Published in J Gerontol A Biol Sci Med Sci on January 01, 2005
Prognostic significance of potential frailty criteria. J Am Geriatr Soc (2008) 2.69
Predicting ADL disability in community-dwelling elderly people using physical frailty indicators: a systematic review. BMC Geriatr (2011) 2.21
Rapid correction of low vitamin D status in nursing home residents. Osteoporos Int (2008) 1.97
Use of the Short Physical Performance Battery Score to predict loss of ability to walk 400 meters: analysis from the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2009) 1.83
Poor sleep is associated with poorer physical performance and greater functional limitations in older women. Sleep (2007) 1.82
In vivo and in vitro evidence that intrinsic upper- and lower-limb skeletal muscle function is unaffected by ageing and disuse in oldest-old humans. Acta Physiol (Oxf) (2015) 1.52
Menopausal status and physical performance in midlife: findings from a British birth cohort study. Menopause (2008) 1.49
Lifetime occupation and physical function: a prospective cohort study on persons aged 80 years and older living in a community. Occup Environ Med (2006) 1.47
Differences in brain structure and function in older adults with self-reported disabling and nondisabling chronic low back pain. Pain Med (2010) 1.46
Association of slower walking speed with incident knee osteoarthritis-related outcomes. Arthritis Care Res (Hoboken) (2012) 1.37
Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study. BMC Geriatr (2010) 1.35
Combinations of motor measures more strongly predict adverse health outcomes in old age: the rush memory and aging project, a community-based cohort study. BMC Med (2011) 1.33
Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis. PLoS One (2011) 1.28
Screen-based sedentary behavior, physical activity, and muscle strength in the English longitudinal study of ageing. PLoS One (2013) 1.26
The 6-minute walk is associated with frailty and predicts mortality in older adults with heart failure. Congest Heart Fail (2010) 1.26
Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed. Exp Gerontol (2008) 1.25
Muscle strength and BMI as predictors of major mobility disability in the Lifestyle Interventions and Independence for Elders pilot (LIFE-P). J Gerontol A Biol Sci Med Sci (2011) 1.22
Cognitive function is associated with the development of mobility impairments in community-dwelling elders. Am J Geriatr Psychiatry (2011) 1.20
Sensor systems for monitoring functional status in assisted living facility residents. Res Gerontol Nurs (2008) 1.16
Effects of a DVD-delivered exercise intervention on physical function in older adults. J Gerontol A Biol Sci Med Sci (2013) 1.14
Drosophila as a model for age-related impairment in locomotor and other behaviors. Exp Gerontol (2010) 1.13
Epidemiology of aging. Radiol Clin North Am (2008) 1.06
Exercise for falls prevention in Parkinson disease: a randomized controlled trial. Neurology (2014) 1.03
Evolution of an Early Illness Warning System to Monitor Frail Elders in Independent Living. J Healthc Eng (2011) 1.02
A systematic review of dynamometry and its role in hand trauma assessment. Open Orthop J (2012) 1.01
Exploring the hierarchy of mobility performance in high-functioning older women. J Gerontol A Biol Sci Med Sci (2007) 1.01
Respiratory impairment in older persons: when less means more. Am J Med (2012) 1.00
Magnesium and muscle performance in older persons: the InCHIANTI study. Am J Clin Nutr (2006) 1.00
Physical activity and functional limitations in older adults: the influence of self-efficacy and functional performance. J Gerontol B Psychol Sci Soc Sci (2012) 0.99
Kyphosis and decline in physical function over 15 years in older community-dwelling women: the Study of Osteoporotic Fractures. J Gerontol A Biol Sci Med Sci (2013) 0.98
Management of Dementia and Depression Utilizing In- Home Passive Sensor Data. Gerontechnology (2013) 0.96
Outcome measures in cardiopulmonary physical therapy: short physical performance battery. Cardiopulm Phys Ther J (2008) 0.96
Relationship of physical function to vastus lateralis capillary density and metabolic enzyme activity in elderly men and women. Aging Clin Exp Res (2008) 0.95
Association of dynamic joint power with functional limitations in older adults with symptomatic knee osteoarthritis. Arch Phys Med Rehabil (2009) 0.94
Heterogeneity of physical function responses to exercise training in older adults. J Am Geriatr Soc (2015) 0.93
Longitudinal association between self-rated health and timed gait among older persons. J Gerontol B Psychol Sci Soc Sci (2009) 0.93
A randomized controlled trial of an activity specific exercise program for individuals with Alzheimer disease in long-term care settings. J Geriatr Phys Ther (2011) 0.92
Socio-economic disadvantage from childhood to adulthood and locomotor function in old age: a lifecourse analysis of the Boyd Orr and Caerphilly prospective studies. J Epidemiol Community Health (2010) 0.91
Loss of motor function in preclinical Alzheimer's disease. Expert Rev Neurother (2011) 0.91
Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology. J Gerontol A Biol Sci Med Sci (2015) 0.91
A forward genetic screen in Drosophila implicates insulin signaling in age-related locomotor impairment. Exp Gerontol (2009) 0.90
Performance-based assessments and demand for personal care in older Japanese people: a cross-sectional study. BMJ Open (2013) 0.86
The Prediction of ADL and IADL Disability Using Six Physical Indicators of Frailty: A Longitudinal Study in the Netherlands. Curr Gerontol Geriatr Res (2014) 0.86
Association of the veterans aging cohort study index with exercise capacity in HIV-infected adults. AIDS Res Hum Retroviruses (2013) 0.84
Minimising disability and falls in older people through a post-hospital exercise program: a protocol for a randomised controlled trial and economic evaluation. BMC Geriatr (2009) 0.84
Development of a screening program to assess motor function in the adult population: a cross-sectional observational study. J Orthop Sci (2015) 0.84
Cellular aging of skeletal muscle: telomeric and free radical evidence that physical inactivity is responsible and not age. Clin Sci (Lond) (2014) 0.83
Association between chair stand strategy and mobility limitations in older adults with symptomatic knee osteoarthritis. Arch Phys Med Rehabil (2012) 0.83
Self-reported chronic pain is associated with physical performance in older people leaving aged care rehabilitation. Clin Interv Aging (2014) 0.82
Yoga Improves Upper-Extremity Function and Scapular Posturing in Persons with Hyperkyphosis. J Yoga Phys Ther (2012) 0.81
Effect of new disability subtype on 3-year mortality in Chinese older adults. J Am Geriatr Soc (2010) 0.81
Poor lower extremity function was associated with pre-diabetes and diabetes in older chinese people. PLoS One (2014) 0.80
Harvest for health gardening intervention feasibility study in cancer survivors. Acta Oncol (2013) 0.80
Associations of insulin and insulin-like growth factors with physical performance in old age in the Boyd Orr and Caerphilly studies. PLoS One (2012) 0.80
The influence of ACE ID and ACTN3 R577X polymorphisms on lower-extremity function in older women in response to high-speed power training. BMC Geriatr (2013) 0.79
Progressive and accelerated disability onset by race/ethnicity and education among late midlife and older adults. J Aging Health (2012) 0.79
A New Paradigm of Technology-Enabled ‘Vital Signs’ for Early Detection of Health Change for Older Adults. Gerontology (2015) 0.79
A new classification of function and disability in China: subtypes based on performance-based and self-reported measures. J Aging Health (2012) 0.78
The resveratrol-enriched rice DJ526 boosts motor coordination and physical strength. Sci Rep (2016) 0.78
Changes in physical performance in older women according to presence and treatment of diabetes mellitus. J Am Geriatr Soc (2013) 0.78
Long-term exercise in older adults: 4-year outcomes of music-based multitask training. Calcif Tissue Int (2014) 0.77
Assessing the agreement between 3-meter and 6-meter walk tests in 136 community-dwelling older adults. J Aging Health (2014) 0.77
Validity and applicability of a video-based animated tool to assess mobility in elderly Latin American populations. Geriatr Gerontol Int (2013) 0.77
Predictors of the antibody response to influenza vaccination in older adults with type 2 diabetes. BMJ Open Diabetes Res Care (2015) 0.76
Assessing physical functioning in otolaryngology: feasibility of the Short Physical Performance Battery. Am J Otolaryngol (2014) 0.76
Psychosocial Variables Related to Why Women are Less Active than Men and Related Health Implications. Clin Med Insights Womens Health (2016) 0.75
Prediction of Mobility Limitations after Hospitalization in Older Medical Patients by Simple Measures of Physical Performance Obtained at Admission to the Emergency Department. PLoS One (2016) 0.75
Atrial Fibrillation and Declining Physical Performance in Older Adults: The Health, Aging, and Body Composition Study. Circ Arrhythm Electrophysiol (2016) 0.75
The recursive effects of quality of life and functional limitation among older adult cancer patients: evidence from the Survey of Health, Ageing and Retirement in Europe. Eur J Cancer Care (Engl) (2015) 0.75
The Efficacy of Interdisciplinary Rehabilitation for Improving Function in People with Chronic Pain. Pain Res Treat (2016) 0.75
Association Between Hospital Readmission and Acute and Sustained Delays in Functional Recovery During 18 Months After Elective Surgery: The Successful Aging after Elective Surgery Study. J Am Geriatr Soc (2016) 0.75
Measures of fine motor skills in people with tremor disorders: appraisal and interpretation. Front Neurol (2013) 0.75
Age-related changes in bilateral upper extremity coordination. Curr Geriatr Rep (2016) 0.75
Development and application of a multi-axis dynamometer for measuring grip force. Ergonomics (2013) 0.75
Disability Rises Gradually for a Cohort of Older Americans. J Gerontol B Psychol Sci Soc Sci (2016) 0.75
The Association between Frailty and Cognition in Elderly Women. Korean J Fam Med (2016) 0.75
Age-related changes in hand dominance and functional asymmetry in older adults. PLoS One (2017) 0.75
Thoracic Kyphosis and Physical Function: The Framingham Study. J Am Geriatr Soc (2017) 0.75
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA (2005) 20.53
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature (2009) 19.56
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Gait speed and survival in older adults. JAMA (2011) 15.01
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci (2004) 12.46
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet (2010) 8.74
Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry (2010) 8.02
Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci (2006) 8.00
Patterns of functional decline at the end of life. JAMA (2003) 7.79
Physical performance measures in the clinical setting. J Am Geriatr Soc (2003) 7.67
Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis. JAMA (2003) 7.42
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation (2005) 6.89
Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc (2006) 6.81
Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci (2006) 6.61
Frailty consensus: a call to action. J Am Med Dir Assoc (2013) 6.54
Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2005) 6.54
Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial. Arthritis Rheum (2004) 6.46
Detection of life-threatening prostate cancer with prostate-specific antigen velocity during a window of curability. J Natl Cancer Inst (2006) 6.02
Ginkgo biloba for prevention of dementia: a randomized controlled trial. JAMA (2008) 6.00
Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood (2004) 5.86
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report. J Am Geriatr Soc (2004) 5.80
Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol (1985) (2003) 5.73
Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg (2010) 5.72
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med (2010) 5.20
Frailty: an emerging research and clinical paradigm--issues and controversies. J Gerontol A Biol Sci Med Sci (2007) 4.98
Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med (2002) 4.97
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet (2008) 4.75
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet (2008) 4.69
Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation (2003) 4.67
Hearing loss and incident dementia. Arch Neurol (2011) 4.65
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Differences in life expectancy due to race and educational differences are widening, and many may not catch up. Health Aff (Millwood) (2012) 4.36
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms. JAMA (2004) 4.27
Hearing loss and cognitive decline in older adults. JAMA Intern Med (2013) 4.25
Hearing loss prevalence in the United States. Arch Intern Med (2011) 4.22
Chronic musculoskeletal pain and the occurrence of falls in an older population. JAMA (2009) 4.18
The origins of age-related proinflammatory state. Blood (2004) 4.15
Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: a randomized controlled trial. JAMA (2011) 4.09
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci (2002) 4.00
Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 3.96
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study. Lancet (2002) 3.88
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes (2008) 3.76
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
The association between obesity and the frailty syndrome in older women: the Women's Health and Aging Studies. J Am Geriatr Soc (2005) 3.73
Red blood cell distribution width and the risk of death in middle-aged and older adults. Arch Intern Med (2009) 3.71
Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J Clin Endocrinol Metab (2005) 3.70
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Cognitive impairment and decline are associated with carotid artery disease in patients without clinically evident cerebrovascular disease. Ann Intern Med (2004) 3.66
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Arch Gen Psychiatry (2010) 3.64
Hearing loss prevalence and risk factors among older adults in the United States. J Gerontol A Biol Sci Med Sci (2011) 3.63
Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care (2008) 3.54
Agreement between self-report of disease diagnoses and medical record validation in disabled older women: factors that modify agreement. J Am Geriatr Soc (2004) 3.52
Thyroid status, cardiovascular risk, and mortality in older adults. JAMA (2006) 3.50
Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc (2004) 3.48
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40