Endothelin receptor B is required for the expansion of melanocyte precursors and malignant melanoma.

Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Mol Cancer Res (2008) 1.99

The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house? Br J Pharmacol (2007) 1.38

Role of the endothelin axis and its antagonists in the treatment of cancer. Br J Pharmacol (2011) 1.21

Malignant melanoma in the 21st century: the emerging molecular landscape. Mayo Clin Proc (2008) 1.13

The role of positive selection in determining the molecular cause of species differences in disease. BMC Evol Biol (2008) 1.11

Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer. Neoplasia (2011) 1.09

Endothelin B receptor, a new target in cancer immune therapy. Clin Cancer Res (2009) 1.05

Melanocyte receptors: clinical implications and therapeutic relevance. Dermatol Clin (2007) 1.01

Form-deprivation myopia in chick induces limited changes in retinal gene expression. Invest Ophthalmol Vis Sci (2007) 1.00

Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells. PLoS One (2010) 0.98

G-protein-coupled receptors and melanoma. Pigment Cell Melanoma Res (2008) 0.97

Biomarkers: the useful and the not so useful--an assessment of molecular prognostic markers for cutaneous melanoma. J Invest Dermatol (2010) 0.95

Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ET(B) receptor-mediated G(i)- and G(q)-pathways and MAP kinase activation. Br J Pharmacol (2008) 0.89

Long-lasting molecular changes in human skin after repetitive in situ UV irradiation. J Invest Dermatol (2008) 0.87

Microenvironment-derived factors driving metastatic plasticity in melanoma. Nat Commun (2017) 0.81

Zebrafish endzone regulates neural crest-derived chromatophore differentiation and morphology. PLoS One (2008) 0.75

Rendomab B4, a monoclonal antibody that discriminates the human endothelin B receptor of melanoma cells and inhibits their migration. MAbs (2016) 0.75

Substance P stimulates endothelin 1 secretion via endothelin-converting enzyme 1 and promotes melanogenesis in human melanocytes. J Invest Dermatol (2014) 0.75

Endothelin-1 (ET-1) induces resistance to bortezomib in human multiple myeloma cells via a pathway involving the ETB receptor and upregulation of proteasomal activity. J Cancer Res Clin Oncol (2016) 0.75