Published in Biochemistry (Mosc) on February 01, 2005
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest (2006) 3.34
Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chin Med (2007) 1.36
Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin defects syndrome. Am J Hum Genet (2006) 1.32
PERSISTENT TAPETAL CELL1 encodes a PHD-finger protein that is required for tapetal cell death and pollen development in rice. Plant Physiol (2011) 1.28
Caspase-2 mediated apoptotic and necrotic murine macrophage cell death induced by rough Brucella abortus. PLoS One (2009) 1.20
Membrane deformation under local pH gradient: mimicking mitochondrial cristae dynamics. Biophys J (2008) 1.15
Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease. Chem Biol Interact (2010) 1.10
Mitochondrial biogenesis and function in Arabidopsis. Arabidopsis Book (2008) 1.06
Mitochondrial protection by low doses of insulin-like growth factor- I in experimental cirrhosis. World J Gastroenterol (2008) 0.98
Naturally occurring triggers that induce apoptosis-like programmed cell death in Plasmodium berghei ookinetes. PLoS One (2010) 0.96
Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro. Parasit Vectors (2009) 0.96
DNA alteration and programmed cell death during ageing of sunflower seed. J Exp Bot (2011) 0.96
Role of oxidative stress and caspase 3 in CD47-mediated neuronal cell death. J Neurochem (2008) 0.94
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. Mol Cancer (2009) 0.94
Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis. Apoptosis (2010) 0.93
Neuroprotective and antioxidative effect of cactus polysaccharides in vivo and in vitro. Cell Mol Neurobiol (2009) 0.90
Towards a better monitoring of seed ageing under ex situ seed conservation. Conserv Physiol (2015) 0.90
Role of cagA-positive Helicobacter pylori on cell proliferation, apoptosis, and inflammation in biliary cells. Dig Dis Sci (2010) 0.88
Mechanisms of neutrophil death in human immunodeficiency virus-infected patients: role of reactive oxygen species, caspases and map kinase pathways. Clin Exp Immunol (2007) 0.87
Mitochondrial protein phosphorylation: instigator or target of lipotoxicity? Trends Endocrinol Metab (2009) 0.86
Ethanol influences on Bax translocation, mitochondrial membrane potential, and reactive oxygen species generation are modulated by vitamin E and brain-derived neurotrophic factor. Alcohol Clin Exp Res (2011) 0.86
Antiproliferative property of n-hexane and chloroform extracts of Anisomeles malabarica (L). R. Br. in HPV16-positive human cervical cancer cells. J Pharmacol Pharmacother (2012) 0.85
Identification of a putative mitochondrial RNA polymerase from Physarum polycephalum: characterization, expression, purification, and transcription in vitro. Curr Genet (2006) 0.84
Effects of Helicobacter pylori γ-glutamyltranspeptidase on apoptosis and inflammation in human biliary cells. Dig Dis Sci (2012) 0.84
Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats. J Transl Med (2011) 0.83
Anti-Trypanosoma cruzi activity of Pterodon pubescens seed oil: geranylgeraniol as the major bioactive component. Parasitol Res (2008) 0.82
Inhibition of p38 MAP kinase pathway induces apoptosis and prevents Epstein Barr virus reactivation in Raji cells exposed to lytic cycle inducing compounds. Mol Cancer (2009) 0.82
Necrotic Effect versus Apoptotic Nature of Camptothecin in Human Cervical Cancer Cells. Iran J Cancer Prev (2012) 0.82
Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway. Int J Endocrinol (2013) 0.81
Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines. World J Gastroenterol (2010) 0.81
Ginsenoside‑Rg5 induces apoptosis and DNA damage in human cervical cancer cells. Mol Med Rep (2014) 0.81
Antioxidant Activity and ROS-Dependent Apoptotic Effect of Scurrula ferruginea (Jack) Danser Methanol Extract in Human Breast Cancer Cell MDA-MB-231. PLoS One (2016) 0.81
Inhibition of mitochondria responsible for the anti-apoptotic effects of melatonin during ischemia-reperfusion. J Zhejiang Univ Sci B (2006) 0.80
Pyrroloquinoline Quinone Induces Cancer Cell Apoptosis via Mitochondrial-Dependent Pathway and Down-Regulating Cellular Bcl-2 Protein Expression. J Cancer (2014) 0.79
Responses to high seawater temperatures in zooxanthellate octocorals. PLoS One (2013) 0.78
Ethanol influences on Bax associations with mitochondrial membrane proteins in neonatal rat cerebellum. Dev Neurobiol (2012) 0.78
Incorporation of branched-chain fatty acid into cellular lipids and caspase-independent apoptosis in human breast cancer cell line, SKBR-3. Lipids Health Dis (2005) 0.78
The larvicidal activity of Agave sisalana against L4 larvae of Aedes aegypti is mediated by internal necrosis and inhibition of nitric oxide production. Parasitol Res (2014) 0.77
Mechanisms of Biliary Damage. J Cell Death (2010) 0.77
A structurally simplified analogue of geldanamycin exhibits neuroprotective activity. ACS Med Chem Lett (2013) 0.76
Ethanolic extract of Tulipa edulis Bak induces apoptosis in SGC-7901 human gastric carcinoma cells via the mitochondrial signaling pathway. Oncol Lett (2015) 0.76
An optimized pyrimidinol multifunctional radical quencher. ACS Med Chem Lett (2013) 0.76
Winter wheat cells subjected to freezing temperature undergo death process with features of programmed cell death. Protoplasma (2013) 0.76
Synergistic effects of isomorellin and forbesione with doxorubicin on apoptosis induction in human cholangiocarcinoma cell lines. Cancer Cell Int (2014) 0.76
Dopaminochrome induces caspase-independent apoptosis in the mesencephalic cell line, MN9D. J Neurochem (2012) 0.76
In vitro Anti-Proliferative Effect of Tephrosia purpurea on Human Hepatocellular Carcinoma Cells. Pharmacogn Mag (2017) 0.75
Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin. Sci Rep (2017) 0.75
Lipidomics analysis of follicular fluid by ESI-MS reveals potential biomarkers for ovarian endometriosis. J Assist Reprod Genet (2015) 0.75
Mechanisms of Biliary Damage. J Cell Death (2010) 0.75
Identification of Mitochondrial Genome-Encoded Small RNAs Related to Egg Deterioration Caused by Postovulatory Aging in Rainbow Trout. Mar Biotechnol (NY) (2016) 0.75
Khat promotes human breast cancer MDA-MB-231 cell apoptosis via mitochondria and MAPK-associated pathways. Oncol Lett (2017) 0.75
Identification of three proteins involved in fertilization and parthenogenetic development of a brown alga, Scytosiphon lomentaria. Planta (2014) 0.75
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature (2001) 5.07
Mitochondrial control of nuclear apoptosis. J Exp Med (1996) 5.01
Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol (2000) 4.89
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med (1995) 4.88
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science (1998) 4.84
Mitochondrial control of apoptosis. Immunol Today (1997) 4.74
Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry (1996) 3.45
Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol (2001) 3.05
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J (2000) 2.65
The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J Exp Med (2000) 2.62
The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins. J Exp Med (1998) 2.51
Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med (1996) 2.39
NADH oxidase activity of mitochondrial apoptosis-inducing factor. J Biol Chem (2001) 2.22
Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death. Cell Death Differ (1999) 1.84
Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett (2000) 1.82
Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. J Immunol (1996) 1.64
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor. FASEB J (2001) 1.64
Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells. Cell Death Differ (2000) 1.64
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases. J Exp Med (2000) 1.59
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Lett (1996) 1.58
The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene (1997) 1.53
Mitochondria and programmed cell death: back to the future. FEBS Lett (1996) 1.52
Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes. Immunol Lett (1998) 1.51
Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition. FEBS Lett (1998) 1.49
Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins. Oncogene (1998) 1.47
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis. Oncogene (2000) 1.45
Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid. J Biol Chem (1998) 1.41
Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore. Exp Cell Res (1999) 1.33
Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis. Oncogene (2001) 1.32
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. J Infect Dis (2001) 1.30
Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. FEBS Lett (1997) 1.30
Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo. Am J Pathol (2001) 1.29
Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore. Oncogene (1999) 1.26
GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. FASEB J (2000) 1.24
Mitochondrial membrane permeabilization during the apoptotic process. Ann N Y Acad Sci (1999) 1.24
Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. Cancer Res (1996) 1.24
PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection. Exp Cell Res (1998) 1.23
Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release. Cell Death Differ (2005) 1.20
Caspases disrupt mitochondrial membrane barrier function. FEBS Lett (1998) 1.19
Mitochondrial permeability transition triggers lymphocyte apoptosis. J Immunol (1996) 1.19
BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation. Cell Death Differ (2011) 1.18
Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition. Cell Death Differ (2000) 1.15
Mitochondrial permeability transition in apoptosis and necrosis. Cell Biol Toxicol (1998) 1.11
Potassium leakage during the apoptotic degradation phase. J Immunol (1998) 1.09
The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition. Oncogene (1998) 1.09
Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis. J Immunol (1997) 1.08
HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism. FASEB J (2000) 1.08
Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function. Eur J Immunol (1997) 1.07
Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells. Cancer Res (1998) 1.06
AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation. Cell Death Dis (2012) 0.97
Palmitate induces apoptosis via a direct effect on mitochondria. Apoptosis (1999) 0.95
CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells. Oncogene (2006) 0.94
Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult. Blood (2000) 0.92
Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis. J Immunol (1998) 0.90
Simplification of complex peptide mixtures for proteomic analysis: reversible biotinylation of cysteinyl peptides. Electrophoresis (2000) 0.88
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus. Cancer Res (1999) 0.87
Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress. Apoptosis (2006) 0.87
Functional assessment of p53 in chronic lymphocytic leukemia. Blood Cancer J (2011) 0.85
Pre-processed caspase-9 contained in mitochondria participates in apoptosis. Cell Death Differ (2002) 0.85
Caspase-independent type III PCD: a new means to modulate cell death in chronic lymphocytic leukemia. Leukemia (2008) 0.81
Involvement of apoptosis-inducing factor during dolichyl monophosphate-induced apoptosis in U937 cells. FEBS Lett (2000) 0.77
GD3 ganglioside as an intracellular mediator of apoptosis. Eur Cytokine Netw (2000) 0.75
Cytofluorometric quantitation of nuclear apoptosis induced in a cell-free system. Methods Enzymol (2000) 0.75