| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a Caucasian population.
|
Clin Chem
|
2005
|
1.96
|
|
2
|
Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference.
|
Ther Drug Monit
|
2009
|
1.68
|
|
3
|
The intronic prothrombin 19911A>G polymorphism influences splicing efficiency and modulates effects of the 20210G>A polymorphism on mRNA amount and expression in a stable reporter gene assay system.
|
Blood
|
2003
|
1.65
|
|
4
|
6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial.
|
Clin Chem
|
2007
|
1.65
|
|
5
|
cDNA microarray analysis reveals new candidate genes possibly linked to side effects under mycophenolate mofetil therapy.
|
Transplantation
|
2004
|
1.48
|
|
6
|
Digital droplet PCR for rapid quantification of donor DNA in the circulation of transplant recipients as a potential universal biomarker of graft injury.
|
Clin Chem
|
2013
|
1.48
|
|
7
|
Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods.
|
Clin Chem
|
2003
|
1.45
|
|
8
|
The pharmacokinetic-pharmacodynamic relationship for total and free mycophenolic Acid in pediatric renal transplant recipients: a report of the german study group on mycophenolate mofetil therapy.
|
J Am Soc Nephrol
|
2002
|
1.38
|
|
9
|
Comparing mycophenolate mofetil regimens for de novo renal transplant recipients: the fixed-dose concentration-controlled trial.
|
Transplantation
|
2008
|
1.34
|
|
10
|
Gastrointestinal side effects of mycophenolic acid in renal transplant patients: a reappraisal.
|
Nephrol Dial Transplant
|
2007
|
1.30
|
|
11
|
Therapeutic drug monitoring of mycophenolate mofetil in transplantation.
|
Ther Drug Monit
|
2006
|
1.30
|
|
12
|
Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood.
|
Clin Chem
|
2002
|
1.23
|
|
13
|
Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in exon 6.
|
Ther Drug Monit
|
2007
|
1.17
|
|
14
|
Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus.
|
Clin Chem
|
2005
|
1.14
|
|
15
|
Acyl glucuronide drug metabolites: toxicological and analytical implications.
|
Ther Drug Monit
|
2003
|
1.08
|
|
16
|
Erosive enterocolitis in mycophenolate mofetil-treated renal-transplant recipients with persistent afebrile diarrhea.
|
Transplantation
|
2003
|
1.06
|
|
17
|
Proteome of conidial surface associated proteins of Aspergillus fumigatus reflecting potential vaccine candidates and allergens.
|
J Proteome Res
|
2006
|
1.04
|
|
18
|
AmpliChip CYP450 GeneChip: a new gene chip that allows rapid and accurate CYP2D6 genotyping.
|
Ther Drug Monit
|
2006
|
1.04
|
|
19
|
MODULAR ANALYTICS: A New Approach to Automation in the Clinical Laboratory.
|
J Autom Methods Manag Chem
|
2005
|
1.00
|
|
20
|
Characterization of diabetic nephropathy by urinary proteomic analysis: identification of a processed ubiquitin form as a differentially excreted protein in diabetic nephropathy patients.
|
Clin Chem
|
2007
|
0.99
|
|
21
|
N-acetylcysteine decreases lactate signal intensities in liver tissue and improves liver function in septic shock patients, as shown by magnetic resonance spectroscopy: extended case report.
|
Crit Care
|
2004
|
0.98
|
|
22
|
Proteins identified as targets of the acyl glucuronide metabolite of mycophenolic acid in kidney tissue from mycophenolate mofetil treated rats.
|
Biochimie
|
2006
|
0.97
|
|
23
|
Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.
|
Clin Chem
|
2005
|
0.97
|
|
24
|
Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer.
|
Clin Biochem
|
2008
|
0.97
|
|
25
|
Circulating regulatory T cells are reduced in obesity and may identify subjects at increased metabolic and cardiovascular risk.
|
Obesity (Silver Spring)
|
2013
|
0.96
|
|
26
|
Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients.
|
Ther Drug Monit
|
2002
|
0.95
|
|
27
|
Pharmacokinetics of mycophenolate mofetil in hematopoietic stem cell transplant recipients.
|
Ther Drug Monit
|
2007
|
0.94
|
|
28
|
Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability.
|
Expert Opin Drug Metab Toxicol
|
2005
|
0.94
|
|
29
|
Analytic aspects of monitoring therapy with thiopurine medications.
|
Ther Drug Monit
|
2004
|
0.93
|
|
30
|
Identification of NQO1 and GSTs genotype frequencies in Bulgarian patients with Balkan endemic nephropathy.
|
J Nephrol
|
2004
|
0.93
|
|
31
|
Identification of protein targets for mycophenolic acid acyl glucuronide in rat liver and colon tissue.
|
Proteomics
|
2004
|
0.93
|
|
32
|
Identification of novel autoantigen in the synovial fluid of rheumatoid arthritis patients using an immunoproteomics approach.
|
PLoS One
|
2013
|
0.92
|
|
33
|
Rifampin induces alterations in mycophenolic acid glucuronidation and elimination: implications for drug exposure in renal allograft recipients.
|
Clin Pharmacol Ther
|
2006
|
0.91
|
|
34
|
Prenatal programming of metabolic syndrome in the common marmoset is associated with increased expression of 11beta-hydroxysteroid dehydrogenase type 1.
|
Diabetes
|
2009
|
0.90
|
|
35
|
Immuno-reactive molecules identified from the secreted proteome of Aspergillus fumigatus.
|
J Proteome Res
|
2010
|
0.90
|
|
36
|
Genetic polymorphisms of cytochrome P450 among patients with Balkan endemic nephropathy (BEN).
|
Clin Biochem
|
2005
|
0.90
|
|
37
|
Biomarkers as a tool for management of immunosuppression in transplant patients.
|
Ther Drug Monit
|
2010
|
0.90
|
|
38
|
An open prospective pilot study on the use of rapamycin after penetrating high-risk keratoplasty.
|
Transplantation
|
2006
|
0.87
|
|
39
|
Liquid chromatography-tandem mass spectrometry or automated immunoassays: what are the future trends in therapeutic drug monitoring?
|
Clin Chem
|
2012
|
0.87
|
|
40
|
Circulating cytokines as markers of systemic inflammatory response in severe community-acquired pneumonia.
|
Clin Biochem
|
2004
|
0.87
|
|
41
|
Proteomics approach to identify the interacting partners of cellular prion protein and characterization of Rab7a interaction in neuronal cells.
|
J Proteome Res
|
2011
|
0.86
|
|
42
|
Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation.
|
Ther Drug Monit
|
2016
|
0.86
|
|
43
|
Pre-analytical effects of different lithium heparin plasma separation tubes in the routine clinical chemistry laboratory.
|
Clin Chem Lab Med
|
2011
|
0.85
|
|
44
|
Pharmacokinetics of meropenem in critically ill patients with severe infections.
|
Ther Drug Monit
|
2013
|
0.85
|
|
45
|
Clinical utility of a new enzymatic assay for determination of mycophenolic acid in comparison with an optimized LC-MS/MS method.
|
Ther Drug Monit
|
2009
|
0.84
|
|
46
|
No association between MDR1 (ABCB1) 2677G>T and 3435C>T polymorphism and sporadic colorectal cancer among Bulgarian patients.
|
J Cancer Res Clin Oncol
|
2007
|
0.84
|
|
47
|
Long-term pharmacokinetics of mycophenolic acid in pediatric renal transplant recipients over 3 years posttransplant.
|
Ther Drug Monit
|
2008
|
0.84
|
|
48
|
NAT2*5/*5 genotype (341T>C) is a potential risk factor for schistosomiasis-associated bladder cancer in Egyptians.
|
Ther Drug Monit
|
2005
|
0.83
|
|
49
|
Phosphoproteome profiling of substantia nigra and cortex regions of Alzheimer's disease patients.
|
J Neurochem
|
2012
|
0.83
|
|
50
|
Pharmacokinetics and safety of lidocaine and monoethylglycinexylidide in liposuction: a microdialysis study.
|
Plast Reconstr Surg
|
2004
|
0.83
|
|
51
|
Characterization of the inosine triphosphatase (ITPA) gene: haplotype structure, haplotype-phenotype correlation and promoter function.
|
Ther Drug Monit
|
2008
|
0.82
|
|
52
|
Validation of a rapid and sensitive liquid chromatography-tandem mass spectrometry method for free and total mycophenolic acid.
|
Clin Chem
|
2003
|
0.82
|
|
53
|
CYP2D6 and CYP2C19 in Papua New Guinea: High frequency of previously uncharacterized CYP2D6 alleles and heterozygote excess.
|
Int J Mol Epidemiol Genet
|
2010
|
0.82
|
|
54
|
Comparability and imprecision of 8 frequently used commercially available immunoassays for therapeutic drug monitoring.
|
Ther Drug Monit
|
2014
|
0.82
|
|
55
|
Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment.
|
Proteome Sci
|
2011
|
0.82
|
|
56
|
Analysis of the cellular Aspergillus fumigatus proteome that reacts with sera from rabbits developing an acquired immunity after experimental aspergillosis.
|
Electrophoresis
|
2010
|
0.82
|
|
57
|
Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney.
|
Nephrol Dial Transplant
|
2007
|
0.82
|
|
58
|
How delayed graft function impacts exposure to mycophenolic acid in patients after renal transplantation.
|
Ther Drug Monit
|
2011
|
0.81
|
|
59
|
Phenotypic and genotypic analysis of thiopurine s-methyltransferase polymorphism in the bulgarian population.
|
Ther Drug Monit
|
2003
|
0.81
|
|
60
|
Fetal calf serum heat inactivation and lipopolysaccharide contamination influence the human T lymphoblast proteome and phosphoproteome.
|
Proteome Sci
|
2011
|
0.81
|
|
61
|
Pharmacokinetics of mycophenolic acid and its glucuronide metabolites in stable adult liver transplant recipients with renal dysfunction on a low-dose calcineurin inhibitor regimen and mycophenolate mofetil.
|
Ther Drug Monit
|
2009
|
0.81
|
|
62
|
Intracellular ATP production in CD4+ T cells as a predictor for infection and allograft rejection in trough-level guided pediatric liver transplant recipients under calcineurin-inhibitor therapy.
|
Ther Drug Monit
|
2012
|
0.81
|
|
63
|
Cyclosporin A absorption profiles in pediatric renal transplant recipients predict the risk of acute rejection.
|
Ther Drug Monit
|
2004
|
0.80
|
|
64
|
Quantification by liquid chromatography tandem mass spectrometry of mycophenolic acid and its phenol and acyl glucuronide metabolites.
|
Clin Chem
|
2006
|
0.80
|
|
65
|
Differential proteomic analysis of lymphocytes treated with mycophenolic acid reveals caspase 3-induced cleavage of rho GDP dissociation inhibitor 2.
|
Ther Drug Monit
|
2009
|
0.80
|
|
66
|
Mycophenolic acid displays IMPDH-dependent and IMPDH-independent effects on renal fibroblast proliferation and function.
|
Ther Drug Monit
|
2010
|
0.80
|
|
67
|
Differential kidney proteome profiling in a murine model of renal fibrosis under treatment with mycophenolate mofetil.
|
Pathobiology
|
2011
|
0.80
|
|
68
|
Multicenter evaluation of a new inosine monophosphate dehydrogenase inhibition assay for quantification of total mycophenolic acid in plasma.
|
Ther Drug Monit
|
2008
|
0.80
|
|
69
|
Rapid detection of ITPA 94C>A and IVS2 + 21A>C gene mutations by real-time fluorescence PCR and in vitro demonstration of effect of ITPA IVS2 + 21A>C polymorphism on splicing efficiency.
|
Clin Chem
|
2004
|
0.80
|
|
70
|
Novel cytosolic allergens of Aspergillus fumigatus identified from germinating conidia.
|
J Proteome Res
|
2010
|
0.80
|
|
71
|
Prenatal dexamethasone exposure does not alter blood pressure and nephron number in the young adult marmoset monkey.
|
Hypertension
|
2009
|
0.80
|
|
72
|
T-786C polymorphism of the NOS-3 gene and the endothelial cell response to fluid shear stress-a proteome analysis.
|
J Proteome Res
|
2009
|
0.79
|
|
73
|
Effect of the antioxidant idebenone on adverse events under mycophenolate mofetil therapy in a rat model.
|
Transplantation
|
2008
|
0.79
|
|
74
|
Use of total and unbound imatinib and metabolite LC-MS/MS assay to understand individual responses in CML and GIST patients.
|
Ther Drug Monit
|
2011
|
0.79
|
|
75
|
Therapeutic Drug Monitoring of Everolimus: A Consensus Report.
|
Ther Drug Monit
|
2016
|
0.79
|
|
76
|
Comparison of the Emit immunoassay with HPLC for therapeutic drug monitoring of mycophenolic acid in pediatric renal-transplant recipients on mycophenolate mofetil therapy.
|
Clin Chem
|
2002
|
0.79
|
|
77
|
AcylMPAG plasma concentrations and mycophenolic acid-related side effects in patients undergoing renal transplantation are not related to the UGT2B7-840G>A gene polymorphism.
|
Ther Drug Monit
|
2008
|
0.79
|
|
78
|
Potential clinical implications of substitution of generic cyclosporine formulations for cyclosporine microemulsion (Neoral) in transplant recipients.
|
Eur J Clin Pharmacol
|
2004
|
0.79
|
|
79
|
Can the Roche hemolysis index be used for automated determination of cell-free hemoglobin? A comparison to photometric assays.
|
Clin Biochem
|
2013
|
0.79
|
|
80
|
Synergistic effects of sirolimus with cyclosporine and tacrolimus: analysis of immunosuppression on lymphocyte proliferation and activation in rat whole blood.
|
Transplantation
|
2004
|
0.78
|
|
81
|
Confronting the challenge: individualized immune monitoring after organ transplantation using the cellular immune function assay.
|
Clin Chim Acta
|
2012
|
0.78
|
|
82
|
Differential expression of proteins in brain regions of Alzheimer's disease patients.
|
Neurochem Res
|
2013
|
0.78
|
|
83
|
Plasminogen activities and concentrations in patients with sporadic Creutzfeldt-Jakob disease.
|
Neurosci Lett
|
2004
|
0.78
|
|
84
|
Monitoring cyclosporin in blood: between-assay differences at trough and 2 hours post-dose (C2).
|
Ther Drug Monit
|
2003
|
0.78
|
|
85
|
Performance evaluation of the new ADVIA Centaur system cyclosporine assay (single-step extraction).
|
Clin Chim Acta
|
2010
|
0.78
|
|
86
|
Determination of thiopurine methyltransferase activity in isolated human erythrocytes does not reflect putative in vivo enzyme inhibition by sulfasalazine.
|
Clin Chem
|
2004
|
0.77
|
|
87
|
Potential biomarkers in the sera of breast cancer patients from bahawalpur, pakistan.
|
Biomark Cancer
|
2012
|
0.77
|
|
88
|
Genotyping of CYP3A5 polymorphisms among Bulgarian patients with sporadic colorectal cancer and controls.
|
Onkologie
|
2007
|
0.77
|
|
89
|
Validation of an abbreviated pharmacokinetic profile for the estimation of mycophenolic acid exposure in pediatric renal transplant recipients.
|
Ther Drug Monit
|
2006
|
0.77
|
|
90
|
Determination of thiopurine methyltransferase phenotype in isolated human erythrocytes using a new simple nonradioactive HPLC method.
|
Ther Drug Monit
|
2003
|
0.76
|
|
91
|
Mycophenolic acid predose concentrations and renal function in a mouse model for progressive renal fibrosis.
|
Ther Drug Monit
|
2010
|
0.76
|
|
92
|
A new acute inflammatory syndrome related to the introduction of mycophenolate mofetil in patients with Wegener's granulomatosis.
|
Nephrol Dial Transplant
|
2002
|
0.76
|
|
93
|
Real-time assessment of hepatic function is related to clinical outcome in critically ill patients after polytrauma.
|
Clin Biochem
|
2007
|
0.76
|
|
94
|
Mycophenolic acid interaction with cyclosporine and tacrolimus in vitro and in vivo: evaluation of additive effects on rat blood lymphocyte function.
|
Ther Drug Monit
|
2005
|
0.76
|
|
95
|
Establishment of thiopurine S-methyltransferase gene knockdown in jurkat T-lymphocytes: an in vitro model of TPMT polymorphism.
|
Ther Drug Monit
|
2012
|
0.76
|
|
96
|
Rapid, long-range molecular haplotyping of thiopurine S-methyltransferase (TPMT) *3A, *3B, and *3C.
|
Clin Chem
|
2004
|
0.76
|
|
97
|
Allergic aspergillosis and the antigens of Aspergillus fumigatus.
|
Curr Protein Pept Sci
|
2014
|
0.76
|
|
98
|
Pharmacokinetics and bioavailability of mycophenolic acid after intravenous administration and oral administration of mycophenolate mofetil to heart transplant recipients.
|
Ther Drug Monit
|
2005
|
0.76
|
|
99
|
Regulation of IL2 and NUCB1 in mononuclear cells treated with acyl glucuronide of mycophenolic acid reveals effects independent of inosine monophosphate dehydrogenase inhibition.
|
Ther Drug Monit
|
2009
|
0.76
|
|
100
|
Chip-based genotyping: translation of pharmacogenetic research to clinical practice.
|
Clin Chem
|
2007
|
0.75
|
|
101
|
Mycophenolate sodium does not reduce the incidence of GI adverse events compared with mycophenolate mofetil.
|
Am J Transplant
|
2005
|
0.75
|
|
102
|
Formation of monoethylglycinexylidide (MEGX) in clinically healthy dogs.
|
Can J Vet Res
|
2011
|
0.75
|
|
103
|
Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor.
|
Ther Drug Monit
|
2008
|
0.75
|
|
104
|
Offie Soldin, PhD, MBA.
|
Ther Drug Monit
|
2015
|
0.75
|
|
105
|
Individually tailored immunosuppression: is there a role for biomarkers?
|
Clin Chem
|
2011
|
0.75
|
|
106
|
Pharmacokinetic Analysis of Mycophenolate Mofetil and Enteric-Coated Mycophenolate Sodium in Calcineurin Inhibitor-Free Renal Transplant Recipients.
|
Ther Drug Monit
|
2016
|
0.75
|
|
107
|
Assuring the Proper Analytical Performance of Measurement Procedures for Immunosuppressive Drug Concentrations in Clinical Practice: Recommendations of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Immunosuppressive Drug Scientific Committee.
|
Ther Drug Monit
|
2016
|
0.75
|
|
108
|
Marmoset glutathione peroxidases: cDNA sequences, molecular evolution, and gene expression.
|
J Med Primatol
|
2006
|
0.75
|
|
109
|
Single-nucleotide polymorphism of CYP3A5 impacts the exposure to tacrolimus in pediatric renal transplant recipients: A pharmacogenetic substudy of the TWIST trial.
|
Ther Drug Monit
|
2016
|
0.75
|
|
110
|
Graft-derived cell-free DNA as an early organ integrity biomarker after transplantation of a marginal HELLP syndrome donor liver.
|
Transplantation
|
2014
|
0.75
|
|
111
|
Biomarkers in transplantation medicine: guide to the next level in immunosuppressive therapy.
|
Clin Chim Acta
|
2012
|
0.75
|
|
112
|
Atypical pharmacokinetics and metabolism of mycophenolic acid in a young kidney transplant recipient with impaired renal function.
|
Ther Drug Monit
|
2002
|
0.75
|
|
113
|
Therapeutic drug monitoring and drugs of abuse testing on the cobas 6000 analyzer series: analytical performance under routine-like conditions.
|
Clin Chem Lab Med
|
2009
|
0.75
|
|
114
|
Multicenter evaluation of a new automated electrochemiluminescence immunoassay for the quantification of testosterone compared to liquid chromatography tandem mass spectrometry.
|
Clin Biochem
|
2010
|
0.75
|