Published in Pharmacol Res on June 01, 2005
M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage. Cell (2004) 2.46
Antioxidant supplementation enhances the exercise-induced increase in mitochondrial uncoupling protein 3 and endothelial nitric oxide synthase mRNA content in human skeletal muscle. Free Radic Biol Med (2007) 1.70
Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation. Free Radic Biol Med (2002) 1.46
Oxidants and antioxidants in disease: oxidative stress in farm animals. Vet J (2006) 1.41
Antioxidant supplementation does not alter endurance training adaptation. Med Sci Sports Exerc (2010) 1.30
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci U S A (2002) 1.29
Authors' perspective: What is the optimum intake of vitamin C in humans? Crit Rev Food Sci Nutr (2012) 1.20
Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles. Blood (2002) 1.18
Neutrophil-derived heparin-binding protein (HBP/CAP37) deposited on endothelium enhances monocyte arrest under flow conditions. J Immunol (2005) 1.17
Does vitamin C deficiency increase lifestyle-associated vascular disease progression? Evidence based on experimental and clinical studies. Antioxid Redox Signal (2013) 1.07
Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation. Free Radic Biol Med (2005) 1.05
Mild streptozotocin diabetes in the Göttingen minipig. A novel model of moderate insulin deficiency and diabetes. Am J Physiol Endocrinol Metab (2002) 1.04
Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes. Eur J Neurosci (2007) 0.97
Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs. Am J Clin Nutr (2009) 0.95
High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs. Br J Nutr (2010) 0.94
Regulation of vitamin C homeostasis during deficiency. Nutrients (2013) 0.93
Increased manganese concentration in the liver after oral intake. Acad Radiol (2004) 0.92
Experimental infection with Escherichia coli O149:F4ac in weaned piglets. Vet Microbiol (2006) 0.92
Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training. Am J Physiol Endocrinol Metab (2011) 0.92
Vitamin C supplementation decreases oxidative DNA damage in mononuclear blood cells of smokers. Eur J Nutr (2004) 0.92
The young Göttingen minipig as a model of childhood and adolescent obesity: influence of diet and gender. Obesity (Silver Spring) (2013) 0.89
Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs. PLoS One (2012) 0.89
Whey protein reduces early life weight gain in mice fed a high-fat diet. PLoS One (2013) 0.89
Gender-associated differences in metabolic syndrome-related parameters in Göttingen minipigs. Comp Med (2007) 0.88
High-fat high-energy feeding impairs fasting glucose and increases fasting insulin levels in the Göttingen minipig: results from a pilot study. Ann N Y Acad Sci (2002) 0.88
Role of vitamin C and E supplementation on IL-6 in response to training. J Appl Physiol (1985) (2011) 0.87
Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells. Toxicol Lett (2011) 0.87
Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV. Eur J Pharmacol (2005) 0.86
Influence of castration-induced testosterone and estradiol deficiency on obesity and glucose metabolism in male Göttingen minipigs. Steroids (2010) 0.86
Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men. Am J Clin Nutr (2004) 0.85
Plasma calcitonin gene-related peptide is increased prior to obesity, and sensory nerve desensitization by capsaicin improves oral glucose tolerance in obese Zucker rats. Eur J Endocrinol (2005) 0.85
Poor vitamin C status is associated with increased carotid intima-media thickness, decreased microvascular function, and delayed myocardial repolarization in young patients with type 1 diabetes. Am J Clin Nutr (2009) 0.85
Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture. Anal Biochem (2009) 0.85
Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone. J Neurochem (2004) 0.84
Increased systemic oxidatively generated DNA and RNA damage in schizophrenia. Psychiatry Res (2013) 0.84
Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs. Br J Nutr (2013) 0.83
Ethics and animal welfare related to in vivo pharmacology and toxicology in laboratory animals. Basic Clin Pharmacol Toxicol (2005) 0.82
Vitamin C pharmacokinetics of plain and slow release formulations in smokers. Clin Nutr (2004) 0.81
Role of marginal vitamin C deficiency in atherogenesis: in vivo models and clinical studies. Basic Clin Pharmacol Toxicol (2009) 0.81
Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo. Nutr Res (2013) 0.81
Valine pyrrolidide preserves intact glucose-dependent insulinotropic peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell mass. Exp Diabesity Res (2003) 0.81
Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats. Exp Hematol (2012) 0.80
Electroencephalographic changes after pediatric cardiac surgery with cardiopulmonary bypass: is slow wave activity unfavorable? Pediatr Res (2005) 0.80
Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs. Basic Clin Pharmacol Toxicol (2012) 0.80
Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components. Scand J Clin Lab Invest (2011) 0.80
Differential toxicological response to positively and negatively charged nanoparticles in the rat brain. Nanotoxicology (2014) 0.79
Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis. J Neuropathol Exp Neurol (2002) 0.79
Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial. Surg Laparosc Endosc Percutan Tech (2012) 0.79
Does vitamin C deficiency result in impaired brain development in infants? Redox Rep (2009) 0.79
Antioxidant supplementation for lung disease in cystic fibrosis. Cochrane Database Syst Rev (2014) 0.78
Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure. Diab Vasc Dis Res (2011) 0.78
Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation. Basic Clin Pharmacol Toxicol (2014) 0.78
Effect of local anaesthesia on neuronal c-fos expression in the spinal dorsal horn and hypothalamic paraventricular nucleus after surgery in rats. Basic Clin Pharmacol Toxicol (2005) 0.78
Utility of melatonin to treat surgical stress after major vascular surgery--a safety study. J Pineal Res (2008) 0.77
Circadian variation in the response to experimental endotoxemia and modulatory effects of exogenous melatonin. Chronobiol Int (2013) 0.77
Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in guinea pigs. Basic Clin Pharmacol Toxicol (2011) 0.77
Pharmacokinetics of amoxicillin after oral administration in recently weaned piglets with experimentally induced Escherichia coli subtype O149:F4 diarrhea. Am J Vet Res (2004) 0.77
Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs. Res Vet Sci (2003) 0.76
Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function. Biomarkers (2012) 0.76
Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs. Pflugers Arch (2014) 0.76
Translational aspects of rectal evoked potentials: a comparative study in rats and humans. Am J Physiol Gastrointest Liver Physiol (2013) 0.76
Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs. Eur J Nutr (2014) 0.76
Sensory nerve inactivation by resiniferatoxin improves insulin sensitivity in male obese Zucker rats. Am J Physiol Endocrinol Metab (2005) 0.76
Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics. Basic Clin Pharmacol Toxicol (2013) 0.75
High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice. Eur J Nutr (2014) 0.75
Identifying the functional part of heparin-binding protein (HBP) as a monocyte stimulator and the novel role of monocytes as HBP producers. Innate Immun (2010) 0.75
Pharmacokinetics of amoxicillin administered in drinking water to recently weaned 3- to 4-week-old pigs with diarrhea experimentally induced by Escherichia coli O149:F4. Am J Vet Res (2006) 0.75
Effect of High Inspiratory Oxygen Fraction on Endothelial Function in Healthy Volunteers: A Randomized Controlled Crossover Pilot Study. Anesth Analg (2017) 0.75
Positive charge, negative effect: the impact of cationic nanoparticles in the brain. Nanomedicine (Lond) (2014) 0.75
Antioxidant supplementation for lung disease in cystic fibrosis. Cochrane Database Syst Rev (2019) 0.75
Erratum to: Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs. Eur J Nutr (2015) 0.75