Published in Adv Drug Deliv Rev on April 25, 2005
A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition. Nat Cell Biol (2009) 3.12
Physiology and function of the tight junction. Cold Spring Harb Perspect Biol (2009) 3.06
Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14. Nat Med (2010) 2.58
The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. Science (2010) 2.02
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. J Virol (2008) 1.62
Picornaviruses. Curr Top Microbiol Immunol (2010) 1.53
Ectoplasmic specialization: a friend or a foe of spermatogenesis? Bioessays (2007) 1.52
Effect of cell polarization on hepatitis C virus entry. J Virol (2007) 1.41
IFITM1 is a tight junction protein that inhibits hepatitis C virus entry. Hepatology (2012) 1.36
Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses. Cancer Res (2009) 1.24
Modifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from Kupffer cells. Mol Ther (2010) 1.23
Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X. PLoS Pathog (2010) 1.19
Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest (2008) 1.18
Multimerization of adenovirus serotype 3 fiber knob domains is required for efficient binding of virus to desmoglein 2 and subsequent opening of epithelial junctions. J Virol (2011) 1.17
Tight junctions in the testis: new perspectives. Philos Trans R Soc Lond B Biol Sci (2010) 1.16
Sertoli-germ cell junctions in the testis: a review of recent data. Philos Trans R Soc Lond B Biol Sci (2010) 1.12
A seamless trespass: germ cell migration across the seminiferous epithelium during spermatogenesis. J Cell Biol (2007) 1.10
Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface. Exp Cell Res (2007) 1.07
Epithelial ICAM-1 and ICAM-2 regulate the egression of human T cells across the bronchial epithelium. FASEB J (2008) 1.06
Inadequately treated wastewater as a source of human enteric viruses in the environment. Int J Environ Res Public Health (2010) 1.05
Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis. Mucosal Immunol (2008) 1.05
Tight junctions: a barrier to the initiation and progression of breast cancer? J Biomed Biotechnol (2009) 1.01
Novel fiber-dependent entry mechanism for adenovirus serotype 5 in lacrimal acini. J Virol (2006) 1.00
Coagulation factors IX and X enhance binding and infection of adenovirus types 5 and 31 in human epithelial cells. J Virol (2009) 0.95
Claudins: Gatekeepers of lung epithelial function. Semin Cell Dev Biol (2015) 0.94
Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells. J Virol (2006) 0.94
Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene. PLoS One (2011) 0.94
Neurotrophin gene therapy for sustained neural preservation after deafness. PLoS One (2012) 0.93
Adenoviral vectors for improved gene delivery to the inner ear. Hear Res (2008) 0.92
The effect of deafness duration on neurotrophin gene therapy for spiral ganglion neuron protection. Hear Res (2011) 0.91
Loss of Coxsackie and adenovirus receptor downregulates alpha-catenin expression. Br J Cancer (2009) 0.90
Mechanisms of viral entry: sneaking in the front door. Protoplasma (2010) 0.88
Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses. J Control Release (2012) 0.88
Desmosomes in the testis: Moving into an unchartered territory. Spermatogenesis (2011) 0.88
Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications. Viruses (2015) 0.87
Connections matter--how viruses use cell–cell adhesion components. J Cell Sci (2015) 0.87
Paradigms lost-an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesis. Ann Transl Med (2015) 0.86
Accessibility of the coxsackievirus and adenovirus receptor and its importance in adenovirus gene transduction efficiency. J Gen Virol (2011) 0.85
Tight Junctions Go Viral! Viruses (2015) 0.84
Coxsackievirus and adenovirus receptor expression in human endometrial adenocarcinoma: possible clinical implications. World J Surg Oncol (2008) 0.84
CAR regulates epithelial cell junction stability through control of E-cadherin trafficking. Sci Rep (2013) 0.82
Hepatic tight junctions: from viral entry to cancer metastasis. World J Gastroenterol (2010) 0.81
Human enterovirus species B in ileocecal Crohn's disease. Clin Transl Gastroenterol (2013) 0.80
Histone deacetylase inhibitors restore cell surface expression of the coxsackie adenovirus receptor and enhance CMV promoter activity in castration-resistant prostate cancer cells. Prostate Cancer (2012) 0.80
Expression of coxsackie and adenovirus receptor distinguishes transitional cancer states in therapy-induced cellular senescence. Cell Death Dis (2010) 0.80
Therapeutic efficacy by targeting correction of Notch1-induced aberrants in uveal tumors. PLoS One (2012) 0.79
HDAC inhibitor valproic acid upregulates CAR in vitro and in vivo. Genet Vaccines Ther (2007) 0.79
Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair. Gastroenterology (2016) 0.79
Pregnancy loss following coxsackievirus b3 infection in mice during early gestation due to high expression of coxsackievirus-adenovirus receptor (CAR) in uterus and embryo. Exp Anim (2014) 0.79
The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP). PLoS One (2013) 0.78
Molecular insights into γδ T cell costimulation by an anti-JAML antibody. Structure (2011) 0.78
Induction of cytopathic effect and cytokines in coxsackievirus B3-infected murine astrocytes. Virol J (2013) 0.78
The Intracellular Domain of the Coxsackievirus and Adenovirus Receptor Differentially Influences Adenovirus Entry. J Virol (2015) 0.77
Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells. Am J Obstet Gynecol (2008) 0.77
Use of nucleofection to efficiently transfect primary rabbit lacrimal gland acinar cells. Cytotechnology (2011) 0.76
TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers. Sci Rep (2016) 0.76
Emergence of a Large-Plaque Variant in Mice Infected with Coxsackievirus B3. MBio (2016) 0.76
The Coxsackievirus and Adenovirus Receptor: Glycosylation and the Extracellular D2 Domain Are Not Required for Coxsackievirus B3 Infection. J Virol (2016) 0.75
Two types of functionally distinct fiber containing structural protein complexes are produced during infection of adenovirus serotype 5. PLoS One (2015) 0.75
What is CAR doing in the middle of the adult neurogenic road? Neurogenesis (Austin) (2017) 0.75
Gene transfer into cardiac myocytes. Methods Mol Biol (2015) 0.75
Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions. Cell (2006) 4.68
Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. Cell Host Microbe (2007) 3.34
Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product. J Virol (2002) 2.31
Adenovirus receptors. J Virol (2005) 1.55
Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2. EMBO J (2007) 1.44
Beta1 integrin mediates internalization of mammalian reovirus. J Virol (2006) 1.43
Chimpanzee adenovirus CV-68 adapted as a gene delivery vector interacts with the coxsackievirus and adenovirus receptor. J Gen Virol (2002) 1.38
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction. J Biol Chem (2004) 1.37
Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family. EMBO J (2002) 1.37
Structure-based identification of a major neutralizing site in an adenovirus hexon. J Virol (2006) 1.17
Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves. Circ Res (2006) 1.16
Interaction with decay-accelerating factor facilitates coxsackievirus B infection of polarized epithelial cells. J Virol (2002) 1.14
Interaction with coxsackievirus and adenovirus receptor, but not with decay-accelerating factor (DAF), induces A-particle formation in a DAF-binding coxsackievirus B3 isolate. J Virol (2005) 1.13
VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. J Virol (2002) 1.10
Enterovirus 71 binding to PSGL-1 on leukocytes: VP1-145 acts as a molecular switch to control receptor interaction. PLoS Pathog (2013) 1.07
Dynamin- and lipid raft-dependent entry of decay-accelerating factor (DAF)-binding and non-DAF-binding coxsackieviruses into nonpolarized cells. J Virol (2009) 1.05
Single amino acid changes in the virus capsid permit coxsackievirus B3 to bind decay-accelerating factor. J Virol (2011) 1.03
Effect of preexisting immunity on an adenovirus vaccine vector: in vitro neutralization assays fail to predict inhibition by antiviral antibody in vivo. J Virol (2009) 0.99
Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells. Mol Biol Cell (2011) 0.93
Efficient transduction of human monocyte-derived dendritic cells by chimpanzee-derived adenoviral vector. Hum Gene Ther (2003) 0.93
Receptors identified for hand, foot and mouth virus. Nat Med (2009) 0.93
A novel gain-of-function mutation of the integrin alpha2 VWFA domain. Eur J Biochem (2002) 0.92
Tissue-specific deletion of the coxsackievirus and adenovirus receptor protects mice from virus-induced pancreatitis and myocarditis. Cell Host Microbe (2009) 0.90
Echovirus 1 entry into polarized Caco-2 cells depends on dynamin, cholesterol, and cellular factors associated with macropinocytosis. J Virol (2013) 0.89
Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu. Clin Cancer Res (2002) 0.88
Echovirus 7 entry into polarized intestinal epithelial cells requires clathrin and Rab7. MBio (2012) 0.86
High-efficiency gene transfer to primary T lymphocytes by recombinant adenovirus vectors. J Immunol Methods (2002) 0.85
Structure and chromosomal localization of the murine coxsackievirus and adenovirus receptor gene. DNA Cell Biol (2003) 0.84
A zebrafish coxsackievirus and adenovirus receptor homologue interacts with coxsackie B virus and adenovirus. J Virol (2002) 0.82
Echovirus 7 entry into polarized caco-2 intestinal epithelial cells involves core components of the autophagy machinery. J Virol (2013) 0.80