Published in Mutat Res on January 25, 2005
A comprehensive catalogue of somatic mutations from a human cancer genome. Nature (2009) 24.27
Shining a light on xeroderma pigmentosum. J Invest Dermatol (2012) 2.33
Nonmelanoma skin cancer and risk for subsequent malignancy. J Natl Cancer Inst (2008) 2.08
Whole genome sequencing of matched primary and metastatic acral melanomas. Genome Res (2011) 1.90
Xeroderma pigmentosum. Orphanet J Rare Dis (2011) 1.62
UV signature mutations. Photochem Photobiol (2014) 1.52
UV radiation and the skin. Int J Mol Sci (2013) 1.37
DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene. Proc Natl Acad Sci U S A (2005) 1.15
Fanconi anemia proteins and endogenous stresses. Mutat Res (2009) 1.11
Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice. J Invest Dermatol (2011) 1.11
Patterns and processes of somatic mutations in nine major cancers. BMC Med Genomics (2014) 1.08
Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB-induced skin carcinogenesis. Oncogene (2009) 1.05
Vitamin D and the skin: Physiology and pathophysiology. Rev Endocr Metab Disord (2012) 1.03
Vitamin D and the skin. J Bone Miner Metab (2010) 1.03
Genome-wide analysis of mutations in mutant lineages selected following fast-neutron irradiation mutagenesis of Arabidopsis thaliana. Genome Res (2012) 1.01
The genomic landscape of childhood and adolescent melanoma. J Invest Dermatol (2014) 0.99
The vitamin D receptor: a tumor suppressor in skin. Discov Med (2011) 0.98
Genomic analysis of metastatic cutaneous squamous cell carcinoma. Clin Cancer Res (2015) 0.96
Genetics of melanoma. Front Genet (2013) 0.91
The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D). Acta Neuropathol Commun (2013) 0.90
Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma. Oncogene (2011) 0.88
Protective actions of vitamin D in UVB induced skin cancer. Photochem Photobiol Sci (2012) 0.88
Protective role of vitamin D signaling in skin cancer formation. J Steroid Biochem Mol Biol (2012) 0.87
A novel POLH mutation causes XP-V disease and XP-V tumor proneness may involve imbalance of numerous DNA polymerases. Oncol Lett (2013) 0.80
The protective role of vitamin d signaling in non-melanoma skin cancer. Cancers (Basel) (2013) 0.79
Xeroderma pigmentosum: man deprived of his right to light. ScientificWorldJournal (2013) 0.77
Six genes associated with the clinical phenotypes of individuals with deficient and proficient DNA repair. Transl Oncogenomics (2008) 0.75
Unexpected UVR and non-UVR mutation burden in some acral and cutaneous melanomas. Lab Invest (2017) 0.75
Diagnosis of Xeroderma Pigmentosum Groups A and C by Detection of Two Prevalent Mutations in West Algerian Population: A Rapid Genotyping Tool for the Frequent XPC Mutation c.1643_1644delTG. Biomed Res Int (2016) 0.75
Chemical excitation of electrons: A dark path to melanoma. DNA Repair (Amst) (2016) 0.75
Diagnosis of Xeroderma Pigmentosum and Related DNA Repair-Deficient Cutaneous Diseases. Curr Med Lit Dermatol (2008) 0.75
Hydrogen/Deuterium Exchange Reflects Binding of Human Centrin 2 to Ca(2+) and Xeroderma Pigmentosum Group C Peptide: An Example of EX1 Kinetics. Int J Mass Spectrom (2012) 0.75
Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity. Oncotarget (2016) 0.75
DNA Mutations May Not Be the Cause of Cancer. Oncol Ther (2017) 0.75
ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer. Clin Cancer Res (2005) 3.44
Gene expression profiling of primary cutaneous melanoma and clinical outcome. J Natl Cancer Inst (2006) 3.17
UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair. Cell (2003) 2.41
Transcription-coupled nucleotide excision repair as a determinant of cisplatin sensitivity of human cells. Cancer Res (2002) 2.09
TP53 mutations in human skin cancers. Hum Mutat (2003) 2.07
Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. DNA Repair (Amst) (2008) 2.02
ERCC2/XPD gene polymorphisms and cancer risk. Mutagenesis (2002) 1.65
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Proc Natl Acad Sci U S A (2002) 1.63
A prevalent mutation with founder effect in xeroderma pigmentosum group C from north Africa. J Invest Dermatol (2010) 1.61
DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination. J Exp Med (2004) 1.59
DNA repair: from molecular mechanism to human disease. DNA Repair (Amst) (2006) 1.56
Role of DNA polymerase eta in the UV mutation spectrum in human cells. J Biol Chem (2003) 1.53
Skin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1. Clin Cancer Res (2011) 1.52
XPD mutations prevent TFIIH-dependent transactivation by nuclear receptors and phosphorylation of RARalpha. Cell (2002) 1.51
Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743. Proc Natl Acad Sci U S A (2007) 1.43
ERCC2 /XPD gene polymorphisms and lung cancer: a HuGE review. Am J Epidemiol (2005) 1.41
Sonic hedgehog signaling in basal cell carcinomas. Cancer Lett (2004) 1.40
Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line. DNA Repair (Amst) (2008) 1.40
DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract. Int J Cancer (2004) 1.37
Human DNA polymerase iota protects cells against oxidative stress. EMBO J (2008) 1.31
Reduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients. Carcinogenesis (2005) 1.30
Polymorphism discovery in 62 DNA repair genes and haplotype associations with risks for lung and head and neck cancers. Carcinogenesis (2007) 1.27
A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage. Proc Natl Acad Sci U S A (2009) 1.26
The DNA repair genes XPB and XPD defend cells from retroviral infection. Proc Natl Acad Sci U S A (2006) 1.18
Ocular manifestations in the inherited DNA repair disorders. Surv Ophthalmol (2003) 1.16
Deletion of 5' sequences of the CSB gene provides insight into the pathophysiology of Cockayne syndrome. Eur J Hum Genet (2008) 1.12
Transcription through 8-oxoguanine in DNA repair-proficient and Csb(-)/Ogg1(-) DNA repair-deficient mouse embryonic fibroblasts is dependent upon promoter strength and sequence context. Mutagenesis (2007) 1.08
Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication. Proc Natl Acad Sci U S A (2003) 1.07
Hypothetical role of RNA damage avoidance in preventing human disease. Mutat Res (2005) 1.05
Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium. Carcinogenesis (2012) 1.05
Irofulven cytotoxicity depends on transcription-coupled nucleotide excision repair and is correlated with XPG expression in solid tumor cells. Clin Cancer Res (2004) 1.05
Analysis of skin cancer risk factors in immunosuppressed renal transplant patients shows high levels of UV-specific tandem CC to TT mutations of the p53 gene. Carcinogenesis (2006) 1.04
Trabectedin and its C subunit modified analogue PM01183 attenuate nucleotide excision repair and show activity toward platinum-resistant cells. Mol Cancer Ther (2011) 1.02
Development of new EBV-based vectors for stable expression of small interfering RNA to mimick human syndromes: application to NER gene silencing. Mol Cancer Res (2005) 1.02
Identification of new RECQL4 mutations in Caucasian Rothmund-Thomson patients and analysis of sensitivity to a wide range of genotoxic agents. Mutat Res (2008) 1.02
Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells. PLoS Genet (2009) 1.00
Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas. Mol Oncol (2008) 1.00
A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta. J Immunol (2009) 0.99
Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. Carcinogenesis (2009) 0.98
A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines. Pigment Cell Melanoma Res (2012) 0.97
Transcriptional profiles of unirradiated or UV-irradiated human cells expressing either the cancer-prone XPB/CS allele or the noncancer-prone XPB/TTD allele. Oncogene (2005) 0.97
The genetics of the hereditary xeroderma pigmentosum syndrome. Biochimie (2002) 0.95
CPDs and 6-4PPs play different roles in UV-induced cell death in normal and NER-deficient human cells. DNA Repair (Amst) (2007) 0.94
Mutations in the C7orf11 (TTDN1) gene in six nonphotosensitive trichothiodystrophy patients: no obvious genotype-phenotype relationships. Hum Mutat (2007) 0.93
Trichothiodystrophy fibroblasts are deficient in the repair of ultraviolet-induced cyclobutane pyrimidine dimers and (6-4)photoproducts. J Invest Dermatol (2004) 0.93
BMP2 and BMP6 control p57(Kip2) expression and cell growth arrest/terminal differentiation in normal primary human epidermal keratinocytes. Cell Signal (2006) 0.93
Influence of irofulven, a transcription-coupled repair-specific antitumor agent, on RNA polymerase activity, stability and dynamics in living mammalian cells. J Cell Sci (2008) 0.91
Differential repair of the two major UV-induced photolesions in trichothiodystrophy fibroblasts. Cancer Res (2004) 0.91
A new XPC gene splicing mutation has lead to the highest worldwide prevalence of xeroderma pigmentosum in black Mahori patients. DNA Repair (Amst) (2011) 0.90
Novel XPG (ERCC5) mutations affect DNA repair and cell survival after ultraviolet but not oxidative stress. Hum Mutat (2013) 0.90
UVB-induced mutations in human key gatekeeper genes governing signalling pathways and consequences for skin tumourigenesis. Photochem Photobiol Sci (2003) 0.89
Complementation of the DNA repair deficiency in human xeroderma pigmentosum group a and C cells by recombinant adenovirus-mediated gene transfer. Hum Gene Ther (2002) 0.89
Variants in DNA double-strand break repair and DNA damage-response genes and susceptibility to lung and head and neck cancers. Int J Cancer (2008) 0.89
Genetic correction of DNA repair-deficient/cancer-prone xeroderma pigmentosum group C keratinocytes. Hum Gene Ther (2003) 0.89
New clinico-genetic classification of trichothiodystrophy. Am J Med Genet A (2009) 0.88
New founder germline mutations of CDKN2A in melanoma-prone families and multiple primary melanoma development in a patient receiving levodopa treatment. Genes Chromosomes Cancer (2007) 0.88
Preclinical corrective gene transfer in xeroderma pigmentosum human skin stem cells. Mol Ther (2011) 0.88
Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome. Cell (2005) 0.87
Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions. Cancer Lett (2011) 0.86
Xeroderma pigmentosum: from symptoms and genetics to gene-based skin therapy. Cells Tissues Organs (2004) 0.85
Safe selection of genetically manipulated human primary keratinocytes with very high growth potential using CD24. Mol Ther (2007) 0.85
Significantly high levels of ultraviolet-specific mutations in the smoothened gene in basal cell carcinomas from DNA repair-deficient xeroderma pigmentosum patients. Cancer Res (2002) 0.85
Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™. PLoS One (2013) 0.84
Effect of the anti-neoplastic drug doxorubicin on XPD-mutated DNA repair-deficient human cells. DNA Repair (Amst) (2009) 0.82
Molecular responses to photogenotoxic stress induced by the antibiotic lomefloxacin in human skin cells: from DNA damage to apoptosis. J Invest Dermatol (2003) 0.82
Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients. Hum Mutat (2009) 0.82
Functional analysis of novel sonic hedgehog gene mutations identified in basal cell carcinomas from xeroderma pigmentosum patients. Cancer Res (2004) 0.81
Expression profiling of melanoma cell lines: in search of a progression-related molecular signature. Future Oncol (2007) 0.81
Fanconi anemia C gene product regulates expression of genes involved in differentiation and inflammation. Oncogene (2004) 0.81
Ultraviolet irradiation represses PATCHED gene transcription in human epidermal keratinocytes through an activator protein-1-dependent process. Cancer Res (2004) 0.81
Efficient repair of cyclobutane pyrimidine dimers at mutational hot spots is restored in complemented Xeroderma pigmentosum group C and trichothiodystrophy/xeroderma pigmentosum group D cells. J Mol Biol (2003) 0.81
Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling. Mutat Res (2007) 0.80
Photogenotoxicity of mammalian cells: a review of the different assays for in vitro testing. Photochem Photobiol (2002) 0.80
Oxidative stress in cancer prone xeroderma pigmentosum fibroblasts. Real-time and single cell monitoring of superoxide and nitric oxide production with microelectrodes. Carcinogenesis (2003) 0.80
Effects of camptothecin on double-strand break repair by non-homologous end-joining in DNA mismatch repair-deficient human colorectal cancer cell lines. Nucleic Acids Res (2005) 0.80
Reconstruction of DNA repair-deficient xeroderma pigmentosum skin in vitro: a model to study hypersensitivity to UV light. Photochem Photobiol (2005) 0.80
The NER proteins XPC and CSB, but not ERCC1, regulate the sensitivity to the novel DNA binder S23906: implications for recognition and repair of antitumor alkylators. Biochem Pharmacol (2010) 0.80
Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients. DNA Repair (Amst) (2008) 0.80
Molecular mechanisms of UV-induced mutations as revealed by the study of DNA polymerase eta in human cells. Res Microbiol (2002) 0.79
DNA damage and mutations induced by arachidonic acid peroxidation. Biochemistry (2003) 0.79
Effect of cell confluence on ultraviolet light apoptotic responses in DNA repair deficient cells. Mutat Res (2003) 0.79
Correlation of phenotype/genotype in a cohort of 23 xeroderma pigmentosum-variant patients reveals 12 new disease-causing POLH mutations. Hum Mutat (2014) 0.78
Defective transcription/repair factor IIH recruitment to specific UV lesions in trichothiodystrophy syndrome. Cancer Res (2008) 0.78
Prevalence of human papillomavirus in skin tumors from repair deficient xeroderma pigmentosum patients. Cancer Lett (2006) 0.78
CPD-photolyase adenovirus-mediated gene transfer in normal and DNA-repair-deficient human cells. J Cell Sci (2004) 0.77
Transcription-coupled repair of 8-oxoguanine in human cells and its deficiency in some DNA repair diseases. Biochimie (2003) 0.77
Mutagenic fingerprint of ozone in human cells. DNA Repair (Amst) (2002) 0.76
Adenovirus mediated transduction of the human DNA polymerase eta cDNA. DNA Repair (Amst) (2006) 0.76
Genetic reversion of inherited skin disorders. Mutat Res (2002) 0.76
Transcription-coupled repair of 8-oxoguanine in human cells. Methods Enzymol (2002) 0.75
DNA repair pathways and associated human diseases. Biochimie (2003) 0.75
Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus. Cancer Gene Ther (2005) 0.75
Adenovirus-mediated anti insulin-like growth factor I gene transfer for the treatment of hepatocellular carcinoma. Anticancer Res (2003) 0.75
Complementation assays adapted for DNA repair-deficient keratinocytes. Methods Mol Biol (2006) 0.75
2nd German-French DNA repair meeting - DNA damage and repair in ageing and degenerative diseases, Konstanz, Germany, September 20-23, 2009. Mech Ageing Dev (2010) 0.75
Resistance to ultraviolet-induced apoptosis in DNA repair deficient growth arrested human fibroblasts is not related to recovery from RNA transcription blockage. Mutat Res (2007) 0.75