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1
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A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.
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J Neurosci
|
2005
|
2.81
|
|
2
|
A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit.
|
Mol Pharmacol
|
2002
|
1.47
|
|
3
|
Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment.
|
Mol Pharmacol
|
2008
|
1.23
|
|
4
|
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
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J Biol Chem
|
2013
|
1.22
|
|
5
|
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines.
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Proc Natl Acad Sci U S A
|
2012
|
1.22
|
|
6
|
Collecting saliva by mail for genetic and cotinine analyses in participants recruited through the Internet.
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Eur J Epidemiol
|
2005
|
1.14
|
|
7
|
Potentiation of human alpha4beta2 neuronal nicotinic acetylcholine receptor by estradiol.
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Mol Pharmacol
|
2002
|
1.12
|
|
8
|
Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.
|
J Med Chem
|
2009
|
1.11
|
|
9
|
EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.
|
Neuropharmacology
|
2011
|
1.09
|
|
10
|
Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathogenic nicotinic acetylcholine receptor beta-subunit mutations outside the ion channel pore.
|
Mol Pharmacol
|
2008
|
1.07
|
|
11
|
Molecular characterization of off-target activities of telithromycin: a potential role for nicotinic acetylcholine receptors.
|
Antimicrob Agents Chemother
|
2010
|
0.96
|
|
12
|
Identification of molluscan nicotinic acetylcholine receptor (nAChR) subunits involved in formation of cation- and anion-selective nAChRs.
|
J Neurosci
|
2005
|
0.94
|
|
13
|
Identification and functional expression of a family of nicotinic acetylcholine receptor subunits in the central nervous system of the mollusc Lymnaea stagnalis.
|
J Biol Chem
|
2005
|
0.94
|
|
14
|
The CHRNB2 mutation I312M is associated with epilepsy and distinct memory deficits.
|
Neurobiol Dis
|
2005
|
0.94
|
|
15
|
Discovery of α7-nicotinic receptor ligands by virtual screening of the chemical universe database GDB-13.
|
J Chem Inf Model
|
2011
|
0.87
|
|
16
|
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors.
|
Bioorg Med Chem
|
2011
|
0.87
|
|
17
|
Synthesis and nicotinic receptor activity of chemical space analogues of N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide (PNU-282,987) and 1,4-diazabicyclo[3.2.2]nonane-4-carboxylic acid 4-bromophenyl ester (SSR180711).
|
J Med Chem
|
2012
|
0.86
|
|
18
|
A new Chrna4 mutation with low penetrance in nocturnal frontal lobe epilepsy.
|
Epilepsia
|
2003
|
0.86
|
|
19
|
Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors.
|
FASEB J
|
2011
|
0.86
|
|
20
|
Fluorescent epibatidine agonists for neuronal and muscle-type nicotinic acetylcholine receptors.
|
Angew Chem Int Ed Engl
|
2007
|
0.85
|
|
21
|
Probing the reorganization of the nicotinic acetylcholine receptor during desensitization by time-resolved covalent labeling using [3H]AC5, a photoactivatable agonist.
|
Mol Pharmacol
|
2005
|
0.85
|
|
22
|
Discovery of potent positive allosteric modulators of the α3β2 nicotinic acetylcholine receptor by a chemical space walk in ChEMBL.
|
ACS Chem Neurosci
|
2014
|
0.84
|
|
23
|
Functional properties of neuronal nicotinic acetylcholine receptors in the chick retina during development.
|
Eur J Neurosci
|
2005
|
0.84
|
|
24
|
Discovery of NMDA glycine site inhibitors from the chemical universe database GDB.
|
ChemMedChem
|
2008
|
0.83
|
|
25
|
3-(aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDB.
|
Bioorg Med Chem Lett
|
2009
|
0.79
|
|
26
|
A-186253, a specific antagonist of the alpha 4 beta 2 nAChRs: its properties and potential to study brain nicotinic acetylcholine receptors.
|
Neuropharmacology
|
2004
|
0.79
|
|
27
|
Mutations in familial nocturnal frontal lobe epilepsy might be associated with distinct neurological phenotypes.
|
Seizure
|
2011
|
0.79
|
|
28
|
Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor.
|
J Neurochem
|
2007
|
0.76
|
|
29
|
Structural reorganization of the acetylcholine binding site of the torpedo nicotinic receptor as revealed by dynamic photoaffinity labeling.
|
Chembiochem
|
2002
|
0.76
|
|
30
|
Identification of a novel member of the CLIC family, CLIC6, mapping to 21q22.12.
|
Gene
|
2003
|
0.75
|
|
31
|
Unexpected sensitivity of the human alpha7 neuronal nicotinic acetylcholine receptor to aminoglycosides.
|
Neuroreport
|
2006
|
0.75
|
|
32
|
Engineered site-directed labeling of nicotinic acetylcholine receptors using reactive epibatidine derivatives: appraisal of epibatidine-docking models in neuronal and muscular receptors.
|
J Mol Neurosci
|
2006
|
0.75
|
|
33
|
Reorganization of the nicotinic acetylcholine receptor during desensitization probed with a photoactivatable agonist.
|
J Mol Neurosci
|
2006
|
0.75
|
|
34
|
Syntheses and biological properties of cysteine-reactive epibatidine derivatives.
|
Bioorg Med Chem Lett
|
2003
|
0.75
|