Alessio Nencioni

Author PubWeight™ 39.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Novel 2-[(benzylamino)methyl]pyrrolidine-3,4-diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies. Bioorg Med Chem 2010 1.40
2 Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE. PLoS One 2009 1.30
3 Rnai as an experimental and therapeutic tool to study and regulate physiological and disease processes. Annu Rev Physiol 2005 1.27
4 Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition. Blood 2012 1.23
5 Retracted Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1. Immunity 2003 1.15
6 Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience. Curr Drug Targets 2013 1.12
7 The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses. J Biol Chem 2012 1.11
8 Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction. Antioxid Redox Signal 2012 1.04
9 Rejuvenating sirtuins: the rise of a new family of cancer drug targets. Curr Pharm Des 2013 1.01
10 The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts. FASEB J 2011 1.01
11 NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes. J Biol Chem 2012 0.96
12 Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells. Clin Cancer Res 2004 0.94
13 Intracellular NAD⁺ depletion enhances bortezomib-induced anti-myeloma activity. Blood 2013 0.93
14 Ras-induced resistance to lapatinib is overcome by MEK inhibition. Curr Cancer Drug Targets 2010 0.92
15 Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. PLoS One 2011 0.90
16 Immunotherapy with dendritic cells for cancer. Adv Drug Deliv Rev 2007 0.89
17 A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib. Leuk Res 2010 0.89
18 Proteasome inhibitors as immunosuppressants: biological rationale and clinical experience. Semin Hematol 2012 0.88
19 Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. Exp Hematol 2010 0.88
20 Intracellular NAD(+) depletion induces autophagic death in multiple myeloma cells. Autophagy 2013 0.87
21 Discovery of novel and selective SIRT6 inhibitors. J Med Chem 2014 0.87
22 The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer. World J Surg Oncol 2013 0.86
23 Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndrome. Mediators Inflamm 2013 0.85
24 APO866 activity in hematologic malignancies: a preclinical in vitro study. Blood 2009 0.85
25 The vulnerable coronary plaque: update on imaging technologies. Thromb Haemost 2013 0.84
26 CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. J Biol Chem 2013 0.84
27 Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques. Thromb Haemost 2014 0.84
28 Nicotinamide phosphoribosyltransferase as a target in inflammation- related disorders. Curr Top Med Chem 2013 0.82
29 Treatment with the CC chemokine-binding protein Evasin-4 improves post-infarction myocardial injury and survival in mice. Thromb Haemost 2013 0.82
30 Expression of her-2/neu on acute lymphoblastic leukemias: implications for the development of immunotherapeutic approaches. Clin Cancer Res 2003 0.82
31 Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives. Clin Dev Immunol 2011 0.81
32 TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells. Eur J Immunol 2014 0.81
33 Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status. Leuk Lymphoma 2012 0.81
34 Transfection of dendritic cells with RNA induces CD4- and CD8-mediated T cell immunity against breast carcinomas and reveals the immunodominance of presented T cell epitopes. J Immunol 2003 0.79
35 Glucagon-like peptide-1 triggers protective pathways in pancreatic beta-cells exposed to glycated serum. Mediators Inflamm 2013 0.79
36 New insights into biology of chronic myeloid leukemia: implications in therapy. Curr Cancer Drug Targets 2013 0.78
37 Evaluating treatment response of chronic myeloid leukemia: emerging science and technology. Curr Cancer Drug Targets 2013 0.78
38 Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity. Bioorg Med Chem Lett 2009 0.77
39 An emerging role of glucagon-like peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes. Mediators Inflamm 2013 0.77
40 Pegfilgrastim compared with filgrastim after autologous peripheral blood stem cell transplantation in patients with solid tumours and lymphomas. Ann Hematol 2007 0.77
41 The role of proteasome in malignant diseases. J BUON 2007 0.76
42 Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols. Bioorg Med Chem 2011 0.76
43 Selectivity hot-spots of sirtuin catalytic cores. Mol Biosyst 2015 0.75