Published in Zhonghua Er Ke Za Zhi on February 01, 2005
Sir2 blocks extreme life-span extension. Cell (2005) 4.25
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci Transl Med (2011) 3.84
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc Natl Acad Sci U S A (2008) 3.30
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest (2012) 3.14
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci Transl Med (2012) 2.58
Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells. Immunity (2006) 2.56
RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings. Cell Res (2012) 2.41
Proteome analysis of laser microdissected glomeruli from formalin-fixed paraffin-embedded kidneys of autopsies of diabetic patients: nephronectin is associated with the development of diabetic glomerulosclerosis. Nephrol Dial Transplant (2011) 2.12
CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets. Blood (2009) 1.94
Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia. Blood (2007) 1.83
Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 derived miniRNA as a novel plasma-based biomarker for diagnosing prostate cancer. Eur J Cancer (2013) 1.73
Fasting and cancer treatment in humans: A case series report. Aging (Albany NY) (2009) 1.71
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res (2010) 1.69
Existence of no hepatocarcinogenic effect levels of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline with or without coadministration with ethanol. Toxicol Pathol (2006) 1.66
Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia. J Neurosci (2002) 1.66
Long noncoding RNA MALAT-1 is a new potential therapeutic target for castration resistant prostate cancer. J Urol (2013) 1.64
Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation. PLoS Genet (2010) 1.59
Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. Exp Gerontol (2013) 1.57
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors. Nat Med (2012) 1.52
Self-assembled multivalent DNA nanostructures for noninvasive intracellular delivery of immunostimulatory CpG oligonucleotides. ACS Nano (2011) 1.52
Factors influencing the removal of fluoride from aqueous solution by calcined Mg-Al-CO3 layered double hydroxides. J Hazard Mater (2005) 1.49
TGF-beta utilizes SMAD3 to inhibit CD16-mediated IFN-gamma production and antibody-dependent cellular cytotoxicity in human NK cells. J Immunol (2008) 1.43
Compared study of Asian reduction malarplasty: wedge-section osteotomy versus conventional procedures. J Craniofac Surg (2009) 1.41
Platelets and fibrinogen facilitate each other in protecting tumor cells from natural killer cytotoxicity. Cancer Sci (2009) 1.33
The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor. Urol Oncol (2012) 1.33
NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human. J Clin Invest (2011) 1.30
Effects of pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, on the urine and urothelium of the rat. Toxicol Sci (2009) 1.29
Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system. J Cell Biol (2008) 1.26
DNA damage repair in bladder urothelium after the Chernobyl accident in Ukraine. J Urol (2002) 1.25
Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polzeta-dependent mechanism. J Cell Biol (2009) 1.23
Micelle density regulated by a reversible switch of protein secondary structure. J Am Chem Soc (2006) 1.21
MicroRNA-340 suppresses osteosarcoma tumor growth and metastasis by directly targeting ROCK1. Biochem Biophys Res Commun (2013) 1.20
Formation of and coalescence from the inclusion complex of a biodegradable block copolymer and alpha-cyclodextrin. 2: A novel way to regulate the biodegradation behavior of biodegradable block copolymers. Biomacromolecules (2002) 1.19
A cocrystal strategy to tune the luminescent properties of stilbene-type organic solid-state materials. Angew Chem Int Ed Engl (2011) 1.18
Fasting enhances the response of glioma to chemo- and radiotherapy. PLoS One (2012) 1.18
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination. Proc Natl Acad Sci U S A (2009) 1.18
Involvement of ubiquitination and sumoylation in bladder lesions induced by persistent long-term low dose ionizing radiation in humans. J Urol (2006) 1.18
MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer. Cancer Lett (2012) 1.16
MicroRNAs activate natural killer cells through Toll-like receptor signaling. Blood (2013) 1.15
Profiling non-lysyl tRNAs in HIV-1. RNA (2009) 1.14
Controllable preparation of Nano-MgO and investigation of its bactericidal properties. J Inorg Biochem (2005) 1.13
Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer. J Mol Med (Berl) (2012) 1.12
Ascl1 lineage cells contribute to ischemia-induced neurogenesis and oligodendrogenesis. J Cereb Blood Flow Metab (2010) 1.10
Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model. J Med Chem (2009) 1.09
Humidity-triggered self-healing films with excellent oxygen barrier performance. Chem Commun (Camb) (2014) 1.08
Exogenous nitric oxide protect cucumber roots against oxidative stress induced by salt stress. Plant Physiol Biochem (2007) 1.07
SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice. Aging Cell (2013) 1.06
ZnO nanotube-based dye-sensitized solar cell and its application in self-powered devices. Nanotechnology (2010) 1.06
Characterization of five nearly full-length genomes of early HIV type 1 strains in Ruili city: implications for the genesis of CRF07_BC and CRF08_BC circulating in China. AIDS Res Hum Retroviruses (2005) 1.03
Biased G-to-A hypermutation in HIV-1 proviral DNA from a long-term non-progressor. AIDS (2004) 1.01
TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia. Blood (2009) 1.01
Morroniside and loganin extracted from Cornus officinalis have protective effects on rat mesangial cell proliferation exposed to advanced glycation end products by preventing oxidative stress. Can J Physiol Pharmacol (2006) 1.00
Preparation of Fe3O4@SiO2@layered double hydroxide core-shell microspheres for magnetic separation of proteins. J Am Chem Soc (2012) 0.99
Nonsense mutation in the CRYBB2 gene causing autosomal dominant progressive polymorphic congenital coronary cataracts. Mol Vis (2008) 0.99
Reversible age impairments in neurite outgrowth by manipulations of astrocytic GFAP. Neurobiol Aging (2005) 0.98
Significant and systematic expression differentiation in long-lived yeast strains. PLoS One (2007) 0.98
[Distribution of recombinant human immunodeficiency virus type-1 CRF01_AE strains in China and its sequence variations in the env V3-C3 region]. Zhonghua Yu Fang Yi Xue Za Zhi (2004) 0.98
Sonic hedgehog signaling pathway mediates cerebrolysin-improved neurological function after stroke. Stroke (2013) 0.96
Transcriptional control of human T-BET expression: the role of Sp1. Eur J Immunol (2007) 0.96
IκBζ augments IL-12- and IL-18-mediated IFN-γ production in human NK cells. Blood (2011) 0.96
Macrosialin increases during normal brain aging are attenuated by caloric restriction. Neurosci Lett (2005) 0.95
Effect of graphene oxide on undifferentiated and retinoic acid-differentiated SH-SY5Y cells line. Nanoscale (2012) 0.95
Foveal versus full-field visual stabilization strategies for translational and rotational head movements. J Neurosci (2003) 0.95
Study on UV-shielding mechanism of layered double hydroxide materials. Phys Chem Chem Phys (2013) 0.94
Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics. J Biol Chem (2006) 0.94
Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells. Blood (2008) 0.94
Cytokeratin 8/18 overexpression and complex formation as an indicator of GST-P positive foci transformation into hepatocellular carcinomas. Toxicol Appl Pharmacol (2009) 0.94
Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer. Int J Oncol (2011) 0.94
Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevity. Aging Cell (2014) 0.94
Promoter polymorphism of interleukin-18 in angiographically proven coronary artery disease. Angiology (2008) 0.93
Increased susceptibility to spontaneous lung cancer in mice lacking LIM-domain only 7. Cancer Sci (2009) 0.93
Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis. Biochemistry (2002) 0.93
Sildenafil enhances neurogenesis and oligodendrogenesis in ischemic brain of middle-aged mouse. PLoS One (2012) 0.93
Diagnosis and classification of congenital craniofacial cleft deformities. J Craniofac Surg (2006) 0.92
Urinary bladder carcinogenesis induced by chronic exposure to persistent low-dose ionizing radiation after Chernobyl accident. Carcinogenesis (2009) 0.92
Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics. J Med Chem (2005) 0.92
Estradiol (E2) enhances neurite outgrowth by repressing glial fibrillary acidic protein expression and reorganizing laminin. Endocrinology (2002) 0.92
Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: synthesis and structure-activity relationships of a peptide scaffold. Bioorg Med Chem (2006) 0.92
Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic. J Med Chem (2006) 0.91
Uptake of chloride ion from aqueous solution by calcined layered double hydroxides: equilibrium and kinetic studies. Water Res (2006) 0.91
Urinary bladder lesions induced by persistent chronic low-dose ionizing radiation. Cancer Sci (2003) 0.91
Cytokeratin 8/18 as a new marker of mouse liver preneoplastic lesions. Toxicol Appl Pharmacol (2009) 0.91
Liver tumorigenicity of trimethylarsine oxide in male Fischer 344 rats--association with oxidative DNA damage and enhanced cell proliferation. Carcinogenesis (2003) 0.91
Enhancement of the nitrogen fixation efficiency of genetically-engineered Rhizobium with high catalase activity. J Biosci Bioeng (2010) 0.91
CD94 defines phenotypically and functionally distinct mouse NK cell subsets. J Immunol (2009) 0.90
Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry (2007) 0.89
Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis. Toxicol Sci (2010) 0.89
Understanding arsenic carcinogenicity by the use of animal models. Toxicol Appl Pharmacol (2004) 0.89
Mutational analysis of ATP7B in north Chinese patients with Wilson disease. J Hum Genet (2012) 0.89
Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model. Aging Cell (2013) 0.88
Myristoylated alanine-rich C-kinase substrate as a prognostic biomarker in human primary lung squamous cell carcinoma. Cancer Biomark (2013) 0.88
Carcinogenicity of dimethylarsinic acid in p53 heterozygous knockout and wild-type C57BL/6J mice. Carcinogenesis (2003) 0.88
Repair of canine mandibular bone defects with bone marrow stromal cells and coral. Tissue Eng Part A (2010) 0.87
Clinicopathological significance of combined analysis of cytokeratin19 expression and preoperative serum CYFRA21-1 levels in human lung squamous cell carcinoma. Osaka City Med J (2013) 0.87
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine. Jpn J Cancer Res (2002) 0.87
Elevation of 8-hydroxydeoxyguanosine and cell proliferation via generation of oxidative stress by organic arsenicals contributes to their carcinogenicity in the rat liver and bladder. Toxicol Appl Pharmacol (2007) 0.87
Treatment of high fluoride concentration water by MgAl-CO3 layered double hydroxides: kinetic and equilibrium studies. Water Res (2007) 0.87
Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice. Cancer Sci (2007) 0.86
Progesterone influence on neurite outgrowth involves microglia. Endocrinology (2008) 0.86