Paul A Kelly

Author PubWeight™ 45.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. Nat Cell Biol 2005 2.80
2 Prolactin: the new biology of an old hormone. Annu Rev Physiol 2002 1.82
3 Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors. Proc Natl Acad Sci U S A 2010 1.62
4 Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance. Endocrinology 2002 1.52
5 Impact of a chronic total occlusion in a non-infarct related artery on clinical outcomes following primary percutaneous intervention in acute ST-elevation myocardial infarction. J Invasive Cardiol 2014 1.42
6 Development and potential clinical uses of human prolactin receptor antagonists. Endocr Rev 2005 1.24
7 Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice. Recent Prog Horm Res 2003 1.20
8 Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue. Biochem Biophys Res Commun 2005 1.20
9 Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms. J Clin Invest 2002 1.15
10 Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL. J Biol Chem 2007 1.13
11 Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation. Proc Natl Acad Sci U S A 2006 1.12
12 Development of pure prolactin receptor antagonists. J Biol Chem 2003 1.11
13 Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors. Proc Natl Acad Sci U S A 2008 1.10
14 Effects of deletion of the prolactin receptor on ovarian gene expression. Reprod Biol Endocrinol 2003 1.10
15 Reduced recruitment and survival of primordial and growing follicles in GH receptor-deficient mice. Reproduction 2006 1.10
16 Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2. J Biol Chem 2010 1.04
17 Growth hormone is required for ovarian follicular growth. Endocrinology 2002 1.01
18 Growth hormone can act as a cytokine controlling survival and proliferation of immune cells: new insights into signaling pathways. Mol Cell Endocrinol 2002 0.96
19 Cathepsin D processes human prolactin into multiple 16K-like N-terminal fragments: study of their antiangiogenic properties and physiological relevance. Mol Endocrinol 2004 0.95
20 Benign breast diseases. J Mammary Gland Biol Neoplasia 2005 0.95
21 Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency. Endocrinology 2004 0.94
22 Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland. Am J Physiol Endocrinol Metab 2005 0.93
23 A short form of the prolactin (PRL) receptor is able to rescue mammopoiesis in heterozygous PRL receptor mice. Mol Endocrinol 2003 0.92
24 Drug Insight: prolactin-receptor antagonists, a novel approach to treatment of unresolved systemic and local hyperprolactinemia? Nat Clin Pract Endocrinol Metab 2006 0.91
25 A new mechanism for prolactin processing into 16K PRL by secreted cathepsin D. Mol Endocrinol 2006 0.90
26 New homologous bioassays for human lactogens show that agonism or antagonism of various analogs is a function of assay sensitivity. Endocrine 2003 0.88
27 Local over-expression of prolactin in differentiating mouse mammary gland induces functional defects and benign lesions, but no carcinoma. J Endocrinol 2006 0.86
28 Rational design of competitive prolactin/growth hormone receptor antagonists. J Mammary Gland Biol Neoplasia 2008 0.85
29 Prostate development and carcinogenesis in prolactin receptor knockout mice. Endocrinology 2003 0.85
30 Prolactin independent rescue of mouse corpus luteum life span: identification of prolactin and luteinizing hormone target genes. Am J Physiol Endocrinol Metab 2009 0.84
31 Zero-length cross-linking reveals that tight interactions between the extracellular and transmembrane domains of the luteinizing hormone receptor persist during receptor activation. Mol Endocrinol 2005 0.83
32 Autocrine growth hormone production prevents apoptosis and inhibits differentiation in C2C12 myoblasts. Cell Signal 2003 0.82
33 Targeted expression of the dominant-negative prolactin receptor in the mammary gland of transgenic mice results in impaired lactation. Endocrinology 2003 0.82
34 Should primary percutaneous coronary intervention be the routine reperfusion strategy in octogenarians presenting with ST elevation myocardial infarction? J Cardiovasc Med (Hagerstown) 2014 0.81
35 The N-terminus of human prolactin modulates its biological properties. Mol Cell Endocrinol 2003 0.80
36 Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor. Endocrinology 2002 0.80
37 Medullary thyroid carcinoma arises in the absence of prolactin signaling. Cancer Res 2005 0.80
38 Decysin, a new member of the metalloproteinase family, is regulated by prolactin and steroids during mouse pregnancy. Biol Reprod 2002 0.79
39 Male reproductive function is not affected in prolactin receptor-deficient mice. Endocrinology 2003 0.78
40 Jak2 and proteasome activities control the availability of cell surface growth hormone receptors during ligand exposure. Cell Signal 2003 0.78
41 Characterization of a prolactin-regulated gene in reproductive tissues using the prolactin receptor knockout mouse model. Biol Reprod 2002 0.78
42 Growth-promoting actions of prolactin, the hormone of lactation. J Pediatr Endocrinol Metab 2002 0.77
43 Development of new prolactin analogs acting as pure prolactin receptor antagonists. Pituitary 2003 0.77
44 Autocrine prolactin as a promotor of mammary tumour growth. J Dairy Res 2005 0.76
45 Comparison of bivalirudin with heparin versus abciximab with heparin for primary percutaneous coronary intervention in "Real World" practice. Cardiovasc Revasc Med 2013 0.75
46 The advantages of a consultant led primary percutaneous coronary intervention service on patient outcome. QJM 2013 0.75
47 Comparison of clinical characteristics and outcomes in patients with left bundle branch block versus ST-elevation myocardial infarction referred for primary percutaneous coronary intervention. Coron Artery Dis 2015 0.75
48 Rescue of Preimplantatory Egg Development and Embryo Implantation in Prolactin Receptor-Deficient Mice after Progesterone Administration. Endocrinology 2000 0.75