Published in Chem Rev on March 01, 2005
Natural products version 2.0: connecting genes to molecules. J Am Chem Soc (2010) 3.06
The evolution of gene collectives: How natural selection drives chemical innovation. Proc Natl Acad Sci U S A (2008) 2.71
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis. BMC Syst Biol (2008) 1.84
Taxonomy, Physiology, and Natural Products of Actinobacteria. Microbiol Mol Biol Rev (2015) 1.36
The evolving role of chemical synthesis in antibacterial drug discovery. Angew Chem Int Ed Engl (2014) 1.05
Synthesis and SAR of 3,5-diamino-piperidine derivatives: novel antibacterial translation inhibitors as aminoglycoside mimetics. Bioorg Med Chem Lett (2006) 1.03
Asymmetric synthesis of diamine derivatives via sequential palladium and rhodium catalysis. J Am Chem Soc (2009) 0.94
Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands. Nucleic Acids Res (2008) 0.94
Inhibitory effects of archetypical nucleic acid ligands on the interactions of HIV-1 nucleocapsid protein with elements of Psi-RNA. Nucleic Acids Res (2006) 0.93
A modular approach to synthetic RNA binders of the hepatitis C virus internal ribosome entry site. Chembiochem (2010) 0.87
Noncovalent probes for the investigation of structure and dynamics of protein-nucleic acid assemblies: the case of NC-mediated dimerization of genomic RNA in HIV-1. Biopolymers (2009) 0.86
Lipid-modified aminoglycoside derivatives for in vivo siRNA delivery. Adv Mater (2013) 0.86
A model for the study of ligand binding to the ribosomal RNA helix h44. Nucleic Acids Res (2010) 0.84
1,3-Diazepanes of natural product-like complexity from cyanamide-induced rearrangement of epoxy-delta-lactams. Org Lett (2010) 0.82
Revisiting plus-strand DNA synthesis in retroviruses and long terminal repeat retrotransposons: dynamics of enzyme: substrate interactions. Viruses (2009) 0.80
Synthesis and reactivity of unique heterocyclic structures en route to substituted diamines. Org Lett (2011) 0.80
tRNAs as antibiotic targets. Int J Mol Sci (2014) 0.78
Aminoglycosides: molecular insights on the recognition of RNA and aminoglycoside mimics. Perspect Medicin Chem (2009) 0.77
Regio- and stereoselective synthesis of new diaminocyclopentanols. Beilstein J Org Chem (2014) 0.75
2-Deoxystreptamine Conjugates by Truncation-Derivatization of Neomycin. Pharmaceuticals (Basel) (2010) 0.75
Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors. Bioorg Med Chem Lett (2008) 0.75
Asymmetric stereodivergent strategy towards aminocyclitols. Chemistry (2014) 0.75
A review of patents (2011-2015) towards combating resistance to and toxicity of aminoglycosides. Medchemcomm (2015) 0.75
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition. Chem Commun (Camb) (2009) 2.72
Readily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells. Angew Chem Int Ed Engl (2010) 2.36
Bioconjugation with strained alkenes and alkynes. Acc Chem Res (2011) 1.89
Metal-free triazole formation as a tool for bioconjugation. Chembiochem (2007) 1.54
Azide: a unique dipole for metal-free bioorthogonal ligations. Chembiochem (2010) 1.40
Preventing thiol-yne addition improves the specificity of strain-promoted azide-alkyne cycloaddition. Bioconjug Chem (2012) 1.27
Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation. Chembiochem (2012) 1.25
Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro. J Mol Biol (2007) 1.21
Ligand effects of NHC-iridium catalysts for signal amplification by reversible exchange (SABRE). Chem Commun (Camb) (2013) 1.19
Protein modification by strain-promoted alkyne-nitrone cycloaddition. Angew Chem Int Ed Engl (2010) 1.17
Organocatalysed asymmetric Mannich reactions. Chem Soc Rev (2007) 1.08
Application of metal-free triazole formation in the synthesis of cyclic RGD-DTPA conjugates. Chembiochem (2008) 1.05
Plasma N-glycan profiling by mass spectrometry for congenital disorders of glycosylation type II. Clin Chem (2011) 1.05
Bioorthogonal labelling of biomolecules: new functional handles and ligation methods. Org Biomol Chem (2013) 1.04
Synthesis of isoxazoles by hypervalent iodine-induced cycloaddition of nitrile oxides to alkynes. Chem Commun (Camb) (2011) 1.04
Toward nanomolar detection by NMR through SABRE hyperpolarization. J Am Chem Soc (2014) 1.03
Targeting aberrant sialylation in cancer cells using a fluorinated sialic acid analog impairs adhesion, migration, and in vivo tumor growth. Mol Cancer Ther (2013) 1.01
Targeting of a CCK(2) receptor splice variant with (111)In-labelled cholecystokinin-8 (CCK8) and (111)In-labelled minigastrin. Eur J Nucl Med Mol Imaging (2007) 0.98
Conjugation of nucleosides and oligonucleotides by [3+2] cycloaddition. J Org Chem (2007) 0.93
Recent advances in enzymatic and chemical deracemisation of racemic compounds. Chem Soc Rev (2013) 0.93
In situ phosphine oxide reduction: a catalytic Appel reaction. Chemistry (2011) 0.92
Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors. Amino Acids (2010) 0.90
Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol (2013) 0.90
Expedient synthesis of triazole-linked glycosyl amino acids and peptides. Org Lett (2004) 0.90
A microfluidic high-resolution NMR flow probe. J Am Chem Soc (2009) 0.88
Strain-promoted oxidation-controlled cyclooctyne-1,2-quinone cycloaddition (SPOCQ) for fast and activatable protein conjugation. Bioconjug Chem (2015) 0.87
Quantitative trace analysis of complex mixtures using SABRE hyperpolarization. Angew Chem Int Ed Engl (2014) 0.86
Organophosphorus catalysis to bypass phosphine oxide waste. ChemSusChem (2013) 0.86
Fluorogenic peptide-based substrates for monitoring thrombin activity. ChemMedChem (2012) 0.86
Total synthesis of (+)-epiquinamide. Org Lett (2005) 0.86
Preparation and evaluation of glycosylated arginine-glycine-aspartate (RGD) derivatives for integrin targeting. Bioconjug Chem (2007) 0.85
Enzymatic glycosylation of triazole-linked GlcNAc/Glc-peptides: synthesis, stability and anti-HIV activity of triazole-linked HIV-1 gp41 glycopeptide C34 analogues. Chembiochem (2009) 0.85
Stabilized (111)in-labeled sCCK8 analogues for targeting CCK2-receptor positive tumors: synthesis and evaluation. Bioconjug Chem (2010) 0.85
Size dependent biodistribution and SPECT imaging of (111)In-labeled polymersomes. Bioconjug Chem (2012) 0.85
Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction. Chem Commun (Camb) (2005) 0.85
Viedma ripening: a reliable crystallisation method to reach single chirality. Chem Soc Rev (2015) 0.85
Amidopalladation of alkoxyallenes applied in the synthesis of an enantiopure 1-ethylquinolizidine frog alkaloid. J Am Chem Soc (2004) 0.84
Palladium-catalyzed synthesis of novel optically active tryptophan analogues. Org Lett (2003) 0.84
Synthetic applications of aliphatic unsaturated alpha-H-alpha-amino acids. Org Biomol Chem (2005) 0.84
Total synthesis and absolute stereochemistry of integric acid. J Org Chem (2009) 0.84
In-depth evaluation of the cycloaddition--retro-Diels--Alder reaction for in vivo targeting with [(111)In]-DTPA-RGD conjugates. Nucl Med Biol (2009) 0.83
Formation of optically active chromanes by catalytic asymmetric tandem oxa-Michael addition-Friedel-Crafts alkylation reactions. Org Biomol Chem (2003) 0.83
Enantioselective chemoenzymatic synthesis of trans-aziridines. J Org Chem (2009) 0.83
Synthesis of carbohydrates in a continuous flow reactor by immobilized phosphatase and aldolase. ChemSusChem (2012) 0.83
Clickable enzyme-linked immunosorbent assay. Biomacromolecules (2011) 0.82
Protein modification by strain-promoted alkyne-azide cycloaddition. Chembiochem (2011) 0.82
Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA. Nucleic Acids Res (2013) 0.82
Polymersome colloidosomes for enzyme catalysis in a biphasic system. Angew Chem Int Ed Engl (2012) 0.82
High-pressure entry into platencin. Angew Chem Int Ed Engl (2008) 0.81
Site-specific peptide and protein immobilization on surface plasmon resonance chips via strain-promoted cycloaddition. Lab Chip (2013) 0.81
A fast and activatable cross-linking strategy for hydrogel formation. Adv Mater (2014) 0.81
N,N-acetals as N-acyliminium ion precursors: synthesis and absolute stereochemistry of epiquinamide. Org Lett (2008) 0.81
A 4-deoxy analogue of N-acetyl-D-glucosamine inhibits heparan sulphate expression and growth factor binding in vitro. Exp Cell Res (2010) 0.81
Peptide-mediated blood-brain barrier transport of polymersomes. Angew Chem Int Ed Engl (2012) 0.81
Catalytic N-sulfonyliminium ion-mediated cyclizations to alpha-vinyl-substituted isoquinolines and beta-carbolines and applications in metathesis. J Org Chem (2005) 0.80
A sulfitylation-oxidation protocol for the preparation of sulfates. J Org Chem (2006) 0.80
The epithelial calcium channel TRPV5 is regulated differentially by klotho and sialidase. J Biol Chem (2013) 0.80
Tubular polymersomes: a cross-linker-induced shape transformation. J Am Chem Soc (2013) 0.80
Triphenylphosphine-catalysed amide bond formation between carboxylic acids and amines. Chem Commun (Camb) (2014) 0.80
CuAAC-mediated diversification of aminoglycoside-arginine conjugate mimics by non-reducing di- and trisaccharides. Carbohydr Res (2013) 0.79
Papain-specific activating esters in aqueous dipeptide synthesis. Chembiochem (2012) 0.79
A stereodivergent approach to substituted 4-hydroxypiperidines. J Org Chem (2002) 0.79
Flash chemistry extensively optimized: high-temperature Swern-Moffatt oxidation in an automated microreactor platform. Chem Asian J (2010) 0.79
Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters. Chembiochem (2011) 0.79
N-Terminal dual protein functionalization by strain-promoted alkyne-nitrone cycloaddition. Org Biomol Chem (2013) 0.78
Synthesis of spirohydantoins and spiro-2,5-diketopiperazines via resin-bound cyclic alpha,alpha-disubstituted alpha-amino esters. J Comb Chem (2006) 0.78
Oligonucleotide tagging for copper-free click conjugation. Molecules (2013) 0.78
Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria. Antimicrob Agents Chemother (2013) 0.78
Application of the π-accepting ability parameter of N-heterocyclic carbene ligands in iridium complexes for signal amplification by reversible exchange (SABRE). Dalton Trans (2015) 0.78
Aromatic A-ring analogues of orobanchol, new germination stimulants for seeds of parasitic weeds. Org Biomol Chem (2011) 0.77
Enantioselective chemoenzymatic synthesis of cis- and trans-2,5-disubstituted morpholines. J Org Chem (2010) 0.77