Published in J Allergy Clin Immunol on March 01, 2005
Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more. Br J Pharmacol (2007) 2.35
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Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction. Br J Pharmacol (2007) 1.49
Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J Exp Med (2006) 1.25
New insights into innate immune mechanisms underlying allergenicity. Mucosal Immunol (2009) 1.23
Tissue factor as an initiator of coagulation and inflammation in the lung. Crit Care (2008) 1.22
Mucosal sensitization to German cockroach involves protease-activated receptor-2. Respir Res (2010) 1.15
Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR2. Am J Physiol Lung Cell Mol Physiol (2011) 1.10
Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4. Respir Res (2009) 1.05
β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway. Proc Natl Acad Sci U S A (2012) 1.03
beta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2. J Biol Chem (2010) 1.01
Protease-activated receptors and prostaglandins in inflammatory lung disease. Br J Pharmacol (2009) 1.00
Suppression of pancreatitis-related allodynia/hyperalgesia by proteinase-activated receptor-2 in mice. Br J Pharmacol (2006) 0.96
Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cell activation in vivo. Immunology (2009) 0.95
Airway delivery of soluble factors from plastic-adherent bone marrow cells prevents murine asthma. Am J Respir Cell Mol Biol (2011) 0.95
Hypersensitivity of pulmonary chemosensitive neurons induced by activation of protease-activated receptor-2 in rats. J Physiol (2006) 0.94
Respiratory tract allergic disease and atopy: experimental evidence for a fungal infectious etiology. Med Mycol (2010) 0.94
Serine protease activity of Cur l 1 from Curvularia lunata augments Th2 response in mice. J Clin Immunol (2008) 0.90
German cockroach frass proteases modulate the innate immune response via activation of protease-activated receptor-2. J Innate Immun (2010) 0.90
Effect of protease-activated receptor 2 activation on single TRPV1 channel activities in rat vagal pulmonary sensory neurons. Exp Physiol (2009) 0.88
Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice. Parasitol Res (2007) 0.88
Tolerizing allergic responses in the lung. Mucosal Immunol (2010) 0.88
Alveolar macrophages play a key role in cockroach-induced allergic inflammation via TNF-α pathway. PLoS One (2012) 0.87
Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cells. Respir Res (2014) 0.85
Role for β-arrestin in mediating paradoxical β2AR and PAR2 signaling in asthma. Curr Opin Pharmacol (2014) 0.84
Inhibition of airway epithelial-to-mesenchymal transition and fibrosis by kaempferol in endotoxin-induced epithelial cells and ovalbumin-sensitized mice. Lab Invest (2013) 0.84
Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling. Immunology (2007) 0.84
Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation. Pflugers Arch (2011) 0.82
Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma. Immunology (2015) 0.82
Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice. PLoS One (2014) 0.81
Role of Allergen Source-Derived Proteases in Sensitization via Airway Epithelial Cells. J Allergy (Cairo) (2012) 0.80
Rac2 is involved in bleomycin-induced lung inflammation leading to pulmonary fibrosis. Respir Res (2014) 0.80
Proteinases as molecular adjuvants in allergic airway disease. Biochim Biophys Acta (2011) 0.79
Atopic March from Atopic Dermatitis to Asthma-Like Lesions in NC/Nga Mice Is Accelerated or Aggravated by Neutralization of Stratum Corneum but Partially Inhibited by Acidification. J Invest Dermatol (2015) 0.78
House dust mite potentiates capsaicin-evoked Ca2+ transients in mouse pulmonary sensory neurons via activation of protease-activated receptor-2. Exp Physiol (2011) 0.77
Increased Protease-Activated Receptor-2 (PAR-2) Expression on CD14++CD16+ Peripheral Blood Monocytes of Patients with Severe Asthma. PLoS One (2015) 0.76
Role of estrogen receptor- α in an experimental model of bronchial asthma. Iran Biomed J (2010) 0.76
A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca2+-regulated ion conductance. Am J Physiol Cell Physiol (2014) 0.75
Bronchoprotection and bronchorelaxation in asthma: New targets, and new ways to target the old ones. Pharmacol Ther (2016) 0.75
Reply: Protease Plays a Role in Ragweed Pollen-Induced Neutrophil Recruitment and Epithelial Barrier Disruption. Am J Respir Cell Mol Biol (2017) 0.75
Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A (2011) 4.91
Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice. Am J Respir Crit Care Med (2008) 2.39
The functional significance behind expressing two IL-8 receptor types on PMN. J Leukoc Biol (2009) 1.81
A multifocal electroretinogram model predicting the development of diabetic retinopathy. Prog Retin Eye Res (2006) 1.65
A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis. J Biol Chem (2003) 1.64
Live Lactobacillus rhamnosus [corrected] is essential for the inhibitory effect on tumor necrosis factor alpha-induced interleukin-8 expression. Infect Immun (2004) 1.64
Atrial fibrillatory wave characteristics on surface electrogram: ECG to ECG repeatability over twenty-four hours in clinically stable patients. J Cardiovasc Electrophysiol (2004) 1.57
Unique autonomic profile of the pulmonary veins and posterior left atrium. J Am Coll Cardiol (2007) 1.56
Targeted nonviral gene-based inhibition of Gα(i/o)-mediated vagal signaling in the posterior left atrium decreases vagal-induced atrial fibrillation. Heart Rhythm (2011) 1.48
Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium-dependent potassium channel opening. J Cell Mol Med (2009) 1.44
Assessment of parasympathetic reactivation after exercise. Am J Physiol Heart Circ Physiol (2006) 1.44
High-resolution electrical mapping of depolarization and repolarization alternans in an ischemic dog model. Am J Physiol Heart Circ Physiol (2009) 1.43
Frequency gradients during two different forms of fibrillation in the canine atria. Heart Rhythm (2007) 1.38
Proteinase-activated receptor-2 promotes allergic sensitization to an inhaled antigen through a TNF-mediated pathway. J Immunol (2007) 1.20
Communication between gastrointestinal bacteria and the nervous system. Curr Opin Pharmacol (2012) 1.15
Early repolarization associated with ventricular arrhythmias in patients with chronic coronary artery disease. Circ Arrhythm Electrophysiol (2010) 1.07
Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation. J Immunol (2011) 1.07
Opposing effects of short- and long-term stress on airway inflammation. Am J Respir Crit Care Med (2003) 1.06
Synergistic enhancement of antitumor immunity with adoptively transferred tumor-specific CD4+ and CD8+ T cells and intratumoral lymphotactin transgene expression. Cancer Res (2002) 1.05
Ultrastructural and cellular basis for the development of abnormal myocardial mechanics during the transition from hypertension to heart failure. Am J Physiol Heart Circ Physiol (2013) 1.05
Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation. Toxicol Lett (2008) 1.05
The endothelium in health and disease--a target for therapeutic intervention. J Smooth Muscle Res (2003) 1.03
β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway. Proc Natl Acad Sci U S A (2012) 1.03
Tolerogenic dendritic cells induce CD4+CD25hiFoxp3+ regulatory T cell differentiation from CD4+CD25-/loFoxp3- effector T cells. J Immunol (2010) 1.02
The vagus nerve modulates CD4+ T cell activity. Brain Behav Immun (2009) 1.01
Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin Biochem (2007) 1.00
Spatiotemporal characterization of atrial activation in persistent human atrial fibrillation: multisite electrogram analysis and surface electrocardiographic correlations--a pilot study. Heart Rhythm (2008) 1.00
The role of stress in asthma: insight from studies on the effect of acute and chronic stressors in models of airway inflammation. Ann N Y Acad Sci (2006) 1.00
Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2. J Pharmacol Exp Ther (2002) 0.99
Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene. Immunology (2003) 0.97
Atrial fibrillation and waveform characterization. A time domain perspective in the surface ECG. IEEE Eng Med Biol Mag (2007) 0.96
House dust mite interactions with airway epithelium: role in allergic airway inflammation. Curr Allergy Asthma Rep (2013) 0.95
Airway delivery of soluble factors from plastic-adherent bone marrow cells prevents murine asthma. Am J Respir Cell Mol Biol (2011) 0.95
Analysis of the gene expression profiles of immature versus mature bone marrow-derived dendritic cells using DNA arrays. Biochem Biophys Res Commun (2002) 0.94
Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation. Cardiovasc Res (2009) 0.93
Induction of type 2 T helper cell allergen tolerance by IL-10-differentiated regulatory dendritic cells. Am J Respir Cell Mol Biol (2009) 0.92
Left atrial flow velocity distribution and flow coherence using four-dimensional FLOW MRI: a pilot study investigating the impact of age and Pre- and Postintervention atrial fibrillation on atrial hemodynamics. J Magn Reson Imaging (2013) 0.92
Bacteroides fragilis polysaccharide A is necessary and sufficient for acute activation of intestinal sensory neurons. Nat Commun (2013) 0.91
Neural substrate for atrial fibrillation: implications for targeted parasympathetic blockade in the posterior left atrium. Am J Physiol Heart Circ Physiol (2007) 0.90
Direct in vivo evidence of CD4+ T cell requirement for CTL response and memory via pMHC-I targeting and CD40L signaling. J Leukoc Biol (2012) 0.90
DNA microarray analysis of the gene expression profiles of naïve versus activated tumor-specific T cells. Life Sci (2002) 0.89
A novel ELR-CXC chemokine antagonist reduces intestinal ischemia reperfusion-induced mortality, and local and remote organ injury. J Surg Res (2009) 0.89
Clinical characteristics and prevalence of early repolarization associated with ventricular arrhythmias following acute ST-elevation myocardial infarction. Am J Cardiol (2012) 0.87
Comparison of induced versus natural regulatory T cells of the same TCR specificity for induction of tolerance to an environmental antigen. J Immunol (2013) 0.87
ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels. J Immunol (2009) 0.86
Relationship between pattern of occurrence of atrial fibrillation and surface electrocardiographic fibrillatory wave characteristics. Heart Rhythm (2004) 0.86
G31P, an antagonist against CXC chemokine receptors 1 and 2, inhibits growth of human prostate cancer cells in nude mice. Tohoku J Exp Med (2012) 0.86
Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat. Am J Physiol Heart Circ Physiol (2013) 0.85
Preliminary observations on expression of transforming growth factors beta1 and beta3 in equine full-thickness skin wounds healing normally or with exuberant granulation tissue. Vet Surg (2002) 0.85
Fucosylated but not sialylated milk oligosaccharides diminish colon motor contractions. PLoS One (2013) 0.85
Identification by mass spectroscopy of F4ac-fimbrial-binding proteins in porcine milk and characterization of lactadherin as an inhibitor of F4ac-positive Escherichia coli attachment to intestinal villi in vitro. Dev Comp Immunol (2005) 0.84
Identification of lipopolysaccharide-binding proteins in porcine milk. Can J Vet Res (2006) 0.84
Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation. Allergy Asthma Clin Immunol (2011) 0.84
Mast cell-fibroblast interactions induce matrix metalloproteinase-9 release from fibroblasts: role for IgE-mediated mast cell activation. J Immunol (2008) 0.84
Blockade of neutrophil responses in aspiration pneumonia via ELR-CXC chemokine antagonism does not predispose to airway bacterial outgrowth. Pulm Pharmacol Ther (2009) 0.83
Combined CXCR1/CXCR2 antagonism decreases radiation-induced alveolitis in the mouse. Radiat Res (2011) 0.83
Persistent sympathoexcitation long after submaximal exercise in subjects with and without coronary artery disease. Am J Physiol Heart Circ Physiol (2011) 0.83
The effect of early-life stress on airway inflammation in adult mice. Neuroimmunomodulation (2010) 0.83
Contribution of fibrosis and the autonomic nervous system to atrial fibrillation electrograms in heart failure. Circ Arrhythm Electrophysiol (2012) 0.82
Induction of prolonged asthma tolerance by IL-10-differentiated dendritic cells: differential impact on airway hyperresponsiveness and the Th2 immunoinflammatory response. J Immunol (2012) 0.82
CXCL8((3-73))K11R/G31P antagonizes ligand binding to the neutrophil CXCR1 and CXCR2 receptors and cellular responses to CXCL8/IL-8. Biochem Biophys Res Commun (2002) 0.82
Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation. Pflugers Arch (2011) 0.82
A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH2, induces protease release from mast cells: role in TNF degradation. BMC Pharmacol (2004) 0.82
A Lactobacillus rhamnosus strain induces a heme oxygenase dependent increase in Foxp3+ regulatory T cells. PLoS One (2012) 0.82
Dentin matrix protein-1 activates dental pulp fibroblasts. J Endod (2011) 0.82
PAR-2 elicits afferent arteriolar vasodilation by NO-dependent and NO-independent actions. Am J Physiol Renal Physiol (2002) 0.81
Hormonal and metabolic responses to a resistance exercise protocol in lean children, obese children and lean adults. Pediatr Exerc Sci (2014) 0.80
Detection of cardiovascular autonomic neuropathy using exercise testing in patients with type 2 diabetes mellitus. J Diabetes Complications (2012) 0.80
Fractionation of swine barn dust and assessment of its impact on the respiratory tract following repeated airway exposure. J Toxicol Environ Health A (2010) 0.80
Velocity quantification by electrocardiography-gated phase contrast magnetic resonance imaging in patients with cardiac arrhythmia: a simulation study based on real time transesophageal echocardiography data in atrial fibrillation. J Comput Assist Tomogr (2015) 0.80
Should we target allergen protease activity to decrease the burden of allergic airway inflammation? Inflamm Allergy Drug Targets (2008) 0.80
Association between allergic rhinitis and asthma in a Northern Alberta cohort. J Otolaryngol Head Neck Surg (2013) 0.80
Rac2 is involved in bleomycin-induced lung inflammation leading to pulmonary fibrosis. Respir Res (2014) 0.80
A prescription that addresses the decline of basic science education in medical school. Clin Invest Med (2014) 0.80
Iterative method to detect atrial activations and measure cycle length from electrograms during atrial fibrillation. IEEE Trans Biomed Eng (2014) 0.79
Temporal localization of immunoreactive transforming growth factor beta1 in normal equine skin and in full-thickness dermal wounds. Vet Surg (2002) 0.79
CXCL8((3-73))K11R/G31P antagonizes the neutrophil chemoattractants present in pasteurellosis and mastitis lesions and abrogates neutrophil influx into intradermal endotoxin challenge sites in vivo. Vet Immunol Immunopathol (2002) 0.79
Mast cell tryptase activates peripheral blood eosinophils to release granule-associated enzymes. Int Arch Allergy Immunol (2004) 0.78
Lactobacillus rhamnosus ingestion promotes innate host defense in an enteric parasitic infection. Clin Vaccine Immunol (2013) 0.78
A new protocol for high-yield purification of recombinant human CXCL8((3-72))K11R/G31P expressed in Escherichia coli. Protein Expr Purif (2008) 0.78
Natural killer cells in asthma. Front Immunol (2013) 0.78
Compound CVT-E002 attenuates allergen-induced airway inflammation and airway hyperresponsiveness, in vivo. Mol Nutr Food Res (2011) 0.78
Advances in dendritic cell-based vaccine of cancer. Cancer Biother Radiopharm (2002) 0.78
Recombinant human CXCL8(3-72)K11R/G31P regulates smooth muscle cell proliferation and migration through blockage of interleukin-8 receptor. IUBMB Life (2013) 0.77
Genetic engineering of a recombinant fusion protein possessing an antitumor antibody fragment and a TNF-alpha moiety. Methods Mol Biol (2003) 0.77
Left Atrial 4-Dimensional Flow Magnetic Resonance Imaging: Stasis and Velocity Mapping in Patients With Atrial Fibrillation. Invest Radiol (2016) 0.77
Recovery of heart rate variability and ventricular repolarization indices following exercise. Ann Noninvasive Electrocardiol (2012) 0.77
Hierarchical kernel mixture models for the prediction of AIDS disease progression using HIV structural gp120 profiles. BMC Genomics (2010) 0.77
CXCR1/CXCR2 antagonism is effective in pulmonary defense against Klebsiella pneumoniae infection. Biomed Res Int (2013) 0.76
QT-RR hysteresis is caused by differential autonomic states during exercise and recovery. Am J Physiol Heart Circ Physiol (2012) 0.76
Comparison of mechanomyographic sensors during incremental cycle ergometry for the quadriceps femoris. Muscle Nerve (2010) 0.76
Can gestational hypertension be modified by treating nocturnal airflow limitation? J Clin Sleep Med (2013) 0.76