Published in J Control Release on December 15, 2004
Breaking up the correlation between efficacy and toxicity for nonviral gene delivery. Proc Natl Acad Sci U S A (2007) 1.58
Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery. J R Soc Interface (2009) 1.22
VEGF siRNA delivery system using arginine-grafted bioreducible poly(disulfide amine). Mol Pharm (2009) 1.21
Overcoming nonviral gene delivery barriers: perspective and future. Mol Pharm (2013) 1.10
Reducible poly(amido ethylenediamine) for hypoxia-inducible VEGF delivery. J Control Release (2006) 1.06
A reducible polycationic gene vector derived from thiolated low molecular weight branched polyethyleneimine linked by 2-iminothiolane. Biomaterials (2010) 1.04
Self-assembled polyethylenimine-graft-poly(epsilon-caprolactone) micelles as potential dual carriers of genes and anticancer drugs. Biomaterials (2007) 1.00
Bioreducible hyperbranched poly(amido amine)s for gene delivery. Biomacromolecules (2009) 0.98
Novel polymer carriers and gene constructs for treatment of myocardial ischemia and infarction. J Control Release (2008) 0.96
Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis. Am J Respir Crit Care Med (2008) 0.96
Reconstitutable charged polymeric (PLGA)(2)-b-PEI micelles for gene therapeutics delivery. Biomaterials (2011) 0.95
Understanding the adsorption mechanism of chitosan onto poly(lactide-co-glycolide) particles. Eur J Pharm Biopharm (2008) 0.92
Optimizing targeted gene delivery: chemical modification of viral vectors and synthesis of artificial virus vector systems. AAPS J (2006) 0.91
PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells. Int J Nanomedicine (2012) 0.90
Bioconjugation of oligonucleotides for treating liver fibrosis. Oligonucleotides (2007) 0.88
Bioreducible polymers for therapeutic gene delivery. J Control Release (2014) 0.87
Polymeric nucleic acid carriers: current issues and novel design approaches. J Control Release (2012) 0.84
Women and heart disease--physiologic regulation of gene delivery and expression: bioreducible polymers and ischemia-inducible gene therapies for the treatment of ischemic heart disease. Adv Drug Deliv Rev (2009) 0.84
Reversibly crosslinked nanocarriers for on-demand drug delivery in cancer treatment. Ther Deliv (2012) 0.83
Cationic nano-copolymers mediated IKKbeta targeting siRNA inhibit the proliferation of human Tenon's capsule fibroblasts in vitro. Mol Vis (2008) 0.82
Degradable poly(amino ester) based on poly(ethylene glycol) dimethacrylate and polyethylenimine as a gene carrier: molecular weight of PEI affects transfection efficiency. J Mater Sci Mater Med (2009) 0.81
Pharmacokinetics, pharmacodynamics and toxicology of theranostic nanoparticles. Nanoscale (2015) 0.81
pH- and ion-sensitive polymers for drug delivery. Expert Opin Drug Deliv (2013) 0.79
The effect of environmental pH on polymeric transfection efficiency. Biomaterials (2011) 0.79
Investigation of the cytokine response to NF-κB decoy oligonucleotide coated polysaccharide based nanoparticles in rheumatoid arthritis in vitro models. Arthritis Res Ther (2015) 0.78
Amphiphilic graft copolymer based on poly(styrene-co-maleic anhydride) with low molecular weight polyethylenimine for efficient gene delivery. Int J Nanomedicine (2012) 0.78
Efficient and Non-Toxic Biological Response Carrier Delivering TNF-α shRNA for Gene Silencing in a Murine Model of Rheumatoid Arthritis. Front Immunol (2016) 0.78
Bioreducible polymers as a determining factor for polyplex decomplexation rate and transfection. Biomacromolecules (2013) 0.77
Anticancer Effect and Apoptosis Induction of Gambogic Acid in Human Leukemia Cell Line K562 In Vitro. Med Sci Monit (2015) 0.77
Reversal of multidrug resistance in MCF-7/Adr cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-β-cyclodextrin nanocarrier. Int J Nanomedicine (2015) 0.77
Barriers to inhaled gene therapy of obstructive lung diseases: A review. J Control Release (2016) 0.77
Polyion complex (PIC) particles: Preparation and biomedical applications. Eur Polym J (2016) 0.77
Polymeric Materials for Gene Delivery and DNA Vaccination. Adv Mater (2008) 0.76
Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation. J Control Release (2015) 0.76
Exploring the role of polymer structure on intracellular nucleic acid delivery via polymeric nanoparticles. J Control Release (2015) 0.75
Doxorubicin-loaded aromatic imine-contained amphiphilic branched star polymer micelles: synthesis, self-assembly, and drug delivery. Int J Nanomedicine (2015) 0.75
The effects of PVP(Fe(III)) catalyst on polymer molecular weight and gene delivery via biodegradable cross-linked polyethylenimine. Pharm Res (2011) 0.75
Biologically responsive carrier-mediated anti-angiogenesis shRNA delivery for tumor treatment. Sci Rep (2016) 0.75
Efficient Inhibition of Ovarian Cancer by Gelonin Toxin Gene Delivered by Biodegradable Cationic Heparin-polyethyleneimine Nanogels. Int J Med Sci (2015) 0.75
Alkyl cross-linked low molecular weight polypropyleneimine dendrimers as efficient gene delivery vectors. Iran J Basic Med Sci (2016) 0.75
Hydrolyzable polyureas bearing hindered urea bonds. J Am Chem Soc (2014) 0.75
T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell (2008) 4.32
Current status of polymeric gene delivery systems. Adv Drug Deliv Rev (2006) 3.04
Thermosensitive sol-gel reversible hydrogels. Adv Drug Deliv Rev (2002) 2.54
siRNA delivery systems for cancer treatment. Adv Drug Deliv Rev (2009) 2.21
Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer. J Control Release (2008) 2.15
Hepatocyte growth factor suppresses vascular endothelial growth factor-induced expression of endothelial ICAM-1 and VCAM-1 by inhibiting the nuclear factor-kappaB pathway. Circ Res (2005) 1.91
Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma. Mol Ther (2006) 1.79
Thermally triggered intracellular explosion of volume transition nanogels for necrotic cell death. J Control Release (2008) 1.77
Reducible poly(amido ethylenimine)s designed for triggered intracellular gene delivery. Bioconjug Chem (2006) 1.77
All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery. Angew Chem Int Ed Engl (2009) 1.77
Folate receptor targeted biodegradable polymeric doxorubicin micelles. J Control Release (2004) 1.71
siRNA conjugate delivery systems. Bioconjug Chem (2009) 1.69
In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery. J Control Release (2008) 1.67
Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate. J Control Release (2004) 1.59
Inhibition of neointimal hyperplasia in vascular grafts by sustained perivascular delivery of paclitaxel. Kidney Int (2004) 1.56
Arginine-grafted bioreducible poly(disulfide amine) for gene delivery systems. Biomaterials (2008) 1.55
Validation of a multi-frequency electrical impedance tomography (mfEIT) system KHU Mark1: impedance spectroscopy and time-difference imaging. Physiol Meas (2008) 1.50
Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencing. Nat Mater (2010) 1.50
Surface-functionalized electrospun nanofibers for tissue engineering and drug delivery. Adv Drug Deliv Rev (2009) 1.50
Efficient siRNA delivery with non-viral polymeric vehicles. Pharm Res (2008) 1.46
Tumor targetability and antitumor effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles. J Control Release (2008) 1.44
PEG conjugated VEGF siRNA for anti-angiogenic gene therapy. J Control Release (2006) 1.44
Multilevel surgery in patients with rapid eye movement-related obstructive sleep apnea. Otolaryngol Head Neck Surg (2009) 1.43
Novel biodegradable poly(disulfide amine)s for gene delivery with high efficiency and low cytotoxicity. Bioconjug Chem (2008) 1.43
Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10. Exp Mol Med (2009) 1.42
Functional enhancement of beta cells in transplanted pancreatic islets by secretion signal peptide-linked exendin-4 gene transduction. J Control Release (2012) 1.41
Co-delivery of siRNA and paclitaxel into cancer cells by biodegradable cationic micelles based on PDMAEMA-PCL-PDMAEMA triblock copolymers. Biomaterials (2009) 1.34
Target-specific cellular uptake of PLGA nanoparticles coated with poly(L-lysine)-poly(ethylene glycol)-folate conjugate. Langmuir (2005) 1.32
Surface engineered and drug releasing pre-fabricated scaffolds for tissue engineering. Adv Drug Deliv Rev (2007) 1.28
Diabetes epidemics in Korea: reappraise nationwide survey of diabetes "diabetes in Korea 2007". Diabetes Metab J (2013) 1.22
Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle. Biomaterials (2011) 1.22
Biomimicking extracellular matrix: cell adhesive RGD peptide modified electrospun poly(D,L-lactic-co-glycolic acid) nanofiber mesh. Tissue Eng (2006) 1.22
VEGF siRNA delivery system using arginine-grafted bioreducible poly(disulfide amine). Mol Pharm (2009) 1.21
Polyethylene glycol-conjugated copolymers for plasmid DNA delivery. Pharm Res (2005) 1.20
Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels. J Control Release (2007) 1.20
Biodegradable poly(ethylenimine) for plasmid DNA delivery. J Control Release (2002) 1.19
Effects of PEG conjugation on insulin properties. Adv Drug Deliv Rev (2002) 1.18
Surface functionalized hollow manganese oxide nanoparticles for cancer targeted siRNA delivery and magnetic resonance imaging. Biomaterials (2011) 1.18
Heparin-coated gold nanoparticles for liver-specific CT imaging. Chemistry (2009) 1.17
Bioinspired synthesis and characterization of gadolinium-labeled magnetite nanoparticles for dual contrast t1- and t2-weighted magnetic resonance imaging. Bioconjug Chem (2010) 1.14
Gas foamed open porous biodegradable polymeric microspheres. Biomaterials (2006) 1.14
Amine-functionalized gold nanoparticles as non-cytotoxic and efficient intracellular siRNA delivery carriers. Int J Pharm (2008) 1.13
Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery. Biomacromolecules (2002) 1.12
A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development. Proc Natl Acad Sci U S A (2007) 1.11
Reducible poly(oligo-D-arginine) for enhanced gene expression in mouse lung by intratracheal injection. Mol Ther (2009) 1.11
An angiogenic, endothelial-cell-targeted polymeric gene carrier. Mol Ther (2002) 1.11
Hyaluronic acid modified biodegradable scaffolds for cartilage tissue engineering. Biomaterials (2005) 1.11
Hyaluronic acid-paclitaxel conjugate micelles: synthesis, characterization, and antitumor activity. Bioconjug Chem (2008) 1.11
A family of bioreducible poly(disulfide amine)s for gene delivery. Biomaterials (2009) 1.10
Extracellular HMGB1 released by NMDA treatment confers neuronal apoptosis via RAGE-p38 MAPK/ERK signaling pathway. Neurotox Res (2010) 1.10
Bioinspired Surface Immobilization of Hyaluronic Acid on Monodisperse Magnetite Nanocrystals for Targeted Cancer Imaging. Adv Mater (2008) 1.09
Novel pH sensitive block copolymer micelles for solvent free drug loading. Macromol Biosci (2006) 1.08
Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. J Control Release (2002) 1.07
Effects of background fluid on the efficiency of inactivating yeast with non-thermal atmospheric pressure plasma. PLoS One (2013) 1.07
Intracellular trafficking and unpacking of siRNA/quantum dot-PEI complexes modified with and without cell penetrating peptide: confocal and flow cytometric FRET analysis. Bioconjug Chem (2010) 1.07
Reducible poly(amido ethylenediamine) for hypoxia-inducible VEGF delivery. J Control Release (2006) 1.06
Hypoxia-inducible vascular endothelial growth factor-engineered mesenchymal stem cells prevent myocardial ischemic injury. Mol Ther (2011) 1.05
Nanomaterials for cancer therapy and imaging. Mol Cells (2011) 1.05
Catechol-functionalized chitosan/pluronic hydrogels for tissue adhesives and hemostatic materials. Biomacromolecules (2011) 1.04
Evolution of oncolytic adenovirus for cancer treatment. Adv Drug Deliv Rev (2011) 1.04
The effect of surface modification of adenovirus with an arginine-grafted bioreducible polymer on transduction efficiency and immunogenicity in cancer gene therapy. Biomaterials (2009) 1.04
PEGylated and MMP-2 specifically dePEGylated quantum dots: comparative evaluation of cellular uptake. Langmuir (2009) 1.03
ROS1 receptor tyrosine kinase, a druggable target, is frequently overexpressed in non-small cell lung carcinomas via genetic and epigenetic mechanisms. Ann Surg Oncol (2012) 1.03
Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy. J Control Release (2007) 1.02
Combined angiopoietin-1 and vascular endothelial growth factor gene transfer restores cavernous angiogenesis and erectile function in a rat model of hypercholesterolemia. Mol Ther (2005) 1.02
Self-crosslinked and reducible fusogenic peptides for intracellular delivery of siRNA. Biopolymers (2008) 1.02
Thermally sensitive cationic polymer nanocapsules for specific cytosolic delivery and efficient gene silencing of siRNA: swelling induced physical disruption of endosome by cold shock. J Control Release (2007) 1.02
Substrate-Independent Layer-by-Layer Assembly by Using Mussel-Adhesive-Inspired Polymers. Adv Mater (2008) 1.02
Heparin immobilized porous PLGA microspheres for angiogenic growth factor delivery. Pharm Res (2006) 1.01
Sp1-dependent regulation of the RTP801 promoter and its application to hypoxia-inducible VEGF plasmid for ischemic disease. Pharm Res (2004) 1.01
Poly(oligo-D-arginine) with internal disulfide linkages as a cytoplasm-sensitive carrier for siRNA delivery. Mol Ther (2010) 1.01
Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesis. J Control Release (2005) 1.01
In situ induction of dendritic cell-based T cell tolerance in humanized mice and nonhuman primates. J Exp Med (2011) 1.01
Controlled release of plasmid DNA from photo-cross-linked pluronic hydrogels. Biomaterials (2005) 1.01
Biodegradable PLGA microcarriers for injectable delivery of chondrocytes: effect of surface modification on cell attachment and function. Biotechnol Prog (2004) 1.00
A guanidinylated bioreducible polymer with high nuclear localization ability for gene delivery systems. Biomaterials (2009) 1.00
Folate immobilized and PEGylated adenovirus for retargeting to tumor cells. Bioconjug Chem (2006) 1.00
Construction of the bifunctional enzyme cellulase-beta-glucosidase from the hyperthermophilic bacterium Thermotoga maritima. Biotechnol Lett (2007) 0.99
Cationic solid lipid nanoparticles reconstituted from low density lipoprotein components for delivery of siRNA. Mol Pharm (2008) 0.99
Glucagon-like peptide-1 plasmid construction and delivery for the treatment of type 2 diabetes. Mol Ther (2005) 0.99
Progression of prostate cancer despite an extremely low serum level of prostate-specific antigen. Korean J Urol (2010) 0.99
Intracellular organelle-targeted non-viral gene delivery systems. J Control Release (2011) 0.98
Biodegradable polymeric microspheres with "open/closed" pores for sustained release of human growth hormone. J Control Release (2006) 0.98
Hyaluronic acid-polyethyleneimine conjugate for target specific intracellular delivery of siRNA. Biopolymers (2008) 0.98
Effect of Terplex/VEGF-165 gene therapy on left ventricular function and structure following myocardial infarction. VEGF gene therapy for myocardial infarction. J Control Release (2003) 0.98
Chitosan oligosaccharide-stabilized ferrimagnetic iron oxide nanocubes for magnetically modulated cancer hyperthermia. ACS Nano (2012) 0.98
Immobilization of cell adhesive RGD peptide onto the surface of highly porous biodegradable polymer scaffolds fabricated by a gas foaming/salt leaching method. Biomaterials (2004) 0.98
Protection of insulin secreting cells from nitric oxide induced cellular damage by crosslinked hemoglobin. Biomaterials (2004) 0.97