Published in Cell Cycle on April 16, 2005
Aberrant cell cycle and apoptotic changes characterise severe influenza A infection--a meta-analysis of genomic signatures in circulating leukocytes. PLoS One (2011) 1.09
Apoptin nucleocytoplasmic shuttling is required for cell type-specific localization, apoptosis, and recruitment of the anaphase-promoting complex/cyclosome to PML bodies. J Virol (2006) 1.00
DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin. J Virol (2011) 0.94
Network-based prediction and analysis of HIV dependency factors. PLoS Comput Biol (2011) 0.91
Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a. PLoS Pathog (2012) 0.90
Changing the ubiquitin landscape during viral manipulation of the DNA damage response. FEBS Lett (2011) 0.86
Control the host cell cycle: viral regulation of the anaphase-promoting complex. J Virol (2013) 0.84
EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells. Cell Commun Signal (2012) 0.81
Kaposi's sarcoma-associated herpesvirus-encoded LANA can induce chromosomal instability through targeted degradation of the mitotic checkpoint kinase Bub1. J Virol (2014) 0.81
Nonstructural protein σ1s mediates reovirus-induced cell cycle arrest and apoptosis. J Virol (2013) 0.80
Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis. Virology (2013) 0.79
A structural model of the anaphase promoting complex co-activator (Cdh1) and in silico design of inhibitory compounds. Res Pharm Sci (2015) 0.76
Anti-cancer effect of HIV-1 viral protein R on doxorubicin resistant neuroblastoma. PLoS One (2010) 0.76
Transcriptional regulatory elements in the human genome. Annu Rev Genomics Hum Genet (2006) 7.18
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell (2008) 6.84
A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell (2005) 4.32
Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nat Genet (2005) 4.15
Inappropriate gene activation in FSHD: a repressor complex binds a chromosomal repeat deleted in dystrophic muscle. Cell (2002) 3.56
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data. BMC Bioinformatics (2010) 3.47
An elaborate pathway required for Ras-mediated epigenetic silencing. Nature (2007) 3.47
Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs). RNA (2004) 3.16
Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly. Mol Cell (2004) 2.90
Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. Mol Cell (2005) 2.85
Depleting tumor-specific Tregs at a single site eradicates disseminated tumors. J Clin Invest (2013) 2.77
Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1. Nature (2005) 2.42
U2AF homology motifs: protein recognition in the RRM world. Genes Dev (2004) 2.34
RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans. Genes Dev (2006) 2.25
Differential requirement of SAGA components for recruitment of TATA-box-binding protein to promoters in vivo. Mol Cell Biol (2002) 2.16
Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol. PLoS One (2009) 2.11
A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly. Mol Cell (2004) 2.11
In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer. Genes Dev (2004) 1.99
Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell (2012) 1.98
F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage. Nature (2009) 1.93
A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production. Cell (2010) 1.85
Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65. Mol Cell (2006) 1.83
RS domain-splicing signal interactions in splicing of U12-type and U2-type introns. Nat Struct Mol Biol (2007) 1.67
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature (2010) 1.64
BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription. Blood (2011) 1.61
Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer Res (2009) 1.61
Systematic analysis of essential yeast TAFs in genome-wide transcription and preinitiation complex assembly. EMBO J (2003) 1.59
A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications. Nat Med (2010) 1.55
Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders. Blood (2011) 1.53
p53-dependent translational control of senescence and transformation via 4E-BPs. Cancer Cell (2009) 1.51
HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs. PLoS Biol (2005) 1.50
Deletion of the gene encoding G0/G 1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice. Diabetologia (2014) 1.49
Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature (2007) 1.47
Characterization of enhancer function from genome-wide analyses. Annu Rev Genomics Hum Genet (2012) 1.41
p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase. Science (2006) 1.40
Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome. J Mol Med (Berl) (2007) 1.40
TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed. Proc Natl Acad Sci U S A (2003) 1.34
A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene. Genes Dev (2008) 1.33
Crystal structure of UAP56, a DExD/H-box protein involved in pre-mRNA splicing and mRNA export. Structure (2004) 1.33
Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression. Mol Cell (2009) 1.31
The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing. Genes Dev (2010) 1.26
Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Genes Dev (2008) 1.25
Selective recruitment of TAFs by yeast upstream activating sequences. Implications for eukaryotic promoter structure. Curr Biol (2002) 1.25
Inhibition of apoptosis by ATFx: a novel role for a member of the ATF/CREB family of mammalian bZIP transcription factors. Genes Dev (2002) 1.24
A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2. RNA (2004) 1.14
A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. Elife (2014) 1.12
High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells. Blood (2013) 1.12
The viral protein Apoptin associates with the anaphase-promoting complex to induce G2/M arrest and apoptosis in the absence of p53. Genes Dev (2004) 1.11
Efficacy of IGFBP7 for treatment of metastatic melanoma and other cancers in mouse models and human cell lines. Mol Cancer Ther (2009) 1.10
Interaction of Gal4p with components of transcription machinery in vivo. Methods Enzymol (2003) 1.07
Transcription and signalling pathways involved in BCR-ABL-mediated misregulation of 24p3 and 24p3R. EMBO J (2009) 1.06
Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis. Dev Dyn (2009) 1.04
Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65. J Biol Chem (2008) 1.03
miR-146a promotes the initiation and progression of melanoma by activating Notch signaling. Elife (2014) 1.02
Role for IGFBP7 in senescence induction by BRAF. Cell (2010) 1.01
Apoptin nucleocytoplasmic shuttling is required for cell type-specific localization, apoptosis, and recruitment of the anaphase-promoting complex/cyclosome to PML bodies. J Virol (2006) 1.00
Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. Genes Dev (2013) 0.98
Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation. Nat Commun (2013) 0.98
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. Elife (2012) 0.97
The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells. Nat Genet (2012) 0.97
Transcriptional program of apoptosis induction following interleukin 2 deprivation: identification of RC3, a calcium/calmodulin binding protein, as a novel proapoptotic factor. Mol Cell Biol (2003) 0.96
Redirecting retroviral tropism by insertion of short, nondisruptive peptide ligands into envelope. J Virol (2002) 0.96
DNA damage response signaling triggers nuclear localization of the chicken anemia virus protein Apoptin. J Virol (2011) 0.94
Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons. Proc Natl Acad Sci U S A (2012) 0.93
Resistance to vemurafenib resulting from a novel mutation in the BRAFV600E kinase domain. Pigment Cell Melanoma Res (2013) 0.92
Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection. PLoS Genet (2007) 0.90
Functional analysis of TFIID components using conditional mutants. Methods Enzymol (2003) 0.89
Selective targeting and inducible destruction of human cancer cells by retroviruses with envelope proteins bearing short peptide ligands. J Virol (2002) 0.89
p53 inhibits angiogenesis by inducing the production of Arresten. Cancer Res (2012) 0.89
U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res (2013) 0.88
An activating transcription factor 5-mediated survival pathway as a target for cancer therapy? Oncotarget (2010) 0.88
A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. PLoS Genet (2012) 0.88
When enough is enough: genetic diseases associated with transcriptional derepression. Curr Opin Genet Dev (2004) 0.87
Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy. Expert Opin Ther Targets (2011) 0.86
Group A streptococcal meningitis: case report and review of the literature. J Infect (2005) 0.86
A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and recurrent high-grade gliomas. Int J Radiat Oncol Biol Phys (2012) 0.85
Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3. J Biol Chem (2011) 0.84
Structure of phosphorylated SF1 bound to U2AF⁶⁵ in an essential splicing factor complex. Structure (2012) 0.84
MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair. Mol Cell Biol (2013) 0.83
High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to Non-Hodgkin's lymphoma. Genes Chromosomes Cancer (2013) 0.83
Senescence induction in human fibroblasts and hematopoietic progenitors by leukemogenic fusion proteins. Blood (2010) 0.83
Isolation of High-Molecular-Weight DNA Using Organic Solvents. Cold Spring Harb Protoc (2017) 0.83
Localization and importance of the adenovirus E4orf4 protein during lytic infection. J Virol (2008) 0.82
GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2. Proc Natl Acad Sci U S A (2013) 0.82
hnRNP A1 contacts exon 5 to promote exon 6 inclusion of apoptotic Fas gene. Apoptosis (2013) 0.80
Adenovirus E4orf4 protein-induced death of p53-/- H1299 human cancer cells follows a G1 arrest of both tetraploid and diploid cells due to a failure to initiate DNA synthesis. J Virol (2013) 0.80
SC35 promotes splicing of the C5-V6-C6 isoform of CD44 pre-mRNA. Oncol Rep (2013) 0.80
Transcriptional derepression as a cause of genetic diseases. Curr Opin Genet Dev (2003) 0.80
Allele frequency differences of cytochrome P450 polymorphisms in a sample of New Zealand Māori. N Z Med J (2008) 0.79
Aberrant expression of the dendritic cell marker TNFAIP2 by the malignant cells of Hodgkin lymphoma and primary mediastinal large B-cell lymphoma distinguishes these tumor types from morphologically and phenotypically similar lymphomas. Am J Surg Pathol (2011) 0.79
Regulation of collagen-derived antiangiogenic factors by p53. Expert Opin Biol Ther (2008) 0.79
Oncogenic BRAF and the tumor suppressor IGFBP7 in the genesis of atypical spitzoid nevomelanocytic proliferations. J Cutan Pathol (2009) 0.78
Polypyrimidine tract binding protein inhibits IgM pre-mRNA splicing by diverting U2 snRNA base-pairing away from the branch point. RNA (2014) 0.78
Analysis of Gal4-directed transcription activation using Tra1 mutants selectively defective for interaction with Gal4. Proc Natl Acad Sci U S A (2012) 0.78
Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans. PLoS One (2013) 0.78
Genome-wide RNAi screening to identify regulators of oncogene-induced cellular senescence. Methods Mol Biol (2013) 0.77