Jon B Klein

Author PubWeight™ 114.62‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 2009 11.81
2 Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. Diabetes 2009 3.16
3 Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. Free Radic Biol Med 2005 2.51
4 Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radic Biol Med 2002 2.10
5 Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease. Neurobiol Dis 2006 2.04
6 Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes. Am J Physiol Endocrinol Metab 2004 2.03
7 Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils. J Am Soc Nephrol 2002 1.92
8 Heat shock protein 27 controls apoptosis by regulating Akt activation. J Biol Chem 2003 1.90
9 Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71. J Neurochem 2002 1.73
10 Proteomic identification of nitrated proteins in Alzheimer's disease brain. J Neurochem 2003 1.70
11 Differential expression of proteins in renal cortex and medulla: a proteomic approach. Kidney Int 2002 1.61
12 Recommendations for biomarker identification and qualification in clinical proteomics. Sci Transl Med 2010 1.59
13 Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Neurobiol Dis 2005 1.58
14 Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria. J Am Soc Nephrol 2009 1.57
15 Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation. Kidney Int 2002 1.56
16 Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding. Mol Cell Biol 2003 1.53
17 Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD. Neurobiol Aging 2005 1.52
18 Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome. Kidney Int 2010 1.52
19 Akt phosphorylates p47phox and mediates respiratory burst activity in human neutrophils. J Immunol 2003 1.50
20 Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis. Neurobiol Aging 2005 1.50
21 AGRO100 inhibits activation of nuclear factor-kappaB (NF-kappaB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin. Mol Cancer Ther 2006 1.44
22 Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease. Neurobiol Dis 2008 1.38
23 Proteomics analysis of the Alzheimer's disease hippocampal proteome. J Alzheimers Dis 2007 1.32
24 Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury. J Neurotrauma 2007 1.30
25 Proteomic analysis of protein expression and oxidative modification in r6/2 transgenic mice: a model of Huntington disease. Mol Cell Proteomics 2005 1.25
26 An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach. J Neurosci Res 2007 1.23
27 Splice variants of neuronal nitric oxide synthase are present in the rat kidney. Nephrol Dial Transplant 2008 1.21
28 Microfiltration isolation of human urinary exosomes for characterization by MS. Proteomics Clin Appl 2009 1.19
29 Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy. Am J Physiol Renal Physiol 2009 1.19
30 Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease. Neurobiol Aging 2006 1.17
31 Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice. Am J Physiol Renal Physiol 2007 1.11
32 Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis. Neurobiol Aging 2005 1.10
33 Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells. Infect Immun 2002 1.10
34 Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-beta receptor/phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells. FASEB J 2003 1.09
35 Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Abeta(1-42): implications for Alzheimer's disease. Neurobiol Aging 2005 1.09
36 Effects of ACE inhibition on proximal tubule sodium transport. Am J Physiol Renal Physiol 2005 1.09
37 Prediction of delayed renal allograft function using an artificial neural network. Nephrol Dial Transplant 2003 1.07
38 Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease. Brain Res 2005 1.06
39 Urinary proteomics and biomarker discovery for glomerular diseases. Contrib Nephrol 2004 1.06
40 Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis. J Am Soc Nephrol 2004 1.05
41 Identification of the p16-Arc subunit of the Arp 2/3 complex as a substrate of MAPK-activated protein kinase 2 by proteomic analysis. J Biol Chem 2003 1.04
42 Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. Free Radic Biol Med 2005 1.03
43 Proteomic analysis of renal calculi indicates an important role for inflammatory processes in calcium stone formation. Am J Physiol Renal Physiol 2008 0.99
44 Synthesis and secretion of hemoglobin by retinal pigment epithelium. Invest Ophthalmol Vis Sci 2008 0.99
45 Sample preparation for 2-D proteomic analysis. Contrib Nephrol 2004 0.96
46 Fluoride exposure attenuates expression of Streptococcus pyogenes virulence factors. J Biol Chem 2002 0.96
47 Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension. J Biol Chem 2002 0.96
48 Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein. Brain Res Mol Brain Res 2005 0.96
49 Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: an initial assessment. J Alzheimers Dis 2006 0.95
50 Proteomic analysis of CA1 and CA3 regions of rat hippocampus and differential susceptibility to intermittent hypoxia. J Neurochem 2002 0.95
51 Urinary protein expression patterns in children with sleep-disordered breathing: preliminary findings. Sleep Med 2006 0.94
52 Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates. J Biol Chem 2013 0.93
53 Gamma-amino butyric acid type B receptors stimulate neutrophil chemotaxis during ischemia-reperfusion. J Immunol 2005 0.92
54 Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling. Biochim Biophys Acta 2009 0.92
55 Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders. Neurochem Int 2005 0.91
56 Molecular conformation dictates signaling module formation: example of PKCepsilon and Src tyrosine kinase. Am J Physiol Heart Circ Physiol 2002 0.91
57 Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat. Brain Res Mol Brain Res 2005 0.90
58 Proteomics analysis of human astrocytes expressing the HIV protein Tat. Brain Res Mol Brain Res 2005 0.90
59 Plasma kininogen and kininogen fragments are biomarkers of progressive renal decline in type 1 diabetes. Kidney Int 2013 0.90
60 Renal tubulointerstitial fibrosis in OVE26 type 1 diabetic mice. Nephron Exp Nephrol 2008 0.89
61 Proteomic identification of a large complement of rat urinary proteins. Nephron Exp Nephrol 2003 0.89
62 Calorimetric analysis of the plasma proteome: identification of type 1 diabetes patients with early renal function decline. Biochim Biophys Acta 2013 0.88
63 Proteomics and diabetic nephropathy. Semin Nephrol 2007 0.88
64 A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells. J Proteome Res 2006 0.87
65 Regulation of neutrophil apoptosis by modulation of PKB/Akt activation. Front Biosci (Landmark Ed) 2009 0.86
66 Oxidative stress in the aging murine olfactory bulb: redox proteomics and cellular localization. J Neurosci Res 2007 0.86
67 Redox proteomic identification of oxidized cardiac proteins in adriamycin-treated mice. Free Radic Biol Med 2006 0.86
68 Proteomic techniques identify urine proteins that differentiate patients with interstitial cystitis from asymptomatic control subjects. Am J Obstet Gynecol 2008 0.85
69 Proteomics and diabetic retinopathy. Clin Lab Med 2009 0.84
70 Protective effect of D609 against amyloid-beta1-42-induced oxidative modification of neuronal proteins: redox proteomics study. J Neurosci Res 2006 0.84
71 Analysis of expression and posttranslational modification of proteins during hypoxia. J Appl Physiol (1985) 2004 0.84
72 Gamma-glutamylcysteine ethyl ester protection of proteins from Abeta(1-42)-mediated oxidative stress in neuronal cell culture: a proteomics approach. J Neurosci Res 2005 0.83
73 Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: implications for low vitamin D-dependent age-related cognitive decline. Free Radic Biol Med 2013 0.83
74 Modulation of cytochrome C oxidase-va is possibly involved in metallothionein protection from doxorubicin cardiotoxicity. J Pharmacol Exp Ther 2005 0.83
75 Proteomic discovery of diabetic nephropathy biomarkers. Adv Chronic Kidney Dis 2010 0.82
76 Proteomic identification and immunolocalization of increased renal calbindin-D28k expression in OVE26 diabetic mice. Rev Diabet Stud 2005 0.81
77 Elongin C is a mediator of Notch4 activity in human renal tubule cells. Biochim Biophys Acta 2011 0.80
78 Sodium loading changes urinary protein excretion: a proteomic analysis. Am J Physiol Renal Physiol 2003 0.80
79 Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study. Free Radic Biol Med 2013 0.80
80 Proteomic analysis of human neutrophils. Methods Mol Biol 2006 0.80
81 Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporter. Cell Physiol Biochem 2011 0.79
82 Proteomics and diabetic nephropathy. Contrib Nephrol 2004 0.79
83 Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53. PLoS One 2012 0.79
84 Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease. J Neurochem 2015 0.78
85 Lymphocyte mitochondria: toward identification of peripheral biomarkers in the progression of Alzheimer disease. Free Radic Biol Med 2013 0.78
86 Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice. Cell Stress Chaperones 2016 0.77
87 Technical note: proteomic approaches to fundamental questions about neutrophil biology. J Leukoc Biol 2013 0.77
88 Proteomics in CKD. Adv Chronic Kidney Dis 2010 0.77
89 Two-dimensional gel electrophoresis: a fundamental tool for expression proteomics studies. Contrib Nephrol 2004 0.76
90 Utlization of human expert techniques for detection of low-abundant peaks in high-resolution mass spectra. Conf Proc IEEE Eng Med Biol Soc 2006 0.76
91 Proteomics and hypertension. Contrib Nephrol 2004 0.76
92 New treatments for CKD--new insights into pathogenesis. J Am Soc Nephrol 2012 0.75
93 Proteomics and diabetic nephropathy. Curr Diab Rep 2005 0.75
94 Ich denk' es war ein gutes Jahr* (Reinhard Mey, 1968)--the year 2010 balance. Int J Artif Organs 2010 0.75
95 Practical bioinformatics for proteomics. Contrib Nephrol 2004 0.75
96 It's the end of the world as we know it* - an era comes to a close. Int J Artif Organs 2009 0.75