourea. Neuro Oncol 2010 0.89
51 Enzyme redesign guided by cancer-derived IDH1 mutations. Nat Chem Biol 2012 0.88
52 Detection of allelic variations of human gene expression by polymerase colonies. BMC Genet 2004 0.88
53 Removal of cyanobacterial blooms in Taihu Lake using local soils. I. Equilibrium and kinetic screening on the flocculation of Microcystis aeruginosa using commercially available clays and minerals. Environ Pollut 2005 0.88
54 Glioblastoma proto-oncogene SEC61gamma is required for tumor cell survival and response to endoplasmic reticulum stress. Cancer Res 2009 0.87
55 Naringin inhibits ROS-activated MAPK pathway in high glucose-induced injuries in H9c2 cardiac cells. Basic Clin Pharmacol Toxicol 2013 0.86
56 Folic acid acts through DNA methyltransferases to induce the differentiation of neural stem cells into neurons. Cell Biochem Biophys 2013 0.86
57 Growth Performance and Meat Quality of Broiler Chickens Supplemented with Bacillus licheniformis in Drinking Water. Asian-Australas J Anim Sci 2012 0.85
58 Biodegradation of methyl parathion by Acinetobacter radioresistens USTB-04. J Environ Sci (China) 2007 0.84
59 Outbreak of neonatal gastroenteritis associated with astrovirus serotype 1 at a hospital in Inner Mongolia, China. J Clin Microbiol 2010 0.83
60 IDH1 and IDH2 hotspot mutations are not found in canine glioma. Int J Cancer 2010 0.83
61 Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. PLoS One 2012 0.83
62 Digital karyotyping technology: exploring the cancer genome. Expert Rev Mol Diagn 2005 0.81
63 [Toxic effects of hexavalent chromium on the growth of blue-green microalgae]. Huan Jing Ke Xue 2003 0.81
64 Pharmacokinetic and pharmacodynamic modeling of a monoclonal antibody antagonist of glucagon receptor in male ob/ob mice. AAPS J 2009 0.80
65 Influence of cell properties on rheological characterization of microalgae suspensions. Bioresour Technol 2013 0.80
66 Multiple CDK/CYCLIND genes are amplified in medulloblastoma and supratentorial primitive neuroectodermal brain tumor. Cancer Genet 2012 0.80
67 Genomic alterations and the pathogenesis of glioblastoma. Cell Cycle 2011 0.80
68 Microfluidic channels with ultralow-loss waveguide crossings for various chip-integrated photonic sensors. Opt Lett 2015 0.79
69 Isocitrate dehydrogenase 1: what it means to the neurosurgeon: a review. J Neurosurg 2013 0.79
70 Rapid spectrophotometric method for determining surface free energy of microalgal cells. Anal Chem 2014 0.79
71 Matrilysin-2 expression in colorectal cancer is associated with overall survival of patients. Tumour Biol 2013 0.77
72 Oral exposure to the herbicide simazine induces mouse spleen immunotoxicity and immune cell apoptosis. Toxicol Pathol 2012 0.77
73 Apples to origins: identifying brain tumor stem cell genes by comparing transcriptomes of normal and cancer stem cells. Cancer Discov 2012 0.77
74 Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors. Acta Neuropathol 2013 0.77
75 Microbial biodegradation of microcystin-RR by bacterium Sphingopyxis sp. USTB-05. J Environ Sci (China) 2010 0.76
76 An adenosine kinase in apoplastic location is involved in Magnaporthe oryzae cold acclimation. J Basic Microbiol 2013 0.76
77 Unique surface sensing property and enhanced sensitivity in microring resonator biosensors based on subwavelength grating waveguides. Opt Express 2016 0.75
78 Growth Control of Cyanobacteria by Three Submerged Macrophytes. Environ Eng Sci 2012 0.75
79 Determination of flumorph residues in vegetables, soil, and natural water by solid-phase extraction cleanup and high-performance liquid chromatography with UV detection. J AOAC Int 2009 0.75
80 A dynamic model describing heterotrophic culture of Chlorella and its stability analysis. Math Biosci Eng 2011 0.75
81 One-dimensional photonic crystal slot waveguide for silicon-organic hybrid electro-optic modulators. Opt Lett 2016 0.75
82 Policy and Practice Model of Public-Private Partnership in Public Hospitals during the New Medical Reform Period. J BUON 2016 0.75
83 Free Energy Calculations of Ionic Hydration Consistent with the Experimental Hydration Free Energy of the Proton. J Phys Chem Lett 2017 0.75
84 Improving the detection limit for on-chip photonic sensors based on subwavelength grating racetrack resonators. Opt Express 2017 0.75
85 [Studies on the extraction of ingredients from Chinese traditional medicine with CO2 supercritical fluid]. Zhongguo Zhong Yao Za Zhi 2003 0.75
86 [Advances in the pathway and molecular mechanism for the biodegradation of microcystins]. Huan Jing Ke Xue 2014 0.75
87 Degradation of flumorph in soils, aqueous buffer solutions, and natural waters. J Agric Food Chem 2008 0.75
88 [Characterization of enzymatic degradation of microcystins by a new isolated bacterium]. Huan Jing Ke Xue 2006 0.75
89 A method to extract algae toxin of microcystin-LR. J Environ Sci (China) 2004 0.75
90 [Kinetics and mechanism of removing Microcystis aeruginosa using clay flocculation]. Huan Jing Ke Xue 2003 0.75
91 Comparative Assessment of Computational Methods for Free Energy Calculations of Ionic Hydration. J Chem Inf Model 2017 0.75