PubRank

Francesco Trapasso

Author PubWeight™ 62.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Familial cancer associated with a polymorphism in ARLTS1. N Engl J Med 2005 3.35
2 Concern Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27. Proc Natl Acad Sci U S A 2003 2.52
3 Targeted deletion of Wwox reveals a tumor suppressor function. Proc Natl Acad Sci U S A 2007 2.37
4 WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function. Cancer Res 2005 1.91
5 Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. Proc Natl Acad Sci U S A 2004 1.91
6 Concern WWOX gene restoration prevents lung cancer growth in vitro and in vivo. Proc Natl Acad Sci U S A 2005 1.84
7 Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. Cancer Res 2006 1.71
8 Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma. Cancer Res 2002 1.62
9 Loss of WWOX expression in gastric carcinoma. Clin Cancer Res 2004 1.55
10 The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis. Clin Cancer Res 2004 1.45
11 WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer. Cancer Res 2003 1.42
12 Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma. Cancer Res 2003 1.34
13 Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies. Mol Cancer Res 2003 1.32
14 Physical association with WWOX suppresses c-Jun transcriptional activity. Cancer Res 2006 1.21
15 Fhit tumor suppressor: guardian of the preneoplastic genome. Future Oncol 2008 1.21
16 Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma. Mol Cell Biol 2003 1.20
17 Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic. Proc Natl Acad Sci U S A 2003 1.09
18 The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue. Oncogene 2005 1.08
19 The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis. Oncogene 2004 1.08
20 Regression of upper gastric cancer in mice by FHIT gene delivery. FASEB J 2003 1.06
21 HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody. Mol Cell 2012 1.05
22 Knockout mice reveal a tumor suppressor function for Testin. Proc Natl Acad Sci U S A 2005 1.04
23 FEZ1/LZTS1 is down-regulated in high-grade bladder cancer, and its restoration suppresses tumorigenicity in transitional cell carcinoma cells. Am J Pathol 2002 1.03
24 Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor. J Biol Chem 2006 1.02
25 Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer. Cancer Res 2003 0.99
26 An adenovirus carrying the rat protein tyrosine phosphatase eta suppresses the growth of human thyroid carcinoma cell lines in vitro and in vivo. Cancer Res 2003 0.99
27 The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins. Cancer Res 2006 0.98
28 Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines. Cancer Res 2003 0.98
29 Molecular parameters of genome instability: roles of fragile genes at common fragile sites. J Cell Biochem 2008 0.96
30 Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies. Blood 2011 0.96
31 BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo. Clin Cancer Res 2008 0.91
32 MicroRNAs in mouse models of lymphoid malignancies. J Nucleic Acids Investig 2010 0.90
33 Fhit modulates the DNA damage checkpoint response. Cancer Res 2006 0.89
34 Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma. Clin Cancer Res 2003 0.89
35 The role of microRNAs in cancer susceptibility. Biomed Res Int 2013 0.87
36 Tumor suppressor functions of ARLTS1 in lung cancers. Cancer Res 2007 0.87
37 ARLTS1 - a novel tumor suppressor gene. Cancer Lett 2008 0.86
38 The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes and cell localization. J Biochem 2009 0.86
39 Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel. PLoS One 2013 0.84
40 Natural history and clinical response: "it's the virus, stupid, or is it the host?". BMC Infect Dis 2012 0.84
41 Role of PTPRJ genotype in papillary thyroid carcinoma risk. Endocr Relat Cancer 2010 0.83
42 Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation. ACS Chem Biol 2013 0.83
43 Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity. ACS Chem Biol 2012 0.83
44 Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties. ChemMedChem 2010 0.82
45 Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses. Curr Gene Ther 2004 0.81
46 Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328. FEBS J 2012 0.81
47 In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold. J Chem Inf Model 2014 0.81
48 Thymosin beta-10 protein synthesis suppression reduces the growth of human thyroid carcinoma cells in semisolid medium. Thyroid 2002 0.81
49 Cloning and molecular characterization of a novel gene strongly induced by the adenovirus E1A gene in rat thyroid cells. Oncogene 2003 0.80
50 Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35. Clin Cancer Res 2006 0.80
51 Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands. Bioorg Med Chem 2011 0.80
52 SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation. Cell Physiol Biochem 2015 0.79
53 Interleukin 27 polymorphisms in HCV RNA positive patients: is there an impact on response to interferon therapy? BMC Infect Dis 2014 0.77
54 Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas. Blood 2012 0.76
55 The role of G-CSF in the treatment of advanced tumors. Cancer Biol Ther 2009 0.75
56 Identification of a new mutation in the gene coding for hairless protein responsible for alopecia universalis: The importance of direct gene sequencing. Dermatol Online J 2011 0.75
57 Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells. J Biol Chem 2017 0.75