| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.
|
Neuroimage
|
2009
|
1.42
|
|
2
|
The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.
|
Neuropsychopharmacology
|
2007
|
1.34
|
|
3
|
Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.
|
J Nucl Med
|
2009
|
1.31
|
|
4
|
Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.
|
J Med Chem
|
2008
|
1.30
|
|
5
|
The role of 5-HT(1A) receptors in control of lower urinary tract function in cats.
|
Brain Res
|
2002
|
1.26
|
|
6
|
Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents.
|
Neuroimage
|
2008
|
0.99
|
|
7
|
Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors.
|
Cell Mol Neurobiol
|
2006
|
0.93
|
|
8
|
Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography.
|
Eur J Nucl Med Mol Imaging
|
2010
|
0.92
|
|
9
|
[3H]LY334370, a novel radioligand for the 5-HT1F receptor. II. Autoradiographic localization in rat, guinea pig, monkey and human brain.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2005
|
0.83
|
|
10
|
Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.
|
Int J Neuropsychopharmacol
|
2010
|
0.82
|
|
11
|
Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists.
|
Bioorg Med Chem Lett
|
2004
|
0.82
|
|
12
|
Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: a potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine.
|
J Pharmacol Exp Ther
|
2005
|
0.82
|
|
13
|
[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2005
|
0.78
|
|
14
|
Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides.
|
J Med Chem
|
2003
|
0.75
|
|
15
|
Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.
|
Bioorg Med Chem Lett
|
2007
|
0.75
|
|
16
|
Pharmacological characterization of the cannabinoid CB₁ receptor PET ligand ortholog, [³H]MePPEP.
|
Eur J Pharmacol
|
2010
|
0.75
|
|
17
|
Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists.
|
Bioorg Med Chem Lett
|
2004
|
0.75
|