Published in Pediatrics on May 01, 2005
The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years. Gut (2009) 4.01
Heritability of nonalcoholic fatty liver disease. Gastroenterology (2009) 3.17
Cardiovascular risk factors and the metabolic syndrome in pediatric nonalcoholic fatty liver disease. Circulation (2008) 2.70
Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004. Gastroenterology (2007) 2.22
Presence of the metabolic syndrome in obese adolescents predicts impaired glucose tolerance and nonalcoholic fatty liver disease. J Adolesc Health (2008) 2.16
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Ethnicity and nonalcoholic fatty liver disease. Hepatology (2012) 1.98
Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988-1994 to 2007-2010. J Pediatr (2012) 1.72
Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents. PLoS One (2007) 1.66
Nonalcoholic fatty liver disease, liver fibrosis, and cardiometabolic risk factors in adolescence: a cross-sectional study of 1874 general population adolescents. J Clin Endocrinol Metab (2014) 1.55
Cytokeratin 18, a marker of cell death, is increased in children with suspected nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr (2008) 1.54
Paediatric gastroenterology evaluation of overweight and obese children referred from primary care for suspected non-alcoholic fatty liver disease. Aliment Pharmacol Ther (2013) 1.44
Hyperferritinemia and hyperuricemia may be associated with liver function abnormality in obese adolescents. PLoS One (2012) 1.41
Pediatric non alcoholic fatty liver disease: old and new concepts on development, progression, metabolic insight and potential treatment targets. BMC Pediatr (2013) 1.32
Chronic liver disease in the Hispanic population of the United States. Clin Gastroenterol Hepatol (2011) 1.30
Symptoms and quality of life in obese children and adolescents with non-alcoholic fatty liver disease. Aliment Pharmacol Ther (2009) 1.20
Pediatric nonalcoholic fatty liver disease: a multidisciplinary approach. Nat Rev Gastroenterol Hepatol (2012) 1.19
Relationship between alanine aminotransferase levels and metabolic syndrome in nonalcoholic fatty liver disease. J Zhejiang Univ Sci B (2008) 1.13
Drug metabolism alterations in nonalcoholic fatty liver disease. Drug Metab Rev (2011) 1.07
Non-alcoholic fatty liver disease: An early mediator predicting metabolic syndrome in obese children? World J Gastroenterol (2011) 1.03
Developmental origins of nonalcoholic fatty liver disease. Pediatr Res (2013) 1.03
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Nonalcoholic fatty liver disease as a comorbidity of childhood obesity. Ped Health (2009) 0.96
Pediatric nonalcoholic fatty liver disease: overview with emphasis on histology. World J Gastroenterol (2010) 0.96
Overview of screening methods for fatty liver disease in children. World J Hepatol (2012) 0.95
The association of elevated alanine aminotransferase and the metabolic syndrome in an overweight and obese pediatric population of multi-ethnic origin. Eur J Pediatr (2008) 0.94
A maternal "junk food" diet in pregnancy and lactation promotes nonalcoholic Fatty liver disease in rat offspring. Endocrinology (2010) 0.94
Gender-related variations in iron metabolism and liver diseases. World J Hepatol (2010) 0.94
Managing nonalcoholic fatty liver disease: recommendations for family physicians. Can Fam Physician (2007) 0.93
Childhood obesity for pediatric gastroenterologists. J Pediatr Gastroenterol Nutr (2013) 0.93
The relationship between pediatric nonalcoholic fatty liver disease and cardiovascular risk factors and increased risk of atherosclerosis in obese children. Pediatr Cardiol (2012) 0.92
Physical activity and nutrition attitudes in obese Hispanic children with non-alcoholic steatohepatitis. World J Gastroenterol (2011) 0.91
Suspected nonalcoholic Fatty liver disease is not associated with vitamin d status in adolescents after adjustment for obesity. J Obes (2011) 0.90
Pediatric fatty liver disease: role of ethnicity and genetics. World J Gastroenterol (2014) 0.90
Gender difference of alanine aminotransferase elevation may be associated with higher hemoglobin levels among male adolescents. PLoS One (2010) 0.89
Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents. World J Gastroenterol (2009) 0.87
Accuracy of computer-aided ultrasound as compared with magnetic resonance imaging in the evaluation of nonalcoholic fatty liver disease in obese and eutrophic adolescents. Radiol Bras (2015) 0.86
Prevalence of non-alcoholic fatty liver and characteristics in overweight adolescents in the general population. Eur J Epidemiol (2007) 0.85
Fatty liver disease in children: eat now pay later. Hepatol Int (2010) 0.85
Influence of elevated liver fat on circulating adipocytokines and insulin resistance in obese Hispanic adolescents. Pediatr Obes (2012) 0.84
Risk Score Model for Predicting Sonographic Non-alcoholic Fatty Liver Disease in Children and Adolescents. Iran J Pediatr (2011) 0.84
Differential effect of gender on hepatic fat. Pediatr Radiol (2011) 0.83
Ethnicity and nonalcoholic fatty liver disease in an obesity clinic: the impact of triglycerides. Dig Dis Sci (2008) 0.83
Steatosis and steatohepatitis: complex disorders. Int J Mol Sci (2014) 0.83
Ethnic differences in the link between insulin resistance and elevated ALT. Pediatrics (2013) 0.82
Sexually dimorphic genome-wide binding of retinoid X receptor alpha (RXRα) determines male-female differences in the expression of hepatic lipid processing genes in mice. PLoS One (2013) 0.82
Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. JAMA Pediatr (2016) 0.82
Serum alanine aminotransferase and its association with metabolic syndrome in children: the bogalusa heart study. Metab Syndr Relat Disord (2011) 0.81
Alanine aminotransferase elevation in obese infants and children: a marker of early onset non alcoholic Fatty liver disease. Hepat Mon (2014) 0.81
Ethnicity and elevated liver transaminases among newly diagnosed children with type 2 diabetes. BMC Pediatr (2012) 0.80
Therapeutic strategies for pediatric non-alcoholic fatty liver disease: a challenge for health care providers. World J Gastroenterol (2007) 0.80
Anthropometric and metabolic characteristics in children with clinically diagnosed nonalcoholic fatty liver disease. Paediatr Child Health (2008) 0.80
Prevalence of cardiometabolic risk factors and metabolic syndrome in obese Kuwaiti adolescents. Diabetes Metab Syndr Obes (2014) 0.80
Low LDL-C and high HDL-C levels are associated with elevated serum transaminases amongst adults in the United States: a cross-sectional study. PLoS One (2014) 0.79
Body weight has no impact on self-esteem of minority children living in inner city, low-income neighborhoods: a cross-sectional study. BMC Pediatr (2014) 0.79
Amount of hepatic fat predicts cardiovascular risk independent of insulin resistance among Hispanic-American adolescents. Lipids Health Dis (2015) 0.79
Consequences of obesity and weight loss: a devil's advocate position. Obes Rev (2014) 0.78
Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents. J Nutr Metab (2013) 0.78
Metabolic predictors for early identification of fatty liver using doppler and B-mode ultrasonography in overweight and obese adolescents. Eur J Pediatr (2010) 0.78
Longitudinal effects of MRI-measured hepatic steatosis on biomarkers of glucose homeostasis and hepatic apoptosis in obese youth. Diabetes Care (2012) 0.78
Clinical features of pediatric nonalcoholic fatty liver disease: a need for increased awareness and a consensus for screening. Clin Pediatr (Phila) (2014) 0.78
Feasibility of and agreement between MR imaging and spectroscopic estimation of hepatic proton density fat fraction in children with known or suspected nonalcoholic fatty liver disease. Abdom Imaging (2015) 0.77
Normal limit for serum alanine aminotransferase level and distribution of metabolic factors in old population of kalaleh, iran. Hepat Mon (2013) 0.77
Liver disease among children in Hawai'i diagnosed with metabolic syndrome. Hawaii J Med Public Health (2013) 0.77
"Weighing the risk": Obesity and outcomes following liver transplantation. World J Hepatol (2015) 0.76
Caring for children with NAFLD and navigating their care into adulthood. Nat Rev Gastroenterol Hepatol (2015) 0.76
Composite prognostic models across the non-alcoholic fatty liver disease spectrum: Clinical application in developing countries. World J Hepatol (2015) 0.76
The effect of weight loss on pediatric nonalcoholic Fatty liver disease. ISRN Gastroenterol (2013) 0.75
Prevalence and risk factors for non-alcoholic fatty liver in children and youth with obesity. BMC Pediatr (2017) 0.75
Clinical significance of serum alanine aminotransferase and lifestyle intervention in children with nonalcoholic fatty liver disease. Korean J Pediatr (2016) 0.75
An Animal Model for the Juvenile Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. PLoS One (2016) 0.75
Pediatric Non-Alcoholic Fatty Liver Disease. J Med Biochem (2014) 0.75
Keratin 18, Apoptosis, and Liver Disease in Children. Curr Pediatr Rev (2011) 0.75
[Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents]. Rev Paul Pediatr (2015) 0.75
Waist-to-height ratio is more closely associated with alanine aminotransferase levels than body mass index and waist circumference among population-based children: a cross-sectional study in Japan. BMC Pediatr (2015) 0.75
Epidemiology and Natural History of NAFLD. J Med Biochem (2014) 0.75
Comparison of the Phenotype and Approach to Pediatric vs Adult Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology (2016) 0.75
Health Issues in Hispanic/Latino Youth. J Lat Psychol (2016) 0.75
Effect of concurrent training on risk factors and hepatic steatosis in obese adolescents. Rev Paul Pediatr (2013) 0.75
Genetic and clinical markers of elevated liver fat content in overweight and obese Hispanic children. Obesity (Silver Spring) (2013) 0.75
Anthropometric Indices in Adults: Which Is the Best Indicator to Identify Alanine Aminotransferase Levels? Int J Environ Res Public Health (2016) 0.75
Clinical characteristics of obese boys and girls in a high school: focused on abdominal fat indices, fatty liver and carotid intima-media thickness. Korean J Pediatr (2011) 0.75
Assessment of Cardiovascular Parameters in Obese Children and Adolescents with Non-Alcoholic Fatty Liver Disease. J Clin Res Pediatr Endocrinol (2015) 0.75
Probable NAFLD, by ALT levels, and diabetes among Filipino-American women. Diabetes Res Clin Pract (2007) 0.75
A Branched-Chain Amino Acid-Related Metabolic Signature Characterizes Obese Adolescents with Non-Alcoholic Fatty Liver Disease. Nutrients (2017) 0.75
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med (2010) 13.33
Prevalence of fatty liver in children and adolescents. Pediatrics (2006) 7.00
The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology (2012) 5.47
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci U S A (2010) 4.95
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature (2013) 4.94
Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology (2005) 4.21
Relaxation effects in the quantification of fat using gradient echo imaging. Magn Reson Imaging (2008) 4.13
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice. Genes Dev (2003) 3.58
Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T. Radiology (2009) 3.31
The ploidy conveyor of mature hepatocytes as a source of genetic variation. Nature (2010) 3.27
Heritability of nonalcoholic fatty liver disease. Gastroenterology (2009) 3.17
Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr (2006) 3.03
Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers. Hepatology (2004) 3.00
Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease. Hepatology (2010) 2.86
Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network. Hepatology (2009) 2.78
Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease. J Pediatr (2003) 2.77
Cardiovascular risk factors and the metabolic syndrome in pediatric nonalcoholic fatty liver disease. Circulation (2008) 2.70
Endpoints and clinical trial design for nonalcoholic steatohepatitis. Hepatology (2011) 2.44
Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. Radiology (2011) 2.42
Signaling molecules in nonfamilial pulmonary hypertension. N Engl J Med (2003) 2.36
Clinical correlates of histopathology in pediatric nonalcoholic steatohepatitis. Gastroenterology (2008) 2.33
Fatty liver: imaging patterns and pitfalls. Radiographics (2006) 2.21
Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. J Magn Reson Imaging (2009) 2.18
Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev (2011) 2.17
Low-dose vaporized cannabis significantly improves neuropathic pain. J Pain (2012) 2.13
Advances in pediatric nonalcoholic fatty liver disease. Hepatology (2009) 2.03
Pediatric nonalcoholic fatty liver disease: a critical appraisal of current data and implications for future research. J Pediatr Gastroenterol Nutr (2006) 1.97
Operative classification of thromboembolic disease determines outcome after pulmonary endarterectomy. J Thorac Cardiovasc Surg (2002) 1.96
Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse. J Am Coll Cardiol (2005) 1.85
Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD. J Pediatr Gastroenterol Nutr (2012) 1.82
Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology (2013) 1.77
Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs). Blood (2006) 1.75
Patients with biliary atresia have elevated direct/conjugated bilirubin levels shortly after birth. Pediatrics (2011) 1.75
Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology (2008) 1.65
The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Am J Gastroenterol (2012) 1.61
Sex-related differences in patients with severe head injury: greater susceptibility to brain swelling in female patients 50 years of age and younger. J Neurosurg (2003) 1.58
Understanding intestinal cysteamine bitartrate absorption. J Pediatr (2006) 1.57
Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. Gastroenterology (2013) 1.57
Two-year prospective study of major depressive disorder in HIV-infected men. J Affect Disord (2007) 1.56
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. Gastroenterology (2006) 1.55
Incident major depression does not affect neuropsychological functioning in HIV-infected men. J Int Neuropsychol Soc (2007) 1.54
Pseudo-hydrodynamic delivery of helper-dependent adenoviral vectors into non-human primates for liver-directed gene therapy. Mol Ther (2007) 1.50
Consequences of copper accumulation in the livers of the Atp7b-/- (Wilson disease gene) knockout mice. Am J Pathol (2006) 1.47
Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr (2015) 1.46
Rotavirus viremia and extraintestinal viral infection in the neonatal rat model. J Virol (2006) 1.43
Screening US for blunt abdominal trauma: objective predictors of false-negative findings and missed injuries. Radiology (2003) 1.43
The effect of cysteamine bitartrate on adiponectin multimerization in non-alcoholic fatty liver disease and healthy subjects. J Pediatr (2012) 1.42
Adeno-associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo. Hepatology (2010) 1.41
Successful liver transplantation in a child with severe portopulmonary hypertension treated with epoprostenol. J Pediatr Gastroenterol Nutr (2005) 1.40
Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primates. Mol Ther (2008) 1.40
Dietary fructose in nonalcoholic fatty liver disease. Hepatology (2013) 1.39
Severe dysplasia in children with familial adenomatous polyposis: rare or simply overlooked? J Pediatr Surg (2006) 1.38
Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector. Proc Natl Acad Sci U S A (2005) 1.36
Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology (2014) 1.32
Ploidy reductions in murine fusion-derived hepatocytes. PLoS Genet (2009) 1.28
Small cell undifferentiated variant of hepatoblastoma: adverse clinical and molecular features similar to rhabdoid tumors. Pediatr Blood Cancer (2009) 1.28
Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice. Hepatology (2010) 1.27
Neurocognitive functioning in acute or early HIV infection. J Neurovirol (2010) 1.27
Fibrolamellar hepatocellular carcinoma in children and adolescents. Cancer (2003) 1.25
Aneuploidy as a mechanism for stress-induced liver adaptation. J Clin Invest (2012) 1.23
Prediction of incident neurocognitive impairment by plasma HIV RNA and CD4 levels early after HIV seroconversion. Arch Neurol (2003) 1.22
Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients. J Pediatr Gastroenterol Nutr (2008) 1.21
Hepatic, cardiovascular, and endocrine outcomes of the histological subphenotypes of nonalcoholic fatty liver disease. Semin Liver Dis (2008) 1.20
Complete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the Children's Oncology Group. J Clin Oncol (2011) 1.19
Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates. Hum Gene Ther (2006) 1.18
Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis. J Clin Invest (2010) 1.17
Association between metabolic syndrome and liver histology among children with nonalcoholic Fatty liver disease. Am J Gastroenterol (2010) 1.17
Neurocognitive impact of substance use in HIV infection. J Acquir Immune Defic Syndr (2011) 1.16
A concise panel of biomarkers identifies neurocognitive functioning changes in HIV-infected individuals. J Neuroimmune Pharmacol (2013) 1.15
Nonalcoholic fatty liver disease in children. Curr Opin Clin Nutr Metab Care (2011) 1.14
aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues. Proc Natl Acad Sci U S A (2009) 1.13
Toll-like receptor 4-dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury. Hepatology (2012) 1.13
Cellular immunity to Epstein-Barr virus in liver transplant recipients treated with rituximab for post-transplant lymphoproliferative disease. Am J Transplant (2005) 1.13
Pharmacokinetics of cysteamine bitartrate following gastrointestinal infusion. Br J Clin Pharmacol (2007) 1.12
ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Dev Cell (2011) 1.12
Fcgamma receptor type IIIA polymorphisms influence treatment outcomes in patients with inflammatory arthritis treated with tumor necrosis factor alpha-blocking agents. Arthritis Rheum (2005) 1.12
Placebo in nonalcoholic steatohepatitis: insight into natural history and implications for future clinical trials. Clin Gastroenterol Hepatol (2008) 1.11
Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine. FASEB J (2012) 1.10
Group A rotavirus infection and age-dependent diarrheal disease in rats: a new animal model to study the pathophysiology of rotavirus infection. J Virol (2002) 1.10
Gene expression in Barrett's esophagus: laser capture versus whole tissue. Scand J Gastroenterol (2009) 1.09
Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors. Hum Pathol (2009) 1.09
Serum aminotransferase levels are associated with markers of hypoxia in patients with obstructive sleep apnea. Sleep (2008) 1.08
Treatment of unresectable and metastatic hepatoblastoma: a pediatric oncology group phase II study. J Clin Oncol (2002) 1.08
Fast break on the fat brake: mechanism of peroxisome proliferator-activated receptor-delta regulation of lipid accumulation in hepatocytes. Hepatology (2008) 1.08
The evaluation and treatment of gastrointestinal disease in children with cystinosis receiving cysteamine. J Pediatr (2003) 1.06
Further evidence for EpCAM as the gene for congenital tufting enteropathy. Am J Med Genet A (2010) 1.03
Differential effects of metformin and troglitazone on cardiovascular risk factors in patients with type 2 diabetes. Diabetes Care (2002) 1.03
Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein. Virology (2006) 1.02
Association between puberty and features of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol (2012) 1.01
Clinical Research Network launches TONIC trial for treatment of nonalcoholic fatty liver disease in children. J Pediatr Gastroenterol Nutr (2006) 1.01
Hep G2 is a hepatoblastoma-derived cell line. Hum Pathol (2009) 1.00
A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration. Hepatology (2013) 1.00
Esomeprazole therapy for gastric acid hypersecretion in children with cystinosis. Pediatr Nephrol (2005) 0.99
Liver biopsy in modern clinical practice: a pediatric point-of-view. Adv Anat Pathol (2012) 0.98
Blunt abdominal trauma: clinical value of negative screening US scans. Radiology (2004) 0.98