Published in Mol Biol Cell on March 02, 2005
The physiological significance of the cardiotonic steroid/ouabain-binding site of the Na,K-ATPase. Annu Rev Physiol (2010) 1.58
A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia. Am J Hum Genet (2007) 1.33
The Na-K-ATPase α₁β₁ heterodimer as a cell adhesion molecule in epithelia. Am J Physiol Cell Physiol (2012) 1.11
Function of FXYD proteins, regulators of Na, K-ATPase. J Bioenerg Biomembr (2005) 1.04
Module network inference from a cancer gene expression data set identifies microRNA regulated modules. PLoS One (2010) 1.02
Correlation of gene and protein structures in the FXYD family proteins. J Mol Biol (2005) 1.00
Down-regulation of FXYD3 expression in human lung cancers: its mechanism and potential role in carcinogenesis. Am J Pathol (2009) 0.87
Translocation of Pseudomonas aeruginosa from the intestinal tract is mediated by the binding of ExoS to an Na,K-ATPase regulator, FXYD3. Infect Immun (2010) 0.86
Identification of zebrafish Fxyd11a protein that is highly expressed in ion-transporting epithelium of the gill and skin and its possible role in ion homeostasis. Front Physiol (2010) 0.82
A link between FXYD3 (Mat-8)-mediated Na,K-ATPase regulation and differentiation of Caco-2 intestinal epithelial cells. Mol Biol Cell (2008) 0.81
FXYD3: A Promising Biomarker for Urothelial Carcinoma. Biomark Insights (2011) 0.79
FXYD2 and Na,K-ATPase expression in isolated human proximal tubular cells: disturbed upregulation on renal hypomagnesemia? J Membr Biol (2009) 0.78
Estrogen and tamoxifen up-regulate FXYD3 on breast cancer cells: assessing the differential roles of ER α and ZEB1. Springerplus (2015) 0.76
FXYD5: Na(+)/K(+)-ATPase Regulator in Health and Disease. Front Cell Dev Biol (2016) 0.75
Different Modulatory Mechanisms of Renal FXYD12 for Na(+)-K(+)-ATPase between Two Closely Related Medakas upon Salinity Challenge. Int J Biol Sci (2016) 0.75
Early vertebrate origin and diversification of small transmembrane regulators of cellular ion transport. J Physiol (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
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The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression. Genomics (2000) 2.79
Mechanisms of sodium pump regulation. Am J Physiol Cell Physiol (2000) 2.34
Transport and pharmacological properties of nine different human Na, K-ATPase isozymes. J Biol Chem (2000) 1.99
Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport properties. Proc Natl Acad Sci U S A (2002) 1.94
Purification and complete sequence determination of the major plasma membrane substrate for cAMP-dependent protein kinase and protein kinase C in myocardium. J Biol Chem (1991) 1.92
Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal control. Physiol Rev (2001) 1.85
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FXYD proteins: new tissue-specific regulators of the ubiquitous Na,K-ATPase. Sci STKE (2003) 1.50
Mat-8, a novel phospholemman-like protein expressed in human breast tumors, induces a chloride conductance in Xenopus oocytes. J Biol Chem (1995) 1.47
Oligomerization and maturation of Na,K-ATPase: functional interaction of the cytoplasmic NH2 terminus of the beta subunit with the alpha subunit. J Cell Biol (1996) 1.34
The gamma subunit modulates Na(+) and K(+) affinity of the renal Na,K-ATPase. J Biol Chem (1999) 1.30
Modulation of the Na,K-pump function by beta subunit isoforms. J Gen Physiol (1994) 1.28
The gamma subunit is a specific component of the Na,K-ATPase and modulates its transport function. EMBO J (1997) 1.28
Role of beta-subunit domains in the assembly, stable expression, intracellular routing, and functional properties of Na,K-ATPase. J Biol Chem (1998) 1.27
Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchor. EMBO J (2001) 1.24
CHIF, a member of the FXYD protein family, is a regulator of Na,K-ATPase distinct from the gamma-subunit. EMBO J (2001) 1.18
Up-regulated expression of the MAT-8 gene in prostate cancer and its siRNA-mediated inhibition of expression induces a decrease in proliferation of human prostate carcinoma cells. Int J Oncol (2004) 1.16
FXYD7 is a brain-specific regulator of Na,K-ATPase alpha 1-beta isozymes. EMBO J (2002) 1.11
Effects of inefficient cleavage of the signal sequence of HIV-1 gp 120 on its association with calnexin, folding, and intracellular transport. Proc Natl Acad Sci U S A (1996) 1.10
Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling. Cancer Res (2003) 1.08
Functional role and immunocytochemical localization of the gamma a and gamma b forms of the Na,K-ATPase gamma subunit. J Biol Chem (2001) 1.08
Structural and functional interaction sites between Na,K-ATPase and FXYD proteins. J Biol Chem (2004) 1.03
Role of the transmembrane and extracytoplasmic domain of beta subunits in subunit assembly, intracellular transport, and functional expression of Na,K-pumps. J Cell Biol (1993) 1.03
Immunochemical evidence for a transmembrane orientation of both the (Na+, K+)-ATPase subunits. Biochemistry (1981) 0.99
A functional interaction between CHIF and Na-K-ATPase: implication for regulation by FXYD proteins. Am J Physiol Renal Physiol (2002) 0.98
FXYD7, mapping of functional sites involved in endoplasmic reticulum export, association with and regulation of Na,K-ATPase. J Biol Chem (2004) 0.91
Modulation of Na,K-ATPase by the gamma subunit: studies with transfected cells and transmembrane mimetic peptides. J Biol Chem (2003) 0.88
Mouse mammary tumor virus superantigens and murine autoimmune gastritis. Gastroenterology (1994) 0.87
Structure-function relations of interactions between Na,K-ATPase, the gamma subunit, and corticosteroid hormone-induced factor. J Biol Chem (2003) 0.86
Determinants of topogenesis and glycosylation of type II membrane proteins. Analysis of Na,K-ATPase beta 1 AND beta 3 subunits by glycosylation mapping. J Biol Chem (2000) 0.86
FXYD proteins: new tissue-specific regulators of the ubiquitous Na,K-ATPase. Sci STKE (2003) 1.50
Phosphorylation of phospholemman (FXYD1) by protein kinases A and C modulates distinct Na,K-ATPase isozymes. J Biol Chem (2007) 1.23
Mouse GLUT9: evidences for a urate uniporter. Am J Physiol Renal Physiol (2009) 1.15
A third Na+-binding site in the sodium pump. Proc Natl Acad Sci U S A (2005) 1.14
Electrogenicity of Na,K- and H,K-ATPase activity and presence of a positively charged amino acid in the fifth transmembrane segment. J Biol Chem (2003) 1.12
FXYD7 is a brain-specific regulator of Na,K-ATPase alpha 1-beta isozymes. EMBO J (2002) 1.11
FXYD proteins reverse inhibition of the Na+-K+ pump mediated by glutathionylation of its beta1 subunit. J Biol Chem (2011) 1.07
Structural and functional interaction sites between Na,K-ATPase and FXYD proteins. J Biol Chem (2004) 1.03
The third sodium binding site of Na,K-ATPase is functionally linked to acidic pH-activated inward current. J Membr Biol (2007) 1.02
FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear. J Biol Chem (2007) 0.98
A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase. Hum Mol Genet (2007) 0.93
FXYD7, mapping of functional sites involved in endoplasmic reticulum export, association with and regulation of Na,K-ATPase. J Biol Chem (2004) 0.91
Structural and functional properties of two human FXYD3 (Mat-8) isoforms. J Biol Chem (2006) 0.91
New molecular determinants controlling the accessibility of ouabain to its binding site in human Na,K-ATPase alpha isoforms. Mol Pharmacol (2004) 0.88
Human nongastric H+-K+-ATPase: transport properties of ATP1al1 assembled with different beta-subunits. Am J Physiol Cell Physiol (2002) 0.88
Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase. J Biol Chem (2005) 0.87
Evolution of Na,K-ATPase beta m-subunit into a coregulator of transcription in placental mammals. Proc Natl Acad Sci U S A (2007) 0.84
A link between FXYD3 (Mat-8)-mediated Na,K-ATPase regulation and differentiation of Caco-2 intestinal epithelial cells. Mol Biol Cell (2008) 0.81
Two-dimensional Blue Native/sodium dodecyl sulfate gel electrophoresis for analysis of multimeric proteins in platelets. Electrophoresis (2005) 0.80
Dynamic expression of FXYD6 in the inner ear suggests a role of the protein in endolymph homeostasis and neuronal activity. Dev Dyn (2007) 0.80
Betam, a structural member of the X,K-ATPase beta subunit family, resides in the ER and does not associate with any known X,K-ATPase alpha subunit. Biochemistry (2002) 0.79
FXYD7, the first brain- and isoform-specific regulator of Na,K-ATPase: biosynthesis and function of its posttranslational modifications. Ann N Y Acad Sci (2003) 0.78
The muscle-specific beta m protein is functionally different from other members of the X,K-ATPase beta-subunit family. Ann N Y Acad Sci (2003) 0.78
[FXYD proteins: novel regulators of Na,K-ATPase]. Med Sci (Paris) (2006) 0.78
Prevalence and specificity of antigastric autoantibodies in adolescents infected with Helicobacter pylori. J Pediatr (2002) 0.77
Role of homologous ASP334 and GLU319 in human non-gastric H,K- and Na,K-ATPases in cardiac glycoside binding. Biochem Biophys Res Commun (2007) 0.77
Nongastric H,K-ATPase: structure and functional properties. Ann N Y Acad Sci (2003) 0.77
Na,K-ATPase alpha-beta subunit interactions in the transmembrane domain. Ann N Y Acad Sci (2003) 0.75
Inotropic activity of hydroindene amidinohydrazones. J Med Chem (2002) 0.75