Published in Nat Neurosci on May 15, 2005
The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels. Br J Pharmacol (2013) 1.88
E-I balance and human diseases - from molecules to networking. Front Mol Neurosci (2008) 1.29
Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy. J Cell Mol Med (2008) 1.18
Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis. Neurobiol Dis (2010) 1.11
Changes in neural network homeostasis trigger neuropsychiatric symptoms. J Clin Invest (2014) 1.06
GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. J Physiol (2007) 1.05
Inhibitory glycine receptors: an update. J Biol Chem (2012) 1.02
The glycinergic system in human startle disease: a genetic screening approach. Front Mol Neurosci (2010) 1.02
Allosteric modulation of glycine receptors. Br J Pharmacol (2011) 1.01
Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing. Front Mol Neurosci (2009) 1.01
Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. J Clin Invest (2012) 0.97
Alternative splicing and extensive RNA editing of human TPH2 transcripts. PLoS One (2010) 0.97
Defective glycinergic synaptic transmission in zebrafish motility mutants. Front Mol Neurosci (2010) 0.88
Extrasynaptic and postsynaptic receptors in glycinergic and GABAergic neurotransmission: a division of labor? Front Mol Neurosci (2008) 0.88
Estrogen in cycling rats alters gene expression in the temporomandibular joint, trigeminal ganglia and trigeminal subnucleus caudalis/upper cervical cord junction. J Cell Physiol (2011) 0.87
Membrane distribution of the glycine receptor α3 studied by optical super-resolution microscopy. Histochem Cell Biol (2014) 0.87
Presynaptic mechanisms of neuronal plasticity and their role in epilepsy. Front Cell Neurosci (2014) 0.86
Zinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol. Alcohol Clin Exp Res (2013) 0.85
Direct and indirect control of orexin/hypocretin neurons by glycine receptors. J Physiol (2010) 0.84
Functional hallmarks of GABAergic synapse maturation and the diverse roles of neurotrophins. Front Cell Neurosci (2011) 0.84
Glycine receptor in rat hippocampal and spinal cord neurons as a molecular target for rapid actions of 17-beta-estradiol. Mol Pain (2009) 0.83
The Biochemistry and Epigenetics of Epilepsy: Focus on Adenosine and Glycine. Front Mol Neurosci (2016) 0.82
Comparing methods of detection and quantitation of RNA editing of rat glycine receptor alpha3. Int J Biol Sci (2008) 0.82
Glycine receptor mutants of the mouse: what are possible routes of inhibitory compensation? Front Mol Neurosci (2012) 0.82
Post-transcriptional control of Na,K-ATPase activity and cell growth by a splice variant of FXYD2 protein with modified mRNA. J Biol Chem (2011) 0.81
Glycine transporter 1 is a target for the treatment of epilepsy. Neuropharmacology (2015) 0.80
Generation of Functional Inhibitory Synapses Incorporating Defined Combinations of GABA(A) or Glycine Receptor Subunits. Front Mol Neurosci (2015) 0.79
Activation of glycine receptors modulates spontaneous epileptiform activity in the immature rat hippocampus. J Physiol (2014) 0.78
4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance. Br J Pharmacol (2014) 0.78
Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain. Cell Death Dis (2015) 0.78
Molecular architecture of glycinergic synapses. Histochem Cell Biol (2008) 0.77
Parallel Evolution and Lineage-Specific Expansion of RNA Editing in Ctenophores. Integr Comp Biol (2015) 0.77
A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABAAR and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing. Front Mol Neurosci (2016) 0.75
The Intracellular Loop of the Glycine Receptor: It's not all about the Size. Front Mol Neurosci (2016) 0.75
RNA Editing-Systemic Relevance and Clue to Disease Mechanisms? Front Mol Neurosci (2016) 0.75
Presence of ethanol sensitive glycine receptors in medium spiny neurons in the mouse nucleus accumbens. J Physiol (2017) 0.75
Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain. Proc Natl Acad Sci U S A (2017) 0.75
Hippocampal Characteristics and Invariant Sequence Elements Distribution of GLRA2 and GLRA3 C-to-U Editing. Mol Syndromol (2016) 0.75
Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science (2004) 15.91
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol Dis (2006) 5.96
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol (2007) 4.60
Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex. J Neurosci (2004) 3.17
NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex. Nat Cell Biol (2003) 3.09
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell (2007) 3.06
Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action. Antimicrob Agents Chemother (2002) 2.98
The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus. J Neurosci (2006) 2.85
TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis. Brain (2006) 2.80
Highly effective SNP-based association mapping and management of recessive defects in livestock. Nat Genet (2008) 2.68
Induction of sharp wave-ripple complexes in vitro and reorganization of hippocampal networks. Nat Neurosci (2005) 2.56
Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin. Neuron (2009) 2.44
PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum Mol Genet (2010) 2.30
Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A). Hum Mutat (2007) 2.24
High-frequency network oscillations in cerebellar cortex. Neuron (2008) 2.12
Gephyrin: where do we stand, where do we go? Trends Neurosci (2008) 2.10
Glycine receptor autoimmune spectrum with stiff-man syndrome phenotype. JAMA Neurol (2013) 2.10
Differential involvement of oriens/pyramidale interneurones in hippocampal network oscillations in vitro. J Physiol (2004) 2.00
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress. J Neurochem (2006) 1.91
Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis. J Neurosci (2009) 1.85
A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats. Hippocampus (2008) 1.81
The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering. J Neurosci (2004) 1.75
Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy. Epilepsy Res (2009) 1.72
Orthogonal arrangement of rhythm-generating microcircuits in the hippocampus. Proc Natl Acad Sci U S A (2005) 1.71
Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity. Nat Neurosci (2003) 1.71
A revised nomenclature for the human and rodent alpha-tubulin gene family. Genomics (2007) 1.68
A heterozygous effect for PINK1 mutations in Parkinson's disease? Ann Neurol (2006) 1.61
Multiple origins of the cortical γ rhythm. Dev Neurobiol (2011) 1.61
Accelerated hippocampal spreading depression and enhanced locomotory activity in mice with astrocyte-directed inactivation of connexin43. J Neurosci (2003) 1.59
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes. Nat Genet (2013) 1.59
Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness. J Neurosci (2006) 1.58
Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? J Neurosci (2009) 1.57
Repetitive spreading depression-like events result in cell damage in juvenile hippocampal slice cultures maintained in normoxia. J Neurophysiol (2005) 1.52
Region-specific changes in gamma and beta2 rhythms in NMDA receptor dysfunction models of schizophrenia. Schizophr Bull (2008) 1.52
Mutations in the guanine nucleotide exchange factor gene IQSEC2 cause nonsyndromic intellectual disability. Nat Genet (2010) 1.52
Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease. Nat Genet (2006) 1.49
Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice. EMBO J (2007) 1.49
mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition. Neuron (2005) 1.47
The human cytomegalovirus UL44 protein is a substrate for the UL97 protein kinase. J Virol (2003) 1.42
A novel mechanism underlying drug resistance in chronic epilepsy. Ann Neurol (2003) 1.41
Complex role of collybistin and gephyrin in GABAA receptor clustering. J Biol Chem (2010) 1.40
TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins. Hum Mol Genet (2010) 1.35
GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy. Ann Neurol (2014) 1.34
Cell and gene therapies in epilepsy--promising avenues or blind alleys? Trends Neurosci (2008) 1.34
Pathophysiological mechanisms of dominant and recessive GLRA1 mutations in hyperekplexia. J Neurosci (2010) 1.33
A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation. Hum Mutat (2009) 1.32
The extracellular matrix molecule hyaluronic acid regulates hippocampal synaptic plasticity by modulating postsynaptic L-type Ca(2+) channels. Neuron (2010) 1.31
Endothelin-1 potently induces Leão's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura? Brain (2002) 1.30
Analog modulation of mossy fiber transmission is uncoupled from changes in presynaptic Ca2+. J Neurosci (2008) 1.28
Glycinergic transmission in the Mammalian retina. Front Mol Neurosci (2009) 1.24
Stimulus and potassium-induced epileptiform activity in the human dentate gyrus from patients with and without hippocampal sclerosis. J Neurosci (2004) 1.23
Subthreshold resonance explains the frequency-dependent integration of periodic as well as random stimuli in the entorhinal cortex. J Neurophysiol (2004) 1.22
Serotonin receptor 1A-modulated phosphorylation of glycine receptor α3 controls breathing in mice. J Clin Invest (2010) 1.21
Impaired hippocampal rhythmogenesis in a mouse model of mesial temporal lobe epilepsy. Proc Natl Acad Sci U S A (2007) 1.21
Gamma oscillations and spontaneous network activity in the hippocampus are highly sensitive to decreases in pO2 and concomitant changes in mitochondrial redox state. J Neurosci (2008) 1.19
Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of alpha 1 glycine receptors in HEK293 cells. J Neurosci Methods (2002) 1.19
Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy. J Cell Mol Med (2008) 1.18
Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia. J Biol Chem (2003) 1.17
Impact of aquaporin-4 channels on K+ buffering and gap junction coupling in the hippocampus. Glia (2011) 1.17
Cellular and network properties of the subiculum in the pilocarpine model of temporal lobe epilepsy. J Comp Neurol (2005) 1.17
Synaptic and vesicular coexistence of VGLUT and VGAT in selected excitatory and inhibitory synapses. J Neurosci (2010) 1.16
Episodic ataxia type 1 mutations differentially affect neuronal excitability and transmitter release. Dis Model Mech (2009) 1.16
Astrocytes as regulators of synaptic function: a quest for the Ca2+ master key. Neuroscientist (2011) 1.13
Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans. Brain (2005) 1.12
Interactions of 1263W94 with other antiviral agents in inhibition of human cytomegalovirus replication. Antimicrob Agents Chemother (2003) 1.11
Comment on "On the origin of interictal activity in human temporal lobe epilepsy in vitro". Science (2003) 1.10
Independent regulation of basal neurotransmitter release efficacy by variable Ca²+ influx and bouton size at small central synapses. PLoS Biol (2012) 1.10
NGF controls dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of Notch. Mol Biol Cell (2004) 1.08
Notch and NGF/p75NTR control dendrite morphology and the balance of excitatory/inhibitory synaptic input to hippocampal neurones through Neurogenin 3. J Neurochem (2006) 1.08
Presynaptic and postsynaptic mechanisms underlie paired pulse depression at single GABAergic boutons in rat collicular cultures. J Physiol (2002) 1.08
A 29-amino acid fragment of Clostridium botulinum C3 protein enhances neuronal outgrowth, connectivity, and reinnervation. FASEB J (2008) 1.08
Mitochondrial calcium ion and membrane potential transients follow the pattern of epileptiform discharges in hippocampal slice cultures. J Neurosci (2005) 1.07
Diversity of glycine receptors in the mouse retina: localization of the alpha4 subunit. J Comp Neurol (2007) 1.06
The range of intrinsic frequencies represented by medial entorhinal cortex stellate cells extends with age. J Neurosci (2010) 1.06
Changes in neural network homeostasis trigger neuropsychiatric symptoms. J Clin Invest (2014) 1.06
Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. Biochem Pharmacol (2008) 1.05
A gephyrin-related mechanism restraining glycine receptor anchoring at GABAergic synapses. J Neurosci (2004) 1.04
A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J Neurochem (2007) 1.04
Carbamazepine-resistance in the epileptic dentate gyrus of human hippocampal slices. Brain (2006) 1.03
Molecular determinants of glycine receptor alphabeta subunit sensitivities to Zn2+-mediated inhibition. J Physiol (2005) 1.02
Beta rhythms (15-20 Hz) generated by nonreciprocal communication in hippocampus. J Neurophysiol (2007) 1.02
The glycinergic system in human startle disease: a genetic screening approach. Front Mol Neurosci (2010) 1.02
Diversity of glycine receptors in the mouse retina: localization of the alpha3 subunit. J Comp Neurol (2003) 1.01
Free radical-mediated cell damage after experimental status epilepticus in hippocampal slice cultures. J Neurophysiol (2002) 1.01
Molecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrin. J Biol Chem (2011) 1.00
Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP). Eur J Neurosci (2007) 1.00
Effects of taurine and glycine on epileptiform activity induced by removal of Mg2+ in combined rat entorhinal cortex-hippocampal slices. Epilepsia (2003) 0.99
Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices. J Neurosci (2009) 0.98
The subiculum: a potential site of ictogenesis in human temporal lobe epilepsy. Epilepsia (2005) 0.97
Postsynaptic action of BDNF on GABAergic synaptic transmission in the superficial layers of the mouse superior colliculus. J Neurophysiol (2002) 0.97
Ion changes in spreading ischaemia induce rat middle cerebral artery constriction in the absence of NO. Brain (2005) 0.97
Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting. J Biol Chem (2009) 0.96
GABA(A) receptor activity and PKC control inhibitory synaptogenesis in CNS tissue slices. Mol Cell Neurosci (2003) 0.96
Diversity of glycine receptors in the mouse retina: localization of the alpha2 subunit. J Comp Neurol (2004) 0.96
Preferential accumulation of GABAA receptor gamma 2L, not gamma 2S, cytoplasmic loops at rat spinal cord inhibitory synapses. J Physiol (2004) 0.95
The cell adhesion molecule neurofascin stabilizes axo-axonic GABAergic terminals at the axon initial segment. J Biol Chem (2011) 0.95
Dopamine depresses cholinergic oscillatory network activity in rat hippocampus. Eur J Neurosci (2003) 0.94