Published in J Virol on March 01, 2005
HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals. AIDS Res Hum Retroviruses (2010) 1.26
HIV-1 Nef protein is secreted into vesicles that can fuse with target cells and virions. Ethn Dis (2008) 1.22
Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity. Nature (1986) 10.62
Specific incorporation of cyclophilin A into HIV-1 virions. Nature (1994) 7.13
Functional association of cyclophilin A with HIV-1 virions. Nature (1994) 6.82
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors. Nat Med (2003) 5.97
The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J Exp Med (1994) 5.22
Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis. J Virol (1995) 4.45
Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription. J Virol (1996) 4.15
Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells. EMBO J (2001) 2.64
Association of Nef with the human immunodeficiency virus type 1 core. J Virol (1999) 2.62
The human immunodeficiency virus type 1 capsid p2 domain confers sensitivity to the cyclophilin-binding drug SDZ NIM 811. J Virol (1996) 2.43
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol Cell (1999) 2.09
Disruption of the actin cytoskeleton can complement the ability of Nef to enhance human immunodeficiency virus type 1 infectivity. J Virol (2004) 2.06
Evidence for a stable interaction of gp41 with Pr55(Gag) in immature human immunodeficiency virus type 1 particles. J Virol (2000) 2.00
An intracellular block to primate lentivirus replication. Proc Natl Acad Sci U S A (2002) 1.81
Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction. Virology (1996) 1.74
Transfer of the HIV-1 cyclophilin-binding site to simian immunodeficiency virus from Macaca mulatta can confer both cyclosporin sensitivity and cyclosporin dependence. Proc Natl Acad Sci U S A (1997) 1.68
Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization. J Virol (1996) 1.59
Disassembly of human immunodeficiency virus type 1 cores in vitro reveals association of Nef with the subviral ribonucleoprotein complex. J Virol (2003) 1.55
Induction of AIDS in rhesus monkeys by a recombinant simian immunodeficiency virus expressing nef of human immunodeficiency virus type 1. J Virol (1999) 1.47
The human immunodeficiency virus type 1 nef gene can to a large extent replace simian immunodeficiency virus nef in vivo. J Virol (1999) 1.26
Mechanistic independence of Nef and cyclophilin A enhancement of human immunodeficiency virus type 1 infectivity. Virology (1998) 1.17
Cyclophilin A incorporation is not required for human immunodeficiency virus type 1 particle maturation and does not destabilize the mature capsid. Virology (1999) 1.13
Cyclophilin a plays distinct roles in human immunodeficiency virus type 1 entry and postentry events, as revealed by spinoculation. J Virol (2002) 1.05
Restoration of wild-type infectivity to human immunodeficiency virus type 1 strains lacking nef by intravirion reverse transcription. J Virol (2001) 1.05
The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable. J Virol (1997) 1.03
SIV/HIV Nef recombinant virus (SHIVnef) produces simian AIDS in rhesus macaques. Virology (1999) 1.02
HIV-1 Nef triggers Vav-mediated signaling pathway leading to functional and morphological differentiation of dendritic cells. FASEB J (2003) 0.98
Maturation-induced conformational changes of HIV-1 capsid protein and identification of two high affinity sites for cyclophilins in the C-terminal domain. J Biol Chem (1999) 0.94
Chimeric human immunodeficiency virus type 1 (HIV-1) virions containing HIV-2 or simian immunodeficiency virus Nef are resistant to cyclosporine treatment. J Virol (2004) 0.90
Treatment of human immunodeficiency virus type 1 virions depleted of cyclophilin A by natural endogenous reverse transcription restores infectivity. J Virol (2003) 0.87
Properties of a chimeric simian-human immunodeficiency virus expressing an hybrid HIV-1 Nef/SIVmac Nef protein. Arch Virol (2002) 0.79
Growth properties of HSIVnef: HIV-1 containing the nef gene from pathogenic molecular clone SIVmac239. Virus Res (1998) 0.79
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J (2007) 1.97
Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors. J Virol (2004) 1.39
Characterization of Nef-CXCR4 interactions important for apoptosis induction. J Virol (2004) 1.24
HIV-1 Nef protein is secreted into vesicles that can fuse with target cells and virions. Ethn Dis (2008) 1.22
Genetic characterization of HIV type 1 Nef-induced vesicle secretion. AIDS Res Hum Retroviruses (2010) 1.20
The role of translational research in addressing health disparities: a conceptual framework. Ethn Dis (2008) 1.20
Effect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity. J Virol (2005) 1.01
High-resolution whole-genome haplotyping using limited seed data. Nat Methods (2013) 1.01
Secretion modification region-derived peptide disrupts HIV-1 Nef's interaction with mortalin and blocks virus and Nef exosome release. J Virol (2011) 0.97
Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Invest Ophthalmol Vis Sci (2009) 0.96
Sperm proteasomes degrade sperm receptor on the egg zona pellucida during mammalian fertilization. PLoS One (2011) 0.95
DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function. Endocrinology (2008) 0.92
Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release. J Virol (2010) 0.92
Human immunodeficiency virus type 2 reverse transcriptase activity in model systems that mimic steps in reverse transcription. J Virol (2003) 0.92
Trypanosome apoptotic factor mediates apoptosis in human brain vascular endothelial cells. Mol Biochem Parasitol (2004) 0.91
Chimeric human immunodeficiency virus type 1 (HIV-1) virions containing HIV-2 or simian immunodeficiency virus Nef are resistant to cyclosporine treatment. J Virol (2004) 0.90
Addressing health disparities through multi-institutional, multidisciplinary collaboratories. Ethn Dis (2008) 0.89
Treatment of human immunodeficiency virus type 1 virions depleted of cyclophilin A by natural endogenous reverse transcription restores infectivity. J Virol (2003) 0.87
Apoptotic peptides derived from HIV-1 Nef induce lymphocyte depletion in mice. Ethn Dis (2008) 0.86
Acute neuronal injury and blood genomic profiles in a nonhuman primate model for ischemic stroke. Comp Med (2012) 0.85
The molecular epidemiology and drug resistance determination of HIV type 1 subtype B infection in Barbados. AIDS Res Hum Retroviruses (2003) 0.83
Plasmodium berghei ANKA infection increases Foxp3, IL-10 and IL-2 in CXCL-10 deficient C57BL/6 mice. Malar J (2011) 0.83
Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer. Cancer Biol Ther (2005) 0.83
HLA-G DNA sequence variants and risk of perinatal HIV-1 transmission. AIDS Res Ther (2006) 0.82
CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth. Mol Cancer Ther (2009) 0.82
Validation of a novel secretion modification region (SMR) of HIV-1 Nef using cohort sequence analysis and molecular modeling. J Mol Model (2012) 0.81
Non-syndromic hereditary gingival fibromatosis in three Chinese families is not due to SOS1 gene mutations. Cell Biochem Biophys (2014) 0.78
Nanotubes Functionalized with BMP2 Knuckle Peptide Improve the Osseointegration of Titanium Implants in Rabbits. J Biomed Nanotechnol (2015) 0.76
Detection of CD22 Expression in Living Cancer Cells by Semiconductor Quantum Dots (Journal of Biomedical Nanotechnology, Vol. 14(8), pp. 1375-1383 (2018)). J Biomed Nanotechnol (2019) 0.75