|
1
|
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.
|
Neurobiol Dis
|
2006
|
5.96
|
|
2
|
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
|
Proc Natl Acad Sci U S A
|
2004
|
4.76
|
|
3
|
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability.
|
Proc Natl Acad Sci U S A
|
2005
|
4.22
|
|
4
|
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.
|
Proc Natl Acad Sci U S A
|
2008
|
2.76
|
|
5
|
Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.
|
PLoS One
|
2009
|
2.23
|
|
6
|
L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system.
|
J Biol Chem
|
2003
|
2.12
|
|
7
|
Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1.
|
J Biol Chem
|
2009
|
1.71
|
|
8
|
Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1.
|
J Neurochem
|
2007
|
1.70
|
|
9
|
Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines.
|
J Neurochem
|
2003
|
1.32
|
|
10
|
Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization.
|
Brain Res Mol Brain Res
|
2005
|
1.18
|
|
11
|
Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease.
|
Neurosci Lett
|
2009
|
0.96
|
|
12
|
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease.
|
J Neurochem
|
2005
|
0.87
|