| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial.
|
Lancet Oncol
|
2009
|
21.94
|
|
2
|
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
|
J Natl Cancer Inst
|
2005
|
13.00
|
|
3
|
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.
|
Cancer Res
|
2006
|
4.72
|
|
4
|
Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.
|
Cancer Res
|
2005
|
4.25
|
|
5
|
PIK3CA mutations and copy number gains in human lung cancers.
|
Cancer Res
|
2008
|
3.42
|
|
6
|
The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers.
|
Clin Cancer Res
|
2005
|
3.11
|
|
7
|
Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
|
Proc Natl Acad Sci U S A
|
2012
|
2.89
|
|
8
|
Genetic predictors of MEK dependence in non-small cell lung cancer.
|
Cancer Res
|
2008
|
2.71
|
|
9
|
Postoperative perforation in the bronchus intermedius membrane after a primary lung cancer resection.
|
Eur J Cardiothorac Surg
|
2007
|
2.66
|
|
10
|
Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.
|
PLoS One
|
2009
|
1.94
|
|
11
|
Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay.
|
Clin Cancer Res
|
2006
|
1.91
|
|
12
|
RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells.
|
Cancer Res
|
2004
|
1.84
|
|
13
|
Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features.
|
Clin Cancer Res
|
2002
|
1.74
|
|
14
|
Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas.
|
J Natl Cancer Inst
|
2013
|
1.65
|
|
15
|
CT fluoroscopy-guided biopsy of 1,000 pulmonary lesions performed with 20-gauge coaxial cutting needles: diagnostic yield and risk factors for diagnostic failure.
|
Chest
|
2009
|
1.60
|
|
16
|
Epigenetic regulation of a novel tumor suppressor gene (hDAB2IP) in prostate cancer cell lines.
|
J Biol Chem
|
2002
|
1.55
|
|
17
|
Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells.
|
Cancer Res
|
2013
|
1.54
|
|
18
|
Suppression of inflammatory cytokines during ex vivo lung perfusion with an adsorbent membrane.
|
Ann Thorac Surg
|
2010
|
1.49
|
|
19
|
MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors.
|
Int J Cancer
|
2009
|
1.48
|
|
20
|
Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers.
|
Int J Cancer
|
2005
|
1.45
|
|
21
|
Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines.
|
Oncogene
|
2002
|
1.43
|
|
22
|
EGFR mutation and response of lung cancer to gefitinib.
|
N Engl J Med
|
2005
|
1.42
|
|
23
|
Elevated serum level of sialylated glycoprotein KL-6 predicts a poor prognosis in patients with non-small cell lung cancer treated with gefitinib.
|
Lung Cancer
|
2007
|
1.40
|
|
24
|
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer.
|
Clin Cancer Res
|
2004
|
1.39
|
|
25
|
Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.
|
Cancer Res
|
2002
|
1.39
|
|
26
|
Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers.
|
Int J Cancer
|
2003
|
1.39
|
|
27
|
Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types.
|
Int J Cancer
|
2004
|
1.32
|
|
28
|
Promoter hypermethylation profile of ovarian epithelial neoplasms.
|
Clin Cancer Res
|
2005
|
1.31
|
|
29
|
Sequential molecular changes during multistage pathogenesis of small peripheral adenocarcinomas of the lung.
|
J Thorac Oncol
|
2008
|
1.30
|
|
30
|
Retracted
DNA methylation profiles of lymphoid and hematopoietic malignancies.
|
Clin Cancer Res
|
2004
|
1.26
|
|
31
|
Retracted
Aberrant methylation profile of human malignant mesotheliomas and its relationship to SV40 infection.
|
Oncogene
|
2005
|
1.25
|
|
32
|
Alterations in the mitochondrial displacement loop in lung cancers.
|
Clin Cancer Res
|
2003
|
1.23
|
|
33
|
The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer.
|
Oncogene
|
2005
|
1.23
|
|
34
|
Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies.
|
Int J Cancer
|
2005
|
1.21
|
|
35
|
Impact of EGFR mutation analysis in non-small cell lung cancer.
|
Lung Cancer
|
2008
|
1.20
|
|
36
|
Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy.
|
Lung Cancer
|
2012
|
1.17
|
|
37
|
Aberrant promoter methylation of insulin-like growth factor binding protein-3 gene in human cancers.
|
Int J Cancer
|
2007
|
1.16
|
|
38
|
Usefulness of EGFR mutation screening in pleural fluid to predict the clinical outcome of gefitinib treated patients with lung cancer.
|
Int J Cancer
|
2006
|
1.15
|
|
39
|
Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma.
|
Cancer Res
|
2002
|
1.13
|
|
40
|
ERCC1 protein expression predicts the response of cisplatin-based neoadjuvant chemotherapy in non-small-cell lung cancer.
|
Lung Cancer
|
2007
|
1.11
|
|
41
|
Sirolimus ameliorated post lung transplant chylothorax in lymphangioleiomyomatosis.
|
Ann Thorac Surg
|
2008
|
1.09
|
|
42
|
The impact of epidermal growth factor receptor gene status on gefitinib-treated Japanese patients with non-small-cell lung cancer.
|
Int J Cancer
|
2007
|
1.09
|
|
43
|
Risk factors for recurrence and unfavorable prognosis in patients with stage I non-small cell lung cancer and a tumor diameter of 20 mm or less.
|
J Thorac Oncol
|
2007
|
1.07
|
|
44
|
Concern
Differential inactivation of caspase-8 in lung cancers.
|
Cancer Biol Ther
|
2002
|
1.07
|
|
45
|
EGFR mutation status in pleural fluid predicts tumor responsiveness and resistance to gefitinib.
|
Lung Cancer
|
2007
|
1.05
|
|
46
|
Clinical significance of epidermal growth factor receptor gene mutations on treatment outcome after first-line cytotoxic chemotherapy in Japanese patients with non-small cell lung cancer.
|
J Thorac Oncol
|
2007
|
1.05
|
|
47
|
Double mutation and gene copy number of EGFR in gefitinib refractory non-small-cell lung cancer.
|
Lung Cancer
|
2006
|
1.04
|
|
48
|
Hereditary lung cancer syndrome targets never smokers with germline EGFR gene T790M mutations.
|
J Thorac Oncol
|
2014
|
1.04
|
|
49
|
Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma.
|
Clin Cancer Res
|
2011
|
1.03
|
|
50
|
Clinical outcomes of short hook wire and suture marking system in thoracoscopic resection for pulmonary nodules.
|
Eur J Cardiothorac Surg
|
2009
|
1.03
|
|
51
|
The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells.
|
Breast Cancer Res
|
2010
|
1.02
|
|
52
|
Detection of EGFR gene mutations using the wash fluid of CT-guided biopsy needle in NSCLC patients.
|
J Thorac Oncol
|
2008
|
1.02
|
|
53
|
Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer.
|
Lung Cancer
|
2011
|
1.01
|
|
54
|
Dose effect of smoking on aberrant methylation in non-small cell lung cancers.
|
Int J Cancer
|
2004
|
1.00
|
|
55
|
Percutaneous radiofrequency ablation of clinical stage I non-small cell lung cancer.
|
J Thorac Cardiovasc Surg
|
2011
|
0.99
|
|
56
|
Establishment and validation of real-time polymerase chain reaction method for CDH1 promoter methylation.
|
Am J Pathol
|
2002
|
0.99
|
|
57
|
Sirolimus amelioration of clinical symptoms of recurrent lymphangioleiomyomatosis after living-donor lobar lung transplantation.
|
J Heart Lung Transplant
|
2008
|
0.98
|
|
58
|
Aberrant methylation of TMS1 in small cell, non small cell lung cancer and breast cancer.
|
Int J Cancer
|
2003
|
0.97
|
|
59
|
Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation.
|
Cancer Sci
|
2007
|
0.97
|
|
60
|
Decreased expression of the SIN3A gene, a candidate tumor suppressor located at the prevalent allelic loss region 15q23 in non-small cell lung cancer.
|
Lung Cancer
|
2007
|
0.97
|
|
61
|
Feasibility of percutaneous radiofrequency ablation for intrathoracic malignancies: a large single-center experience.
|
Cancer
|
2007
|
0.96
|
|
62
|
Mutations of epidermal growth factor receptor and K-ras genes in adenosquamous carcinoma of the lung.
|
Int J Cancer
|
2006
|
0.96
|
|
63
|
The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor.
|
Lung Cancer
|
2011
|
0.96
|
|
64
|
Downregulation of microRNA-34 induces cell proliferation and invasion of human mesothelial cells.
|
Oncol Rep
|
2013
|
0.96
|
|
65
|
Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification.
|
Oncogene
|
2002
|
0.95
|
|
66
|
Presence of simian virus 40 DNA sequences in human lymphoid and hematopoietic malignancies and their relationship to aberrant promoter methylation of multiple genes.
|
Cancer Res
|
2004
|
0.95
|
|
67
|
Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer.
|
Lung Cancer
|
2011
|
0.95
|
|
68
|
Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas.
|
Oncol Rep
|
2004
|
0.95
|
|
69
|
Technique for creation of artificial pneumothorax for pain relief during radiofrequency ablation of peripheral lung tumors: report of seven cases.
|
J Vasc Interv Radiol
|
2011
|
0.95
|
|
70
|
Comprehensive analysis of EGFR signaling pathways in Japanese patients with non-small cell lung cancer.
|
Lung Cancer
|
2009
|
0.95
|
|
71
|
CT fluoroscopy-guided cutting needle biopsy of focal pure ground-glass opacity lung lesions: diagnostic yield in 83 lesions.
|
Eur J Radiol
|
2010
|
0.93
|
|
72
|
DNA methylation of multiple genes and clinicopathological relationship of non-small cell lung cancers.
|
Oncol Rep
|
2004
|
0.93
|
|
73
|
SYT-SSX fusion genes in synovial sarcoma of the thorax.
|
Lung Cancer
|
2004
|
0.92
|
|
74
|
Impact of age on epidermal growth factor receptor mutation in lung cancer.
|
Lung Cancer
|
2012
|
0.92
|
|
75
|
Promoter methylation downregulates CDX2 expression in colorectal carcinomas.
|
Oncol Rep
|
2005
|
0.90
|
|
76
|
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
|
J Cancer Res Clin Oncol
|
2009
|
0.90
|
|
77
|
DNA methylation in small lung adenocarcinoma with bronchioloalveolar carcinoma components.
|
Lung Cancer
|
2009
|
0.90
|
|
78
|
Age-related methylation in normal colon mucosa differs between the proximal and distal colon in patients who underwent colonoscopy.
|
Clin Biochem
|
2008
|
0.90
|
|
79
|
Impact of GLUT1 and Ki-67 expression on early‑stage lung adenocarcinoma diagnosed according to a new international multidisciplinary classification.
|
Oncol Rep
|
2012
|
0.90
|
|
80
|
Role of computed tomography fluoroscopy-guided cutting needle biopsy of lung lesions after transbronchial examination resulting in negative diagnosis.
|
Clin Lung Cancer
|
2011
|
0.89
|
|
81
|
Basal segmental auto-transplantation after pneumonectomy for advanced central lung cancer.
|
Eur J Cardiothorac Surg
|
2012
|
0.89
|
|
82
|
EGFR mutation testing practices within the Asia Pacific region: results of a multicenter diagnostic survey.
|
J Thorac Oncol
|
2015
|
0.88
|
|
83
|
Frequent p16 inactivation by homozygous deletion or methylation is associated with a poor prognosis in Japanese patients with pleural mesothelioma.
|
Lung Cancer
|
2008
|
0.88
|
|
84
|
Antitumor effect of gefitinib ('Iressa') on esophageal squamous cell carcinoma cell lines in vitro and in vivo.
|
Cancer Lett
|
2005
|
0.87
|
|
85
|
Aberrant promoter methylation in pleural fluid DNA for diagnosis of malignant pleural effusion.
|
Int J Cancer
|
2007
|
0.87
|
|
86
|
The relationship between NY-ESO-1 mRNA expression and clinicopathological features in non-small cell lung cancer.
|
Oncol Rep
|
2004
|
0.87
|
|
87
|
Brachial nerve injury caused by percutaneous radiofrequency ablation of apical lung cancer: a report of four cases.
|
J Vasc Interv Radiol
|
2010
|
0.86
|
|
88
|
Validity of using lobe-specific regional lymph node stations to assist navigation during lymph node dissection in early stage non-small cell lung cancer patients.
|
Surg Today
|
2013
|
0.85
|
|
89
|
Long-term improvement in pulmonary function after living donor lobar lung transplantation.
|
J Heart Lung Transplant
|
2007
|
0.84
|
|
90
|
Extracorporeal membrane oxygenation bridging to living-donor lobar lung transplantation.
|
Ann Thorac Surg
|
2009
|
0.84
|
|
91
|
Non-BAC component but not epidermal growth factor receptor gene mutation is associated with poor outcomes in small adenocarcinoma of the lung.
|
J Thorac Oncol
|
2008
|
0.83
|
|
92
|
Drug resistance to EGFR tyrosine kinase inhibitors for non-small cell lung cancer.
|
Acta Med Okayama
|
2014
|
0.83
|
|
93
|
The degree of microRNA-34b/c methylation in serum-circulating DNA is associated with malignant pleural mesothelioma.
|
Lung Cancer
|
2013
|
0.83
|
|
94
|
DNA methylation status of REIC/Dkk-3 gene in human malignancies.
|
J Cancer Res Clin Oncol
|
2012
|
0.83
|
|
95
|
Induction chemoradiotherapy followed by surgical resection for clinical T3 or T4 locally advanced non-small cell lung cancer.
|
Ann Surg Oncol
|
2012
|
0.83
|
|
96
|
Knockdown of the epidermal growth factor receptor gene to investigate its therapeutic potential for the treatment of non-small-cell lung cancers.
|
Clin Lung Cancer
|
2012
|
0.83
|
|
97
|
Primary thymic adenocarcinoma with production of carbohydrate antigen 19-9 and carcinoembryonic antigen.
|
Jpn J Thorac Cardiovasc Surg
|
2004
|
0.83
|
|
98
|
Epigenetic inactivation of laminin-5-encoding genes in lung cancers.
|
Clin Cancer Res
|
2003
|
0.83
|
|
99
|
Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung.
|
J Clin Oncol
|
2007
|
0.83
|
|
100
|
The epidermal growth factor receptor D761Y mutation and effect of tyrosine kinase inhibitor.
|
Clin Cancer Res
|
2007
|
0.83
|
|
101
|
Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer.
|
Int J Cancer
|
2004
|
0.83
|
|
102
|
The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas.
|
Oncol Rep
|
2008
|
0.83
|
|
103
|
Bronchial mucoepidermoid carcinoma with recurrent hemoptysis in a pregnant woman: report of a case.
|
Surg Today
|
2008
|
0.83
|
|
104
|
Impact of prolonged cold preservation on the graft function and gene expression levels in an experimental lung transplantation model.
|
Surg Today
|
2012
|
0.82
|
|
105
|
Spontaneous regression of primary lung cancer arising from an emphysematous bulla.
|
Ann Thorac Cardiovasc Surg
|
2011
|
0.82
|
|
106
|
Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers.
|
Oncol Rep
|
2004
|
0.82
|
|
107
|
Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer.
|
Int J Cancer
|
2007
|
0.82
|
|
108
|
Radiofrequency ablation of lung cancer at Okayama University Hospital: a review of 10 years of experience.
|
Acta Med Okayama
|
2011
|
0.82
|
|
109
|
Percutaneous radiofrequency ablation of lung cancer presenting as ground-glass opacity.
|
Cardiovasc Intervent Radiol
|
2014
|
0.81
|
|
110
|
Preclinical evaluation of microRNA-34b/c delivery for malignant pleural mesothelioma.
|
Acta Med Okayama
|
2014
|
0.81
|
|
111
|
MicroRNA miR-34b/c enhances cellular radiosensitivity of malignant pleural mesothelioma cells.
|
Anticancer Res
|
2012
|
0.81
|
|
112
|
Phrenic nerve injury after radiofrequency ablation of lung tumors: retrospective evaluation of the incidence and risk factors.
|
J Vasc Interv Radiol
|
2012
|
0.81
|
|
113
|
Use of a vessel sealing system versus conventional electrocautery for lung parenchymal resection: a comparison of the clinicopathological outcomes in porcine lungs.
|
Surg Today
|
2013
|
0.81
|
|
114
|
Bronchiolitis obliterans organizing pneumonia after radiofrequency ablation of lung cancer: report of three cases.
|
J Vasc Interv Radiol
|
2012
|
0.81
|
|
115
|
Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells.
|
Cancer Sci
|
2011
|
0.81
|
|
116
|
Influence of radiofrequency ablation of lung cancer on pulmonary function.
|
Cardiovasc Intervent Radiol
|
2011
|
0.81
|
|
117
|
Percutaneous computed tomography-guided lung biopsy and pleural dissemination: an assessment by intraoperative pleural lavage cytology.
|
Cancer
|
2009
|
0.81
|
|
118
|
A novel strategy for treatment of metastatic pulmonary tumors: radiofrequency ablation in conjunction with surgery.
|
J Thorac Oncol
|
2008
|
0.80
|
|
119
|
Early effects of the ex vivo evaluation system on graft function after swine lung transplantation.
|
Eur J Cardiothorac Surg
|
2011
|
0.80
|
|
120
|
Anti-tumor effect of bisphosphonate (YM529) on non-small cell lung cancer cell lines.
|
BMC Cancer
|
2007
|
0.80
|
|
121
|
Low frequency of drug-resistant virus did not affect the therapeutic efficacy in daclatasvir plus asunaprevir therapy in patients with chronic HCV genotype-1 infection.
|
Antivir Ther
|
2015
|
0.80
|
|
122
|
Surgical resection of a massive primary mediastinal liposarcoma using clamshell incision combined with lower median sternotomy: report of a case.
|
Ann Thorac Cardiovasc Surg
|
2013
|
0.80
|
|
123
|
Current status and potential of living-donor lobar lung transplantation.
|
Front Biosci
|
2008
|
0.80
|
|
124
|
Living-donor lobar lung transplantation for pulmonary complications after hematopoietic stem cell transplantation.
|
Transplantation
|
2008
|
0.79
|
|
125
|
Aberrant methylation of p21 gene in lung cancer and malignant pleural mesothelioma.
|
Acta Med Okayama
|
2011
|
0.79
|
|
126
|
Usefulness of cumulative smoking dose for identifying the EGFR mutation and patients with non-small-cell lung cancer for gefitinib treatment.
|
Cancer Sci
|
2009
|
0.79
|
|
127
|
STAT3 expression in activating EGFR-driven adenocarcinoma of the lung.
|
Lung Cancer
|
2012
|
0.79
|
|
128
|
Massive subcutaneous and mediastinal emphysema with little pneumothorax treated by surgery after pulmonary radiofrequency ablation.
|
Cardiovasc Intervent Radiol
|
2013
|
0.79
|
|
129
|
Infrequent existence of simian virus 40 large T antigen DNA in malignant mesothelioma in Japan.
|
Cancer Sci
|
2006
|
0.79
|
|
130
|
[Primary mediastinal lymphoma; a clinicopathologic case series].
|
Kyobu Geka
|
2012
|
0.78
|
|
131
|
A case of delayed massive hemothorax caused by the rupture of a pulmonary artery pseudoaneurysm after radiofrequency ablation of lung tumors.
|
Jpn J Clin Oncol
|
2012
|
0.78
|
|
132
|
Relationship between epidermal growth factor receptor gene mutations and the severity of adverse events by gefitinib in patients with advanced non-small cell lung cancer.
|
Lung Cancer
|
2006
|
0.78
|
|
133
|
Resection of the entire first rib for fibrous dysplasia using a combined posterior-transmanubrial approach.
|
Gen Thorac Cardiovasc Surg
|
2012
|
0.78
|
|
134
|
Adjuvant chemotherapy for completely resected non-small-cell lung cancer.
|
Acta Med Okayama
|
2009
|
0.78
|
|
135
|
Mutation analysis of the BRAF codon 599 in malignant pleural mesothelioma by enriched PCR-RFLP.
|
Oncol Rep
|
2004
|
0.78
|
|
136
|
Triplet chemotherapy with cisplatin, docetaxel, and irinotecan for patients with recurrent or refractory non-small cell lung cancer.
|
Acta Med Okayama
|
2010
|
0.78
|
|
137
|
Calcineurin inhibitor-related cholestasis complicating lung transplantation.
|
Ann Thorac Surg
|
2010
|
0.78
|
|
138
|
DNA methylation in lung cancer.
|
N Engl J Med
|
2008
|
0.78
|
|
139
|
Silenced expression of NFKBIA in lung adenocarcinoma patients with a never-smoking history.
|
Acta Med Okayama
|
2013
|
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