Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 2362047)

Published in Br J Cancer on May 09, 2005

Authors

Y Ueno1, H Sakurai, M Matsuo, M K Choo, K Koizumi, I Saiki

Author Affiliations

1: Division of Pathogenic Biochemistry, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.

Articles cited by this

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med (2004) 71.08

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science (2004) 61.56

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science (2004) 11.58

EGFR and cancer prognosis. Eur J Cancer (2001) 7.52

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J Cell Biol (2004) 5.44

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J Biol Chem (1999) 5.16

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor. Proc Natl Acad Sci U S A (1985) 4.42

Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin Cancer Res (2000) 3.95

Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res (2000) 3.75

Tumour-necrosis factor from the rabbit. I. Mode of action, specificity and physicochemical properties. Br J Cancer (1978) 3.38

Epidermal growth factor receptor dependence in human tumors: more than just expression? Oncologist (2002) 2.62

Tumour-necrosis factor from the rabbit. II. Production by monocytes. Br J Cancer (1978) 2.48

EGFR signal transactivation in cancer cells. Biochem Soc Trans (2003) 2.42

Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist (2002) 2.05

ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res (2002) 1.67

Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J Biol Chem (2004) 1.47

Enhancement of experimental metastasis by tumor necrosis factor. J Exp Med (1993) 1.40

The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors. Semin Oncol (2003) 1.32

Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells. Cancer Res (2002) 1.28

Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma. Pathol Res Pract (2001) 1.23

Induced autocrine signaling through the epidermal growth factor receptor contributes to the response of mammary epithelial cells to tumor necrosis factor alpha. J Biol Chem (2004) 1.18

Epidermal growth factor receptor transactivation mediates tumor necrosis factor-induced hepatocyte replication. J Biol Chem (2004) 1.17

The role of TNF and its family members in inflammation and cancer: lessons from gene deletion. Curr Drug Targets Inflamm Allergy (2002) 1.16

Targeting the epidermal growth factor receptor in non-small cell lung cancer. Clin Cancer Res (2003) 1.15

ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, shows antimetastatic activity using a hepatocellular carcinoma model. Mol Cancer Ther (2003) 1.12

Redox-sensitive transactivation of epidermal growth factor receptor by tumor necrosis factor confers the NF-kappa B activation. J Biol Chem (2001) 1.07

Spontaneous regression of lung metastasis in the absence of tumor necrosis factor receptor p55. Int J Cancer (2004) 1.00

TNF-alpha promotes progression of peritoneal metastasis as demonstrated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line. Clin Exp Metastasis (2004) 0.97

Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis. J Exp Med (1993) 0.96

Gefitinib ('Iressa', ZD1839) and new epidermal growth factor receptor inhibitors. Br J Cancer (2004) 0.96

Stimulation of cultured colon 26 cells with TNF-alpha promotes lung metastasis through the extracellular signal-regulated kinase pathway. Cancer Lett (2005) 0.86

Social isolation stress augments angiogenesis induced by colon 26-L5 carcinoma cells in mice. Clin Exp Metastasis (2000) 0.82

Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839. Int J Oncol (2003) 0.79

Protection against liver injury by PGE1 or anti-TNF-alpha is associated with a reduction of TNF-R1 expression in hepatocytes. Scand J Gastroenterol (2003) 0.78

Intrahepatic metastasis by orthotopic implantation of a fragment of murine hepatoma and its related molecules. Tumour Biol (2001) 0.77

Articles by these authors

(truncated to the top 100)

Giant Rashba-type spin splitting in bulk BiTeI. Nat Mater (2011) 2.49

Increased MR signal intensity due to cervical myelopathy. Analysis of 29 surgical cases. J Neurosurg (1991) 2.22

Color Doppler evaluation of valvular regurgitation in normal subjects. Circulation (1988) 2.21

Smoking prevalence and attitudes toward smoking among Japanese physicians. JAMA (2001) 2.19

Studies of prevalence of Japanese cedar pollinosis among the residents in a densely cultivated area. Ann Allergy (1987) 1.92

Insertion of a 5' truncated L1 element into the 3' end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy. J Clin Invest (1993) 1.92

Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells. Br J Cancer (2007) 1.87

Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R)- and 20(S)-ginsenoside-Rg3, of red ginseng. Biol Pharm Bull (1995) 1.85

Factors associated with operative risk in mitral valve replacement. Am J Cardiol (1969) 1.85

Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways. J Immunol (2001) 1.85

CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis. Cancer Res (1999) 1.82

Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging. Radiology (1993) 1.81

Regulation of POU genes by castor and hunchback establishes layered compartments in the Drosophila CNS. Genes Dev (1998) 1.74

Glucagon: role in the hyperglycemia of diabetes mellitus. Science (1975) 1.72

Genetic pathways in the evolution of morphologically distinct colorectal neoplasms. Cancer Res (2001) 1.70

Visual results and complications of temporal incision phacoemulsification performed with the non-dominant left hand by junior ophthalmologists. Br J Ophthalmol (2002) 1.69

Tumor markers CEA, CA19-9 and CA125 in monitoring of response to systemic chemotherapy in patients with advanced gastric cancer. Jpn J Clin Oncol (1999) 1.67

Nocturnal fall of blood pressure and silent cerebrovascular damage in elderly hypertensive patients. Advanced silent cerebrovascular damage in extreme dippers. Hypertension (1996) 1.65

Characterization of a new antigenic type, Kuroki, of Rickettsia tsutsugamushi isolated from a patient in Japan. J Clin Microbiol (1990) 1.60

Critical contribution of IFN-gamma and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of alpha-galactosylceramide. Eur J Immunol (2001) 1.56

Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling. Oncogene (2009) 1.54

An antitumor promoter from Moringa oleifera Lam. Mutat Res (1999) 1.54

Estrogenicity of fissure sealants and adhesive resins determined by reporter gene assay. J Dent Res (2000) 1.53

A reverse-sandwich ELISA for IgG antibody to a pollen allergen. J Allergy Clin Immunol (1988) 1.52

Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP. J Biol Chem (1999) 1.52

Analysis of the galactose signal transduction pathway in Saccharomyces cerevisiae: interaction between Gal3p and Gal80p. Mol Cell Biol (1996) 1.51

An intestinal bacterial metabolite of ginseng protopanaxadiol saponins has the ability to induce apoptosis in tumor cells. Biochem Biophys Res Commun (1998) 1.47

Orally active antioxidative copper(II) aspirinate: synthesis, structure characterization, superoxide scavenging activity, and in vitro and in vivo antioxidative evaluations. J Biol Inorg Chem (2005) 1.47

Arrhythmogenic right ventricular cardiomyopathy with an initial manifestation of severe left ventricular impairment and normal contraction of the right ventricle. Jpn Circ J (2000) 1.46

Gender-related differences in cocaine toxicity in the rat. J Lab Clin Med (1993) 1.46

Activity of neurones in the paraventricular nucleus of the hypothalamus and its control. J Physiol (1966) 1.42

Does nafamostat mesilate inhibit the tissue factor pathway? Thromb Res (1994) 1.40

Endoscopic ligation for ruptured duodenal varices. Am J Gastroenterol (1995) 1.40

Bone mineral density in patients with hyperthyroidism measured by dual energy X-ray absorptiometry. Clin Endocrinol (Oxf) (1993) 1.40

Inhibitory effects of maternal smoking on the development of severe retinopathy of prematurity. Eye (Lond) (2009) 1.40

The phytotoxicity to tobacco plants of short-chain carboxylic acids at atmospheric concentration levels in urban areas. Environ Technol (2001) 1.39

Granular lymphocyte proliferative disorder after autologous peripheral blood stem cell transplantation for multiple myeloma. Eur J Haematol (2003) 1.39

Anomalously hindered E2 strength B(E2;2+(1)-->0+) in 16C. Phys Rev Lett (2004) 1.39

Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. Proc Natl Acad Sci U S A (1999) 1.39

Screening the p53 status of human cell lines using a yeast functional assay. Mol Carcinog (1997) 1.38

Anterofrontal superficial temporal artery island flap for full-thickness eyelid reconstruction. Ann Plast Surg (1989) 1.38

Constituents of the Vietnamese medicinal plant Orthosiphon stamineus. Chem Pharm Bull (Tokyo) (2000) 1.38

Production and properties of Toxoplasma growth inhibitory factor (Toxo-GIF) and interferon (IFN) in the lymphokines and the circulation of Toxoplasma immune mice. Zentralbl Bakteriol Mikrobiol Hyg A (1981) 1.37

Increased urinary beta 2-microglobulin in cadmium exposure: dose-effect relationship and biological significance of beta 2-microglobulin. Environ Health Perspect (1979) 1.37

Circular dystrophin RNAs consisting of exons that were skipped by alternative splicing. Hum Mol Genet (1999) 1.35

Adjuvant activity of diesel-exhaust particulates for the production of IgE antibody in mice. J Allergy Clin Immunol (1986) 1.35

Electrical activity in the supraoptic and paraventricular nuclei associated with neurohypophysial hormone release. J Physiol (1969) 1.34

Diffusion-weighted MR imaging of the hippocampus and temporal white matter in Alzheimer's disease. J Neurol Sci (1998) 1.33

Studies of antidromically identified neurosecretory cells of the hypothalamus by intracellular and extracellular recordings. J Physiol (1972) 1.33

Structural and immunochemical studies of teichoic acid of Listeria monocytogenes. J Biochem (1983) 1.29

Branching morphogenesis independent of mesenchymal-epithelial contact in the developing kidney. Proc Natl Acad Sci U S A (1999) 1.27

Disruption of the splicing enhancer sequence within exon 27 of the dystrophin gene by a nonsense mutation induces partial skipping of the exon and is responsible for Becker muscular dystrophy. J Clin Invest (1997) 1.27

New compressed tablet rapidly disintegrating in saliva in the mouth using crystalline cellulose and a disintegrant. Biol Pharm Bull (1995) 1.26

Effect of localization of missense mutations in SCN1A on epilepsy phenotype severity. Neurology (2004) 1.26

Inhibition of tumor angiogenesis and metastasis by a saponin of Panax ginseng, ginsenoside-Rb2. Biol Pharm Bull (1994) 1.26

Mesp2 initiates somite segmentation through the Notch signalling pathway. Nat Genet (2000) 1.25

Age-related valvular regurgitation: a study by pulsed Doppler echocardiography. Circulation (1987) 1.25

Accommodative reactions of neuronal elements in the spinal cord. J Neurophysiol (1966) 1.24

Pathophysiological analysis of combined burn and smoke inhalation injuries in sheep. Am J Physiol Lung Cell Mol Physiol (2001) 1.23

Protein phosphatase 2A interacts with and directly dephosphorylates RelA. J Biol Chem (2001) 1.23

Prediction of pulmonary arterial pressure in adults by pulsed Doppler echocardiography. Am J Cardiol (1986) 1.23

Oxygen-dependent perturbation of life span and aging rate in the nematode. J Gerontol (1993) 1.23

A new antifungal antibiotic, trichostatin. J Antibiot (Tokyo) (1976) 1.22

Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis. Mech Dev (2001) 1.22

Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice. J Clin Invest (1999) 1.21

Staged in vitro reconstitution and implantation of engineered rat kidney tissue. Proc Natl Acad Sci U S A (2007) 1.20

Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice. Br J Cancer (1999) 1.20

Detection of K-ras mutations in DNAs isolated from feces of patients with colorectal tumors by mutant-allele-specific amplification (MASA). Oncogene (1995) 1.20

Chemical analysis of diesel engine nanoparticles using a nano-DMA/thermal desorption particle beam mass spectrometer. Environ Sci Technol (2001) 1.19

Immunological activity of chitin and its derivatives. Vaccine (1984) 1.19

Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol (2000) 1.19

Deficiency in protein L-isoaspartyl methyltransferase results in a fatal progressive epilepsy. J Neurosci (1998) 1.19

A new human diploid cell strain, TIG-1, for the research on cellular aging. Exp Gerontol (1980) 1.18

Structures and biological activities of peptidoglycans of Listeria monocytogenes and Propionibacterium acnes. J Biochem (1982) 1.18

A rat model of human T lymphocyte virus type I (HTLV-I) infection. 1. Humoral antibody response, provirus integration, and HTLV-I-associated myelopathy/tropical spastic paraparesis-like myelopathy in seronegative HTLV-I carrier rats. J Exp Med (1992) 1.18

A nationwide survey on organic solvent components in various solvent products: Part 1. Homogeneous products such as thinners, degreasers and reagents. Ind Health (1983) 1.18

Diesel-exhaust particulates inoculated by the intranasal route have an adjuvant activity for IgE production in mice. J Allergy Clin Immunol (1987) 1.17

New screening methods for chemicals with hormonal activities using interaction of nuclear hormone receptor with coactivator. Toxicol Appl Pharmacol (1999) 1.16

A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction. Blood (2000) 1.16

Vitrectomy for rhegmatogenous or tractional retinal detachment with familial exudative vitreoretinopathy. Ophthalmology (1999) 1.16

Primary carcinoid of the testis associated with carcinoid syndrome. Int J Urol (2001) 1.16

Disruption of the uptake hydrogenase gene, but not of the bidirectional hydrogenase gene, leads to enhanced photobiological hydrogen production by the nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120. Appl Microbiol Biotechnol (2002) 1.16

Branching morphogenesis during kidney development. Annu Rev Physiol (2000) 1.15

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers. Oncogene (2012) 1.15

Phosphatidylinositol 3-kinase is involved in the protection of primary cultured human erythroid precursor cells from apoptosis. Blood (1999) 1.14

Cloning of the Drosophila prospero gene and its expression in ganglion mother cells. Biochem Biophys Res Commun (1992) 1.14

Cloning of mRNA sequence coding for sex-specific storage protein of Bombyx mori. Biochim Biophys Acta (1988) 1.13

Reciprocal and non-reciprocal action of the vagal and sympathetic nerves innervating the heart. J Auton Nerv Syst (1979) 1.13

Identification of temperature-sensitive dnaD mutants of Staphylococcus aureus that are defective in chromosomal DNA replication. Mol Genet Genomics (2004) 1.13

Electrical activity recorded from the pituitary stalk of the cat. Am J Physiol (1966) 1.12

Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13. Clin Exp Metastasis (1995) 1.12

Expression of transforming growth factor-beta 1 and its relation to endomysial fibrosis in progressive muscular dystrophy. Am J Pathol (1994) 1.12

Biosynthesis of archaeosine, a novel derivative of 7-deazaguanosine specific to archaeal tRNA, proceeds via a pathway involving base replacement on the tRNA polynucleotide chain. J Biol Chem (1997) 1.12

In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol Res (1997) 1.12

Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase. J Med Chem (2000) 1.12

Change in bone mineral density in patients with hyperthyroidism after attainment of euthyroidism by dual energy X-ray absorptiometry. Thyroid (1994) 1.10

Capsular polysaccharides of nongroupable streptococci that cross-react with pneumococcal group 19. J Immunol (1984) 1.10

Paraoxonase gene polymorphisms and plasma oxidized low-density lipoprotein level as possible risk factors for exudative age-related macular degeneration. Am J Ophthalmol (2001) 1.10

Epidemiological and outcome characteristics of major burns in Tokyo. Burns (2005) 1.10

Inhibition of HIV-1 infection by zinc group metal compounds. Antiviral Res (1999) 1.09