Published in Nat Struct Mol Biol on May 22, 2005
Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone. Proc Natl Acad Sci U S A (2005) 2.73
The mineralocorticoid receptor: insights into its molecular and (patho)physiological biology. Nucl Recept Signal (2007) 1.89
Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annu Rev Physiol (2010) 1.68
A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule. J Biol Chem (2010) 1.07
Intensity statistics in the presence of translational noncrystallographic symmetry. Acta Crystallogr D Biol Crystallogr (2013) 1.01
Structural and functional insights into nuclear receptor signaling. Adv Drug Deliv Rev (2010) 0.89
Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors. BMC Evol Biol (2007) 0.86
Purification and characterization of recombinant human mineralocorticoid receptor. Mol Cell Endocrinol (2008) 0.83
Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators. J Biol Chem (2011) 0.81
Association of aldosterone and cortisol with cardiovascular risk factors in prehypertension stage. Int J Hypertens (2012) 0.79
Helix 3-helix 5 interactions in steroid hormone receptor function. J Steroid Biochem Mol Biol (2008) 0.78
X-ray structures of progesterone receptor ligand binding domain in its agonist state reveal differing mechanisms for mixed profiles of 11β-substituted steroids. J Biol Chem (2012) 0.77
Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1. J Biol Chem (2015) 0.77
3D model of lamprey estrogen receptor with estradiol and 15alpha-hydroxy-estradiol. PLoS One (2009) 0.76
Predicting the relative binding affinity of mineralocorticoid receptor antagonists by density functional methods. J Comput Aided Mol Des (2015) 0.75
A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system. J Antimicrob Chemother (2012) 2.16
Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria. FEMS Microbiol Rev (2008) 1.77
Crystal structure of a novel beta-lactam-insensitive peptidoglycan transpeptidase. J Mol Biol (2006) 1.76
11beta-hydroxysteroid dehydrogenase types 1 and 2: an important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids. J Clin Endocrinol Metab (2002) 1.68
Aldosterone activates NF-kappaB in the collecting duct. J Am Soc Nephrol (2008) 1.67
Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France. Antimicrob Agents Chemother (2008) 1.63
Crystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukarya. J Biol Chem (2002) 1.52
Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. J Biol Chem (2007) 1.46
Functional analysis of DNA gyrase mutant enzymes carrying mutations at position 88 in the A subunit found in clinical strains of Mycobacterium tuberculosis resistant to fluoroquinolones. Antimicrob Agents Chemother (2006) 1.42
Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. PLoS One (2010) 1.35
Specificity of L,D-transpeptidases from gram-positive bacteria producing different peptidoglycan chemotypes. J Biol Chem (2007) 1.34
An unusual primary sigma factor in the Bacteroidetes phylum. Mol Microbiol (2005) 1.23
Crystal structures of Weissella viridescens FemX and its complex with UDP-MurNAc-pentapeptide: insights into FemABX family substrates recognition. Structure (2004) 1.19
Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties. Eur J Endocrinol (2004) 1.16
Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis. Antimicrob Agents Chemother (2012) 1.09
A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule. J Biol Chem (2010) 1.07
Expression and molecular characterization of alternative transcripts of the ARHGEF5/TIM oncogene specific for human breast cancer. Hum Mol Genet (2003) 1.03
DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother (2011) 1.02
Idiosyncratic features in tRNAs participating in bacterial cell wall synthesis. Nucleic Acids Res (2007) 0.99
Structure-based site-directed mutagenesis of the UDP-MurNAc-pentapeptide-binding cavity of the FemX alanyl transferase from Weissella viridescens. J Bacteriol (2005) 0.96
Steroid profiling in preeclamptic women: evidence for aromatase deficiency. Am J Obstet Gynecol (2010) 0.94
Purification, crystallization and preliminary X-ray diffraction experiments on the breakage-reunion domain of the DNA gyrase from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.91
Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion. Biochem J (2013) 0.86
Mutagenesis in the alpha3alpha4 GyrA helix and in the Toprim domain of GyrB refines the contribution of Mycobacterium tuberculosis DNA gyrase to intrinsic resistance to quinolones. Antimicrob Agents Chemother (2008) 0.86
Mineralocorticoid receptor mutations and a severe recessive pseudohypoaldosteronism type 1. J Am Soc Nephrol (2011) 0.85
Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol Pharmacol (2007) 0.83
Met909 plays a key role in the activation of the progesterone receptor and also in the high potency of 13-ethyl progestins. Mol Pharmacol (2009) 0.83
Crl binds to domain 2 of σ(S) and confers a competitive advantage on a natural rpoS mutant of Salmonella enterica serovar Typhi. J Bacteriol (2010) 0.83
Structure of the archaeal pab87 peptidase reveals a novel self-compartmentalizing protease family. PLoS One (2009) 0.83
The structure of FemX(Wv) in complex with a peptidyl-RNA conjugate: mechanism of aminoacyl transfer from Ala-tRNA(Ala) to peptidoglycan precursors. Angew Chem Int Ed Engl (2013) 0.82
Circulating cell-free DNA in plasma of locally advanced rectal cancer patients undergoing preoperative chemoradiation: a potential diagnostic tool for therapy monitoring. Dis Markers (2008) 0.81
The Met852 residue is a key organizer of the ligand-binding cavity of the human mineralocorticoid receptor. Mol Pharmacol (2005) 0.81
Conditional gene expression in renal collecting duct epithelial cells: use of the inducible Cre-lox system. Am J Physiol Renal Physiol (2003) 0.81
Conformational transition of DNA bound to Hfq probed by infrared spectroscopy. Phys Chem Chem Phys (2010) 0.80
Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension. Mol Cell Endocrinol (2004) 0.80
Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes. Biochem J (2013) 0.80
Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1. J Clin Endocrinol Metab (2010) 0.79
Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase CTD. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.79
Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor. J Steroid Biochem Mol Biol (2004) 0.79
The Molecular Genetics of Fluoroquinolone Resistance in Mycobacterium tuberculosis. Microbiol Spectr (2014) 0.79
The synthetic androgen methyltrienolone (r1881) acts as a potent antagonist of the mineralocorticoid receptor. Mol Pharmacol (2006) 0.78
A structural explanation of the effects of dissociated glucocorticoids on glucocorticoid receptor transactivation. Mol Pharmacol (2013) 0.77
Cloning, purification, crystallization and preliminary crystallographic analysis of a hypothetical acetyltransferase from Pyrococcus furiosus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.77
Cloning, purification, crystallization and preliminary crystallographic analysis of a penicillin-binding protein homologue from Pyrococcus abyssi. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.77
Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/σS subunit of RNA polymerase. Biochem J (2014) 0.77
Glucocorticoid metabolism by 11-beta hydroxysteroid dehydrogenase type 2 modulates human mineralocorticoid receptor transactivation activity. J Steroid Biochem Mol Biol (2003) 0.77
Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase ATPase domain. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.77
A new strategy for selective targeting of progesterone receptor with passive antagonists. Mol Endocrinol (2013) 0.77
Thermodynamics of the beta(2) association in light-harvesting complex I of Rhodospirillum rubrum. Implication of peptide identity in dimer stability. FEBS J (2008) 0.75
Probing the importance of selected phylum-specific amino acids in sigma A of Bacteroides fragilis, a primary sigma factor naturally devoid of an N-terminal acidic region 1.1. J Biol Chem (2006) 0.75
Crystallization and preliminary X-ray analysis of Weissella viridescens FemX UDP-MurNAc-pentapeptide:l-alanine ligase. Acta Crystallogr D Biol Crystallogr (2003) 0.75
Structural determinants of ligand binding to the mineralocorticoid receptor. Mol Cell Endocrinol (2011) 0.75