Published in J Comp Neurol on May 23, 2005
Social isolation delays the positive effects of running on adult neurogenesis. Nat Neurosci (2006) 2.52
Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A (2007) 2.31
Cardiorespiratory fitness and preserved medial temporal lobe volume in Alzheimer disease. Alzheimer Dis Assoc Disord (2009) 1.99
Running induces widespread structural alterations in the hippocampus and entorhinal cortex. Hippocampus (2007) 1.91
A neuroimaging investigation of the association between aerobic fitness, hippocampal volume, and memory performance in preadolescent children. Brain Res (2010) 1.90
Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice. Hippocampus (2009) 1.84
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Bridging animal and human models of exercise-induced brain plasticity. Trends Cogn Sci (2013) 1.79
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway. Cell Metab (2013) 1.76
Determination of key aspects of precursor cell proliferation, cell cycle length and kinetics in the adult mouse subgranular zone. Neuroscience (2007) 1.75
Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin. Proc Natl Acad Sci U S A (2014) 1.69
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A review of the effects of physical activity and exercise on cognitive and brain functions in older adults. J Aging Res (2013) 1.58
The neuropathology of sport. Acta Neuropathol (2013) 1.49
Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease. Lancet Neurol (2013) 1.48
Experience induces structural and biochemical changes in the adult primate brain. Proc Natl Acad Sci U S A (2005) 1.47
Antidepressant effects of exercise: evidence for an adult-neurogenesis hypothesis? J Psychiatry Neurosci (2006) 1.41
Structural plasticity and hippocampal function. Annu Rev Psychol (2010) 1.40
The effects of exercise and stress on the survival and maturation of adult-generated granule cells. Hippocampus (2009) 1.39
Exercise and time-dependent benefits to learning and memory. Neuroscience (2010) 1.39
Cardiovascular fitness is associated with cognition in young adulthood. Proc Natl Acad Sci U S A (2009) 1.30
Heterogeneous integration of adult-generated granule cells into the epileptic brain. J Neurosci (2011) 1.26
All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis. Curr Top Behav Neurosci (2013) 1.25
Biological mechanisms of physical activity in preventing cognitive decline. Cell Mol Neurobiol (2009) 1.20
Impact of energy intake and expenditure on neuronal plasticity. Neuromolecular Med (2008) 1.17
Sexual experience promotes adult neurogenesis in the hippocampus despite an initial elevation in stress hormones. PLoS One (2010) 1.12
A behavioral analysis of the impact of voluntary physical activity on hippocampus-dependent contextual conditioning. Hippocampus (2009) 1.12
Increased cortical thickness in sports experts: a comparison of diving players with the controls. PLoS One (2011) 1.08
Neuronal and cognitive plasticity: a neurocognitive framework for ameliorating cognitive aging. Front Aging Neurosci (2010) 1.07
Central mechanisms of HPA axis regulation by voluntary exercise. Neuromolecular Med (2008) 1.06
Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus. Mol Cell Neurosci (2008) 1.05
Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice. Neurosci Lett (2009) 1.05
Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus. Hippocampus (2010) 1.03
Pharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents. Curr Med Chem (2009) 1.02
Neuroprotective effects of physical activity on the brain: a closer look at trophic factor signaling. Front Cell Neurosci (2014) 1.01
Progesterone treatment normalizes the levels of cell proliferation and cell death in the dentate gyrus of the hippocampus after traumatic brain injury. Exp Neurol (2011) 1.01
Prenatal alcohol exposure reduces the proportion of newly produced neurons and glia in the dentate gyrus of the hippocampus in female rats. Horm Behav (2010) 0.98
Hippocampal neurogenesis, depressive disorders, and antidepressant therapy. Neural Plast (2007) 0.98
New neurons generated from running are broadly recruited into neuronal activation associated with three different hippocampus-involved tasks. Hippocampus (2012) 0.97
The effects of exercise on adolescent hippocampal neurogenesis in a rat model of binge alcohol exposure during the brain growth spurt. Brain Res (2009) 0.96
Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice. Brain Res (2010) 0.95
Exercise neuroprotection in a rat model of binge alcohol consumption. Alcohol Clin Exp Res (2009) 0.95
Moderate exercise delays the motor performance decline in a transgenic model of ALS. Brain Res (2009) 0.95
Physical exercise improves functional recovery through mitigation of autophagy, attenuation of apoptosis and enhancement of neurogenesis after MCAO in rats. BMC Neurosci (2013) 0.95
Morphometry of hilar ectopic granule cells in the rat. J Comp Neurol (2011) 0.92
In vivo imaging of adult human hippocampal neurogenesis: progress, pitfalls and promise. Mol Psychiatry (2013) 0.91
Morphometric analysis in neurodegenerative disorders. Curr Protoc Toxicol (2010) 0.88
Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? Biomed Res Int (2014) 0.87
The effect of treadmill running on passive avoidance learning in animal model of Alzheimer disease. Int J Prev Med (2013) 0.87
The effect of tai chi on cognition in elders with cognitive impairment. Medsurg Nurs (2011) 0.87
Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease. Neurobiol Dis (2013) 0.87
Learning an operant conditioning task differentially induces gliogenesis in the medial prefrontal cortex and neurogenesis in the hippocampus. PLoS One (2011) 0.85
Housing in environmental complexity following wheel running augments survival of newly generated hippocampal neurons in a rat model of binge alcohol exposure during the third trimester equivalent. Alcohol Clin Exp Res (2012) 0.85
Exercise reduces diet-induced cognitive decline and increases hippocampal brain-derived neurotrophic factor in CA3 neurons. Neurobiol Learn Mem (2014) 0.84
Analyzing dendritic growth in a population of immature neurons in the adult dentate gyrus using laminar quantification of disjointed dendrites. Front Neurosci (2011) 0.84
Metabolic disturbances in diseases with neurological involvement. Aging Dis (2013) 0.84
Stage-dependent alterations of progenitor cell proliferation and neurogenesis in an animal model of Wernicke-Korsakoff syndrome. Brain Res (2011) 0.84
Effects of exercise intensity on spatial memory performance and hippocampal synaptic plasticity in transient brain ischemic rats. PLoS One (2013) 0.83
The benefits of endurance exercise and Tai Chi Chuan for the task-switching aspect of executive function in older adults: an ERP study. Front Aging Neurosci (2014) 0.83
Captivity reduces hippocampal volume but not survival of new cells in a food-storing bird. Dev Neurobiol (2009) 0.83
MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat. J Neurotrauma (2014) 0.83
The Effects of Exercise on Dopamine Neurotransmission in Parkinson's Disease: Targeting Neuroplasticity to Modulate Basal Ganglia Circuitry. Brain Plast (2015) 0.82
Alcohol dependence-induced regulation of the proliferation and survival of adult brain progenitors is associated with altered BDNF-TrkB signaling. Brain Struct Funct (2015) 0.82
Physical exercise habits correlate with gray matter volume of the hippocampus in healthy adult humans. Sci Rep (2013) 0.82
The 5-HT3 receptor is essential for exercise-induced hippocampal neurogenesis and antidepressant effects. Mol Psychiatry (2014) 0.81
Using causal models to distinguish between neurogenesis-dependent and -independent effects on behaviour. J R Soc Interface (2011) 0.81
Increased adult hippocampal neurogenesis is not necessary for wheel running to abolish conditioned place preference for cocaine in mice. Eur J Neurosci (2014) 0.80
Synaptic remodeling in the dentate gyrus, CA3, CA1, subiculum, and entorhinal cortex of mice: effects of deprived rearing and voluntary running. Neural Plast (2010) 0.80
Physical exercise promotes recovery of neurological function after ischemic stroke in rats. Int J Mol Sci (2014) 0.80
Physical exercise enhances cognitive flexibility as well as astrocytic and synaptic markers in the medial prefrontal cortex. PLoS One (2015) 0.80
Effects of exercise and environmental complexity on deficits in trace and contextual fear conditioning produced by neonatal alcohol exposure in rats. Dev Psychobiol (2012) 0.80
Exercise and early-onset Alzheimer's disease: theoretical considerations. Dement Geriatr Cogn Dis Extra (2012) 0.79
Long-term consequences of developmental alcohol exposure on brain structure and function: therapeutic benefits of physical activity. Brain Sci (2012) 0.79
Role of exercise on the brain. J Exerc Rehabil (2016) 0.79
Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment. Front Hum Neurosci (2016) 0.78
Motor Skills and Exercise Capacity Are Associated with Objective Measures of Cognitive Functions and Academic Performance in Preadolescent Children. PLoS One (2016) 0.78
Differential cortical neurotrophin and cytogenetic adaptation after voluntary exercise in normal and amnestic rats. Neuroscience (2013) 0.78
The adaptive significance of adult neurogenesis: an integrative approach. Front Neuroanat (2013) 0.78
Impact of treadmill running and sex on hippocampal neurogenesis in the mouse model of amyotrophic lateral sclerosis. PLoS One (2012) 0.78
Improved Cardiorespiratory Fitness Is Associated with Increased Cortical Thickness in Mild Cognitive Impairment. J Int Neuropsychol Soc (2015) 0.78
Alcohol and pregnancy: Effects on maternal care, HPA axis function, and hippocampal neurogenesis in adult females. Psychoneuroendocrinology (2015) 0.78
Can physical exercise in old age improve memory and hippocampal function? Brain (2016) 0.78
Neurogenesis and maturation in neonatal brain injury. Clin Perinatol (2013) 0.78
Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders. Neuroimage (2015) 0.78
The Effect of Synchronized Forced Running with Chronic Stress on Short, Mid and Long- term Memory in Rats. Asian J Sports Med (2012) 0.78
Wheel running reduces ethanol seeking by increasing neuronal activation and reducing oligodendroglial/neuroinflammatory factors in the medial prefrontal cortex. Brain Behav Immun (2016) 0.77
SMART: physical activity and cerebral metabolism in older people: study protocol for a randomised controlled trial. Trials (2015) 0.77
Primary prevention of Alzheimer's disease: is it an attainable goal? J Korean Med Sci (2014) 0.77
Blockage of the upregulation of voltage-gated sodium channel nav1.3 improves outcomes after experimental traumatic brain injury. J Neurotrauma (2013) 0.77
Voluntary exercise partially reverses neonatal alcohol-induced deficits in mPFC layer II/III dendritic morphology of male adolescent rats. Synapse (2015) 0.77
Mediators of Physical Activity on Neurocognitive Function: A Review at Multiple Levels of Analysis. Front Hum Neurosci (2016) 0.76
Identifying and characterizing the effects of nutrition on hippocampal memory. Adv Nutr (2014) 0.76
Flow cytometric determination of 5-bromo-2'-deoxyuridine pharmacokinetics in blood serum after intraperitoneal administration to rats and mice. Histochem Cell Biol (2014) 0.76
Unified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapy. J Mol Psychiatry (2016) 0.76
The effect of a skilled reaching task on hippocampal plasticity after intracerebral hemorrhage in adult rats. J Phys Ther Sci (2015) 0.75
Prenatal Alcohol Exposure Affects Progenitor Cell Numbers in Olfactory Bulbs and Dentate Gyrus of Vervet Monkeys. Brain Sci (2016) 0.75
Hippocampal morphology in a rat model of depression: the effects of physical activity. Open Neuroimag J (2015) 0.75
Parameters for abolishing conditioned place preference for cocaine from running and environmental enrichment in male C57BL/6J mice. Behav Brain Res (2016) 0.75
Neurogenesis and the effect of antidepressants. Drug Target Insights (2006) 0.75
Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats. Front Neurosci (2016) 0.75
Functional neurogenesis in the adult hippocampus. Nature (2002) 11.17
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc Natl Acad Sci U S A (2003) 2.44
Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways. Hippocampus (2006) 2.43
Active dendrites, potassium channels and synaptic plasticity. Philos Trans R Soc Lond B Biol Sci (2003) 1.90
Antidepressant effects of exercise: evidence for an adult-neurogenesis hypothesis? J Psychiatry Neurosci (2006) 1.41
Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus. Hippocampus (2010) 1.39
Hippocampal long-term depression mediates acute stress-induced spatial memory retrieval impairment. Proc Natl Acad Sci U S A (2007) 1.26
Contribution of NR2A and NR2B NMDA subunits to bidirectional synaptic plasticity in the hippocampus in vivo. Hippocampus (2006) 1.25
Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models. Brain Res Rev (2010) 1.24
Hippocampal cell proliferation is reduced following prenatal ethanol exposure but can be rescued with voluntary exercise. Hippocampus (2006) 1.13
Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus. Hippocampus (2010) 1.03
Effects of exercise on NMDA receptor subunit contributions to bidirectional synaptic plasticity in the mouse dentate gyrus. Hippocampus (2007) 1.02
NMDA receptor hypofunction in the dentate gyrus and impaired context discrimination in adult Fmr1 knockout mice. Hippocampus (2010) 0.99
Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease. Neurobiol Dis (2010) 0.98
Anxiety- and depression-like behaviors are accompanied by an increase in oxidative stress in a rat model of fetal alcohol spectrum disorders: Protective effects of voluntary physical exercise. Neuropharmacology (2011) 0.98
Stress differentially regulates the effects of voluntary exercise on cell proliferation in the dentate gyrus of mice. Hippocampus (2009) 0.97
Hippocampal neurogenesis levels predict WATERMAZE search strategies in the aging brain. PLoS One (2013) 0.97
NGF is essential for hippocampal plasticity and learning. J Neurosci (2009) 0.96
Voluntary exercise induces adult hippocampal neurogenesis and BDNF expression in a rodent model of fetal alcohol spectrum disorders. Eur J Neurosci (2011) 0.96
The role of norepinephrine in differential response to stress in an animal model of posttraumatic stress disorder. Biol Psychiatry (2011) 0.96
Tyrosine phosphorylation of the GluR2 subunit is required for long-term depression of synaptic efficacy in young animals in vivo. Hippocampus (2007) 0.95
The role of oxidative stress in fetal alcohol spectrum disorders. Brain Res Rev (2011) 0.95
Isolectin-IB 4 as a vascular stain for the study of adult neurogenesis. J Neurosci Methods (2005) 0.93
Running reduces stress and enhances cell genesis in aged mice. Neurobiol Aging (2010) 0.93
Nestin-expressing cells and their relationship to mitotically active cells in the subventricular zones of the adult rat. Eur J Neurosci (2005) 0.90
Long-term exercise is needed to enhance synaptic plasticity in the hippocampus. Learn Mem (2013) 0.89
Neurogenesis in Huntington's disease: can studying adult neurogenesis lead to the development of new therapeutic strategies? Brain Res (2011) 0.89
Altered adult hippocampal neuronal maturation in a rat model of fetal alcohol syndrome. Brain Res (2011) 0.89
Omega-3 supplementation can restore glutathione levels and prevent oxidative damage caused by prenatal ethanol exposure. J Nutr Biochem (2012) 0.88
Prolonged cannabinoid treatment results in spatial working memory deficits and impaired long-term potentiation in the CA1 region of the hippocampus in vivo. Eur J Neurosci (2004) 0.88
Glutathione restores the mechanism of synaptic plasticity in aged mice to that of the adult. PLoS One (2011) 0.86
Omega-3 fatty acids can reverse the long-term deficits in hippocampal synaptic plasticity caused by prenatal ethanol exposure. Neurosci Lett (2013) 0.86
Temporally specific proliferation events are induced in the hippocampus following acute focal injury. J Neurosci Res (2006) 0.85
Differential response of hippocampal subregions to stress and learning. PLoS One (2012) 0.84
Sustained running in rats administered corticosterone prevents the development of depressive behaviors and enhances hippocampal neurogenesis and synaptic plasticity without increasing neurotrophic factor levels. Cell Transplant (2014) 0.84
Prenatal ethanol exposure enhances NMDAR-dependent long-term potentiation in the adolescent female dentate gyrus. Hippocampus (2010) 0.83
Reduced synaptic plasticity in the lateral perforant path input to the dentate gyrus of aged C57BL/6 mice. J Neurophysiol (2003) 0.83
5-HT(2A) receptor mediated neuronal activation within the paraventricular nucleus of the hypothalamus is desensitized following prolonged glucocorticoid treatment. Eur J Pharmacol (2008) 0.80
Cognition, learning behaviour and hippocampal synaptic plasticity are not disrupted in mice over-expressing the cholesterol transporter ABCG1. Lipids Health Dis (2009) 0.80
Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption. PLoS One (2012) 0.79
Impairments in hippocampal synaptic plasticity following prenatal ethanol exposure are dependent on glutathione levels. Hippocampus (2013) 0.76
Characterization of the neurogenesis quiescent zone in the rodent brain: effects of age and exercise. Eur J Neurosci (2010) 0.76
Prenatal ethanol (EtOH) exposure alters the sensitivity of the adult dentate gyrus to acute EtOH exposure. Alcohol Clin Exp Res (2013) 0.75
Long-term depression in vivo: effects of sex, stress, diet, and prenatal ethanol exposure. Hippocampus (2008) 0.75
Exercising some control over the hippocampus. Hippocampus (2009) 0.75