Medical therapy of epilepsy: when to initiate treatment and when to combine?

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How long does it take for partial epilepsy to become intractable? Neurology (2003) 3.15

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The mechanisms of action of commonly used antiepileptic drugs. Pharmacol Ther (2001) 1.28

Lost years: delayed referral for surgically treatable epilepsy. Neurology (2003) 1.27

Cognitive side-effects of chronic antiepileptic drug treatment: a review of 25 years of research. Epilepsy Res (1995) 1.19

Staged approach to epilepsy management. Neurology (2002) 1.16

Response to first drug trial predicts outcome in childhood temporal lobe epilepsy. Neurology (2001) 1.16

The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction. Epilepsia (1999) 1.11

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Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed. Epilepsia (2000) 0.99

Sudden death in epilepsy: a wake-up call for management. Lancet (2002) 0.95

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Valproate-ethosuximide combination therapy for refractory absence seizures. Arch Neurol (1983) 0.90

Seizure freedom with more than one antiepileptic drug. Seizure (2002) 0.88

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The star systems: overview and use in determining antiepileptic drug choice. CNS Drugs (2001) 0.84

Current evidence indicates that antiepileptic drugs are anti-ictal, not antiepileptic. Epilepsy Res (2002) 0.83

Measuring the efficacy of antiepileptic drugs. Seizure (2003) 0.83

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Lamotrigine and topiramate may be a useful combination. Lancet (1998) 0.77

Changing view of prognosis of epilepsy. BMJ (1990) 0.75

Success or failure with antiepileptic drug therapy: Beyond empiricism? Neurology (2003) 0.75