Published in Circ Res on May 05, 2005
S-nitrosylation in cardiovascular signaling. Circ Res (2010) 3.02
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Mixed S-nitrosylated polymerized bovine hemoglobin species moderate hemodynamic effects in acutely hypoxic rats. Am J Respir Cell Mol Biol (2009) 0.81
Red cell physiology and signaling relevant to the critical care setting. Curr Opin Pediatr (2015) 0.80
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Transnitrosation signals oxyhemoglobin desaturation. Circ Res (2008) 0.77
Local and systemic vasodilatory effects of low molecular weight S-nitrosothiols. Free Radic Biol Med (2015) 0.76
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature (2006) 27.91
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Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell (2004) 6.99
Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity. Cancer Cell (2005) 5.75
Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes. JAMA (2004) 5.11
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Nitric oxide in the human respiratory cycle. Nat Med (2002) 4.50
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. J Natl Cancer Inst (2006) 4.27
Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell (2004) 3.98
Protein S-nitrosylation in health and disease: a current perspective. Trends Mol Med (2009) 3.75
Evolution of adverse changes in stored RBCs. Proc Natl Acad Sci U S A (2007) 3.58
Regulation of HIF-1alpha stability through S-nitrosylation. Mol Cell (2007) 3.50
Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med (2008) 3.38
Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin. Annu Rev Physiol (2005) 3.19
Protection from experimental asthma by an endogenous bronchodilator. Science (2005) 3.17
S-nitrosylation in cardiovascular signaling. Circ Res (2010) 3.02
Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development. J Biomed Opt (2005) 2.94
S-nitrosylation in health and disease. Trends Mol Med (2003) 2.85
Assessment and application of the biotin switch technique for examining protein S-nitrosylation under conditions of pharmacologically induced oxidative stress. J Biol Chem (2007) 2.85
OxyR: a molecular code for redox-related signaling. Cell (2002) 2.83
Randomized trial of hyperthermia and radiation for superficial tumors. J Clin Oncol (2005) 2.82
S-nitrosohemoglobin deficiency: a mechanism for loss of physiological activity in banked blood. Proc Natl Acad Sci U S A (2007) 2.77
Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. Nat Biotechnol (2009) 2.69
Identification of the enzymatic mechanism of nitroglycerin bioactivation. Proc Natl Acad Sci U S A (2002) 2.65
Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2. Cell (2007) 2.65
Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol (2009) 2.42
Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging. J Clin Oncol (2003) 2.35
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. J Clin Oncol (2008) 2.32
A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest (2003) 2.32
Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance. J Clin Invest (2004) 2.22
An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate. Proc Natl Acad Sci U S A (2006) 2.21
An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. Proc Natl Acad Sci U S A (2005) 2.18
Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment. Cancer Metastasis Rev (2007) 2.15
Basal and stimulated protein S-nitrosylation in multiple cell types and tissues. J Biol Chem (2002) 2.14
Endogenous S-nitrosothiols protect against myocardial injury. Proc Natl Acad Sci U S A (2009) 2.13
Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects. J Natl Cancer Inst (2007) 2.03
Nitric oxide regulates endocytosis by S-nitrosylation of dynamin. Proc Natl Acad Sci U S A (2006) 1.99
The shunt problem: control of functional shunting in normal and tumour vasculature. Nat Rev Cancer (2010) 1.97
Detection of protein S-nitrosylation with the biotin-switch technique. Free Radic Biol Med (2008) 1.95
NO/redox disequilibrium in the failing heart and cardiovascular system. J Clin Invest (2005) 1.94
Inhaled ethyl nitrite gas for persistent pulmonary hypertension of the newborn. Lancet (2002) 1.93
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S-nitrosothiol signaling in respiratory biology. Am J Respir Crit Care Med (2006) 1.84
Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy. AJR Am J Roentgenol (2003) 1.83
Routes to S-nitroso-hemoglobin formation with heme redox and preferential reactivity in the beta subunits. Proc Natl Acad Sci U S A (2003) 1.81
Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat. Cancer Res (2005) 1.81
Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs. J Natl Cancer Inst (2006) 1.79
S-nitrosylating agents: a novel class of compounds that increase cystic fibrosis transmembrane conductance regulator expression and maturation in epithelial cells. Mol Pharmacol (2006) 1.79
Site-specific analysis of protein S-acylation by resin-assisted capture. J Lipid Res (2010) 1.77
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell (2011) 1.77
Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study. Lancet Oncol (2007) 1.76
S-nitrosothiols in the blood: roles, amounts, and methods of analysis. Circ Res (2004) 1.76
Enzymes that counteract nitrosative stress promote fungal virulence. Curr Biol (2003) 1.75
Impaired vasodilation by red blood cells in sickle cell disease. Proc Natl Acad Sci U S A (2005) 1.74
Concern Protection from lipopolysaccharide-induced lung injury by augmentation of airway S-nitrosothiols. Am J Respir Crit Care Med (2009) 1.74
Recent progress in defining mechanisms and potential targets for prevention of normal tissue injury after radiation therapy. Int J Radiat Oncol Biol Phys (2005) 1.73
A dual-emissive-materials design concept enables tumour hypoxia imaging. Nat Mater (2009) 1.72
Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy. Clin Cancer Res (2006) 1.72
A novel rodent mammary window of orthotopic breast cancer for intravital microscopy. Microvasc Res (2003) 1.69
Regulation by S-nitrosylation of protein post-translational modification. J Biol Chem (2011) 1.68
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Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Sci Signal (2009) 1.66
TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice. J Clin Invest (2011) 1.66
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A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury. Free Radic Biol Med (2002) 1.65
S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking. Mol Cell (2008) 1.63
Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy. Clin Cancer Res (2005) 1.63
NOS2 regulation of NF-kappaB by S-nitrosylation of p65. J Biol Chem (2007) 1.62
Structural adaptation and heterogeneity of normal and tumor microvascular networks. PLoS Comput Biol (2009) 1.62
In vivo optical molecular imaging and analysis in mice using dorsal window chamber models applied to hypoxia, vasculature and fluorescent reporters. Nat Protoc (2011) 1.62
The pervasive presence of fluctuating oxygenation in tumors. Cancer Res (2008) 1.61
Maintenance of nitric oxide and redox homeostasis by the salmonella flavohemoglobin hmp. J Biol Chem (2006) 1.58
SU5416 delays wound healing through inhibition of TGF-beta 1 activation. Cancer Biol Ther (2002) 1.58
New insights into protein S-nitrosylation. Mitochondria as a model system. J Biol Chem (2004) 1.57
The SNO-proteome: causation and classifications. Curr Opin Chem Biol (2010) 1.56
A pilot Phase II trial of concurrent radiotherapy, chemotherapy, and hyperthermia for locally advanced cervical carcinoma. Cancer (2003) 1.56
Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation. Future Oncol (2010) 1.54
The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis. Proc Natl Acad Sci U S A (2006) 1.54
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. PLoS One (2012) 1.53
Green's function methods for analysis of oxygen delivery to tissue by microvascular networks. Ann Biomed Eng (2004) 1.52
Hyperthermia mediated liposomal drug delivery. Int J Hyperthermia (2006) 1.52
Acute effects of aerosolized S-nitrosoglutathione in cystic fibrosis. Am J Respir Crit Care Med (2002) 1.51
Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors. Cancer Res (2007) 1.51
Functional significance of Tie2 signaling in the adult vasculature. Recent Prog Horm Res (2004) 1.50
Expression of HIF-1alpha, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer. Lung Cancer (2005) 1.48
Erythropoietin biology in cancer. Clin Cancer Res (2006) 1.48
Requirements for T lymphocyte migration in explanted lymph nodes. J Immunol (2007) 1.48
A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness. Int J Radiat Oncol Biol Phys (2005) 1.48
Predicting radiotherapy-induced cardiac perfusion defects. Med Phys (2005) 1.47
Bioactivation of nitroglycerin by the mitochondrial aldehyde dehydrogenase. Trends Cardiovasc Med (2006) 1.47
ZD6126: a novel vascular-targeting agent that causes selective destruction of tumor vasculature. Cancer Res (2002) 1.47