| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.
|
Immunity
|
2007
|
12.12
|
|
2
|
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity.
|
Nature
|
2002
|
11.79
|
|
3
|
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells.
|
J Immunol
|
2010
|
9.72
|
|
4
|
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.
|
Immunity
|
2002
|
8.28
|
|
5
|
Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling.
|
Nature
|
2010
|
7.50
|
|
6
|
Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype.
|
Blood
|
2007
|
5.88
|
|
7
|
TNF downmodulates the function of human CD4+CD25hi T-regulatory cells.
|
Blood
|
2006
|
4.63
|
|
8
|
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.
|
J Immunol
|
2004
|
4.62
|
|
9
|
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness.
|
J Exp Med
|
2002
|
4.56
|
|
10
|
Nonredundant roles for Stat5a/b in directly regulating Foxp3.
|
Blood
|
2007
|
4.50
|
|
11
|
Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells.
|
J Immunol
|
2007
|
4.12
|
|
12
|
Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy.
|
Immunity
|
2004
|
3.81
|
|
13
|
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway.
|
Blood
|
2007
|
3.33
|
|
14
|
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.
|
J Immunol
|
2004
|
3.15
|
|
15
|
Activation requirements for the induction of CD4+CD25+ T cell suppressor function.
|
Eur J Immunol
|
2004
|
2.99
|
|
16
|
Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance.
|
Semin Immunol
|
2004
|
2.88
|
|
17
|
Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node.
|
J Exp Med
|
2002
|
2.78
|
|
18
|
CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner.
|
J Exp Med
|
2008
|
2.72
|
|
19
|
GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells.
|
Proc Natl Acad Sci U S A
|
2009
|
2.51
|
|
20
|
Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease.
|
J Immunol
|
2002
|
2.51
|
|
21
|
The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells.
|
J Immunol
|
2004
|
2.50
|
|
22
|
Activated CD4+CD25+ T cells selectively kill B lymphocytes.
|
Blood
|
2006
|
2.42
|
|
23
|
Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells.
|
J Immunol
|
2007
|
2.32
|
|
24
|
The percentage of FoxP3+Helios+ Treg cells correlates positively with disease activity in systemic lupus erythematosus.
|
Arthritis Rheum
|
2013
|
2.29
|
|
25
|
Regulatory T cells: recommendations to simplify the nomenclature.
|
Nat Immunol
|
2013
|
2.13
|
|
26
|
The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases.
|
Immunity
|
2008
|
2.04
|
|
27
|
In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients.
|
J Clin Invest
|
2005
|
1.96
|
|
28
|
IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo.
|
J Immunol
|
2011
|
1.89
|
|
29
|
CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence.
|
J Exp Med
|
2006
|
1.88
|
|
30
|
Selective expression of latency-associated peptide (LAP) and IL-1 receptor type I/II (CD121a/CD121b) on activated human FOXP3+ regulatory T cells allows for their purification from expansion cultures.
|
Blood
|
2009
|
1.83
|
|
31
|
TGF-beta-induced Foxp3+ regulatory T cells rescue scurfy mice.
|
Eur J Immunol
|
2008
|
1.80
|
|
32
|
Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells.
|
Nat Immunol
|
2012
|
1.74
|
|
33
|
T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.
|
Nature
|
2008
|
1.68
|
|
34
|
Regulatory/suppressor T cells in health and disease.
|
Arthritis Rheum
|
2004
|
1.65
|
|
35
|
What does the future hold for cell-based tolerogenic therapy?
|
Nat Rev Immunol
|
2007
|
1.64
|
|
36
|
Th1, Th2, and Th17 effector T cell-induced autoimmune gastritis differs in pathological pattern and in susceptibility to suppression by regulatory T cells.
|
J Immunol
|
2008
|
1.63
|
|
37
|
Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.
|
J Exp Med
|
2009
|
1.61
|
|
38
|
Cutting edge: antigen-specific TGF beta-induced regulatory T cells suppress Th17-mediated autoimmune disease.
|
J Immunol
|
2008
|
1.61
|
|
39
|
Distinct subsets of FoxP3+ regulatory T cells participate in the control of immune responses.
|
J Immunol
|
2007
|
1.56
|
|
40
|
Polyclonal Treg cells enhance the activity of a mucosal adjuvant.
|
Immunol Cell Biol
|
2010
|
1.52
|
|
41
|
CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells.
|
J Immunol
|
2005
|
1.49
|
|
42
|
TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation.
|
Eur J Immunol
|
2005
|
1.46
|
|
43
|
Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells.
|
J Immunol
|
2005
|
1.43
|
|
44
|
Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens.
|
Proc Natl Acad Sci U S A
|
2011
|
1.41
|
|
45
|
Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.
|
J Immunol
|
2009
|
1.39
|
|
46
|
Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion.
|
Blood
|
2012
|
1.36
|
|
47
|
CD4+ T-cell development in a mouse expressing a transgenic TCR derived from a Treg.
|
Eur J Immunol
|
2009
|
1.36
|
|
48
|
Engagement of TLR2 does not reverse the suppressor function of mouse regulatory T cells, but promotes their survival.
|
J Immunol
|
2009
|
1.32
|
|
49
|
Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation.
|
J Immunol
|
2013
|
1.19
|
|
50
|
Therapeutic potential of FOXP3(+) regulatory T cells and their interactions with dendritic cells.
|
Hum Immunol
|
2009
|
1.17
|
|
51
|
Simvastatin induces Foxp3+ T regulatory cells by modulation of transforming growth factor-beta signal transduction.
|
Immunology
|
2010
|
1.15
|
|
52
|
Antigen-specific induced T regulatory cells impair dendritic cell function via an IL-10/MARCH1-dependent mechanism.
|
J Immunol
|
2013
|
1.13
|
|
53
|
Fatal attraction: tumors beckon regulatory T cells.
|
Nat Med
|
2004
|
1.13
|
|
54
|
The role of suppressor T cells in regulation of immune responses.
|
J Allergy Clin Immunol
|
2002
|
1.12
|
|
55
|
Role of IFN-gamma in Th1 differentiation: IFN-gamma regulates IL-18R alpha expression by preventing the negative effects of IL-4 and by inducing/maintaining IL-12 receptor beta 2 expression.
|
J Immunol
|
2002
|
1.11
|
|
56
|
Highlights of 10 years of immunology in Nature Reviews Immunology.
|
Nat Rev Immunol
|
2011
|
1.06
|
|
57
|
Cutting Edge: IL-10-producing CD4+ T cells mediate tumor rejection.
|
J Immunol
|
2002
|
1.05
|
|
58
|
Bone marrow-derived dendritic cells reverse the anergic state of CD4+CD25+ T cells without reversing their suppressive function.
|
J Immunol
|
2005
|
1.04
|
|
59
|
CD4+ CD25+ [corrected] regulatory T cells render naive CD4+ CD25- T cells anergic and suppressive.
|
Immunology
|
2007
|
1.04
|
|
60
|
Modulation of Treg cells/T effector function by GITR signaling is context-dependent.
|
Eur J Immunol
|
2013
|
0.99
|
|
61
|
CD4+CD25+ regulatory T cells are activated in vivo by recognition of self.
|
Int Immunol
|
2007
|
0.99
|
|
62
|
Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry.
|
Cancer Immunol Immunother
|
2015
|
0.99
|
|
63
|
Costimulatory effects of IL-1 on the expansion/differentiation of CD4+CD25+Foxp3+ and CD4+CD25+Foxp3- T cells.
|
J Leukoc Biol
|
2008
|
0.94
|
|
64
|
Autoantibodies in scurfy mice and IPEX patients recognize keratin 14.
|
J Invest Dermatol
|
2010
|
0.94
|
|
65
|
Polyclonal Treg cells modulate T effector cell trafficking.
|
Eur J Immunol
|
2011
|
0.92
|
|
66
|
Activated T cells express the OX40 ligand: requirements for induction and costimulatory function.
|
Immunology
|
2006
|
0.92
|
|
67
|
The IL-10-producing competence of Th2 cells generated in vitro is IL-4 dependent.
|
Eur J Immunol
|
2002
|
0.92
|
|
68
|
A self-reactive TCR drives the development of Foxp3+ regulatory T cells that prevent autoimmune disease.
|
J Immunol
|
2011
|
0.91
|
|
69
|
Transforming growth factor-beta1 enhances the interferon-gamma-dependent, interleukin-12-independent pathway of T helper 1 cell differentiation.
|
Immunology
|
2005
|
0.91
|
|
70
|
The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells.
|
J Biol Chem
|
2011
|
0.89
|
|
71
|
Endogenous mouse mammary tumor viruses (mtv): new roles for an old virus in cancer, infection, and immunity.
|
Front Oncol
|
2013
|
0.88
|
|
72
|
Foxp3+ regulatory T cells: selfishness under scrutiny.
|
Immunity
|
2007
|
0.88
|
|
73
|
Spontaneous organ-specific Th2-mediated autoimmunity in TCR transgenic mice.
|
J Immunol
|
2004
|
0.87
|
|
74
|
A novel protective model against experimental allergic encephalomyelitis in mice expressing a transgenic TCR-specific for myelin oligodendrocyte glycoprotein.
|
J Neuroimmunol
|
2004
|
0.82
|
|
75
|
Promiscuous thymic expression of an autoantigen gene does not result in negative selection of pathogenic T cells.
|
J Immunol
|
2005
|
0.82
|
|
76
|
Differentiated Th1 autoreactive effector cells can induce experimental autoimmune encephalomyelitis in the absence of IL-12 and CD40/CD40L interactions.
|
J Neuroimmunol
|
2002
|
0.80
|
|
77
|
Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis.
|
Eur J Immunol
|
2008
|
0.80
|
|
78
|
Pre-differentiated Th1 and Th17 effector T cells in autoimmune gastritis: Ag-specific regulatory T cells are more potent suppressors than polyclonal regulatory T cells.
|
Int Immunopharmacol
|
2009
|
0.79
|
|
79
|
CD4+CD25+ T regulatory cells limit effector T cells and favor the progression of brucellosis in BALB/c mice.
|
Microbes Infect
|
2009
|
0.78
|
|
80
|
Eos, goddess of treg cell reprogramming.
|
Immunity
|
2013
|
0.75
|