Published in J Inorg Biochem on June 01, 2005
Structural comparison of human mammalian ste20-like kinases. PLoS One (2010) 1.00
Understanding the role of PknJ in Mycobacterium tuberculosis: biochemical characterization and identification of novel substrate pyruvate kinase A. PLoS One (2010) 0.93
A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3). Biochem J (2012) 0.87
The dual enzyme LRRK2 hydrolyzes GTP in both its GTPase and kinase domains in vitro. Biochim Biophys Acta (2016) 0.75
MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer. Oncotarget (2016) 0.75
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science (2008) 2.96
Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. BMC Genomics (2007) 2.32
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Proc Natl Acad Sci U S A (2007) 2.00
Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase. J Biol Chem (2004) 1.86
Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage. Carcinogenesis (2004) 1.67
Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression. Nucleic Acids Res (2008) 1.66
Identification of calcineurin as a key signal in the extinction of fear memory. J Neurosci (2003) 1.64
POINT: a database for the prediction of protein-protein interactions based on the orthologous interactome. Bioinformatics (2004) 1.58
A stochastic differential equation model for quantifying transcriptional regulatory network in Saccharomyces cerevisiae. Bioinformatics (2005) 1.56
Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A. Mol Cell Biol (2005) 1.54
Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. J Biol Chem (2011) 1.52
PhosphoPOINT: a comprehensive human kinase interactome and phospho-protein database. Bioinformatics (2008) 1.47
Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J Immunol (2003) 1.41
Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening. J Biol Chem (2005) 1.40
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region. J Biol Chem (2004) 1.38
Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma. Oncogene (2003) 1.36
Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology (2005) 1.35
Biosignaling of mammalian Ste20-related kinases. Cell Signal (2008) 1.34
Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription. Mol Cell Biol (2006) 1.32
Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis. Mol Biol Cell (2008) 1.31
Prognostic significance of prostate cancer susceptibility variants on prostate-specific antigen recurrence after radical prostatectomy. Cancer Epidemiol Biomarkers Prev (2009) 1.31
VEGFA upregulates FLJ10540 and modulates migration and invasion of lung cancer via PI3K/AKT pathway. PLoS One (2009) 1.28
Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process. J Mol Biol (2008) 1.26
Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-kappaB-induced CCAAT/enhancer-binding protein delta in mouse macrophages. Cell Signal (2006) 1.24
A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells. J Biol Chem (2008) 1.22
Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex. J Biol Chem (2008) 1.21
Neutrophils and macrophages promote angiogenesis in the early stage of endometriosis in a mouse model. Endocrinology (2005) 1.20
Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells. Int J Cancer (2009) 1.19
Nuclear export and import of human hepatitis B virus capsid protein and particles. PLoS Pathog (2010) 1.18
Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis. J Biol Chem (2004) 1.15
Individual and cumulative association of prostate cancer susceptibility variants with clinicopathologic characteristics of the disease. Clin Chim Acta (2010) 1.13
Polymorphisms inside microRNAs and microRNA target sites predict clinical outcomes in prostate cancer patients receiving androgen-deprivation therapy. Clin Cancer Res (2010) 1.13
Ortholog-based protein-protein interaction prediction and its application to inter-species interactions. BMC Bioinformatics (2008) 1.12
Collapsin response mediator protein-1: a novel invasion-suppressor gene. Clin Exp Metastasis (2003) 1.12
Mechanism of action and inhibition of dehydrosqualene synthase. Proc Natl Acad Sci U S A (2010) 1.11
Src oncogene activates MMP-2 expression via the ERK/Sp1 pathway. J Cell Physiol (2006) 1.10
Induction of disease-associated keratin 16 gene expression by epidermal growth factor is regulated through cooperation of transcription factors Sp1 and c-Jun. J Biol Chem (2003) 1.09
Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells. Cell Signal (2011) 1.09
Functional role of NF-IL6beta and its sumoylation and acetylation modifications in promoter activation of cyclooxygenase 2 gene. Nucleic Acids Res (2006) 1.08
Therapeutic HER2/Neu DNA vaccine inhibits mouse tumor naturally overexpressing endogenous neu. Mol Ther (2004) 1.08
RNA-binding protein HuR interacts with thrombomodulin 5'untranslated region and represses internal ribosome entry site-mediated translation under IL-1 beta treatment. Mol Biol Cell (2008) 1.07
Sp1-mediated microRNA-182 expression regulates lung cancer progression. Oncotarget (2014) 1.07
Combination of microarray profiling and protein-protein interaction databases delineates the minimal discriminators as a metastasis network for esophageal squamous cell carcinoma. Int J Oncol (2009) 1.07
The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis. Biomaterials (2011) 1.06
Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase. J Biol Chem (2007) 1.06
Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis. J Biol Chem (2002) 1.05
Maturation processing and characterization of streptopain. J Biol Chem (2003) 1.04
ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression. J Biol Chem (2007) 1.04
Endoplasmic reticulum stress stimulates p53 expression through NF-κB activation. PLoS One (2012) 1.04
Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo. BMC Dev Biol (2007) 1.02
Interplay of posttranslational modifications in Sp1 mediates Sp1 stability during cell cycle progression. J Mol Biol (2011) 1.01
Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST. J Biol Chem (2006) 1.01
Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model. Mol Cell Proteomics (2003) 1.01
Redox-sensitive endoplasmic reticulum stress and autophagy at rostral ventrolateral medulla contribute to hypertension in spontaneously hypertensive rats. Hypertension (2013) 1.01
Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells. PLoS One (2011) 1.00
Clinical significance of runt-related transcription factor 1 polymorphism in prostate cancer. BJU Int (2010) 1.00
A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA. Clin Cancer Res (2009) 1.00
ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer. Cancer Res (2009) 0.99
Distinct regulation of cyclooxygenase-2 by interleukin-1beta in normal and endometriotic stromal cells. J Clin Endocrinol Metab (2004) 0.98
Loss of E-cadherin and beta-catenin is correlated with poor prognosis of ampullary neoplasms. J Surg Oncol (2010) 0.98
Heat shock protein 72 is associated with the hepatitis C virus replicase complex and enhances viral RNA replication. J Biol Chem (2010) 0.98
Gene expression profiles of the aurora family kinases. Gene Expr (2006) 0.97
Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway. Chem Res Toxicol (2010) 0.97
HDAC1/HDAC3 modulates PPARG2 transcription through the sumoylated CEBPD in hepatic lipogenesis. Biochim Biophys Acta (2008) 0.97
Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover. Mol Biol Cell (2007) 0.97
Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (Encyclopedia of Hepatocellular Carcinoma genes Online). BMC Bioinformatics (2007) 0.97
Aberrant cyclin A expression and centrosome overduplication induced by hepatitis B virus pre-S2 mutants and its implication in hepatocarcinogenesis. Carcinogenesis (2011) 0.96
Hepatitis B virus pre-S2 mutant surface antigen induces degradation of cyclin-dependent kinase inhibitor p27Kip1 through c-Jun activation domain-binding protein 1. Mol Cancer Res (2007) 0.96
Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis. Proc Natl Acad Sci U S A (2010) 0.96
Selective inhibition of early--but not late--expressed HIF-1α is neuroprotective in rats after focal ischemic brain damage. Brain Pathol (2010) 0.96
Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma. Oncotarget (2014) 0.95
A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells. Carcinogenesis (2013) 0.95
Opposing effects of beta-arrestin1 and beta-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1. Cell Signal (2006) 0.95
Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein. J Proteome Res (2011) 0.95
Butyrate reduced lipopolysaccharide-mediated macrophage migration by suppression of Src enhancement and focal adhesion kinase activity. J Nutr Biochem (2010) 0.95
Rubrobacter taiwanensis sp. nov., a novel thermophilic, radiation-resistant species isolated from hot springs. Int J Syst Evol Microbiol (2004) 0.95
Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway. J Agric Food Chem (2011) 0.95
Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin. J Biol Chem (2007) 0.94
Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules. Mol Carcinog (2010) 0.94
Heat shock protein 90 is important for Sp1 stability during mitosis. J Mol Biol (2009) 0.93
Eps8 decreases chemosensitivity and affects survival of cervical cancer patients. Mol Cancer Ther (2008) 0.93
Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells. Nucleic Acids Res (2007) 0.93
Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer. Am J Respir Crit Care Med (2012) 0.93
From midbody protein-protein interaction network construction to novel regulators in cytokinesis. J Proteome Res (2009) 0.92
ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells. J Cell Biochem (2011) 0.92
Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma. PLoS One (2011) 0.92
Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions. J Clin Invest (2012) 0.92