Published in Cell Signal on December 15, 2004
Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells. Cell Signal (2007) 1.09
Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells. Cell Mol Immunol (2010) 1.08
Taxifolin suppresses UV-induced skin carcinogenesis by targeting EGFR and PI3K. Cancer Prev Res (Phila) (2012) 0.88
Preventive and prophylactic mechanisms of action of pomegranate bioactive constituents. Evid Based Complement Alternat Med (2013) 0.88
Satellite cells say NO to radiation. Radiat Res (2011) 0.82
Nitric oxide is a mediator of antiproliferative effects induced by proinflammatory cytokines on pancreatic beta cells. Mediators Inflamm (2013) 0.82
Role of pomegranate and citrus fruit juices in colon cancer prevention. World J Gastroenterol (2014) 0.82
Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts. J Biomed Sci (2015) 0.81
Upregulation of fibronectin expression by COX-2 is mediated by interaction with ELMO1. Cell Signal (2010) 0.79
Activation of PI3K in response to high glucose leads to regulation of SOCS-3 and STAT1/3 signals and induction of glomerular mesangial extracellular matrix formation. Oncotarget (2017) 0.75
Dichloromethane fraction of Laminaria japonica ethanolic extract inhibits lipopolysaccharide-induced nitric oxide synthase and cyclooxygenase-2 expression in RAW 264.7 cells via NF-κB pathway. Inflammation (2012) 0.75
Islet-like clusters derived from mesenchymal stem cells in Wharton's Jelly of the human umbilical cord for transplantation to control type 1 diabetes. PLoS One (2008) 1.70
High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell Signal (2005) 1.43
The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo. Diabetes (2006) 1.23
High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway. Arterioscler Thromb Vasc Biol (2005) 1.22
Hyperglycemia enhances adipogenic induction of lipid accumulation: involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor gamma signaling. Endocrinology (2007) 1.18
Signal transduction for inhibition of inducible nitric oxide synthase and cyclooxygenase-2 induction by capsaicin and related analogs in macrophages. Br J Pharmacol (2003) 1.12
Heavy metals, islet function and diabetes development. Islets (2010) 1.08
Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kappaB activation and cyclooxygenase-2 expression in mesangial cells. Mol Pharmacol (2004) 1.03
Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis. Free Radic Biol Med (2008) 1.02
Extract of lotus leaf ( Nelumbo nucifera ) and its active constituent catechin with insulin secretagogue activity. J Agric Food Chem (2011) 0.99
Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth. PLoS One (2007) 0.97
Inorganic arsenic causes cell apoptosis in mouse cerebrum through an oxidative stress-regulated signaling pathway. Arch Toxicol (2011) 0.95
Methylmercury induces pancreatic beta-cell apoptosis and dysfunction. Chem Res Toxicol (2006) 0.95
IL-13 downregulates PPAR-gamma/heme oxygenase-1 via ER stress-stimulated calpain activation: aggravation of activated microglia death. Cell Mol Life Sci (2010) 0.92
Mite allergen Der-p2 triggers human B lymphocyte activation and Toll-like receptor-4 induction. PLoS One (2011) 0.91
HMG-CoA reductase inhibitors activate caspase-1 in human monocytes depending on ATP release and P2X7 activation. J Leukoc Biol (2012) 0.91
Inorganic mercury causes pancreatic beta-cell death via the oxidative stress-induced apoptotic and necrotic pathways. Toxicol Appl Pharmacol (2009) 0.88
Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes. J Orthop Res (2013) 0.88
Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis. Shock (2012) 0.87
Arsenic and diabetes: current perspectives. Kaohsiung J Med Sci (2011) 0.86
EGb 761 (Ginkgo biloba) protects cochlear hair cells against ototoxicity induced by gentamicin via reducing reactive oxygen species and nitric oxide-related apoptosis. J Nutr Biochem (2010) 0.86
Benzo[a]pyrene regulates osteoblast proliferation through an estrogen receptor-related cyclooxygenase-2 pathway. Chem Res Toxicol (2004) 0.85
Uropathogenic Escherichia coli-induced inflammation alters mouse urinary bladder contraction via an interleukin-6-activated inducible nitric oxide synthase-related pathway. Infect Immun (2009) 0.84
A novel human stem cell coculture system that maintains the survival and function of culture islet-like cell clusters. Cell Transplant (2008) 0.83
Salubrinal, an eIF2α dephosphorylation inhibitor, enhances cisplatin-induced oxidative stress and nephrotoxicity in a mouse model. Free Radic Biol Med (2011) 0.83
Bladder instillation of Escherichia coli lipopolysaccharide alters the muscle contractions in rat urinary bladder via a protein kinase C-related pathway. Toxicol Appl Pharmacol (2005) 0.83
Epidemiology of Blastocystis hominis and other intestinal parasites among the immigrant population in northeastern Taiwan by routine physical examination for residence approval. J Microbiol Immunol Infect (2009) 0.83
Involvement of caspase-12-dependent apoptotic pathway in ionic radiocontrast urografin-induced renal tubular cell injury. Toxicol Appl Pharmacol (2012) 0.82
Proinflammatory effects of LIGHT through HVEM and LTbetaR interactions in cultured human umbilical vein endothelial cells. J Biomed Sci (2005) 0.82
EGb761 inhibits inflammatory responses in human chondrocytes and shows chondroprotection in osteoarthritic rat knee. J Orthop Res (2013) 0.81
Honokiol rescues sepsis-associated acute lung injury and lethality via the inhibition of oxidative stress and inflammation. Intensive Care Med (2011) 0.81
Involvement of nitric oxide generation in noise-induced temporary threshold shift in guinea pigs. Hear Res (2005) 0.80
Evaluation of osteoporosis prevention by adlay using a tissue culture model. Asia Pac J Clin Nutr (2008) 0.79
Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs. Bioorg Med Chem (2005) 0.79
Extract isolated from Angelica hirsutiflora with insulin secretagogue activity. J Ethnopharmacol (2009) 0.78
Effects of methylprednisolone on nitric oxide formation and survival of facial motor neurons after axotomy. Brain Res (2008) 0.77
Chronologic changes of nitric oxide concentration in the cochlear lateral wall and its role in noise-induced permanent threshold shift. Laryngoscope (2008) 0.75
Impact of activities of Na(+)-K(+)-ATPase and Ca2(+)-ATPase in the cochlear lateral wall on recovery from noise-induced temporary threshold shift. Ann Otol Rhinol Laryngol (2002) 0.75
Titanium implants enhance pulmonary nitric oxide production and lung injury in rats exposed to endotoxin. J Biomed Mater Res A (2004) 0.75
Titanium implants alter endothelial function and vasoconstriction via a protein kinase C-regulated pathway. Acta Biomater (2009) 0.75