Published in Am J Physiol Renal Physiol on May 17, 2005
Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol Rev (2008) 1.91
The role of endothelial cell injury in thrombotic microangiopathy. Am J Kidney Dis (2010) 1.10
Hypertensive crisis in children. Pediatr Nephrol (2011) 1.07
Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. Am J Med Sci (2010) 0.90
Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat. PLoS One (2012) 0.86
Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. J Biol Chem (2009) 0.85
Imatinib ameliorates renal morphological changes in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. Am J Physiol Renal Physiol (2011) 0.79
Renal functional responses to selective intrarenal renin inhibition in Cyp1a1-Ren2 transgenic rats with ANG II-dependent malignant hypertension. Am J Physiol Renal Physiol (2011) 0.79
Renal heme oxygenase-1 induction with hemin augments renal hemodynamics, renal autoregulation, and excretory function. Int J Hypertens (2012) 0.79
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. Am J Physiol Heart Circ Physiol (2009) 0.79
Transient induction of ANG II-dependent malignant hypertension causes sustained elevation of blood pressure and augmentation of the pressor response to ANG II in CYP1A1-REN2 transgenic rats. Am J Med Sci (2010) 0.77
Renal nitric oxide synthase and antioxidant preservation in Cyp1a1-Ren-2 transgenic rats with inducible malignant hypertension. Am J Hypertens (2013) 0.77
Salt-Sensitive Hypertension: Perspectives on Intrarenal Mechanisms. Curr Hypertens Rev (2015) 0.77
Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice. Diabetes (2004) 2.12
Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proc Natl Acad Sci U S A (2004) 2.08
Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. J Clin Invest (2003) 1.95
Dynamic analysis of stochastic transcription cycles. PLoS Biol (2011) 1.68
Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis. J Hypertens (2008) 1.61
alphaV integrins are necessary for eutrophic inward remodeling of small arteries in hypertension. Hypertension (2005) 1.59
A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice. Am J Physiol Renal Physiol (2012) 1.47
Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver. Hypertension (2009) 1.44
Dominant mutations of Col4a1 result in basement membrane defects which lead to anterior segment dysgenesis and glomerulopathy. Hum Mol Genet (2005) 1.33
Genetic clamping of renin gene expression induces hypertension and elevation of intrarenal Ang II levels of graded severity in Cyp1a1-Ren2 transgenic rats. J Renin Angiotensin Aldosterone Syst (2006) 1.29
Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes. J Immunol (2006) 1.27
Optimal elevation of β-cell 11β-hydroxysteroid dehydrogenase type 1 is a compensatory mechanism that prevents high-fat diet-induced β-cell failure. Diabetes (2012) 1.22
Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling. Endocrinology (2005) 1.20
The mother or the fetus? 11beta-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids. J Neurosci (2006) 1.16
Systolic and diastolic ventricular function in zebrafish embryos: influence of norepenephrine, MS-222 and temperature. BMC Biotechnol (2008) 1.15
Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice. J Neurosci (2007) 1.14
Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. Am J Physiol Renal Physiol (2007) 1.13
Enhancement of renin and prorenin receptor in collecting duct of Cyp1a1-Ren2 rats may contribute to development and progression of malignant hypertension. Am J Physiol Renal Physiol (2010) 1.11
Proximal tubular fluid angiotensin II levels in angiotensin II-induced hypertensive rats. J Hypertens (2003) 1.10
Hypertension, kidney, and transgenics: a fresh perspective. Physiol Rev (2006) 1.10
Functional significance of prorenin internalization in the rat heart. Circ Res (2002) 1.08
AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension. J Hypertens (2006) 1.07
Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome. Hypertension (2009) 1.06
11beta-hydroxysteroid dehydrogenase type 2 in mouse aorta: localization and influence on response to glucocorticoids. Hypertension (2003) 1.04
Dynamic organisation of prolactin gene expression in living pituitary tissue. J Cell Sci (2010) 1.03
Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model. Mol Endocrinol (2009) 1.03
11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments. J Neurosci (2010) 1.01
Efficient gene targeting by homologous recombination in rat embryonic stem cells. PLoS One (2010) 1.01
Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats. Am J Physiol Renal Physiol (2007) 1.01
A switch in the mechanism of hypertension in the syndrome of apparent mineralocorticoid excess. J Am Soc Nephrol (2007) 1.01
Insights from the rat genome sequence. Genome Biol (2004) 1.00
Acute inhibition of NCC does not activate distal electrogenic Na+ reabsorption or kaliuresis. Am J Physiol Renal Physiol (2014) 0.99
Enhanced tubuloglomerular feedback in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. Am J Physiol Renal Physiol (2005) 0.98
Cyclooxygenase-2 inhibition normalizes arterial blood pressure in CYP1A1-REN2 transgenic rats with inducible ANG II-dependent malignant hypertension. Am J Physiol Renal Physiol (2006) 0.97
AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet. Am J Med Sci (2010) 0.94
Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume. Hum Mol Genet (2010) 0.94
Mice deficient in 11beta-hydroxysteroid dehydrogenase type 1 lack bone marrow adipocytes, but maintain normal bone formation. Endocrinology (2004) 0.94
Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension. Am J Physiol Renal Physiol (2007) 0.94
Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae. J Physiol (2012) 0.94
Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice. Endocrinology (2006) 0.93
Salt-sensitive hypertension develops after transient induction of ANG II-dependent hypertension in Cyp1a1-Ren2 transgenic rats. Am J Physiol Renal Physiol (2004) 0.92
Class III antiarrhythmic methanesulfonanilides inhibit leukocyte recruitment in zebrafish. J Leukoc Biol (2007) 0.92
11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: A novel constraint to hyperphagia? Endocrinology (2006) 0.92
Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. Am J Med Sci (2010) 0.90
Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy. J Am Soc Nephrol (2011) 0.90
Failure to downregulate the epithelial sodium channel causes salt sensitivity in Hsd11b2 heterozygote mice. Hypertension (2012) 0.89
Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats. J Hypertens (2010) 0.89
11 Beta-hydroxysteroid dehydrogenases in the brain: two enzymes two roles. Ann N Y Acad Sci (2003) 0.89
Derivation, characterization, and stable transfection of induced pluripotent stem cells from Fischer344 rats. PLoS One (2011) 0.87
Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat. PLoS One (2012) 0.86
Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats. J Hypertens (2009) 0.86
A novel transmembrane MSP-containing protein that plays a role in right ventricle development. Genomics (2004) 0.86
Renal pericytes: multifunctional cells of the kidneys. Pflugers Arch (2013) 0.86
Nuclear transfer in rodents. J Physiol (2004) 0.86
Laser-targeted ablation of the zebrafish embryonic ventricle: a novel model of cardiac injury and repair. Int J Cardiol (2013) 0.86
Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. J Biol Chem (2009) 0.85
Direct renin inhibition with aliskiren normalizes blood pressure in Cyp1a1-Ren2 transgenic rats with inducible angiotensin ii-dependent malignant hypertension. Am J Med Sci (2011) 0.84
Transgenesis in the rat. Methods Mol Biol (2002) 0.84
Rat eggs cannot wait: Spontaneous exit from meiotic metaphase-II arrest. Mol Reprod Dev (2011) 0.82
Pulsatile patterns of pituitary hormone gene expression change during development. J Cell Sci (2011) 0.82
Genetic manipulation of 11beta-hydroxysteroid dehydrogenases in mice. Am J Physiol Regul Integr Comp Physiol (2005) 0.81
Cyp11b1 null mouse, a model of congenital adrenal hyperplasia. J Biol Chem (2008) 0.80
Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney. Physiol Genomics (2009) 0.80
The complex interplay between cyclooxygenase-2 and angiotensin II in regulating kidney function. Curr Opin Nephrol Hypertens (2012) 0.80
Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats. Front Physiol (2013) 0.79
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. Am J Physiol Heart Circ Physiol (2009) 0.79
Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model. Endocrinology (2012) 0.79
Chronic direct renin inhibition with aliskiren prevents the development of hypertension in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent hypertension. Am J Med Sci (2012) 0.79
The role of the renin-angiotensin system in malignant vascular injury affecting the systemic and cerebral circulations. Prog Biophys Mol Biol (2004) 0.79
Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats. J Renin Angiotensin Aldosterone Syst (2013) 0.79
The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats. J Cell Mol Med (2009) 0.79
Renal functional responses to selective intrarenal renin inhibition in Cyp1a1-Ren2 transgenic rats with ANG II-dependent malignant hypertension. Am J Physiol Renal Physiol (2011) 0.79
Use of fiber optic technology to measure the effects of anesthesia on luciferase reaction kinetics. J Am Assoc Lab Anim Sci (2012) 0.79
Imatinib ameliorates renal morphological changes in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. Am J Physiol Renal Physiol (2011) 0.79
Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis. Nephrology (Carlton) (2014) 0.78
Transient renin-angiotensin system stimulation in an early stage of life causes sustained hypertension in rats. J Hypertens (2011) 0.78
Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response. PLoS One (2013) 0.78
Renal nitric oxide synthase and antioxidant preservation in Cyp1a1-Ren-2 transgenic rats with inducible malignant hypertension. Am J Hypertens (2013) 0.77
Large transgenes reveal their secrets. Focus on "differential expression of the closely linked KISS1, REN, and FLJ10761 genes in transgenic mice". Physiol Genomics (2004) 0.77
Transient induction of ANG II-dependent malignant hypertension causes sustained elevation of blood pressure and augmentation of the pressor response to ANG II in CYP1A1-REN2 transgenic rats. Am J Med Sci (2010) 0.77
An anatomically unbiased approach for analysis of renal BOLD magnetic resonance images. Am J Physiol Renal Physiol (2013) 0.77
Transition from organogenesis to stem cell maintenance in the mouse adrenal cortex. Organogenesis (2011) 0.77
Renoprotective effects of direct renin inhibition in glomerulonephritis. Am J Med Sci (2014) 0.76
Regression of cardiac hypertrophy in cyp1a1ren-2 transgenic rats. J Magn Reson Imaging (2012) 0.76
In silico structure-function analysis of pathological variation in the HSD11B2 gene sequence. Physiol Genomics (2010) 0.76
Role of endothelin receptors for renal protection and survival in hypertension: waiting for clinical trials. Hypertension (2006) 0.75
Targeted laser ablation of the zebrafish larval heart induces models of heart block, valvular regurgitation, and outflow tract obstruction. Zebrafish (2014) 0.75