Prevention of relapse following cognitive therapy vs medications in moderate to severe depression.

PubWeight™: 3.46‹?› | Rank: Top 1%

🔗 View Article (PMID 15809409)

Published in Arch Gen Psychiatry on April 01, 2005

Authors

Steven D Hollon1, Robert J DeRubeis, Richard C Shelton, Jay D Amsterdam, Ronald M Salomon, John P O'Reardon, Margaret L Lovett, Paula R Young, Kirsten L Haman, Brent B Freeman, Robert Gallop

Author Affiliations

1: Department of Psychology, Vanderbilt University, 306 Wilson Hall Nashville, TN 37203, USA. steven.d.hollon@vanderbilt.edu

Articles citing this

(truncated to the top 100)

Chronic and treatment resistant depression: diagnosis and stepwise therapy. Dtsch Arztebl Int (2014) 3.14

Depression and cardiovascular disease: healing the broken-hearted. JAMA (2006) 2.44

Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms. Nat Rev Neurosci (2008) 2.35

Effect of cognitive therapy with antidepressant medications vs antidepressants alone on the rate of recovery in major depressive disorder: a randomized clinical trial. JAMA Psychiatry (2014) 2.33

Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy's effects. J Consult Clin Psychol (2007) 2.22

Alzheimer disease: are we intervening too late? Pro. J Neural Transm (Vienna) (2011) 2.15

Major depressive disorder: new clinical, neurobiological, and treatment perspectives. Lancet (2011) 2.10

Treatment-resistant depressed patients show a good response to Mindfulness-based Cognitive Therapy. Behav Res Ther (2006) 2.03

Usual and unusual care: existing practice control groups in randomized controlled trials of behavioral interventions. Psychosom Med (2011) 1.93

Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the prevention of relapse and recurrence in major depression. J Consult Clin Psychol (2008) 1.87

Preventing depressive relapse and recurrence in higher-risk cognitive therapy responders: a randomized trial of continuation phase cognitive therapy, fluoxetine, or matched pill placebo. JAMA Psychiatry (2013) 1.77

A randomized controlled trial of cognitive-behavioral treatment for posttraumatic stress disorder in severe mental illness. J Consult Clin Psychol (2008) 1.72

Prediction of response to medication and cognitive therapy in the treatment of moderate to severe depression. J Consult Clin Psychol (2009) 1.67

Psychological treatments: A call for mental-health science. Nature (2014) 1.66

Stuck in a rut: rethinking depression and its treatment. Trends Neurosci (2010) 1.60

Personality change during depression treatment: a placebo-controlled trial. Arch Gen Psychiatry (2009) 1.56

The process of change in cognitive therapy for depression: predictors of early inter-session symptom gains. Behav Res Ther (2010) 1.53

Remission and recovery in the Treatment for Adolescents with Depression Study (TADS): acute and long-term outcomes. J Am Acad Child Adolesc Psychiatry (2009) 1.51

A review of empirically supported psychological therapies for mood disorders in adults. Depress Anxiety (2010) 1.50

Antidepressant medications v. cognitive therapy in people with depression with or without personality disorder. Br J Psychiatry (2008) 1.44

Using attentional bias modification as a cognitive vaccine against depression. Biol Psychiatry (2012) 1.44

Screening, assessment, and care of anxiety and depressive symptoms in adults with cancer: an American Society of Clinical Oncology guideline adaptation. J Clin Oncol (2014) 1.40

Relationship of personality disorders to the course of major depressive disorder in a nationally representative sample. Am J Psychiatry (2011) 1.37

Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP Trial. Arch Gen Psychiatry (2009) 1.35

Current Status and Future Prospects of Clinical Psychology: Toward a Scientifically Principled Approach to Mental and Behavioral Health Care. Psychol Sci Public Interest (2008) 1.34

Cost-effectiveness of collaborative care including PST and an antidepressant treatment algorithm for the treatment of major depressive disorder in primary care; a randomised clinical trial. BMC Health Serv Res (2007) 1.31

Cognitive behavioral therapy for mood disorders: efficacy, moderators and mediators. Psychiatr Clin North Am (2010) 1.29

Therapist competence in cognitive therapy for depression: predicting subsequent symptom change. J Consult Clin Psychol (2010) 1.29

Study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment in the prevention of depressive relapse/recurrence: the PREVENT trial. Trials (2010) 1.29

Antidepressant medications reduce subcortical-cortical resting-state functional connectivity in healthy volunteers. Neuroimage (2011) 1.26

Prevention of Relapse and Recurrence in Adults with Major Depressive Disorder: Systematic Review and Meta-Analyses of Controlled Trials. Int J Neuropsychopharmacol (2015) 1.22

The Personalized Advantage Index: translating research on prediction into individualized treatment recommendations. A demonstration. PLoS One (2014) 1.22

Does cognitive behaviour therapy have an enduring effect that is superior to keeping patients on continuation pharmacotherapy? A meta-analysis. BMJ Open (2013) 1.19

Remitted major depression is characterized by reward network hyperactivation during reward anticipation and hypoactivation during reward outcomes. J Affect Disord (2011) 1.18

Imagery about suicide in depression--"Flash-forwards"? J Behav Ther Exp Psychiatry (2007) 1.17

Predictors of nonresponse to cognitive behavioural therapy or venlafaxine using glucose metabolism in major depressive disorder. J Psychiatry Neurosci (2009) 1.16

Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy. AIDS Care (2009) 1.11

The chronometry of affective startle modulation in unipolar depression. J Abnorm Psychol (2008) 1.11

Exercise and pharmacotherapy in patients with major depression: one-year follow-up of the SMILE study. Psychosom Med (2010) 1.09

Personality disorders predict relapse after remission from an episode of major depressive disorder: a 6-year prospective study. J Clin Psychiatry (2010) 1.05

Changes in depressive symptoms in first time mothers in home visitation. Child Abuse Negl (2009) 1.00

CBT for the treatment of depression in Parkinson's disease: a promising nonpharmacological approach. Expert Rev Neurother (2008) 0.99

Developing a measure of interpretation bias for depressed mood: An ambiguous scenarios test. Pers Individ Dif (2011) 0.97

Comparative effectiveness of medication versus cognitive-behavioral therapy in a randomized controlled trial of low-income young minority women with depression. J Consult Clin Psychol (2012) 0.95

Change in psychosocial functioning and depressive symptoms during acute-phase cognitive therapy for depression. Psychol Med (2011) 0.95

Behavioral control blunts reactions to contemporaneous and future adverse events: medial prefrontal cortex plasticity and a corticostriatal network. Neurobiol Stress (2015) 0.94

Moderators of continuation phase cognitive therapy's effects on relapse, recurrence, remission, and recovery from depression. Behav Res Ther (2010) 0.94

Achievement and maintenance of sustained response during the Treatment for Adolescents With Depression Study continuation and maintenance therapy. Arch Gen Psychiatry (2008) 0.93

Psychopharmacologic management of opioid-dependent women during pregnancy. Am J Addict (2009) 0.92

Deep brain stimulation for treatment-resistant depression. Am J Psychiatry (2010) 0.92

Gains in employment status following antidepressant medication or cognitive therapy for depression. Br J Psychiatry (2014) 0.91

Cognitive-behavioral therapy vs. light therapy for preventing winter depression recurrence: study protocol for a randomized controlled trial. Trials (2013) 0.91

Evidence map of prevention and treatment interventions for depression in young people. Depress Res Treat (2012) 0.90

Effectiveness and cost-effectiveness of a minimal psychological intervention to reduce non-severe depression in chronically ill elderly patients: the design of a randomised controlled trial [ISRCTN92331982]. BMC Public Health (2006) 0.90

Effectiveness of counseling for anxiety and depression in mothers of children ages 0-30 months by community workers in Karachi, Pakistan: a quasi experimental study. BMC Psychiatry (2010) 0.87

Increasing Access to Cognitive-Behavioural Therapy (CBT) for the Treatment of Mental Illness in Canada: A Research Framework and Call for Action. Healthc Policy (2010) 0.87

An evaluation of the effect of an educational intervention for Australian social workers on competence in delivering brief cognitive behavioural strategies: a randomised controlled trial. BMC Health Serv Res (2010) 0.86

Continuation-phase cognitive therapy's effects on remission and recovery from depression. J Consult Clin Psychol (2009) 0.86

Problem-solving intervention for caregivers of children with mental health problems. Arch Psychiatr Nurs (2013) 0.86

A psychoeducational intervention (SWEEP) for depressed women with diabetes. Ann Behav Med (2012) 0.85

Disrupting the rhythm of depression: design and protocol of a randomized controlled trial on preventing relapse using brief cognitive therapy with or without antidepressants. BMC Psychiatry (2011) 0.85

Mental imagery in bipolar affective disorder versus unipolar depression: investigating cognitions at times of 'positive' mood. J Affect Disord (2014) 0.84

Differential change in specific depressive symptoms during antidepressant medication or cognitive therapy. Behav Res Ther (2013) 0.83

Safety and effectiveness of continuation antidepressant versus mood stabilizer monotherapy for relapse-prevention of bipolar II depression: A randomized, double-blind, parallel-group, prospective study. J Affect Disord (2015) 0.83

A two-factor model of relapse/recurrence vulnerability in unipolar depression. J Abnorm Psychol (2015) 0.82

Pretreatment anxiety predicts patterns of change in cognitive behavioral therapy and medications for depression. J Consult Clin Psychol (2013) 0.82

Augmenting antidepressant medication with modular CBT for geriatric generalized anxiety disorder: a pilot study. Int J Geriatr Psychiatry (2010) 0.82

Work-focused cognitive-behavioural therapy and individual job support to increase work participation in common mental disorders: a randomised controlled multicentre trial. Occup Environ Med (2015) 0.81

Acceptance and commitment therapy and behavioral activation for the treatment of depression: description and comparison. Behav Anal (2006) 0.81

Perspectives on Cognitive Therapy Training within Community Mental Health Settings: Implications for Clinician Satisfaction and Skill Development. Depress Res Treat (2012) 0.80

A systematic review of the combined use of electroconvulsive therapy and psychotherapy for depression. J ECT (2011) 0.80

Misconceptions of depression in african americans. Front Psychiatry (2014) 0.80

Effectiveness, relapse prevention and mechanisms of change of cognitive therapy vs. interpersonal therapy for depression: Study protocol for a randomised controlled trial. Trials (2011) 0.79

Efficacy of an adjunctive brief psychodynamic psychotherapy to usual inpatient treatment of depression: rationale and design of a randomized controlled trial. BMC Psychiatry (2012) 0.79

In cognitive therapy for depression, early focus on maladaptive beliefs may be especially efficacious for patients with personality disorders. J Consult Clin Psychol (2016) 0.79

Cognitive Therapy to Prevent Depressive Relapse in Adults. Curr Opin Psychol (2015) 0.79

Depression in adults: drug and physical treatments. BMJ Clin Evid (2007) 0.78

Are antidepressants effective in the acute and long-term treatment of depression? Sic et Non. Innov Clin Neurosci (2012) 0.77

Group psychotherapies for depression in persons with HIV: A systematic review. Indian J Psychiatry (2013) 0.77

A written self-help intervention for depressed adults comparing behavioural activation combined with physical activity promotion with a self-help intervention based upon behavioural activation alone: study protocol for a parallel group pilot randomised controlled trial (BAcPAc). Trials (2014) 0.77

Evidentiary Pluralism as a Strategy for Research and Evidence-Based Practice in Rehabilitation Psychology. Rehabil Psychol (2008) 0.77

From Mice to Men: Can Ketamine Enhance Resilience to Stress? Biol Psychiatry (2016) 0.76

Comparative effectiveness of cognitive and dynamic therapies for major depressive disorder in a community mental health setting: study protocol for a randomized non-inferiority trial. BMC Psychol (2014) 0.76

Use of treatment algorithms for depression. Prim Care Companion J Clin Psychiatry (2006) 0.76

Relabeling the medications we call antidepressants. Scientifica (Cairo) (2012) 0.76

Sexual orientation and treatment-seeking for depression in a multilingual worldwide sample. J Affect Disord (2016) 0.75

Therapist use of Socratic questioning predicts session-to-session symptom change in cognitive therapy for depression. Behav Res Ther (2015) 0.75

Cognitive Therapy Skills Predict Cognitive Reactivity to Sad Mood Following Cognitive Therapy for Depression. Cognit Ther Res (2013) 0.75

Autonomy, stress, and treatment of depression. BMJ (2008) 0.75

Depression in adults: psychological treatments and care pathways. BMJ Clin Evid (2007) 0.75

Tackling partial response to depression treatment. Prim Care Companion J Clin Psychiatry (2009) 0.75

Explanatory flexibility and explanatory style in treatment-seeking clients with Axis I psychopathology. Cognit Ther Res (2015) 0.75

Gynecologic care for breast cancer survivors: assisting in the transition to wellness. Am J Obstet Gynecol (2011) 0.75

One-Year Follow-Up of the Effectiveness of Cognitive Behavioral Group Therapy for Patients' Depression: A Randomized, Single-Blinded, Controlled Study. ScientificWorldJournal (2015) 0.75

Acceptance-based Behavior Therapy for Depression With Psychosis: Results From a Pilot Feasibility Randomized Controlled Trial. J Psychiatr Pract (2015) 0.75

Computer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy. J ECT (2016) 0.75

Advances in the Management of Treatment-Resistant Depression. Focus (Am Psychiatr Publ) (2010) 0.75

ETHICAL CONSIDERATIONS FOR COGNITIVE-BEHAVIORAL THERAPISTS IN PSYCHOTHERAPY RESEARCH TRIALS. Cogn Behav Pract (2009) 0.75

Preventive Cognitive Therapy versus Treatment as Usual in preventing recurrence of depression: protocol of a multi-centered randomized controlled trial. BMC Psychiatry (2015) 0.75

Cognitive-reminiscence therapy and usual care for depression in young adults: study protocol for a randomized controlled trial. Trials (2013) 0.75

Articles by these authors

Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA (2010) 13.88

Cognitive therapy vs medications in the treatment of moderate to severe depression. Arch Gen Psychiatry (2005) 5.72

Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. J Consult Clin Psychol (2006) 5.48

L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials. Am J Psychiatry (2012) 3.73

Combining medications to enhance depression outcomes (CO-MED): acute and long-term outcomes of a single-blind randomized study. Am J Psychiatry (2011) 3.34

Short-term dynamic psychotherapy versus pharmacotherapy for major depressive disorder: a randomized, placebo-controlled trial. J Clin Psychiatry (2011) 2.88

Efficacy and safety of baclofen for alcohol dependence: a randomized, double-blind, placebo-controlled trial. Alcohol Clin Exp Res (2010) 2.70

MDDScore: confirmation of a blood test to aid in the diagnosis of major depressive disorder. J Clin Psychiatry (2015) 2.66

Underuse of lung protective ventilation: analysis of potential factors to explain physician behavior. Crit Care Med (2006) 2.64

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nat Rev Drug Discov (2012) 2.44

Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies. Am J Obstet Gynecol (2012) 2.16

Augmentation of antidepressants with atypical antipsychotic medications for treatment-resistant major depressive disorder: a meta-analysis. J Clin Psychiatry (2007) 2.10

The dependability of alliance assessments: the alliance-outcome correlation is larger than you might think. J Consult Clin Psychol (2011) 2.00

The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry (2013) 1.97

A simple clinical predictive index for objective estimates of mortality in acute lung injury. Crit Care Med (2009) 1.91

Transcranial magnetic stimulation in the treatment of major depressive disorder: a comprehensive summary of safety experience from acute exposure, extended exposure, and during reintroduction treatment. J Clin Psychiatry (2008) 1.89

Attachment-based family therapy for adolescents with suicidal ideation: a randomized controlled trial. J Am Acad Child Adolesc Psychiatry (2010) 1.82

Preventing depression among early adolescents in the primary care setting: a randomized controlled study of the Penn Resiliency Program. J Abnorm Child Psychol (2006) 1.79

Signal transduction abnormalities in melancholic depression. Int J Neuropsychopharmacol (2004) 1.73

Are antidepressant drugs that combine serotonergic and noradrenergic mechanisms of action more effective than the selective serotonin reuptake inhibitors in treating major depressive disorder? A meta-analysis of studies of newer agents. Biol Psychiatry (2007) 1.68

Transdermal selegiline in major depression: a double-blind, placebo-controlled, parallel-group study in outpatients. Am J Psychiatry (2002) 1.68

Prediction of response to medication and cognitive therapy in the treatment of moderate to severe depression. J Consult Clin Psychol (2009) 1.67

Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia. J Abnorm Psychol (2012) 1.63

ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. Am J Respir Crit Care Med (2011) 1.62

Depressive symptoms are associated with unrealistic negative predictions of future life events. Behav Res Ther (2005) 1.59

School-based prevention of depressive symptoms: A randomized controlled study of the effectiveness and specificity of the Penn Resiliency Program. J Consult Clin Psychol (2007) 1.57

Heterogeneous phenotypes of acute respiratory distress syndrome after major trauma. Ann Am Thorac Soc (2014) 1.57

Assessment of sleep in women with night eating syndrome. Sleep (2006) 1.56

Personality change during depression treatment: a placebo-controlled trial. Arch Gen Psychiatry (2009) 1.56

The Night Eating Questionnaire (NEQ): psychometric properties of a measure of severity of the Night Eating Syndrome. Eat Behav (2007) 1.56

Health-related quality of life in patients with pulmonary arterial hypertension. Respir Res (2005) 1.55

The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) Study: Outcomes from the 2-year and combined maintenance phases. J Clin Psychiatry (2007) 1.54

Randomized, double-blind, placebo-controlled crossover trials of venlafaxine for hot flashes after breast cancer. Oncologist (2007) 1.54

The process of change in cognitive therapy for depression: predictors of early inter-session symptom gains. Behav Res Ther (2010) 1.53

Cognitive changes, critical sessions, and sudden gains in cognitive-behavioral therapy for depression. J Consult Clin Psychol (2005) 1.53

Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase. Proc Natl Acad Sci U S A (2005) 1.53

Therapists as fixed versus random effects-some statistical and conceptual issues: a comment on Siemer and Joormann (2003). Psychol Methods (2003) 1.52

Comorbid psychiatric disorders in depressed outpatients: demographic and clinical features. J Affect Disord (2005) 1.49

Efficacy, safety, and tolerability of sertraline in patients with late-life depression and comorbid medical illness. J Am Geriatr Soc (2004) 1.49

Treatment with venlafaxine extended release after SSRI nonresponse or intolerance: a randomized comparison of standard- and higher-dosing strategies. J Clin Psychopharmacol (2006) 1.47

Patients' competence in and performance of cognitive therapy skills: relation to the reduction of relapse risk following treatment for depression. J Consult Clin Psychol (2007) 1.46

Agomelatine for the treatment of major depressive disorder. Expert Opin Pharmacother (2011) 1.45

Antidepressant medications v. cognitive therapy in people with depression with or without personality disorder. Br J Psychiatry (2008) 1.44

The current crisis of confidence in antidepressants. J Clin Psychiatry (2011) 1.44

Functional biomarkers of depression: diagnosis, treatment, and pathophysiology. Neuropsychopharmacology (2011) 1.44

Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): a pragmatic 6-month trial of lithium versus quetiapine for bipolar disorder. J Clin Psychiatry (2016) 1.43

A randomized, double-blind, active-control study of sertraline versus venlafaxine XR in major depressive disorder. J Clin Psychiatry (2006) 1.42

Proposed diagnostic criteria for night eating syndrome. Int J Eat Disord (2010) 1.41

Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT Study. J Clin Psychiatry (2007) 1.40

The impact of development of acute lung injury on hospital mortality in critically ill trauma patients. Crit Care Med (2008) 1.38

Relation of depression diagnoses to 2-year outcomes in cocaine-dependent patients in a randomized continuing care study. Psychol Addict Behav (2002) 1.34

Therapist competence in cognitive therapy for depression: predicting subsequent symptom change. J Consult Clin Psychol (2010) 1.29

Review of pharmacological treatment in mood disorders and future directions for drug development. Neuropsychopharmacology (2011) 1.28

Treatment preferences affect the therapeutic alliance: implications for randomized controlled trials. J Consult Clin Psychol (2007) 1.28

Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine. J Psychiatr Res (2008) 1.26

Uncommon but serious complications associated with electroconvulsive therapy: recognition and management for the clinician. Curr Psychiatry Rep (2008) 1.22

Early- and late-onset startle modulation in unipolar depression. Psychophysiology (2004) 1.20

Prevalence of the night eating syndrome in a psychiatric population. Am J Psychiatry (2006) 1.20

Circadian rhythm profiles in women with night eating syndrome. J Biol Rhythms (2009) 1.19

The process of change in cognitive therapy for depression when combined with antidepressant medication: Predictors of early intersession symptom gains. J Consult Clin Psychol (2012) 1.18

The psychometric properties of the MASC in a pediatric psychiatric sample. J Anxiety Disord (2006) 1.18

Sustained amygdala response to both novel and newly familiar faces characterizes inhibited temperament. Soc Cogn Affect Neurosci (2010) 1.17

The alliance in motivational enhancement therapy and counseling as usual for substance use problems. J Consult Clin Psychol (2009) 1.16

Prevention of depression in at-risk adolescents: longer-term effects. JAMA Psychiatry (2013) 1.15

Causal Mediation Analyses for Randomized Trials. Health Serv Outcomes Res Methodol (2008) 1.15

Unique and common mechanisms of change across cognitive and dynamic psychotherapies. J Consult Clin Psychol (2009) 1.14

Extreme nonresponse in cognitive therapy: can behavioral activation succeed where cognitive therapy fails? J Consult Clin Psychol (2007) 1.13

Neuroendocrine profiles associated with energy intake, sleep, and stress in the night eating syndrome. J Clin Endocrinol Metab (2005) 1.12

Retention in psychosocial treatment of cocaine dependence: predictors and impact on outcome. Am J Addict (2002) 1.12

The relation of patients' treatment preferences to outcome in a randomized clinical trial. Behav Ther (2007) 1.10

Night eating syndrome among nonobese persons. Int J Eat Disord (2004) 1.10

A descriptive study of non-obese persons with night eating syndrome and a weight-matched comparison group. Eat Behav (2008) 1.09

Evaluation of disease-specific health-related quality of life in patients with pulmonary arterial hypertension. Respir Med (2008) 1.09

HIV risk reduction in the National Institute on Drug Abuse Cocaine Collaborative Treatment Study. J Acquir Immune Defic Syndr (2003) 1.09

Two aspects of the therapeutic alliance: differential relations with depressive symptom change. J Consult Clin Psychol (2011) 1.08

Progressive resistance to a selective serotonin reuptake inhibitor but not to cognitive therapy in the treatment of major depression. J Consult Clin Psychol (2007) 1.08

The night eating syndrome: a progress report. Appetite (2005) 1.08

A randomized, double-blind, crossover trial of modafinil on mood. J Clin Psychopharmacol (2007) 1.08

Durability of clinical benefit with transcranial magnetic stimulation (TMS) in the treatment of pharmacoresistant major depression: assessment of relapse during a 6-month, multisite, open-label study. Brain Stimul (2010) 1.07