Published in Circulation on June 13, 2005
Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency. Bioconjug Chem (2009) 1.88
Multimodality cardiovascular molecular imaging, Part II. Circ Cardiovasc Imaging (2009) 1.82
Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis. Proc Natl Acad Sci U S A (2009) 1.72
Radiolabeled arginine-glycine-aspartic acid peptides to image angiogenesis in swine model of hibernating myocardium. JACC Cardiovasc Imaging (2008) 1.57
Radiolabelled RGD peptides for imaging and therapy. Eur J Nucl Med Mol Imaging (2012) 1.33
PET and SPECT in cardiovascular molecular imaging. Nat Rev Cardiol (2009) 1.26
Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo. Blood (2007) 1.19
Radionuclide imaging: a molecular key to the atherosclerotic plaque. J Am Coll Cardiol (2008) 1.08
Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography. Circulation (2008) 1.07
Imaging of the unstable plaque: how far have we got? Eur Heart J (2009) 1.06
Serial noninvasive targeted imaging of peripheral angiogenesis: validation and application of a semiautomated quantitative approach. J Nucl Med (2009) 1.02
Analysis of angiogenesis induced by local IGF-1 expression after myocardial infarction using microSPECT-CT imaging. J Mol Cell Cardiol (2009) 1.01
Integrin-targeted imaging of inflammation in vascular remodeling. Arterioscler Thromb Vasc Biol (2011) 0.96
PET/SPECT imaging of hindlimb ischemia: focusing on angiogenesis and blood flow. Angiogenesis (2012) 0.95
Molecular imaging of inflammation and intraplaque vasa vasorum: a step forward to identification of vulnerable plaques? J Nucl Cardiol (2010) 0.93
Endothelial-derived neuregulin is an important mediator of ischaemia-induced angiogenesis and arteriogenesis. Cardiovasc Res (2011) 0.92
Targeting the alphavbeta3 integrin for small-animal PET/CT of osteolytic bone metastases. J Nucl Med (2009) 0.91
Molecular imaging of angiogenesis with SPECT. Eur J Nucl Med Mol Imaging (2010) 0.90
Early molecular imaging of interstitial changes in patients after myocardial infarction: comparison with delayed contrast-enhanced magnetic resonance imaging. J Nucl Cardiol (2010) 0.90
Molecular imaging of angiogenic therapy in peripheral vascular disease with alphanubeta3-integrin-targeted nanoparticles. Magn Reson Med (2010) 0.90
Targeted molecular imaging of angiogenesis in PET and SPECT: a review. Yale J Biol Med (2012) 0.87
Radiolabeled Cyclic RGD Peptide Bioconjugates as Radiotracers Targeting Multiple Integrins. Bioconjug Chem (2015) 0.86
Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesis. Am J Pathol (2014) 0.85
Characterization of the arterial anatomy of the murine hindlimb: functional role in the design and understanding of ischemia models. PLoS One (2013) 0.84
Specific uptake of 99mTc-NC100692, an αvβ3-targeted imaging probe, in subcutaneous and orthotopic tumors. Nucl Med Biol (2013) 0.81
In vivo molecular imaging of vascular stress. Cell Stress Chaperones (2008) 0.78
MEK inhibitors, novel anti-adhesive molecules, reduce sickle red blood cell adhesion in vitro and in vivo, and vasoocclusion in vivo. PLoS One (2014) 0.78
Image-guided pro-angiogenic therapy in diabetic stroke mouse models using a multi-modal nanoprobe. Theranostics (2014) 0.78
Imaging the effect of receptor for advanced glycation endproducts on angiogenic response to hindlimb ischemia in diabetes. EJNMMI Res (2011) 0.78
The role of molecular imaging in the evaluation of myocardial and peripheral angiogenesis. Ann Nucl Med (2015) 0.77
Novel Applications of Radionuclide Imaging in Peripheral Vascular Disease. Cardiol Clin (2015) 0.76
Imaging of angiogenesis in cardiology. Eur J Nucl Med Mol Imaging (2007) 0.76
Molecular Imaging of Angiogenesis and Vascular Remodeling in Cardiovascular Pathology. J Clin Med (2016) 0.75
SPECT and PET imaging of angiogenesis and arteriogenesis in pre-clinical models of myocardial ischemia and peripheral vascular disease. Eur J Nucl Med Mol Imaging (2016) 0.75
Non-invasive Monitoring of Angiogenesis in Cardiology. Curr Cardiovasc Imaging Rep (2009) 0.75
Molecular images of neovascularization: art for art's sake or form with a function? Circulation (2005) 0.75
SPECT Imaging of 2-D and 3-D Distributed Sources with Near-Field Coded Aperture Collimation: Computer Simulation and Real Data Validation. J Med Biol Eng (2016) 0.75
Evaluation of ανβ3-mediated tumor expression with a 99mTc-labeled ornithine-modified RGD derivative during glioblastoma growth in vivo. Cancer Biother Radiopharm (2014) 0.75
Comparison of Tc-99m maraciclatide and Tc-99m sestamibi molecular breast imaging in patients with suspected breast cancer. EJNMMI Res (2017) 0.75
αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice. EJNMMI Res (2016) 0.75
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. J Clin Invest (2002) 2.50
Detection of herpes simplex virus type 2-specific immunoglobulin G antibodies in African sera by using recombinant gG2, Western blotting, and gG2 inhibition. J Clin Microbiol (2002) 2.39
Differential effect of 180 degrees and 360 degrees acquisition orbits on the accuracy of SPECT imaging: quantitative evaluation in phantoms. J Nucl Med (2002) 2.35
Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction. Am J Physiol Heart Circ Physiol (2005) 2.23
Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction. J Clin Invest (2004) 2.06
Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors. J Clin Oncol (2012) 2.04
A Hough transform global probabilistic approach to multiple-subject diffusion MRI tractography. Med Image Anal (2011) 1.98
PECAM-1: old friend, new partners. Curr Opin Cell Biol (2003) 1.96
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model. Biomaterials (2007) 1.90
Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling. Circulation (2005) 1.82
Multimodality cardiovascular molecular imaging, Part II. Circ Cardiovasc Imaging (2009) 1.82
Estimation of 3-D left ventricular deformation from medical images using biomechanical models. IEEE Trans Med Imaging (2002) 1.82
Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system. J Biol Chem (2002) 1.79
Common Alzheimer's disease risk variant within the CLU gene affects white matter microstructure in young adults. J Neurosci (2011) 1.74
Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice. Am J Pathol (2005) 1.65
Development of brain structural connectivity between ages 12 and 30: a 4-Tesla diffusion imaging study in 439 adolescents and adults. Neuroimage (2012) 1.60
HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. Proc Natl Acad Sci U S A (2007) 1.58
Detection of injury-induced vascular remodeling by targeting activated alphavbeta3 integrin in vivo. Circulation (2004) 1.57
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev Cell (2013) 1.54
Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel. FASEB J (2011) 1.52
A macroporous hydrogel for the coculture of neural progenitor and endothelial cells to form functional vascular networks in vivo. Proc Natl Acad Sci U S A (2006) 1.52
Matrix metalloproteinase 9 facilitates West Nile virus entry into the brain. J Virol (2008) 1.49
Effectiveness of regional DTI measures in distinguishing Alzheimer's disease, MCI, and normal aging. Neuroimage Clin (2013) 1.49
Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects. Neuroimage (2011) 1.48
MISAGO 2: one-year outcomes after implantation of the Misago self-expanding nitinol stent in the superficial femoral and popliteal arteries of 744 patients. J Endovasc Ther (2012) 1.48
Forkhead box protein P1 as a downstream target of transforming growth factor-β induces collagen synthesis and correlates with a more stable plaque phenotype. Atherosclerosis (2011) 1.48
Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice. J Leukoc Biol (2006) 1.48
Effects of adenosine and a selective A2A adenosine receptor agonist on hemodynamic and thallium-201 and technetium-99m-sestaMIBI biodistribution and kinetics. JACC Cardiovasc Imaging (2009) 1.48
Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis. J Clin Invest (2006) 1.46
Differential expression of GAPDH and beta3-actin in growing collateral arteries. Mol Cell Biochem (2002) 1.45
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy. Proc Natl Acad Sci U S A (2002) 1.41
Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: the EXAMI study. Int J Cardiol (2012) 1.41
Breakdown of brain connectivity between normal aging and Alzheimer's disease: a structural k-core network analysis. Brain Connect (2013) 1.40
Fibroblast-type reticular stromal cells regulate the lymph node vasculature. J Immunol (2008) 1.39
How does angular resolution affect diffusion imaging measures? Neuroimage (2009) 1.37
Molecular imaging of activated matrix metalloproteinases in vascular remodeling. Circulation (2008) 1.37
Third-generation beta-blockers stimulate nitric oxide release from endothelial cells through ATP efflux: a novel mechanism for antihypertensive action. Circulation (2003) 1.36
Modeling the neurovascular niche: VEGF- and BDNF-mediated cross-talk between neural stem cells and endothelial cells: an in vitro study. J Neurosci Res (2006) 1.35
Two genetic variants of CD38 in subjects with autism spectrum disorder and controls. Neurosci Res (2010) 1.35
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. J Clin Invest (2012) 1.34
Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells. J Biol Chem (2004) 1.34
Genetics of the connectome. Neuroimage (2013) 1.33
Interferon-beta signaling is enhanced in patients with insufficient coronary collateral artery development and inhibits arteriogenesis in mice. Circ Res (2008) 1.32
Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions. Brain Pathol (2010) 1.31
Modeling of longitudinal academic achievement scores after pediatric traumatic brain injury. Dev Neuropsychol (2004) 1.30
Altered structural brain connectivity in healthy carriers of the autism risk gene, CNTNAP2. Brain Connect (2011) 1.29
Elevated glucose inhibits VEGF-A-mediated endocardial cushion formation: modulation by PECAM-1 and MMP-2. J Cell Biol (2003) 1.28
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity. FASEB J (2004) 1.26
Exogenous application of transforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation. FASEB J (2002) 1.26
PET and SPECT in cardiovascular molecular imaging. Nat Rev Cardiol (2009) 1.26
HMG CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation. FASEB J (2005) 1.25
MAPKs (ERK1/2, p38) and AKT can be phosphorylated by shear stress independently of platelet endothelial cell adhesion molecule-1 (CD31) in vascular endothelial cells. J Biol Chem (2005) 1.25
Characterization of the natural history of extracellular matrix production in tissue-engineered vascular grafts during neovessel formation. Cells Tissues Organs (2011) 1.24
Report of the National Heart, Lung, and Blood Institute working group on the translation of cardiovascular molecular imaging. Circulation (2011) 1.23
Neural guidance molecules, tip cells, and mechanical factors in vascular development. Cardiovasc Res (2008) 1.22
Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration. Proc Natl Acad Sci U S A (2011) 1.20
Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho. FASEB J (2003) 1.20
Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis. Circulation (2002) 1.19
Gamma delta T cells facilitate adaptive immunity against West Nile virus infection in mice. J Immunol (2006) 1.18
Arteriogenesis proceeds via ICAM-1/Mac-1- mediated mechanisms. Circ Res (2004) 1.18
Magnetic resonance field strength effects on diffusion measures and brain connectivity networks. Brain Connect (2013) 1.16
Modulation of collateral artery growth in a porcine hindlimb ligation model using MCP-1. Am J Physiol Heart Circ Physiol (2002) 1.16
TH1 immune responses to fully MHC mismatched allografts are diminished in the absence of MyD88, a toll-like receptor signal adaptor protein. Am J Transplant (2004) 1.16
Lack of platelet endothelial cell adhesion molecule-1 attenuates foreign body inflammation because of decreased angiogenesis. Am J Pathol (2003) 1.16
Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. Neuroimage (2009) 1.15
Angular versus spatial resolution trade-offs for diffusion imaging under time constraints. Hum Brain Mapp (2012) 1.15
Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response. J Clin Invest (2005) 1.15
Hierarchical topological network analysis of anatomical human brain connectivity and differences related to sex and kinship. Neuroimage (2011) 1.12
SMALL WORLD NETWORK MEASURES PREDICT WHITE MATTER DEGENERATION IN PATIENTS WITH EARLY-STAGE MILD COGNITIVE IMPAIRMENT. Proc IEEE Int Symp Biomed Imaging (2012) 1.12
TNF-alpha induces MMP2 gelatinase activity and MT1-MMP expression in an in vitro model of nucleus pulposus tissue degeneration. Spine (Phila Pa 1976) (2008) 1.12
Magnetic resonance imaging-defined areas of microvascular obstruction after acute myocardial infarction represent microvascular destruction and haemorrhage. Eur Heart J (2013) 1.11
PECAM-1 affects GSK-3beta-mediated beta-catenin phosphorylation and degradation. Am J Pathol (2006) 1.11
Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis. Eur Heart J (2011) 1.10
Discovery and Replication of Gene Influences on Brain Structure Using LASSO Regression. Front Neurosci (2012) 1.10
Cardiac restricted overexpression of membrane type-1 matrix metalloproteinase causes adverse myocardial remodeling following myocardial infarction. J Biol Chem (2010) 1.09
Tracking medication information across medical records. AMIA Annu Symp Proc (2009) 1.09
Test-retest reliability of graph theory measures of structural brain connectivity. Med Image Comput Comput Assist Interv (2012) 1.08
Disrupted synaptic development in the hypoxic newborn brain. Proc Natl Acad Sci U S A (2002) 1.08
Multimodality imaging of myocardial injury and remodeling. J Nucl Med (2010) 1.08
Abnormal monocyte recruitment and collateral artery formation in monocyte chemoattractant protein-1 deficient mice. Vasc Med (2004) 1.08
Histamine inhibits conducted vasodilation through endothelium-derived NO production in arterioles of mouse skeletal muscle. FASEB J (2004) 1.07
A non-parametric vessel detection method for complex vascular structures. Med Image Anal (2008) 1.07
Development of a model system for preliminary evaluation of tissue-engineered vascular conduits. J Pediatr Surg (2006) 1.06