Published in Kidney Int on May 01, 2005
Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells. Nephrol Dial Transplant (2009) 1.10
Angiotensin II activates AMPK for execution of apoptosis through energy-dependent and -independent mechanisms. Am J Physiol Lung Cell Mol Physiol (2011) 0.85
Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor. PLoS One (2012) 0.76
N-Aryl Isoleucine Derivatives as Angiotensin II AT2 Receptor Ligands. ChemistryOpen (2014) 0.75
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J Mol Biol (1999) 15.63
Activation of the OxyR transcription factor by reversible disulfide bond formation. Science (1998) 7.16
Positive selection of a gene family during the emergence of humans and African apes. Nature (2001) 3.68
Structural basis of the redox switch in the OxyR transcription factor. Cell (2001) 3.32
Molecular basis of receptor/G-protein-coupling selectivity. Pharmacol Ther (1998) 2.00
Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues. Mol Pharmacol (1998) 1.94
Molecular cloning and expression of the rat beta 3-adrenergic receptor. Mol Pharmacol (1991) 1.84
Recent progress in angiotensin II type 2 receptor research in the cardiovascular system. Hypertension (1999) 1.60
Gene targeting--homing in on alpha 2-adrenoceptor-subtype function. Trends Pharmacol Sci (1997) 1.51
A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1. J Biol Chem (1997) 1.50
Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists. J Biol Chem (2002) 1.30
Angiotensin II type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase. Biochem J (1997) 1.22
Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111). Biochemistry (1998) 1.21
The angiotensin II type 2 receptor: an enigma with multiple variations. Am J Physiol Endocrinol Metab (2000) 1.18
Rodent and human beta 3-adrenergic receptor genes contain an intron within the protein-coding block. Mol Pharmacol (1992) 1.03
Angiotensin II type 2 receptor subtype mediates phospholipase A2-dependent signaling in rabbit proximal tubular epithelial cells. Hypertension (1996) 0.99
Genetic transfer of a nonpeptide antagonist binding site to a previously unresponsive angiotensin receptor. Proc Natl Acad Sci U S A (1995) 0.96
A new method to localize and test the significance of incongruence: detecting domain shuffling in the nuclear receptor superfamily. Syst Biol (2000) 0.95
Gbeta gamma -independent constitutive association of Galpha s with SHP-1 and angiotensin II receptor AT2 is essential in AT2-mediated ITIM-independent activation of SHP-1. Proc Natl Acad Sci U S A (2002) 0.89
Heterogeneity of angiotensin II AT2 receptors in the rat brain. Mol Pharmacol (1992) 0.87
Reversible inactivation of AT(2) angiotensin II receptor from cysteine-disulfide bond exchange. FEBS Lett (2000) 0.86
Rabbit renal epithelial angiotensin II receptors. Am J Physiol (1994) 0.85
Role of transmembrane helix IV in G-protein specificity of the angiotensin II type 1 receptor. J Biol Chem (1999) 0.81
Cloning and expression of angiotensin II type 2 (AT2) receptors from murine neuroblastoma N1E-115 cells: evidence for AT2 receptor heterogeneity. Brain Res Mol Brain Res (1997) 0.78
Heterogeneity of angiotensin type 2 (AT2) receptors. Adv Exp Med Biol (1996) 0.78
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol (2008) 23.93
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science (2011) 13.16
Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. Lancet (2008) 10.74
Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA (2011) 6.81
Evaluation of the bacterial diversity in the feces of cattle using 16S rDNA bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP). BMC Microbiol (2008) 6.28
Ecological impacts of invasive alien plants: a meta-analysis of their effects on species, communities and ecosystems. Ecol Lett (2011) 5.95
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol (2012) 5.82
Treatment of anemia with darbepoetin alfa in systolic heart failure. N Engl J Med (2013) 4.67
Survey of bacterial diversity in chronic wounds using pyrosequencing, DGGE, and full ribosome shotgun sequencing. BMC Microbiol (2008) 4.30
Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial. Lancet Oncol (2013) 4.20
Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group. J Clin Oncol (2003) 3.51
De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia. Nat Genet (2012) 3.49
Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem Biol (2010) 3.38
Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial. Lancet Oncol (2010) 3.30
Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell (2011) 3.00
Icotinib versus gefitinib in previously treated advanced non-small-cell lung cancer (ICOGEN): a randomised, double-blind phase 3 non-inferiority trial. Lancet Oncol (2013) 2.94
Rac function and regulation during Drosophila development. Nature (2002) 2.89
Polymicrobial nature of chronic diabetic foot ulcer biofilm infections determined using bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP). PLoS One (2008) 2.87
Bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP) for microbiome studies: bacterial diversity in the ileum of newly weaned Salmonella-infected pigs. Foodborne Pathog Dis (2008) 2.77
Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial. Lancet Oncol (2011) 2.75
Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. Cell Stem Cell (2012) 2.62
The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader. Cell (2003) 2.50
Computational analysis of bacterial RNA-Seq data. Nucleic Acids Res (2013) 2.50
Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China. Cancer Epidemiol Biomarkers Prev (2005) 2.45
Randomized phase III placebo-controlled trial of letrozole plus oral temsirolimus as first-line endocrine therapy in postmenopausal women with locally advanced or metastatic breast cancer. J Clin Oncol (2012) 2.44
Randomized, multicenter, open-label study of oxaliplatin plus fluorouracil/leucovorin versus doxorubicin as palliative chemotherapy in patients with advanced hepatocellular carcinoma from Asia. J Clin Oncol (2013) 2.44
Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer. Cancer Cell (2013) 2.34
The rationale and design of the AASK cohort study. J Am Soc Nephrol (2003) 2.34
Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer. J Clin Oncol (2010) 2.34
A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell (2006) 2.20
Rac GTPases control axon growth, guidance and branching. Nature (2002) 2.14
Crop diversity for yield increase. PLoS One (2009) 2.02
MicroRNA-1 regulates cardiomyocyte apoptosis by targeting Bcl-2. Int Heart J (2009) 2.01
Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia. Gastroenterology (2009) 1.89
Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. Invest Ophthalmol Vis Sci (2005) 1.88
The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. J Clin Invest (2013) 1.76
Expression of nerve growth factor and tyrosine kinase receptor A and correlation with perineural invasion in pancreatic cancer. J Gastroenterol Hepatol (2008) 1.67
Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. Antimicrob Agents Chemother (2010) 1.60
Development of polydimethylsiloxane substrates with tunable elastic modulus to study cell mechanobiology in muscle and nerve. PLoS One (2012) 1.54
Predictive value of simple clinical and laboratory variables for dengue hemorrhagic fever in adults. J Clin Virol (2008) 1.54
Impaired angiogenesis in aminopeptidase N-null mice. Proc Natl Acad Sci U S A (2007) 1.53
Lack of efficacy of prophylactic platelet transfusion for severe thrombocytopenia in adults with acute uncomplicated dengue infection. Clin Infect Dis (2009) 1.53
Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. J Clin Invest (2012) 1.52
Phase III, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer. J Clin Oncol (2012) 1.52
Rhizobacterial volatile emissions regulate auxin homeostasis and cell expansion in Arabidopsis. Planta (2007) 1.51
Oxidative signaling in renal epithelium: Critical role of cytosolic phospholipase A2 and p38(SAPK). Free Radic Biol Med (2006) 1.46
Gene delivery by lipoplexes and polyplexes. Eur J Pharm Sci (2010) 1.45
Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and titanium amplicon pyrosequencing and metagenomic approaches. BMC Microbiol (2009) 1.45
IL-10/TGF-beta-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis. J Am Soc Nephrol (2010) 1.44
Successful blood pressure control in the African American Study of Kidney Disease and Hypertension. Arch Intern Med (2002) 1.43
Longitudinal Survey of Microbiota in Hospitalized Preterm Very-Low-Birth-Weight Infants. J Pediatr Gastroenterol Nutr (2016) 1.42
Small RNA-mediated activation of sugar phosphatase mRNA regulates glucose homeostasis. Cell (2013) 1.39
Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia. Circulation (2008) 1.39
A comparison of bacterial composition in diabetic ulcers and contralateral intact skin. Open Microbiol J (2010) 1.39
Soil bacteria confer plant salt tolerance by tissue-specific regulation of the sodium transporter HKT1. Mol Plant Microbe Interact (2008) 1.39
[Results of randomized, multicenter, double-blind phase III trial of rh-endostatin (YH-16) in treatment of advanced non-small cell lung cancer patients]. Zhongguo Fei Ai Za Zhi (2005) 1.38
Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China. Cancer Prev Res (Phila) (2011) 1.37
Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats. Drug Metab Dispos (2009) 1.34
An in vivo polymicrobial biofilm wound infection model to study interspecies interactions. PLoS One (2011) 1.34
Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One (2012) 1.32
MiRNA expression analysis of cancer-associated fibroblasts and normal fibroblasts in breast cancer. Int J Biochem Cell Biol (2012) 1.32
Pseudorabies virus variant in Bartha-K61-vaccinated pigs, China, 2012. Emerg Infect Dis (2013) 1.31
MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. J Pathol (2014) 1.31
PubChem3D: a new resource for scientists. J Cheminform (2011) 1.31
Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame. Cell Res (2009) 1.29
Evaluation of the bacterial diversity of pressure ulcers using bTEFAP pyrosequencing. BMC Med Genomics (2010) 1.28
Effect of recombinant adenovirus-p53 combined with radiotherapy on long-term prognosis of advanced nasopharyngeal carcinoma. J Clin Oncol (2008) 1.28
Molecular ecology of pyrethroid knockdown resistance in Culex pipiens pallens mosquitoes. PLoS One (2010) 1.27
Phase II study of sunitinib as second-line treatment for advanced gastric cancer. Invest New Drugs (2010) 1.25
Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation. Blood (2010) 1.24
Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation. J Immunol (2009) 1.23
A strong correlation between fusogenicity and membrane insertion depth of the HIV fusion peptide. Proc Natl Acad Sci U S A (2009) 1.23
Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1. J Immunol (2012) 1.21
MyD88 regulation of Fusarium keratitis is dependent on TLR4 and IL-1R1 but not TLR2. J Immunol (2008) 1.19
Toll-like receptors at the ocular surface. Ocul Surf (2008) 1.18
Bioactive electrospun scaffolds delivering growth factors and genes for tissue engineering applications. Pharm Res (2010) 1.18
Genetic amplification of the vascular endothelial growth factor (VEGF) pathway genes, including VEGFA, in human osteosarcoma. Cancer (2011) 1.17
The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population. J Affect Disord (2008) 1.17
A soil bacterium regulates plant acquisition of iron via deficiency-inducible mechanisms. Plant J (2009) 1.17
Determinants of salt sensitivity in black and white normotensive and hypertensive women. Hypertension (2003) 1.17
Host defense at the ocular surface. Int Rev Immunol (2013) 1.16
Fabry-Perot diaphragm fiber-optic sensor. Appl Opt (2007) 1.15
Effects of length of abstinence on decision-making and craving in methamphetamine abusers. PLoS One (2013) 1.15
Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain. Neuropharmacology (2008) 1.14
Defective viral genomes arising in vivo provide critical danger signals for the triggering of lung antiviral immunity. PLoS Pathog (2013) 1.12
Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: a randomized, phase III trial. J Clin Oncol (2013) 1.12
C-Jun NH2 terminal kinase (JNK) is an essential mediator of Toll-like receptor 2-induced corneal inflammation. J Leukoc Biol (2008) 1.11
Xyloglucan endotransglycosylase/hydrolase genes in cotton and their role in fiber elongation. Planta (2010) 1.11
Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness). Infect Immun (2004) 1.10
Modulation of host cell responses and evasion strategies for porcine reproductive and respiratory syndrome virus. Virus Res (2010) 1.10
Comparison of culture and molecular identification of bacteria in chronic wounds. Int J Mol Sci (2012) 1.10
The impact of voluntary exercise on mental health in rodents: a neuroplasticity perspective. Behav Brain Res (2008) 1.09
Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease. Kidney Int (2013) 1.07
Rare Lipomatous Tumors with Osseous and/or Chondroid Differentiation in the Oral Cavity Report of Two Cases and Review of the Literature. Int J Dent (2009) 1.07
Natural herbal medicine Lianhuaqingwen capsule anti-influenza A (H1N1) trial: a randomized, double blind, positive controlled clinical trial. Chin Med J (Engl) (2011) 1.07
A phase II study of biweekly paclitaxel and cisplatin chemotherapy for recurrent or metastatic esophageal squamous cell carcinoma: ERCC1 expression predicts response to chemotherapy. Med Oncol (2012) 1.06
Transcriptional control of the arginine/lysine transporter, cat-1, by physiological stress. J Biol Chem (2003) 1.05
Mist1 regulates pancreatic acinar cell proliferation through p21 CIP1/WAF1. Gastroenterology (2008) 1.04
Relationship between hepatitis B virus DNA levels and liver histology in patients with chronic hepatitis B. World J Gastroenterol (2007) 1.04